KEGG   PATHWAY: thau00630
Entry
thau00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thauera humireducens Piv1
Class
Metabolism; Carbohydrate metabolism
Pathway map
thau00630  Glyoxylate and dicarboxylate metabolism
thau00630

Module
thau_M00012  Glyoxylate cycle [PATH:thau00630]
thau_M00621  Glycine cleavage system [PATH:thau00630]
Other DBs
GO: 0046487 0043648
Organism
Thauera humireducens Piv1 [GN:thau]
Gene
C4PIVTH_0317  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
C4PIVTH_3460  acs; acetyl-CoA synthetase (AMP-forming) [KO:K01895] [EC:6.2.1.1]
C4PIVTH_4364  4-hydroxybutyrate--CoA ligase 1 [KO:K01895] [EC:6.2.1.1]
C4PIVTH_0398  protein of unknown function [KO:K01895] [EC:6.2.1.1]
C4PIVTH_0417  4-hydroxybutyrate--CoA ligase 1 [KO:K01895] [EC:6.2.1.1]
C4PIVTH_4136  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
C4PIVTH_3337  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
C4PIVTH_3344  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
C4PIVTH_3323  acnB; Aconitate hydratase B [KO:K01682] [EC:4.2.1.3 4.2.1.99]
C4PIVTH_3454  bktB; Beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
C4PIVTH_4181  fadA; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
C4PIVTH_4224  fadA; Steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
C4PIVTH_0751  pcaF; Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
C4PIVTH_0889  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
C4PIVTH_0202  fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG [KO:K00023] [EC:1.1.1.36]
C4PIVTH_0203  fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG [KO:K00023] [EC:1.1.1.36]
C4PIVTH_2251  phaJ; (R)-specific enoyl-CoA hydratase [KO:K17865] [EC:4.2.1.55]
C4PIVTH_1950  pccA; Propionyl-CoA carboxylase alpha chain [KO:K01965] [EC:6.4.1.3]
C4PIVTH_1949  pccB; Propionyl-CoA carboxylase beta chain [KO:K01966] [EC:6.4.1.3 2.1.3.15]
C4PIVTH_1947  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
C4PIVTH_3583  glcD; glycolate dehydrogenase, putative FAD-linked subunit [KO:K00104] [EC:1.1.99.14]
C4PIVTH_3584  glcE; glycolate dehydrogenase, putative FAD-binding subunit [KO:K11472] [EC:1.1.99.14]
C4PIVTH_3585  glcF; glycolate dehydrogenase, putative iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
C4PIVTH_1008  hprA; Glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
C4PIVTH_3969  putative phosphoglycolate phosphatase, clustered with ribosomal large subunit pseudouridine synthase C [KO:K01091] [EC:3.1.3.18]
C4PIVTH_0574  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
C4PIVTH_1875  Haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
C4PIVTH_2378  cbbL; Ribulose bisphosphate carboxylase large chain [KO:K01601] [EC:4.1.1.39]
C4PIVTH_2377  cbbS; Ribulose bisphosphate carboxylase small chain [KO:K01602] [EC:4.1.1.39]
C4PIVTH_1831  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
C4PIVTH_2425  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C4PIVTH_4075  gcvP; glycine decarboxylase [KO:K00281] [EC:1.4.4.2]
C4PIVTH_4073  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
C4PIVTH_2624  Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
C4PIVTH_3347  odhL; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C4PIVTH_0030  lpd; lipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
C4PIVTH_4074  gcvH; glycine cleavage system H protein [KO:K02437]
C4PIVTH_4212  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
C4PIVTH_4213  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
C4PIVTH_4214  glxR; tartronate semialdehyde reductase 2 [KO:K00042] [EC:1.1.1.60]
C4PIVTH_1358  glxR; tartronate semialdehyde reductase 2 [KO:K00042] [EC:1.1.1.60]
C4PIVTH_2041  glxR; tartronate semialdehyde reductase 2 [KO:K00042] [EC:1.1.1.60]
C4PIVTH_2042  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
C4PIVTH_1349  garK; glycerate 2-kinase 1 [KO:K00865] [EC:2.7.1.165]
C4PIVTH_4216  ttuD; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
C4PIVTH_2723  dmlA; D-malate/3-isopropylmalate dehydrogenase (decarboxylating) [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
C4PIVTH_1097  NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
C4PIVTH_4137  tungsten-containing formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
C4PIVTH_1095  NAD-dependent formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
C4PIVTH_1760  Formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
C4PIVTH_4138  tungsten-containing formate dehydrogenase beta subunit [KO:K22515] [EC:1.17.1.9]
C4PIVTH_1094  NAD-dependent formate dehydrogenase beta subunit [KO:K00124]
C4PIVTH_1761  fdhB; Formate dehydrogenase iron-sulfur subunit [KO:K00124]
C4PIVTH_1093  NAD-dependent formate dehydrogenase gamma subunit [KO:K00127]
C4PIVTH_1763  Formate dehydrogenase subunit gamma [KO:K00127]
C4PIVTH_1074  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
C4PIVTH_0991  fmdA; Formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
thau00010  Glycolysis / Gluconeogenesis
thau00020  Citrate cycle (TCA cycle)
thau00030  Pentose phosphate pathway
thau00053  Ascorbate and aldarate metabolism
thau00071  Fatty acid degradation
thau00230  Purine metabolism
thau00250  Alanine, aspartate and glutamate metabolism
thau00260  Glycine, serine and threonine metabolism
thau00620  Pyruvate metabolism
thau00710  Carbon fixation by Calvin cycle
thau00750  Vitamin B6 metabolism
thau00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system