KEGG   PATHWAY: sir00630
Entry
sir00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Sulfolobus islandicus REY15A
Class
Metabolism; Carbohydrate metabolism
Pathway map
sir00630  Glyoxylate and dicarboxylate metabolism
sir00630

Module
sir_M00012  Glyoxylate cycle [PATH:sir00630]
sir_M00621  Glycine cleavage system [PATH:sir00630]
sir_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sir00630]
Other DBs
GO: 0046487 0043648
Organism
Sulfolobus islandicus REY15A [GN:sir]
Gene
SiRe_0742  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
SiRe_0739  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SiRe_0686  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SiRe_0711  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SiRe_0724  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SiRe_2338  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
SiRe_0033  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SiRe_0741  malate synthase [KO:K01638] [EC:2.3.3.9]
SiRe_2622  Lactate/malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SiRe_2618  2-methylcitrate synthase/citrate synthase II [KO:K01647] [EC:2.3.3.1]
SiRe_1005  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
SiRe_0173  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SiRe_0713  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SiRe_0714  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
SiRe_2328  Thiolase [KO:K00626] [EC:2.3.1.9]
SiRe_2580  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
SiRe_1461  acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) [KO:K00626] [EC:2.3.1.9]
SiRe_2502  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
SiRe_0950  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
SiRe_0215  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
SiRe_0254  Carbamoyl-phosphate synthase L chain ATP-binding protein [KO:K01964] [EC:6.4.1.2 6.4.1.3]
SiRe_0252  carboxyl transferase [KO:K15036] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
SiRe_0253  biotin/lipoyl attachment domain-containing protein [KO:K15037]
SiRe_0075  cobalamin B12-binding domain protein [KO:K01849] [EC:5.4.99.2]
SiRe_0214  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
SiRe_0372  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
SiRe_2089  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
SiRe_1903  SPP-like hydrolase [KO:K22223] [EC:3.1.3.18]
SiRe_1633  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
SiRe_2644  glutamate-ammonia ligase [KO:K01915] [EC:6.3.1.2]
SiRe_0231  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
SiRe_1458  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SiRe_1166  Glycine dehydrogenase (decarboxylating) [KO:K00282] [EC:1.4.4.2]
SiRe_1167  Glycine dehydrogenase (decarboxylating) [KO:K00283] [EC:1.4.4.2]
SiRe_1165  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
SiRe_0979  FAD-dependent pyridine nucleotide-disulfide oxidoreductase [KO:K00382] [EC:1.8.1.4]
SiRe_2640  FAD-dependent pyridine nucleotide-disulphideoxido reductase [KO:K00382] [EC:1.8.1.4]
SiRe_1164  glycine cleavage system H protein [KO:K02437]
SiRe_1032  glycine cleavage H-protein [KO:K02437]
SiRe_0996  glycine cleavage H-protein [KO:K02437]
SiRe_1347  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
SiRe_2464  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
SiRe_1068  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
SiRe_2176  cyclase family protein [KO:K07130] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sir00010  Glycolysis / Gluconeogenesis
sir00020  Citrate cycle (TCA cycle)
sir00030  Pentose phosphate pathway
sir00053  Ascorbate and aldarate metabolism
sir00071  Fatty acid degradation
sir00230  Purine metabolism
sir00250  Alanine, aspartate and glutamate metabolism
sir00260  Glycine, serine and threonine metabolism
sir00620  Pyruvate metabolism
sir00710  Carbon fixation by Calvin cycle
sir00750  Vitamin B6 metabolism
sir00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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