KEGG   PATHWAY: sis00630
Entry
sis00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Sulfolobus islandicus L.S.2.15
Class
Metabolism; Carbohydrate metabolism
Pathway map
sis00630  Glyoxylate and dicarboxylate metabolism
sis00630

Module
sis_M00012  Glyoxylate cycle [PATH:sis00630]
sis_M00621  Glycine cleavage system [PATH:sis00630]
sis_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sis00630]
Other DBs
GO: 0046487 0043648
Organism
Sulfolobus islandicus L.S.2.15 [GN:sis]
Gene
LS215_1004  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
LS215_0753  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
LS215_0033  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
LS215_0802  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
LS215_0991  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
LS215_1000  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
LS215_0923  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
LS215_0941  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
LS215_2617  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
LS215_0798  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
LS215_1003  malate synthase [KO:K01638] [EC:2.3.3.9]
LS215_2892  Lactate/malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
LS215_2888  2-methylcitrate synthase/citrate synthase II [KO:K01647] [EC:2.3.3.1]
LS215_1228  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
LS215_0204  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
LS215_0944  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
LS215_2607  Thiolase [KO:K00626] [EC:2.3.1.9]
LS215_0791  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
LS215_0943  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
LS215_2849  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
LS215_1694  acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (AcaB-1) [KO:K00626] [EC:2.3.1.9]
LS215_2780  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
LS215_1174  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
LS215_0793  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
LS215_0247  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
LS215_0285  Carbamoyl-phosphate synthase L chain ATP-binding [KO:K01964] [EC:6.4.1.2 6.4.1.3]
LS215_0283  carboxyl transferase [KO:K15036] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
LS215_0284  biotin/lipoyl attachment domain-containing protein [KO:K15037]
LS215_0076  cobalamin B12-binding domain protein [KO:K01849] [EC:5.4.99.2]
LS215_0246  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
LS215_2374  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
LS215_2195  SPP-like hydrolase [KO:K22223] [EC:3.1.3.18]
LS215_0263  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
LS215_1877  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
LS215_2914  Glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
LS215_1691  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LS215_1390  Glycine dehydrogenase (decarboxylating) [KO:K00282] [EC:1.4.4.2]
LS215_1391  Glycine dehydrogenase (decarboxylating) [KO:K00283] [EC:1.4.4.2]
LS215_1389  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
LS215_1202  FAD-dependent pyridine nucleotide-disulphide oxidoreductase [KO:K00382] [EC:1.8.1.4]
LS215_0778  FAD-dependent pyridine nucleotide-disulphide oxidoreductase [KO:K00382] [EC:1.8.1.4]
LS215_2910  FAD-dependent pyridine nucleotide-disulphide oxidoreductase [KO:K00382] [EC:1.8.1.4]
LS215_1388  glycine cleavage system H protein [KO:K02437]
LS215_1255  glycine cleavage H-protein [KO:K02437]
LS215_1219  glycine cleavage H-protein [KO:K02437]
LS215_1579  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
LS215_1290  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
LS215_2641  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sis00010  Glycolysis / Gluconeogenesis
sis00020  Citrate cycle (TCA cycle)
sis00030  Pentose phosphate pathway
sis00053  Ascorbate and aldarate metabolism
sis00071  Fatty acid degradation
sis00230  Purine metabolism
sis00250  Alanine, aspartate and glutamate metabolism
sis00260  Glycine, serine and threonine metabolism
sis00620  Pyruvate metabolism
sis00710  Carbon fixation by Calvin cycle
sis00750  Vitamin B6 metabolism
sis00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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