KEGG   PATHWAY: lmi00630
Entry
lmi00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Leishmania mexicana
Class
Metabolism; Carbohydrate metabolism
Pathway map
lmi00630  Glyoxylate and dicarboxylate metabolism
lmi00630

Module
lmi_M00621  Glycine cleavage system [PATH:lmi00630]
lmi_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:lmi00630]
Other DBs
GO: 0046487 0043648
Organism
Leishmania mexicana [GN:lmi]
Gene
LMXM_23_0540  putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
LMXM_23_0710  putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
LMXM_28_2860  putative cytosolic malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
LMXM_33_0130  putative malate dehydrogenase [KO:K00026] [EC:1.1.1.37]
LMXM_33_0140  malate dehydrogenase [KO:K00026] [EC:1.1.1.37]
LMXM_33_0150  putative malate dehydrogenase [KO:K00026] [EC:1.1.1.37]
LMXM_33_0160  putative malate dehydrogenase [KO:K00026] [EC:1.1.1.37]
LMXM_19_0710  glycosomal malate dehydrogenase [KO:K00026] [EC:1.1.1.37]
LMXM_18_0680  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
LMXM_18_0670  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
LMXM_18_0510  putative aconitase [KO:K01681] [EC:4.2.1.3]
LMXM_26_0020  methylmalonyl-coa epimerase-like protein [KO:K05606] [EC:5.1.99.1]
LMXM_01_0050  putative carboxylase [KO:K01965] [EC:6.4.1.3]
LMXM_28_0490  putative propionyl-coa carboxylase beta chain [KO:K01966] [EC:6.4.1.3 2.1.3.15]
LMXM_27_0300  putative methylmalonyl-coenzyme a mutase [KO:K01847] [EC:5.4.99.2]
LMXM_06_0370  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
LMXM_28_2370  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LMXM_14_1320  putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LMXM_26_0030  putative glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
LMXM_36_3800  aminomethyltransferase, mitochondrial precursor,putative [KO:K00605] [EC:2.1.2.10]
LMXM_36_3810  aminomethyltransferase, mitochondrial precursor,putative [KO:K00605] [EC:2.1.2.10]
LMXM_31_3310  putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
LMXM_30_2650  acetoin dehydrogenase e3 component-like protein [KO:K00382] [EC:1.8.1.4]
LMXM_30_2640  2-oxoglutarate dehydrogenase, e3 component,lipoamidedehydrogenase-like protein [KO:K00382] [EC:1.8.1.4]
LMXM_08_29_1830  putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
LMXM_34_4720  putative glycine cleavage system H protein [KO:K02437]
LMXM_29_0180  putative 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
lmi00010  Glycolysis / Gluconeogenesis
lmi00020  Citrate cycle (TCA cycle)
lmi00030  Pentose phosphate pathway
lmi00053  Ascorbate and aldarate metabolism
lmi00071  Fatty acid degradation
lmi00230  Purine metabolism
lmi00250  Alanine, aspartate and glutamate metabolism
lmi00260  Glycine, serine and threonine metabolism
lmi00620  Pyruvate metabolism
lmi00710  Carbon fixation by Calvin cycle
lmi00750  Vitamin B6 metabolism
lmi00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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