PATHWAY: vcm02010 Help
Entry Name ABC transporters - Vibrio cholerae O1 M66-2
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Vibrio cholerae O1 M66-2 [GN:
vcm ]
Gene VCM66_0496 cysP; thiosulfate ABC transporter, periplasmic thiosulfate-binding protein [KO:K02048 ]
VCM66_A0684 modA; molybdenum ABC transporter, periplasmic molybdenum-binding protein [KO:K02020 ]
VCM66_0566 fbpA; iron(III) ABC transporter, periplasmic iron-compound-binding protein [KO:K02012 ]
VCM66_A0643 iron(III) ABC transporter, periplasmic iron-compound-binding protein [KO:K02012 ]
VCM66_2460 tbpA; thiamin ABC transporter, periplasmic thiamin-binding protein [KO:K02064 ]
VCM66_1380 potD-1; spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein [KO:K11069 ]
VCM66_1381 potD-2; spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein [KO:K11069 ]
VCM66_0662 putative spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein [KO:K11069 ]
VCM66_A1069 spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein [KO:K11069 ]
VCM66_1382 potC; spermidine/putrescine ABC transporter, permease protein [KO:K11070 ]
VCM66_1383 potB; spermidine/putrescine ABC transporter, permease protein [KO:K11071 ]
VCM66_A0905 malE; maltose ABC transporter, periplasmic maltose-binding protein [KO:K10108 ]
VCM66_A0906 malK; maltose/maltodextrin ABC transporter, ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
VCM66_A0128 rbsB; ribose ABC transporter, periplasmic D-ribose-binding protein [KO:K10439 ]
VCM66_1280 mglB; galactoside ABC transporter, periplasmic D-galactose/D-glucose-binding protein [KO:K10540 ]
VCM66_1490 ugpB; glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein [KO:K05813 ]
VCM66_1491 ugpA; glycerol-3-phosphate ABC transporter, permease protein [KO:K05814 ]
VCM66_1492 ugpE; glycerol-3-phosphate ABC transporter, permease protein [KO:K05815 ]
VCM66_A0067 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein [KO:K02040 ]
VCM66_0679 putative phosphate ABC transporter, periplasmic phosphate-binding protein [KO:K02040 ]
VCM66_A0718 artI; arginine ABC transporter, periplasmic arginine-binding protein [KO:K09997 ]
VCM66_1317 amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K09969 ]
VCM66_0010 amino acid ABC transporter, periplasmic amino acid-binding portion [KO:K16961 ]
VCM66_1786 amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K10022 ]
VCM66_1047 oppA; oligopeptide ABC transporter, periplasmic oligopeptide-binding protein [KO:K15580 ]
VCM66_1620 sapA; peptide ABC transporter, periplasmic peptide-binding protein [KO:K19226 ]
VCM66_A0550 putative peptide ABC transporter, periplasmic peptide-binding protein [KO:K13893 ]
VCM66_0734 viuP; vibriobactin and enterobactin ABC transporter, periplasmic ferric vibriobactin/enterobactin-binding protein [KO:K23185 ]
VCM66_0735 viuD; vibriobactin and enterobactin ABC transporter, permease protein [KO:K23186 ]
VCM66_0736 viuG; vibriobactin and enterobactin ABC transporter, permease protein [KO:K23187 ]
VCM66_0190 fhuC; iron(III) ABC transporter, periplasmic iron-compound-binding protein [KO:K23227 ]
VCM66_2005 znuA; zinc ABC transporter, periplasmic zinc-binding protein [KO:K09815 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
