KEGG   PATHWAY: tml04148
Entry
tml04148                    Pathway                                
Name
Efferocytosis - Tuber melanosporum
Class
Cellular Processes; Transport and catabolism
Pathway map
tml04148  Efferocytosis
tml04148

Organism
Tuber melanosporum [GN:tml]
Gene
GSTUM_00000551001  hypothetical protein [KO:K04371] [EC:2.7.11.24]
GSTUM_00005852001  hypothetical protein [KO:K04441] [EC:2.7.11.24]
GSTUM_00010734001  hypothetical protein [KO:K04459] [EC:3.1.3.16 3.1.3.48]
GSTUM_00002118001  hypothetical protein [KO:K14802] [EC:7.6.2.1]
GSTUM_00006251001  hypothetical protein [KO:K26935]
GSTUM_00007688001  hypothetical protein [KO:K26935]
GSTUM_00010651001  hypothetical protein [KO:K12366]
GSTUM_00003067001  hypothetical protein [KO:K04392]
GSTUM_00002629001  hypothetical protein [KO:K07889]
GSTUM_00005657001  hypothetical protein [KO:K07889]
GSTUM_00005339001  hypothetical protein [KO:K20177]
GSTUM_00008840001  hypothetical protein [KO:K20178]
GSTUM_00006343001  hypothetical protein [KO:K20179]
GSTUM_00005365001  hypothetical protein [KO:K20180]
GSTUM_00006080001  hypothetical protein [KO:K20181]
GSTUM_00011246001  hypothetical protein [KO:K20182]
GSTUM_00007760001  hypothetical protein [KO:K20183]
GSTUM_00008038001  hypothetical protein [KO:K20184]
GSTUM_00005408001  hypothetical protein [KO:K07897]
GSTUM_00007719001  hypothetical protein [KO:K07897]
GSTUM_00011683001  hypothetical protein [KO:K23678]
GSTUM_00007380001  hypothetical protein [KO:K23678]
GSTUM_00003917001  hypothetical protein [KO:K23678]
GSTUM_00003192001  hypothetical protein [KO:K01476] [EC:3.5.3.1]
GSTUM_00011982001  hypothetical protein [KO:K01581] [EC:4.1.1.17]
GSTUM_00004969001  hypothetical protein [KO:K01052] [EC:3.1.1.13]
Compound
C00002  ATP
C00003  NAD+
C00019  S-Adenosyl-L-methionine
C00031  D-Glucose
C00062  L-Arginine
C00073  L-Methionine
C00075  UTP
C00077  L-Ornithine
C00134  Putrescine
C00162  Fatty acid
C00186  (S)-Lactate
C00187  Cholesterol
C00584  Prostaglandin E2
C02530  Cholesterol ester
C02737  Phosphatidylserine
C04230  1-Acyl-sn-glycero-3-phosphocholine
C06124  Sphingosine 1-phosphate
C06314  Lipoxin A4
C15519  25-Hydroxycholesterol
C15610  Cholest-5-ene-3beta,26-diol
C18178  Resolvin D1
Reference
PMID:31822793
  Authors
Doran AC, Yurdagul A Jr, Tabas I
  Title
Efferocytosis in health and disease.
  Journal
Nat Rev Immunol 20:254-267 (2020)
DOI:10.1038/s41577-019-0240-6
Reference
PMID:36028471
  Authors
Zhang J, Ding W, Zhao M, Liu J, Xu Y, Wan J, Wang M
  Title
Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease.
  Journal
Br J Pharmacol 179:5151-5171 (2022)
DOI:10.1111/bph.15939
Reference
PMID:30165442
  Authors
Kawano M, Nagata S
  Title
Efferocytosis and autoimmune disease.
  Journal
Int Immunol 30:551-558 (2018)
DOI:10.1093/intimm/dxy055
Reference
PMID:35650427
  Authors
Mehrotra P, Ravichandran KS
  Title
Drugging the efferocytosis process: concepts and opportunities.
  Journal
Nat Rev Drug Discov 21:601-620 (2022)
DOI:10.1038/s41573-022-00470-y
Reference
PMID:28496201
  Authors
Park SY, Kim IS
  Title
Engulfment signals and the phagocytic machinery for apoptotic cell clearance.
  Journal
Exp Mol Med 49:e331 (2017)
DOI:10.1038/emm.2017.52
Reference
PMID:28137963
  Authors
Kojima Y, Weissman IL, Leeper NJ
  Title
The Role of Efferocytosis in Atherosclerosis.
  Journal
Circulation 135:476-489 (2017)
DOI:10.1161/CIRCULATIONAHA.116.025684
Related
pathway
tml00010  Glycolysis / Gluconeogenesis
tml04145  Phagosome
KO pathway
ko04148   
LinkDB

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