KEGG   PATHWAY: pstg00061
Entry
pstg00061                   Pathway                                
Name
Fatty acid biosynthesis - Phreatobacter stygius
Class
Metabolism; Lipid metabolism
Pathway map
pstg00061  Fatty acid biosynthesis
pstg00061

Module
pstg_M00082  Fatty acid biosynthesis, initiation [PATH:pstg00061]
pstg_M00083  Fatty acid biosynthesis, elongation [PATH:pstg00061]
pstg_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:pstg00061]
Other DBs
GO: 0006633
Organism
Phreatobacter stygius [GN:pstg]
Gene
E8M01_10735  acetyl-CoA carboxylase carboxyltransferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
E8M01_33085  accB; acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
E8M01_33090  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
E8M01_21880  acetyl-CoA carboxylase carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
E8M01_11495  biotin carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
E8M01_29805  fabD; ACP S-malonyltransferase [KO:K00645] [EC:2.3.1.39]
E8M01_34420  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
E8M01_08230  fabB; beta-ketoacyl-ACP synthase I [KO:K00647] [EC:2.3.1.41]
E8M01_21900  fabF; beta-ketoacyl-[acyl-carrier-protein] synthase II [KO:K09458] [EC:2.3.1.179]
E8M01_29820  fabF; beta-ketoacyl-[acyl-carrier-protein] synthase II [KO:K09458] [EC:2.3.1.179]
E8M01_02480  beta-ketoacyl-ACP synthase [KO:K09458] [EC:2.3.1.179]
E8M01_02485  beta-ketoacyl-ACP synthase [KO:K09458] [EC:2.3.1.179]
E8M01_03925  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_23615  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_23680  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_10890  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_11075  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_24545  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_00805  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_29810  fabG; 3-oxoacyl-[acyl-carrier-protein] reductase [KO:K00059] [EC:1.1.1.100]
E8M01_17685  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_24790  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_17935  SDR family NAD(P)-dependent oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_12055  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_19320  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_24355  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_05005  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_07530  3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
E8M01_08130  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_02475  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
E8M01_08235  fabA; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA [KO:K01716] [EC:4.2.1.59 5.3.3.14]
E8M01_02490  beta-hydroxyacyl-ACP dehydratase [KO:K02372] [EC:4.2.1.59]
E8M01_31880  fabZ; 3-hydroxyacyl-ACP dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
E8M01_12910  fabI; enoyl-ACP reductase FabI [KO:K00208] [EC:1.3.1.9 1.3.1.10]
E8M01_08225  fabI; enoyl-ACP reductase FabI [KO:K00208] [EC:1.3.1.9 1.3.1.10]
E8M01_13205  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_22725  acyl-CoA synthetase [KO:K01897] [EC:6.2.1.3]
E8M01_30675  pimA; dicarboxylate--CoA ligase PimA [KO:K01897] [EC:6.2.1.3]
E8M01_11475  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_08380  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_17535  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_05805  long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_05960  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_01965  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_03295  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_09625  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_06710  acyl--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_21635  acyl-CoA synthetase [KO:K01897] [EC:6.2.1.3]
E8M01_29565  AMP-dependent synthetase [KO:K01897] [EC:6.2.1.3]
E8M01_23475  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
PMID:12061798
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
PMID:12518017
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
PMID:11337402
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
PMID:17573542
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
PMID:30201289
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
PMID:25203508
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
PMID:19686777
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
PMID:27553474
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
pstg00020  Citrate cycle (TCA cycle)
pstg00071  Fatty acid degradation
pstg00410  beta-Alanine metabolism
pstg00561  Glycerolipid metabolism
pstg00564  Glycerophospholipid metabolism
pstg00620  Pyruvate metabolism
pstg00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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