KEGG   PATHWAY: masi04980
Entry
masi04980                   Pathway                                
Name
Cobalamin transport and metabolism - Myxocyprinus asiaticus (Chinese sucker)
Class
Organismal Systems; Digestive system
Pathway map
masi04980  Cobalamin transport and metabolism
masi04980

Organism
Myxocyprinus asiaticus (Chinese sucker) [GN:masi]
Gene
127425591  transcobalamin-2 [KO:K14619]
127412427  lysosomal cobalamin transport escort protein LMBD1 [KO:K14617]
127414065  lysosomal cobalamin transport escort protein LMBD1-like [KO:K14617]
127432101  lysosomal cobalamin transporter ABCD4-like isoform X1 [KO:K05678] [EC:7.6.2.8]
127434428  lysosomal cobalamin transporter ABCD4-like isoform X1 [KO:K05678] [EC:7.6.2.8]
127409920  cyanocobalamin reductase / alkylcobalamin dealkylase [KO:K14618] [EC:1.16.1.6 2.5.1.151]
127438328  metabolism of cobalamin associated Da [KO:K26006]
127438787  cobalamin trafficking protein CblD-like [KO:K26006]
127447364  metabolism of cobalamin associated Db [KO:K26006]
127448097  methylmalonic aciduria and homocystinuria type D homolog, mitochondrial-like isoform X1 [KO:K26006]
127438650  corrinoid adenosyltransferase [KO:K00798] [EC:2.5.1.17]
127417043  corrinoid adenosyltransferase MMAB-like [KO:K00798] [EC:2.5.1.17]
127443915  methylmalonic aciduria type A protein, mitochondrial isoform X1 [KO:K07588] [EC:3.6.5.-]
127409855  methylmalonyl-CoA mutase, mitochondrial [KO:K01847] [EC:5.4.99.2]
127415647  methylmalonyl-CoA mutase, mitochondrial-like [KO:K01847] [EC:5.4.99.2]
127432104  methionine synthase reductase-like isoform X1 [KO:K00597] [EC:1.16.1.8]
127423503  methionine synthase isoform X1 [KO:K00548] [EC:2.1.1.13]
127412721  zinc finger protein 143a [KO:K20828]
127456393  zinc finger protein 143 isoform X1 [KO:K20828]
127439124  zinc finger protein 76-like isoform X1 [KO:K20828]
127416850  zinc finger protein 143 isoform X1 [KO:K20828]
127411521  zinc finger protein 143-like [KO:K20828]
127424422  host cell factor 1-like isoform X1 [KO:K14966]
127425837  host cell factor 1-like [KO:K14966]
127415006  host cell factor 1-like isoform X1 [KO:K14966]
127427743  host cell factor 1-like [KO:K14966]
127414119  THAP domain-containing protein 11-like [KO:K23211]
127414805  THAP domain-containing protein 11-like [KO:K23211]
127443805  peroxiredoxin-1-like [KO:K13279] [EC:1.11.1.24]
127445044  peroxiredoxin-1-like [KO:K13279] [EC:1.11.1.24]
127441021  peroxiredoxin-1-like [KO:K13279] [EC:1.11.1.24]
127442556  peroxiredoxin-1 [KO:K13279] [EC:1.11.1.24]
Compound
C00073  L-Methionine
C00091  Succinyl-CoA
C00101  Tetrahydrofolate
C00155  L-Homocysteine
C00194  Cobamide coenzyme
C00440  5-Methyltetrahydrofolate
C00541  Cob(II)alamin
C01213  (R)-Methylmalonyl-CoA
C02823  Cyanocobalamin
C06409  [Methionine synthase]-cob(II)alamin
C06410  [Methionine synthase]-methylcob(III)alamin
C06453  Methylcobalamin
C08230  Hydroxocobalamin
C22880  [Methionine synthase]-cob(I)alamin
Reference
PMID:35337617
  Authors
Nijland M, Martinez Felices JM, Slotboom DJ, Thangaratnarajah C
  Title
Membrane transport of cobalamin.
  Journal
Vitam Horm 119:121-148 (2022)
DOI:10.1016/bs.vh.2022.01.008
Reference
PMID:35337623
  Authors
Hannibal L, Jacobsen DW
  Title
Intracellular processing of vitamin B(12) by MMACHC (CblC).
  Journal
Vitam Horm 119:275-298 (2022)
DOI:10.1016/bs.vh.2022.02.001
Reference
PMID:35337626
  Authors
Watkins D, Rosenblatt DS
  Title
Inherited defects of cobalamin metabolism.
  Journal
Vitam Horm 119:355-376 (2022)
DOI:10.1016/bs.vh.2022.01.010
Reference
PMID:36422244
  Authors
Kosa M, Galla Z, Lenart I, Barath A, Grecso N, Racz G, Bereczki C, Monostori P
  Title
Vitamin B12 (Cobalamin): Its Fate from Ingestion to Metabolism with Particular Emphasis on Diagnostic Approaches of Acquired Neonatal/Infantile Deficiency  Detected by Newborn Screening.
  Journal
Metabolites 12:metabo12111104 (2022)
DOI:10.3390/metabo12111104
Reference
PMID:20301503
  Authors
Sloan JL, Carrillo N, Adams D, Venditti CP
  Title
Disorders of Intracellular Cobalamin Metabolism.
  Journal
GeneReviews(1993)
Reference
PMID:23539619
  Authors
Gherasim C, Lofgren M, Banerjee R
  Title
Navigating the B(12) road: assimilation, delivery, and disorders of cobalamin.
  Journal
J Biol Chem 288:13186-93 (2013)
DOI:10.1074/jbc.R113.458810
Related
pathway
masi00270  Cysteine and methionine metabolism
masi00280  Valine, leucine and isoleucine degradation
masi00670  One carbon pool by folate
masi04144  Endocytosis
KO pathway
ko04980   
LinkDB

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