KEGG   PATHWAY: tak00630
Entry
tak00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thauera aromatica
Class
Metabolism; Carbohydrate metabolism
Pathway map
tak00630  Glyoxylate and dicarboxylate metabolism
tak00630

Module
tak_M00012  Glyoxylate cycle [PATH:tak00630]
tak_M00621  Glycine cleavage system [PATH:tak00630]
Other DBs
GO: 0046487 0043648
Organism
Thauera aromatica [GN:tak]
Gene
Tharo_2322  Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Tharo_1710  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Tharo_1149  Malate synthase G [KO:K01638] [EC:2.3.3.9]
Tharo_1477  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Tharo_1484  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
Tharo_1471  Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Tharo_1472  Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
Tharo_2947  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tharo_1703  beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
Tharo_1121  beta-ketothiolase [KO:K00626] [EC:2.3.1.9]
Tharo_1157  Acetoacetyl-CoA reductase PhbB1 [KO:K00023] [EC:1.1.1.36]
Tharo_0674  Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Tharo_1156  Acetoacetyl-CoA reductase PhbB2 [KO:K00023] [EC:1.1.1.36]
Tharo_0843  MaoC-like dehydratase [KO:K17865] [EC:4.2.1.55]
Tharo_2792  Propionyl-CoA carboxylase biotin-containing subunit [KO:K01965] [EC:6.4.1.3]
Tharo_2793  Propionyl-CoA carboxylase carboxyl transferase subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Tharo_2795  methylmalonyl-CoA mutase, homodimeric form [KO:K01847] [EC:5.4.99.2]
Tharo_2546  B12 binding domain of heterodimeric CoA mutase IaaG [KO:K01849] [EC:5.4.99.2]
Tharo_2547  heterodimeric methylmalonyl-CoA mutase, large subunit IaaH [KO:K01848] [EC:5.4.99.2]
Tharo_2591  Glycolate dehydrogenase subunit GlcD [KO:K00104] [EC:1.1.99.14]
Tharo_2589  Glycolate dehydrogenase, FAD-binding subunit GlcE [KO:K11472] [EC:1.1.99.14]
Tharo_2588  Glycolate dehydrogenase, iron-sulfur subunit GlcF [KO:K11473] [EC:1.1.99.14]
Tharo_1595  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Tharo_2605  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Tharo_0657  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Tharo_0290  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Tharo_2382  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Tharo_2186  Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) [KO:K00281] [EC:1.4.4.2]
Tharo_2184  glycine cleavage system, aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Tharo_2630  pyruvate dehydrogenase, dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Tharo_1487  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Tharo_2185  glycine cleavage system H protein [KO:K02437]
Tharo_2279  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Tharo_2681  2-hydroxy-3-oxopropionate reductase GarR [KO:K00042] [EC:1.1.1.60]
Tharo_2682  2-hydroxy-3-oxopropionate reductase GlxR [KO:K00042] [EC:1.1.1.60]
Tharo_1148  cytoplasmic molybdopterin oxidoreductase [KO:K00123] [EC:1.17.1.9]
Tharo_0467  formate dehydrogenase large subunit FdhA [KO:K00123] [EC:1.17.1.9]
Tharo_1147  putative NAD(P)H oxidoreductase [KO:K22515] [EC:1.17.1.9]
Tharo_0468  formate dehydrogenase, iron-sulfur subunit FdhB [KO:K00124]
Tharo_0470  formate dehydrogenase, membrane subunit FdhC [KO:K00127]
Tharo_3110  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
tak00010  Glycolysis / Gluconeogenesis
tak00020  Citrate cycle (TCA cycle)
tak00030  Pentose phosphate pathway
tak00071  Fatty acid degradation
tak00230  Purine metabolism
tak00250  Alanine, aspartate and glutamate metabolism
tak00260  Glycine, serine and threonine metabolism
tak00620  Pyruvate metabolism
tak00710  Carbon fixation by Calvin cycle
tak00750  Vitamin B6 metabolism
tak00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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