KEGG   PATHWAY: tim00630
Entry
tim00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Tuwongella immobilis
Class
Metabolism; Carbohydrate metabolism
Pathway map
tim00630  Glyoxylate and dicarboxylate metabolism
tim00630

Module
tim_M00621  Glycine cleavage system [PATH:tim00630]
Other DBs
GO: 0046487 0043648
Organism
Tuwongella immobilis [GN:tim]
Gene
GMBLW1_39510  3-hydroxypropionyl-synthetase : Acetyl-coenzyme A synthetase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=acsA PE=3 SV=1: AMP-binding: AMP-binding_C [KO:K01895] [EC:6.2.1.1]
GMBLW1_19910  malate dehydrogenase : Malate dehydrogenase OS=Coxiella burnetii str. Namibia GN=mdh PE=3 SV=1: Ldh_1_N: Ldh_1_C [KO:K00024] [EC:1.1.1.37]
GMBLW1_06510  citrate synthase : Citrate synthase OS=Gloeocapsa sp. PCC 7428 GN=Glo7428_1192 PE=3 SV=1: Citrate_synt [KO:K01647] [EC:2.3.3.1]
GMBLW1_15310  aconitate hydratase : Aconitate hydratase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_6551 PE=3 SV=1: Aconitase: Aconitase_C [KO:K01681] [EC:4.2.1.3]
GMBLW1_02750  family dehydratase : Acyl dehydratase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_1850 PE=4 SV=1: MaoC_dehydratas [KO:K17865] [EC:4.2.1.55]
GMBLW1_12010  glycolate oxidase subunit : FAD linked oxidase domain protein OS=Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) GN=Psta_2649 PE=4 SV=1: FAD_binding_4: FAD-oxidase_C [KO:K00104] [EC:1.1.99.14]
GMBLW1_12020  fad linked oxidase domain protein : FAD/FMN-dependent dehydrogenase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_1446 PE=4 SV=1: FAD_binding_4: FAD-oxidase_C [KO:K11472] [EC:1.1.99.14]
GMBLW1_12030  glycolate oxidase : Uncharacterized protein OS=Planctomyces maris DSM 8797 GN=PM8797T_00377 PE=4 SV=1: Fer4_8: CCG: CCG [KO:K11473] [EC:1.1.99.14]
GMBLW1_41330  catalase : Probable catalase hydroperoxidase hpii oxidoreductase protein OS=Blastopirellula marina DSM 3645 GN=DSM3645_04750 PE=4 SV=1: Catalase: Catalase-rel [KO:K03781] [EC:1.11.1.6]
GMBLW1_22040  glyoxylate reductase : Glycerate dehydrogenase OS=Rhodopirellula baltica WH47 GN=RBWH47_01949 PE=3 SV=1: 2-Hacid_dh: 2-Hacid_dh_C [KO:K00015] [EC:1.1.1.26]
GMBLW1_37710  Haloacid dehalogenase domain protein hydrolase OS=Chthoniobacter flavus Ellin428 GN=CfE428DRAFT_2435 PE=4 SV=1: Hydrolase_like [KO:K01091] [EC:3.1.3.18]
GMBLW1_34490  phosphoglycolate phosphatase : HAD-superfamily hydrolase OS=Thermoanaerobacter thermohydrosulfuricus WC1 GN=TthWC1_1184 PE=4 SV=1: HAD_2 [KO:K01091] [EC:3.1.3.18]
GMBLW1_44760  alanine--glyoxylate aminotransferase : Aminotransferase class V OS=Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) GN=Psta_2949 PE=3 SV=1: Aminotran_5 [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
GMBLW1_42690  glutamate synthase : Glutamate synthase OS=Clostridium acetobutylicum GN=NL50_00220 PE=4 SV=1: GATase_2: Glu_syn_central: Glu_synthase: GXGXG [KO:K00284] [EC:1.4.7.1]
GMBLW1_03090  glutamine synthetase : Glutamine synthetase OS=Blastopirellula marina DSM 3645 GN=DSM3645_13233 PE=3 SV=1: Gln-synt_N: Gln-synt_C [KO:K01915] [EC:6.3.1.2]
GMBLW1_03100  glutamine synthetase : Glutamine synthetase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_4895 PE=3 SV=1: GSIII_N: Gln-synt_C [KO:K01915] [EC:6.3.1.2]
GMBLW1_27270  serine hydroxymethyltransferase : Serine hydroxymethyltransferase OS=Planctomyces limnophilus (strain ATCC 43296 / DSM 3776 / IFAM 1008 / 290) GN=glyA PE=3 SV=1: SHMT [KO:K00600] [EC:2.1.2.1]
GMBLW1_16080  glycine dehydrogenase subunit 1 : Probable glycine dehydrogenase (decarboxylating) subunit 1 OS=Blastopirellula marina DSM 3645 GN=gcvPA PE=3 SV=1: GDC-P [KO:K00282] [EC:1.4.4.2]
GMBLW1_16060  glycine dehydrogenase subunit 2 : Probable glycine dehydrogenase (decarboxylating) subunit 2 OS=uncultured planctomycete GN=gcvPB PE=3 SV=1: GDC-P [KO:K00283] [EC:1.4.4.2]
GMBLW1_16100  glycine cleavage system protein t : Aminomethyltransferase OS=Planctomyces maris DSM 8797 GN=gcvT PE=3 SV=1: GCV_T: GCV_T_C [KO:K00605] [EC:2.1.2.10]
GMBLW1_45090  dihydrolipoamide dehydrogenase : Dihydrolipoyl dehydrogenase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_6538 PE=3 SV=1: Pyr_redox_2: Pyr_redox: Pyr_redox_dim [KO:K00382] [EC:1.8.1.4]
GMBLW1_06560  dihydrolipoamide dehydrogenase : Dihydrolipoyl dehydrogenase OS=Planctomyces brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) GN=Plabr_4534 PE=3 SV=1: Pyr_redox_2: Pyr_redox: Pyr_redox_dim [KO:K00382] [EC:1.8.1.4]
GMBLW1_38970  unnamed protein product; BLAST_uniprot: no_hits [KO:K02437]
GMBLW1_45230  Glycine cleavage H-protein OS=Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) GN=Psta_4504 PE=4 SV=1: GCV_H [KO:K02437]
GMBLW1_16090  glycine cleavage system protein h : Glycine cleavage system H protein OS=Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B) GN=gcvH PE=3 SV=1: GCV_H [KO:K02437]
GMBLW1_13580  Hydroxypyruvate isomerase OS=Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B) GN=Isop_2183 PE=4 SV=1: AP_endonuc_2 [KO:K01816] [EC:5.3.1.22]
GMBLW1_07170  glycerate kinase : Putative uncharacterized protein OS=uncultured Desulfobacterium sp. GN=N47_E46250 PE=4 SV=1: DUF4147: MOFRL [KO:K11529] [EC:2.7.1.165]
GMBLW1_35020  tartrate dehydrogenase : 3-isopropylmalate dehydrogenase OS=Solibacter usitatus (strain Ellin6076) GN=Acid_1530 PE=3 SV=1: Iso_dh [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
GMBLW1_20740  2-dehydro-3-deoxyphosphogluconate aldolase : Entner-Doudoroff aldolase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_1080 PE=4 SV=1: Aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
tim00010  Glycolysis / Gluconeogenesis
tim00020  Citrate cycle (TCA cycle)
tim00030  Pentose phosphate pathway
tim00053  Ascorbate and aldarate metabolism
tim00071  Fatty acid degradation
tim00230  Purine metabolism
tim00250  Alanine, aspartate and glutamate metabolism
tim00260  Glycine, serine and threonine metabolism
tim00620  Pyruvate metabolism
tim00710  Carbon fixation by Calvin cycle
tim00750  Vitamin B6 metabolism
tim00910  Nitrogen metabolism
KO pathway
ko00630   
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