KEGG   PATHWAY: manc00061
Entry
manc00061                   Pathway                                
Name
Fatty acid biosynthesis - Massilia antarctica
Class
Metabolism; Lipid metabolism
Pathway map
manc00061  Fatty acid biosynthesis
manc00061

Module
manc_M00082  Fatty acid biosynthesis, initiation [PATH:manc00061]
manc_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:manc00061]
Other DBs
GO: 0006633
Organism
Massilia antarctica [GN:manc]
Gene
IV454_20760  acetyl-CoA carboxylase carboxyltransferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
IV454_03205  acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
IV454_03210  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
IV454_32020  acetyl-CoA carboxylase carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
IV454_08725  acetyl-CoA carboxylase carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
IV454_18425  fabD; ACP S-malonyltransferase [KO:K00645] [EC:2.3.1.39]
IV454_24845  acyltransferase domain-containing protein [KO:K00645] [EC:2.3.1.39]
IV454_18420  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
IV454_27290  beta-ketoacyl-ACP synthase [KO:K00647] [EC:2.3.1.41]
IV454_31480  hypothetical protein [KO:K00647] [EC:2.3.1.41]
IV454_10460  hypothetical protein [KO:K00647] [EC:2.3.1.41]
IV454_20140  hypothetical protein [KO:K00647] [EC:2.3.1.41]
IV454_27275  beta-ketoacyl-ACP synthase [KO:K09458] [EC:2.3.1.179]
IV454_18440  fabF; beta-ketoacyl-ACP synthase II [KO:K09458] [EC:2.3.1.179]
IV454_20125  beta-ketoacyl-[acyl-carrier-protein] synthase family protein [KO:K09458] [EC:2.3.1.179]
IV454_20130  hypothetical protein [KO:K09458] [EC:2.3.1.179]
IV454_20135  beta-ketoacyl-[acyl-carrier-protein] synthase family protein [KO:K09458] [EC:2.3.1.179]
IV454_27280  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
IV454_18430  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
IV454_20110  SDR family NAD(P)-dependent oxidoreductase [KO:K00059] [EC:1.1.1.100]
IV454_20145  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IV454_20175  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IV454_26750  fabZ; 3-hydroxyacyl-ACP dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
IV454_20120  fabZ; 3-hydroxyacyl-ACP dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
IV454_26440  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
IV454_05850  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
IV454_05855  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
IV454_08450  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
manc00020  Citrate cycle (TCA cycle)
manc00071  Fatty acid degradation
manc00410  beta-Alanine metabolism
manc00561  Glycerolipid metabolism
manc00564  Glycerophospholipid metabolism
manc00620  Pyruvate metabolism
manc00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

DBGET integrated database retrieval system