KEGG   PATHWAY: tak00627
Entry
tak00627                    Pathway                                
Name
Aminobenzoate degradation - Thauera aromatica
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
tak00627  Aminobenzoate degradation
tak00627

Other DBs
GO: 0043421
UMBBD: dcz 2,4-d pcp 2,4,5-t box dca
Organism
Thauera aromatica [GN:tak]
Gene
Tharo_1132  benzoate-CoA ligase [KO:K04110] [EC:6.2.1.25]
Tharo_1138  benzoate-CoA ligase [KO:K04110] [EC:6.2.1.25]
Tharo_3014  mandelate dehydrogenase [KO:K15054] [EC:1.1.99.31]
Tharo_0088  FMN-dependent dehydrogenase [KO:K15054] [EC:1.1.99.31]
Tharo_2940  Putative benzaldehyde dehydrogenase [KO:K00141] [EC:1.2.1.28]
Tharo_2908  vanillin dehydrogenase [KO:K00141] [EC:1.2.1.28]
Tharo_1872  3-hydroxy-benzoate-CoA ligase [KO:K20458] [EC:6.2.1.37 6.2.1.27]
Tharo_1515  4-hydroxybenzoyl-CoA reductase, gamma subunit [KO:K04107] [EC:1.1.7.1]
Tharo_1514  4-hydroxybenzoyl-CoA reductase, alpha subunit [KO:K04108] [EC:1.1.7.1]
Tharo_1513  4-hydroxybenzoyl-CoA reductase, beta subunit [KO:K04109] [EC:1.1.7.1]
Tharo_2539  Flavin prenyltransferase UbiX [KO:K03186] [EC:2.5.1.129]
Tharo_2782  3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX [KO:K03186] [EC:2.5.1.129]
Tharo_2779  phenylphosphate carboxylase subunit alpha [KO:K25932] [EC:4.1.1.123]
Tharo_2777  phenylphosphate carboxylase subunit beta [KO:K25933] [EC:4.1.1.123]
Tharo_2780  phenylphosphate carboxylase subunit gamma [KO:K25934] [EC:4.1.1.123]
Tharo_2778  phenylphosphate carboxylase subunit delta [KO:K25935] [EC:4.1.1.123]
Tharo_2774  phenylphosphate synthase subunit A [KO:K25936] [EC:2.7.1.238]
Tharo_2775  phenylphosphate synthase subunit B [KO:K25937] [EC:2.7.1.238]
Tharo_2776  phenylphosphate synthase subunit C [KO:K25938] [EC:2.7.1.238]
Tharo_2558  2-amninobenzoyl-CoA monooxygenase/reductase [KO:K09461] [EC:1.14.13.40]
Tharo_2222  vanillate O-demethylase oxygenase subunit VanA [KO:K03862] [EC:1.14.13.82]
Tharo_2223  vanillate O-demethylase oxidoreductase VanB [KO:K03863]
Tharo_1102  Protocatechuate 4,5-dioxygenase alpha chain PmdA [KO:K04100] [EC:1.13.11.8]
Tharo_1103  Protocatechuate 4,5-dioxygenase beta chain PmdB [KO:K04101] [EC:1.13.11.8]
Tharo_1104  4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase PmdC [KO:K10219] [EC:1.1.1.312]
Tharo_1101  2-pyrone-4,6-dicarboxylic acid hydrolase PmdD [KO:K10221] [EC:3.1.1.57]
Tharo_0611  enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
Tharo_1871  enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
Compound
C00090  Catechol
C00108  Anthranilate
C00146  Phenol
C00156  4-Hydroxybenzoate
C00180  Benzoate
C00196  2,3-Dihydroxybenzoate
C00230  3,4-Dihydroxybenzoate
C00261  Benzaldehyde
C00292  Aniline
C00472  p-Benzoquinone
C00512  Benzoyl-CoA
C00530  Hydroquinone
C00568  4-Aminobenzoate
C00632  3-Hydroxyanthranilate
C00633  4-Hydroxybenzaldehyde
C00755  4-Hydroxy-3-methoxy-benzaldehyde
C00870  4-Nitrophenol
C00877  Crotonoyl-CoA
C01108  1,2,3-Trihydroxybenzene
C01144  (S)-3-Hydroxybutanoyl-CoA
C01424  Gallate
C01502  o-Methoxyphenol
C01983  (R)-Mandelate
C01984  (S)-Mandelate
C01987  2-Aminophenol
C02137  alpha-Oxo-benzeneacetic acid
C02183  Phloroglucinol
C02222  2-Maleylacetate
C02235  4-Nitrocatechol
C02247  Anthraniloyl-CoA
C02372  4-Hydroxyaniline
C02720  Hydroxylaminobenzene
C02734  Phenolic phosphate
C02814  Benzene-1,2,4-triol
C02949  4-Hydroxybenzoyl-CoA
C03198  (S)-4-Hydroxymandelate
C03360  4-Nitrophenyl phosphate
C03590  4-Hydroxyphenylglyoxylate
C03671  2-Pyrone-4,6-dicarboxylate
C03824  2-Aminomuconate semialdehyde
C04434  (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
C04484  4-Carboxy-2-hydroxymuconate semialdehyde
C05165  2-Amino-5-oxocyclohex-1-enecarbonyl-CoA
C05616  3-O-Methylgallate
C06206  Benzoyl phosphate
C06317  Vanillyl alcohol
C06335  4-Aminobenzenesulfonate
C06337  Terephthalate
C06604  Parathion
C06605  Aminoparathion
C06606  Paraoxon
C06607  Diethylthiophosphoric acid
C06608  Diethylphosphoric acid
C06672  Vanillate
C06673  4-Carboxy-4'-sulfoazobenzene
C06674  4-Sulfocatechol
C06675  3-Sulfomuconate
C06676  4-Sulfolactone
C06719  Dihydrophloroglucinol
C06813  Nitrobenzene
C06876  Nitrosobenzene
C07103  2-Hydroxy-1,4-benzoquinone
C07301  (R)-Mandelamide
C08063  1,4-Cyclohexanedione
C09814  Benzonitrile
C09815  Benzamide
C10833  Syringic acid
C14418  3-Nitrophenol
C14602  3-Hydroxyaminophenol
C14604  Aminohydroquinone
C16200  Phenylboronic acid
C16234  o-Nitrobenzoate
C16235  o-Hydroxylaminobenzoate
C16267  Cyclopropanecarboxylate
C16268  Cyclopropanecarboxyl-CoA
C16272  3-Hydroxy-5-oxohexanoate
C16273  3-Hydroxy-5-oxohexanoyl-CoA
C16281  Thiobenzamide
C16283  Thiobenzamide S-oxide
C16285  Thiobenzamide S,S-dioxide
C18338  5-Carboxyvanillic acid
C18345  4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate
C18347  5,5'-Dehydrodivanillate
C18348  2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl
C18349  4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate
C18351  4-Aminocatechol
Reference
PMID:3078743
  Authors
Fewson CA
  Title
Microbial metabolism of mandelate: a microcosm of diversity.
  Journal
FEMS Microbiol Rev 4:85-110 (1988)
DOI:10.1111/j.1574-6968.1988.tb02737.x
Reference
PMID:12670968
  Authors
McLeish MJ, Kneen MM, Gopalakrishna KN, Koo CW, Babbitt PC, Gerlt JA, Kenyon GL
  Title
Identification and characterization of a mandelamide hydrolase and an NAD(P)+-dependent benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633.
  Journal
J Bacteriol 185:2451-6 (2003)
DOI:10.1128/JB.185.8.2451-2456.2003
Reference
PMID:8782397
  Authors
Shimao M, Nakamura T, Okuda A, Harayama S.
  Title
Characteristics of transposon insertion mutants of mandelic acid-utilizing Pseudomonas putida strain A10L.
  Journal
Biosci Biotechnol Biochem 60:1051-5 (1996)
DOI:10.1271/bbb.60.1051
Reference
PMID:11344134
  Authors
Naidu D, Ragsdale SW.
  Title
Characterization of a three-component vanillate O-demethylase from Moorella thermoacetica.
  Journal
J Bacteriol 183:3276-81 (2001)
DOI:10.1128/JB.183.11.3276-3281.2001
Reference
PMID:14711645
  Authors
Toraya T, Oka T, Ando M, Yamanishi M, Nishihara H.
  Title
Novel pathway for utilization of cyclopropanecarboxylate by Rhodococcus rhodochrous.
  Journal
Appl Environ Microbiol 70:224-8 (2004)
DOI:10.1128/AEM.70.1.224-228.2004
Related
pathway
tak00362  Benzoate degradation
tak00380  Tryptophan metabolism
KO pathway
ko00627   
LinkDB

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