Entry Name ABC transporters - Mannheimia varigena USDA-ARS-USMARC-1312
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Mannheimia varigena USDA-ARS-USMARC-1312 [GN:
mvg ]
Gene X874_11300 Sulfate ABC transporter, periplasmic sulfate-binding protein [KO:K23163 ]
X874_7260 Molybdate-binding periplasmic protein, ABC transporter [KO:K02020 ]
X874_11660 Binding-protein-dependent transport system inner membrane component [KO:K02011 ]
X874_5530 Spermidine/putrescine transport system permease protein PotC [KO:K11070 ]
X874_5540 Spermidine/putrescine ABC superfamily ATP binding cassette transporter, membrane protein [KO:K11071 ]
X874_14820 Maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
X874_4790 ABC-type transport system involved in resistance to organic solvent [KO:K07323 ]
X874_4780 ABC-type transport system involved in resistance to organic solvent [KO:K02067 ]
X874_850 Monosaccharide ABC transporter substrate-binding protein, CUT2 [KO:K10439 ]
X874_1670 Periplasmic binding protein/LacI transcriptional regulator [KO:K17208 ]
X874_8410 ABC-type phosphate transport system substrate-binding protein [KO:K02040 ]
X874_9950 bifunctional amino acid-binding protein/DNA-binding protein [KO:K01999 ]
X874_5510 Binding-protein-dependent transport system inner membrane component [KO:K15582 ]
X874_10970 dipeptide ABC superfamily ATP-binding cassette transporter, binding protein [KO:K19226 ]
X874_3710 ABC-type Fe3+-hydroxamate transport system, periplasmic component [KO:K23227 ]
X874_16300 Zinc (Zn2+) ABC superfamily ATP binding cassette transporter, binding protein [KO:K09815 ]
X874_15300 Lipoprotein releasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
X874_1300 Alpha-hemolysin translocation ATP-binding protein HlyB [KO:K11004 ]
X874_7200 microcin-H47 secretion/processing ATP-binding protein mchF [KO:K13409 ]
X874_10090 Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
