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Entry
Name
ABC transporters - Sinorhizobium fredii NGR234
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Sinorhizobium fredii NGR234 [GN:
rhi ]
Gene
NGR_b11710 probable sulfate uptake ABC transporter, permease protein [KO:K02046 ]
NGR_b11700 probable sulfate uptake ABC transporter, permease protein [KO:K02047 ]
NGR_b06180 putative ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [KO:K15553 ]
NGR_c25630 putative ABC transporter; putative aliphatic sulfonates transporter [KO:K15554 ]
NGR_b06200 putative ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [KO:K15554 ]
NGR_c29840 modA; molybdenum ABC transporter, periplasmic binding protein [KO:K02020 ]
NGR_a03660 probable substrate-binding periplasmic component of ABC transporter [KO:K02012 ]
NGR_b14270 putative periplasmic spermidine/putrescine-binding protein or ABC transporter [KO:K11069 ]
NGR_b03630 predicted PotD, Spermidine/putrescine-binding periplasmic protein PotD [KO:K11069 ]
NGR_c04760 putative spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein [KO:K11069 ]
NGR_b14260 putative spermidine/putrescine ABC transporter, permease protein [KO:K11070 ]
NGR_b03610 predicted PotC, ABC-type spermidine/putrescine transport system, permease component II PotC [KO:K11070 ]
NGR_b14250 probable ABC transporter, putrescine transport system permease protein [KO:K11071 ]
NGR_b03620 putative PotB, ABC-type spermidine/putrescine transport system, permease component I PotB [KO:K11071 ]
NGR_b03640 predicted PotA, ABC-type spermidine/putrescine transport system, ATPase component PotA [KO:K11072 ] [EC:7.6.2.11 ]
NGR_c03280 spermidine/putrescine ABC transporter, periplasmic substrate-binding protein [KO:K11073 ]
NGR_c03310 potI; putrescine ABC transporter system permease protein PotI [KO:K11074 ]
NGR_c03300 potH; putrescine ABC transport system permease protein PotH [KO:K11075 ]
NGR_c23640 proline/glycine betaine ABC transporter, substrate-binding protein [KO:K02002 ]
NGR_b04860 predicted ABC-type proline/glycine betaine transport system, periplasmic component [KO:K02002 ]
NGR_b23450 probable amino acid ABC transporter, substrate-binding protein [KO:K02002 ]
NGR_c07960 hypothetical amino acid ABC-transporter ATP-binding protein [KO:K02001 ]
NGR_c23650 proline/glycine betaine ABC transporter, permease protein [KO:K02001 ]
NGR_c27410 putative glycine betaine/L-proline ABC transporter, permease protein [KO:K02001 ]
NGR_b04870 predicted ABC-type proline/glycine betaine transport system, permease component [KO:K02001 ]
NGR_c24710 ABC sorbitol/mannitol transporter, ATPase subunit [KO:K10111 ] [EC:7.5.2.-]
NGR_b17710 probable sugar ABC transporter, ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
NGR_c35250 putative sugar ABC transporter, ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
NGR_b23110 thuK; sugar ABC transporter, ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
NGR_b18550 probable sugar ABC transporter, ATP binding protein [KO:K10111 ] [EC:7.5.2.-]
NGR_c17800 putative ATP-binding component of ABC transporter [KO:K10112 ] [EC:7.5.2.-]
NGR_b11800 putative sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
NGR_b20710 sugar ABC transporter, ATP-binding protein, putative [KO:K10112 ] [EC:7.5.2.-]
NGR_b16030 probable sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
NGR_c33090 putative sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
NGR_c06700 hypothetical ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
NGR_b17490 putative sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
NGR_b19460 putative ATP-binding component of ABC transporter [KO:K10112 ] [EC:7.5.2.-]
NGR_b17480 putative sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
NGR_b04050 predicted MalK, ABC-type sugar transport systems, ATPase component MalK [KO:K10112 ] [EC:7.5.2.-]
NGR_c25500 putative ATP-binding component of ABC transporter [KO:K10112 ] [EC:7.5.2.-]
NGR_b20260 probable sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
NGR_a02170 probable ABC transporter ATP-binding protein y4oS [KO:K10112 ] [EC:7.5.2.-]
NGR_b11240 putative ATP-binding component of ABC transporter [KO:K10112 ] [EC:7.5.2.-]
NGR_b04060 predicted MalK, ABC-type sugar transport systems, ATPase component MalK [KO:K10112 ] [EC:7.5.2.-]
NGR_b12940 putative ATP-binding component of ABC transporter [KO:K10112 ] [EC:7.5.2.-]
NGR_b15540 probable sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
NGR_c35280 binding-protein-dependent transport systems inner membrane component [KO:K10118 ]
NGR_c35270 binding-protein-dependent transport systems inner membrane component [KO:K10119 ]
NGR_c24720 putative mannitol transmembrane permease component of ABC transporter [KO:K10229 ]
NGR_c03100 predicted alpha-glucoside ABC transporter, substrate-binding protein [KO:K10232 ]
NGR_c03110 predicted alpha-glucoside transport system permease protein [KO:K10233 ]
NGR_c03120 predicted alpha-glucoside ABC transport system permease protein [KO:K10234 ]
NGR_b23130 thuF; trehalose/maltose ABC transporter, permease protein [KO:K10237 ]
NGR_b23120 thuG; trehalose/maltose ABC transporter, permease protein [KO:K10238 ]
NGR_c24150 chvE; multiple sugar-binding periplasmic receptor ChvE precursor [KO:K10546 ]
NGR_c24140 putative ATP-binding component of ABC transporter protein [KO:K10548 ] [EC:7.5.2.-]
NGR_b03990 putative Med, uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein Med [KO:K07335 ]
NGR_b03970 putative uncharacterized ABC-type transport system, permease component [KO:K23536 ]
NGR_b03950 predicted ABC-type uncharacterized transport system, ATPase component [KO:K23537 ]
NGR_c17830 probable sugar ABC transporter, substrate-binding protein [KO:K17315 ]
NGR_c33070 binding-protein-dependent transport systems inner membrane component [KO:K17316 ]
NGR_c33080 binding-protein-dependent transport systems inner membrane component [KO:K17317 ]
NGR_c33680 periplasmic binding protein/LacI transcriptional regulator [KO:K10439 ]
NGR_a02500 conserved periplasmic solute-binding protein of ABC-transporter [KO:K10439 ]
NGR_b22390 putative sugar ABC transporter, substrate-binding protein [KO:K10439 ]
NGR_b15680 periplasmic sugar-binding protein of sugar ABC transporter [KO:K10439 ]
NGR_b21720 binding protein component precursor of ABC ribose transporter [KO:K10439 ]
NGR_c17380 putative ribose transport system, substrate-binding protein [KO:K10439 ]
NGR_b04380 putative Ribose/xylose/arabinose/galactoside ABC-type transport system, permease components AraH [KO:K10440 ]
NGR_b04290 predicted AraH, Ribose/xylose/arabinose/galactoside ABC-type transport system, permease components AraH [KO:K10440 ]
NGR_b15480 putative sugar uptake ABC transporter periplasmic solute-binding [KO:K23508 ]
NGR_c01100 periplasmic binding protein/LacI transcriptionalregulator [KO:K10552 ]
NGR_c01110 putative ribose transport system, inner-membrane translocator [KO:K10553 ]
NGR_c02450 rhamnose ABC transporter, periplasmic rhamnose-binding protein [KO:K10559 ]
NGR_c02460 rbsA2; ribose import ATP-binding protein RbsA1 [KO:K10562 ] [EC:7.5.2.-]
NGR_b22070 ribose ABC transporter, periplasmic ribose-binding protein [KO:K17202 ]
NGR_b20570 ribose/galactose/methyl galactoside import ATP-bindingprotein 2 [KO:K17215 ]
NGR_b02190 sugar ABC transporter, periplasmic sugar-binding protein, putative [KO:K17237 ]
NGR_c31000 putative periplasmic binding component of ABC transporter [KO:K17321 ]
NGR_c36790 binding-protein-dependent transport system inner membrane component [KO:K05814 ]
NGR_c36800 binding-protein-dependent transport system inner membrane component [KO:K05815 ]
NGR_c36810 ugpC; ABC transporter related sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K05816 ] [EC:7.6.2.10 ]
NGR_c01440 predicted phosphate ABC transporter, substrate-binding protein [KO:K02040 ]
NGR_b13320 putative PhnE protein, phosphonate ABC transporter, putative membrane protein [KO:K02042 ]
NGR_b06820 amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K10018 ]
NGR_b06830 predicted ABC-type arginine transport system, permease component [KO:K10020 ]
NGR_c13160 aapQ; putative amino-acid ABC transporter membrane protein [KO:K09970 ]
NGR_c13150 aapM; putative amino acid ABC transporter, permease protein [KO:K09971 ]
NGR_c20660 branched-chain amino acid ABC transporter, periplasmic substrate-binding protein [KO:K01999 ]
NGR_c06030 putative ABC branched-chain amino transporter, periplasmic binding protein [KO:K01999 ]
NGR_b15300 probable amino acid ABC transporter, substrate-binding protein [KO:K01999 ]
NGR_b14720 leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursor [KO:K01999 ]
NGR_c20670 branched-chain amino acid ABC transporter, permease protein [KO:K01997 ]
NGR_c06000 branched-chain amino acid ABC transporter, permease protein [KO:K01997 ]
NGR_c34340 putative branched-chain amino acid transport system / permease component [KO:K01997 ]
NGR_c20680 branched-chain amino acid ABC transporter, permease protein [KO:K01998 ]
NGR_c34350 putative branched-chain amino acid transport system / permease component [KO:K01998 ]
NGR_b16400 branched-chain amino acid ABC transporter, permease protein [KO:K01998 ]
NGR_b12620 branched-chain amino acid ABC transporter, permease protein [KO:K01998 ]
NGR_b14710 branched-chain amino acid ABC transporter, permease protein [KO:K01998 ]
NGR_c20690 livG; branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
NGR_b12630 probable branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
NGR_c34360 putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
NGR_c20700 livF; predicted branched-chain amino acid transport ATP-binding protein [KO:K01996 ]
NGR_c34370 putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
NGR_b12640 probable branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
NGR_c29420 metI; D-methionine transport system permease protein MetI [KO:K02072 ]
NGR_b21770 probable urea or short-chain amide ABC transporter, permease protein [KO:K11960 ]
NGR_b21760 probable urea or short-chain amide ABC transporter, permease protein [KO:K11961 ]
NGR_b21750 probable urea or short-chain amide ABC transporter, ATP-binding protein [KO:K11962 ]
NGR_b21740 probable urea or short-chain amide ABC transporter, ATP-binding protein [KO:K11963 ]
NGR_b13740 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein [KO:K15580 ]
NGR_b13760 ABC oligopeptide transporter, inner membrane subunit OppC [KO:K15582 ]
NGR_c03460 dppA; periplasmic dipeptide ABC transport protein precursor DppA [KO:K12368 ]
NGR_c03470 dppB; dipeptide ABC transport system permease protein DppB [KO:K12369 ]
NGR_c03480 dppC; dipeptide ABC transport system permease protein DppC [KO:K12370 ]
NGR_a00920 conserved periplasmic solute-binding protein of ABC-transporter [KO:K13893 ]
NGR_c34810 binding-protein-dependent transport systems inner membrane component [KO:K13894 ]
NGR_c34800 binding-protein-dependent transport systems inner membrane component [KO:K13895 ]
NGR_c17650 znuA; high-affinity zinc uptake system protein ZnuA precursor [KO:K09815 ]
NGR_c31020 putative iron transport protein, periplasmic-binding protein [KO:K11604 ]
NGR_c05060 bioM; putative biotin transporter, ATP binding protein BioM [KO:K16784 ] [EC:7.6.2.-]
NGR_b09440 rkpT2; RkpT2, cell surface polysaccharide export ABC-2 transporter [KO:K09688 ]
NGR_b09520 rkpT1; RkpT1, cell surface polysaccharide export ABC-2 transporter [KO:K09688 ]
NGR_a03450 nodJ; ABC-transporter permease NodJ; probably involved in secretion of Nodulation factor [KO:K09694 ]
NGR_a03440 nodI; ABC-transporter ATP-binding protein NodI; involved in secretion of Nodulation factor [KO:K09695 ]
NGR_c19790 macB; macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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