KEGG   PATHWAY: pdic03082
Entry
pdic03082                   Pathway                                
Name
ATP-dependent chromatin remodeling - Phyllostomus discolor (pale spear-nosed bat)
Class
Genetic Information Processing; Chromosome
Pathway map
pdic03082  ATP-dependent chromatin remodeling
pdic03082

Organism
Phyllostomus discolor (pale spear-nosed bat) [GN:pdic]
Gene
114502338  SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [KO:K11654] [EC:5.6.2.-]
114493429  BAZ1A; LOW QUALITY PROTEIN: bromodomain adjacent to zinc finger domain protein 1A [KO:K11655]
114497896  BAZ1B; tyrosine-protein kinase BAZ1B [KO:K11658]
114512719  BAZ2A; bromodomain adjacent to zinc finger domain protein 2A isoform X1 [KO:K15224]
114494191  BAZ2B; bromodomain adjacent to zinc finger domain protein 2B isoform X2 [KO:K26167]
114514745  CHRAC1; chromatin accessibility complex protein 1 isoform X2 [KO:K11656]
114508616  POLE3; DNA polymerase epsilon subunit 3 [KO:K02326] [EC:2.7.7.7]
114500367  RSF1; LOW QUALITY PROTEIN: remodeling and spacing factor 1 [KO:K11657]
114504515  SMARCA1; probable global transcription activator SNF2L1 isoform X1 [KO:K11727] [EC:5.6.2.-]
114504325  BPTF; nucleosome-remodeling factor subunit BPTF isoform X15 [KO:K11728]
114496344  RBBP4; histone-binding protein RBBP4 [KO:K10752]
114504655  RBBP7; histone-binding protein RBBP7 [KO:K11659]
114515256  C8H17orf49; chromatin complexes subunit BAP18 isoform X1 [KO:K23406]
114508466  cat eye syndrome critical region protein 2 isoform X1 [KO:K25830]
114515273  CHD3; chromodomain-helicase-DNA-binding protein 3 isoform X11 [KO:K11642] [EC:5.6.2.-]
114512672  CHD4; chromodomain-helicase-DNA-binding protein 4 isoform X4 [KO:K11643] [EC:5.6.2.-]
114496397  HDAC1; LOW QUALITY PROTEIN: histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
114494251  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
114506656  MBD2; methyl-CpG-binding domain protein 2 [KO:K11590]
114503089  MBD3; methyl-CpG-binding domain protein 3 isoform X1 [KO:K11591]
114492668  MTA1; LOW QUALITY PROTEIN: metastasis-associated protein MTA1 [KO:K11660]
114499264  MTA2; metastasis-associated protein MTA2 [KO:K11660]
114499834  MTA3; metastasis-associated protein MTA3 [KO:K11660]
114502320  GATAD2A; transcriptional repressor p66-alpha isoform X1 [KO:K23194]
114489226  GATAD2B; transcriptional repressor p66-beta isoform X1 [KO:K23194]
114504536  PHF6; PHD finger protein 6 isoform X2 [KO:K23310]
114509664  CDK2AP1; cyclin-dependent kinase 2-associated protein 1 isoform X2 [KO:K26454]
114503188  SMARCA4; transcription activator BRG1 isoform X3 [KO:K11647] [EC:5.6.2.-]
114498749  SMARCA2; probable global transcription activator SNF2L2 isoform X1 [KO:K11647] [EC:5.6.2.-]
114509278  SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 [KO:K11648]
114514095  SMARCC2; SWI/SNF complex subunit SMARCC2 isoform X1 [KO:K11649]
114501525  SMARCC1; SWI/SNF complex subunit SMARCC1 [KO:K11649]
114503309  SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 [KO:K11650]
114512706  SMARCD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 isoform X1 [KO:K11650]
114508073  SMARCD3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X1 [KO:K11650]
114503926  SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 [KO:K11651]
114504029  ACTG1; actin, cytoplasmic 2 [KO:K05692]
114509151  ACTB; actin, cytoplasmic 1 [KO:K05692]
114490469  actin-like protein 6A isoform X1 [KO:K11340]
114490795  actin-like protein 6A [KO:K11340]
114515180  actin-like protein 6A [KO:K11340]
114501632  ACTL6B; actin-like protein 6B isoform X1 [KO:K11652]
114511343  BCL7C; B-cell CLL/lymphoma 7 protein family member C [KO:K25605]
114499407  BCL7B; B-cell CLL/lymphoma 7 protein family member B [KO:K25605]
114509594  BCL7A; B-cell CLL/lymphoma 7 protein family member A isoform X1 [KO:K25605]
114506403  SS18L1; calcium-responsive transactivator [KO:K15623]
114507006  SS18; protein SSXT isoform X1 [KO:K15623]
114497988  ARID1A; AT-rich interactive domain-containing protein 1A isoform X1 [KO:K11653]
114493823  ARID1B; LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 1B [KO:K11653]
114510981  DPF1; zinc finger protein neuro-d4 isoform X2 [KO:K22198]
114492324  DPF3; zinc finger protein DPF3 [KO:K22198]
114499403  DPF2; zinc finger protein ubi-d4 isoform X1 [KO:K13196]
114512787  ARID2; AT-rich interactive domain-containing protein 2 isoform X1 [KO:K11765]
114501961  PBRM1; protein polybromo-1 [KO:K11757]
114488119  BRD7; bromodomain-containing protein 7 isoform X2 [KO:K11723]
114490090  PHF10; PHD finger protein 10 isoform X1 [KO:K22197]
114498587  BRD9; bromodomain-containing protein 9 isoform X1 [KO:K22184]
114511227  BICRA; BRD4-interacting chromatin-remodeling complex-associated protein isoform X2 [KO:K25612]
114493919  BICRAL; BRD4-interacting chromatin-remodeling complex-associated protein-like isoform X2 [KO:K25613]
114492228  INO80; LOW QUALITY PROTEIN: chromatin-remodeling ATPase INO80 [KO:K11665] [EC:5.6.2.-]
114499560  INO80B; INO80 complex subunit B [KO:K11666]
114506461  INO80C; INO80 complex subunit C [KO:K11667]
114493935  INO80D; INO80 complex subunit D [KO:K11668]
114507867  INO80E; INO80 complex subunit E isoform X1 [KO:K11669]
114511028  TFPT; TCF3 fusion partner isoform X1 [KO:K11670]
114509294  NFRKB; nuclear factor related to kappa-B-binding protein isoform X1 [KO:K11671]
114513180  MCRS1; microspherule protein 1 isoform X3 [KO:K11674]
114510257  LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase isozyme L5-like [KO:K05610] [EC:3.4.19.12]
114512400  UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1 [KO:K05610] [EC:3.4.19.12]
114506421  RUVBL1; ruvB-like 1 isoform X1 [KO:K04499] [EC:5.6.2.4]
114510952  RUVBL2; ruvB-like 2 isoform X1 [KO:K11338] [EC:5.6.2.3]
114507004  ACTR5; actin-related protein 5 isoform X1 [KO:K11672]
114501685  ACTR8; actin-related protein 8 isoform X2 [KO:K11673]
114491702  YY1; transcriptional repressor protein YY1 [KO:K09201]
114508387  ZFP42; zinc finger protein 42 homolog [KO:K09201]
114512589  LOW QUALITY PROTEIN: helicase SRCAP [KO:K11661] [EC:5.6.2.-]
114497765  DMAP1; DNA methyltransferase 1-associated protein 1 [KO:K11324]
114513673  YEATS4; YEATS domain-containing protein 4 [KO:K11341]
114488942  VPS72; vacuolar protein sorting-associated protein 72 homolog [KO:K11664]
118498087  histone H2A type 2-B [KO:K11251]
114488869  histone H2A type 2-C [KO:K11251]
114489251  histone H2A type 2-A [KO:K11251]
114489252  histone H2A type 2-A [KO:K11251]
114489387  histone H2A type 1 [KO:K11251]
114489388  histone H2A type 1 [KO:K11251]
114489389  histone H2A type 1 [KO:K11251]
114489390  histone H2A type 1 [KO:K11251]
114489391  histone H2A type 1 [KO:K11251]
114489404  histone H2A type 1-like [KO:K11251]
114489407  histone H2A, sperm-like [KO:K11251]
114489450  LOW QUALITY PROTEIN: histone H2A type 1-like [KO:K11251]
114489528  histone H2A type 1 isoform X1 [KO:K11251]
114489529  histone H2A type 1 [KO:K11251]
114489530  histone H2A type 1 [KO:K11251]
114489532  histone H2A type 1-H [KO:K11251]
114489533  histone H2A type 1-J [KO:K11251]
114497169  core histone macro-H2A.2 [KO:K11251]
114490230  histone H2A.V [KO:K11251]
114505113  histone H2A-Bbd type 2/3-like [KO:K11251]
114500449  histone H2A.Z-like [KO:K11251]
114505443  histone H2A-Bbd type 2/3-like [KO:K11251]
114505455  histone H2A-Bbd type 2/3-like [KO:K11251]
114515302  histone H2A type 3 [KO:K11251]
114492639  histone H2A.Z [KO:K11251]
114499681  histone H2AX [KO:K11251]
114513353  histone H2A.J [KO:K11251]
114509102  core histone macro-H2A.1 isoform X1 [KO:K11251]
114513479  ACTR6; actin-related protein 6 isoform X1 [KO:K11662]
114497669  ZNHIT1; zinc finger HIT domain-containing protein 1 [KO:K11663]
114489735  EP400; E1A-binding protein p400 isoform X1 [KO:K11320] [EC:5.6.2.-]
114510032  transformation/transcription domain-associated protein isoform X7 [KO:K08874]
114488585  MORF4L1; mortality factor 4-like protein 1 isoform X1 [KO:K11339]
114504607  MORF4L2; mortality factor 4-like protein 2 [KO:K11342]
114492481  mortality factor 4-like protein 2 [KO:K11342]
114506636  MRG/MORF4L-binding protein isoform X1 [KO:K11343]
114509194  BRD8; bromodomain-containing protein 8 isoform X1 [KO:K11321]
118497957  bromodomain-containing protein 8-like isoform X1 [KO:K11321]
114507632  ING3; inhibitor of growth protein 3 [KO:K11319]
114493087  EPC1; enhancer of polycomb homolog 1 isoform X1 [KO:K11322]
114493792  EPC2; enhancer of polycomb homolog 2 isoform X3 [KO:K11322]
114497873  MEAF6; chromatin modification-related protein MEAF6 isoform X3 [KO:K11344]
114499743  KAT5; histone acetyltransferase KAT5 isoform X1 [KO:K11304] [EC:2.3.1.48]
Reference
PMID:31769422
  Authors
Hasan N, Ahuja N
  Title
The Emerging Roles of ATP-Dependent Chromatin Remodeling Complexes in Pancreatic Cancer.
  Journal
Cancers (Basel) 11:cancers11121859 (2019)
DOI:10.3390/cancers11121859
Reference
PMID:32001526
  Authors
He S, Wu Z, Tian Y, Yu Z, Yu J, Wang X, Li J, Liu B, Xu Y
  Title
Structure of nucleosome-bound human BAF complex.
  Journal
Science 367:875-881 (2020)
DOI:10.1126/science.aaz9761
Reference
PMID:33941852
  Authors
Wanior M, Kramer A, Knapp S, Joerger AC
  Title
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy.
  Journal
Oncogene 40:3637-3654 (2021)
DOI:10.1038/s41388-021-01781-x
Reference
PMID:20493981
  Authors
Burgio G, Onorati MC, Corona DF
  Title
Chromatin remodeling regulation by small molecules and metabolites.
  Journal
Biochim Biophys Acta 1799:671-80 (2010)
DOI:10.1016/j.bbagrm.2010.05.007
KO pathway
ko03082   
LinkDB

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