KEGG   PATHWAY: thar00630
Entry
thar00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thalassobaculum sp. OXR-137
Class
Metabolism; Carbohydrate metabolism
Pathway map
thar00630  Glyoxylate and dicarboxylate metabolism
thar00630

Module
thar_M00012  Glyoxylate cycle [PATH:thar00630]
thar_M00621  Glycine cleavage system [PATH:thar00630]
thar_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:thar00630]
Other DBs
GO: 0046487 0043648
Organism
Thalassobaculum sp. OXR-137 [GN:thar]
Gene
T8K17_03865  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
T8K17_07385  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
T8K17_09065  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
T8K17_12200  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
T8K17_00820  malate synthase G [KO:K01638] [EC:2.3.3.9]
T8K17_04625  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
T8K17_15260  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
T8K17_16605  citrate synthase [KO:K01647] [EC:2.3.3.1]
T8K17_07600  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
T8K17_00765  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
T8K17_02290  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
T8K17_10010  thiolase family protein [KO:K00626] [EC:2.3.1.9]
T8K17_20015  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
T8K17_02295  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
T8K17_05810  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
T8K17_18845  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
T8K17_03760  acyl-CoA dehydrogenase family protein [KO:K14448] [EC:1.3.8.12]
T8K17_24555  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
T8K17_24560  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
T8K17_10855  methylmalonyl-CoA mutase family protein [KO:K01847] [EC:5.4.99.2]
T8K17_10860  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
T8K17_23810  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
T8K17_23805  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
T8K17_23800  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
T8K17_09895  catalase [KO:K03781] [EC:1.11.1.6]
T8K17_03595  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
T8K17_08145  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
T8K17_08150  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
T8K17_24575  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
T8K17_14265  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
T8K17_18290  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
T8K17_22250  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
T8K17_03965  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
T8K17_06565  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
T8K17_10055  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
T8K17_10065  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
T8K17_17100  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
T8K17_22145  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
T8K17_22160  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
T8K17_04150  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
T8K17_18810  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
T8K17_01530  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
T8K17_01520  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
T8K17_04650  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
T8K17_18605  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
T8K17_21075  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
T8K17_01525  gcvH; glycine cleavage system protein GcvH [KO:K02437]
T8K17_10000  glycerate kinase [KO:K11529] [EC:2.7.1.165]
T8K17_02900  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
T8K17_10620  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
T8K17_03840  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
T8K17_20195  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
T8K17_20205  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
T8K17_20210  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region domain-containing protein [KO:K00124]
T8K17_20215  NAD(P)H-dependent oxidoreductase subunit E [KO:K00127]
T8K17_04810  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
thar00010  Glycolysis / Gluconeogenesis
thar00020  Citrate cycle (TCA cycle)
thar00030  Pentose phosphate pathway
thar00053  Ascorbate and aldarate metabolism
thar00071  Fatty acid degradation
thar00230  Purine metabolism
thar00250  Alanine, aspartate and glutamate metabolism
thar00260  Glycine, serine and threonine metabolism
thar00620  Pyruvate metabolism
thar00710  Carbon fixation by Calvin cycle
thar00750  Vitamin B6 metabolism
thar00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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