KEGG   PATHWAY: pmib00630
Entry
pmib00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Proteus mirabilis BB2000
Class
Metabolism; Carbohydrate metabolism
Pathway map
pmib00630  Glyoxylate and dicarboxylate metabolism
pmib00630

Module
pmib_M00012  Glyoxylate cycle [PATH:pmib00630]
pmib_M00621  Glycine cleavage system [PATH:pmib00630]
Other DBs
GO: 0046487 0043648
Organism
Proteus mirabilis BB2000 [GN:pmib]
Gene
BB2000_2768  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BB2000_3051  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
BB2000_2769  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BB2000_3440  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BB2000_0631  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
BB2000_1340  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
BB2000_2112  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
BB2000_0005  bifunctional acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
BB2000_1847  katA; catalase [KO:K03781] [EC:1.11.1.6]
BB2000_1132  2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BB2000_2063  tkrA; 2-ketogluconate reductase (2-ketoaldonate reductase) [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BB2000_3047  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BB2000_2892  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BB2000_1983  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BB2000_2091  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BB2000_2093  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
BB2000_2118  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BB2000_2092  gcvH; glycine cleavage system protein H [KO:K02437]
BB2000_0053  garK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
BB2000_2220  eda; Khg/KdpG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BB2000_2766  eda; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BB2000_3124  fdoG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
BB2000_3125  fdoG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
BB2000_3123  fdoH; formate dehydrogenase-O beta subunit [KO:K00124]
BB2000_3122  fdoI; formate dehydrogenase-O subunit gamma [KO:K00127]
BB2000_1525  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pmib00010  Glycolysis / Gluconeogenesis
pmib00020  Citrate cycle (TCA cycle)
pmib00030  Pentose phosphate pathway
pmib00053  Ascorbate and aldarate metabolism
pmib00071  Fatty acid degradation
pmib00230  Purine metabolism
pmib00250  Alanine, aspartate and glutamate metabolism
pmib00260  Glycine, serine and threonine metabolism
pmib00620  Pyruvate metabolism
pmib00710  Carbon fixation by Calvin cycle
pmib00750  Vitamin B6 metabolism
pmib00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system