Entry
Name
ABC transporters - Sinorhizobium fredii NGR234
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Other DBs
Organism
Sinorhizobium fredii NGR234 [GN:
rhi ]
Gene
NGR_a03440 nodI; ABC-transporter ATP-binding protein NodI; involved in secretion of Nodulation factor [KO:K09695 ]
NGR_a03450 nodJ; ABC-transporter permease NodJ; probably involved in secretion of Nodulation factor [KO:K09694 ]
NGR_b09440 rkpT2; RkpT2, cell surface polysaccharide export ABC-2 transporter [KO:K09688 ]
NGR_b09520 rkpT1; RkpT1, cell surface polysaccharide export ABC-2 transporter [KO:K09688 ]
NGR_b23110 thuK; sugar ABC transporter, ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
NGR_b23120 thuG; trehalose/maltose ABC transporter, permease protein [KO:K10238 ]
NGR_b23130 thuF; trehalose/maltose ABC transporter, permease protein [KO:K10237 ]
NGR_c02460 rbsA2; ribose import ATP-binding protein RbsA1 [KO:K10562 ] [EC:7.5.2.-]
NGR_c03300 potH; putrescine ABC transport system permease protein PotH [KO:K11075 ]
NGR_c03310 potI; putrescine ABC transporter system permease protein PotI [KO:K11074 ]
NGR_c03460 dppA; periplasmic dipeptide ABC transport protein precursor DppA [KO:K12368 ]
NGR_c03470 dppB; dipeptide ABC transport system permease protein DppB [KO:K12369 ]
NGR_c03480 dppC; dipeptide ABC transport system permease protein DppC [KO:K12370 ]
NGR_c05060 bioM; putative biotin transporter, ATP binding protein BioM [KO:K16784 ] [EC:7.6.2.-]
NGR_c13150 aapM; putative amino acid ABC transporter, permease protein [KO:K09971 ]
NGR_c13160 aapQ; putative amino-acid ABC transporter membrane protein [KO:K09970 ]
NGR_c17650 znuA; high-affinity zinc uptake system protein ZnuA precursor [KO:K09815 ]
NGR_c19790 macB; macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
NGR_c20690 livG; branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
NGR_c20700 livF; predicted branched-chain amino acid transport ATP-binding protein [KO:K01996 ]
NGR_c24150 chvE; multiple sugar-binding periplasmic receptor ChvE precursor [KO:K10546 ]
NGR_c29420 metI; D-methionine transport system permease protein MetI [KO:K02072 ]
NGR_c29840 modA; molybdenum ABC transporter, periplasmic binding protein [KO:K02020 ]
NGR_c36810 ugpC; ABC transporter related sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K05816 ] [EC:7.6.2.10 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway