KEGG   PATHWAY: vni02020
Entry
vni02020                    Pathway                                
Name
Two-component system - Vibrio nigripulchritudo
Description
Two-component signal transduction systems enable bacteria to sense, respond, and adapt to changes in their environment or in their intracellular state. Each two-component system consists of a sensor protein-histidine kinase (HK) and a response regulator (RR). In the prototypical two-component pathway, the sensor HK phosphorylates its own conserved His residue in response to a signal(s) in the environment. Subsequently, the phosphoryl group of HK is transferred onto a specific Asp residue on the RR. The activated RR can then effect changes in cellular physiology, often by regulating gene expression. Two-component pathways thus often enable cells to sense and respond to stimuli by inducing changes in transcription.
Class
Environmental Information Processing; Signal transduction
Pathway map
vni02020  Two-component system
vni02020

Other DBs
GO: 0000160
Organism
Vibrio nigripulchritudo [GN:vni]
Gene
VIBNI_A0406  phoR; Phosphate regulon sensor protein phoR [KO:K07636] [EC:2.7.13.3]
VIBNI_A0405  phoB; Phosphate regulon transcriptional regulatory protein phoB [KO:K07657]
VIBNI_A3590  Akp; Embryonic alkaline phosphatase [KO:K01077] [EC:3.1.3.1]
VIBNI_A0407  pstS; Phosphate ABC transporter, periplasmic phosphate-binding protein, PstS [KO:K02040]
VIBNI_B0212  putative ABC-type phosphate transport system, periplasmic component [KO:K02040]
VIBNI_B0958  pstS; Periplasmic phosphate binding protein [KO:K02040]
VIBNI_A3300  putative Permease of the drug/metabolite transporter (DMT) superfamily [KO:K07790]
VIBNI_A3722  envZ; Osmolarity sensor protein envZ [KO:K07638] [EC:2.7.13.3]
VIBNI_A3723  ompR; Transcriptional regulatory protein ompR [KO:K07659]
VIBNI_A3258  cpxA; Sensor protein cpxA [KO:K07640] [EC:2.7.13.3]
VIBNI_A3257  cpxR; Transcriptional regulatory protein cpxR [KO:K07662]
VIBNI_A0837  putative SENSORY TRANSDUCTION HISTIDINE KINASE [KO:K07639] [EC:2.7.13.3]
VIBNI_B0196  putative TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE REGULATOR [KO:K07661]
VIBNI_A0204  degP; Protease do [KO:K04771] [EC:3.4.21.107]
VIBNI_B0179  creC; Sensor protein creC [KO:K07641] [EC:2.7.13.3]
VIBNI_B0180  blrA; Beta-lactamase response regulator [KO:K07663]
VIBNI_B0242  putative copper/silver efflux system membrane fusion protein [KO:K07798]
VIBNI_B0243  cusA; copper/silver efflux system, membrane component [KO:K07787]
VIBNI_A2630  flaA; Flagellin A [KO:K02406]
VIBNI_A0704  flaF; Polar flagellin F [KO:K02406]
VIBNI_A0707  flaD; Polar flagellin B/D [KO:K02406]
VIBNI_A0708  flaD; Polar flagellin B/D [KO:K02406]
VIBNI_A0709  flaD; Polar flagellin B/D [KO:K02406]
VIBNI_A0710  flaC; Flagellin C [KO:K02406]
VIBNI_A0712  flaD; Flagellin D [KO:K02406]
VIBNI_A0713  flaA; Polar flagellin A [KO:K02406]
VIBNI_A0741  fliA; RNA polymerase sigma factor for flagellar operon [KO:K02405]
VIBNI_A0577  putative Flagellar motor rotation protein MotA [KO:K02556]
VIBNI_A0666  pomA; Chemotaxis protein pomA [KO:K02556]
VIBNI_B1244  putative TMAO reductase sytem sensor TorS [KO:K07647] [EC:2.7.13.3]
VIBNI_A2110  torR; TorCAD operon transcriptional regulatory protein torR [KO:K07772]
VIBNI_A1329  putative Pentahemic c-type cytochrome [KO:K03532]
VIBNI_A1330  torA; Trimethylamine-N-oxide reductase precursor (TMAO reductase) (Trimethylamine oxidase) [KO:K07811] [EC:1.7.2.3]
VIBNI_A2112  torD; Chaperone protein torD [KO:K03533]
VIBNI_A0282  arcB; Aerobic respiration control sensor protein arcB [KO:K07648] [EC:2.7.13.3]
VIBNI_A0284  arcA; Aerobic respiration control protein arcA [KO:K07773]
VIBNI_B1910  conserved hypothetical protein [KO:K07793]
VIBNI_B0843  putative Tripartite tricarboxylate transporter TctA family [KO:K07793]
VIBNI_B1985  conserved hypothetical protein [KO:K07793]
VIBNI_A1836  putative Tricarboxylate transport membrane protein TctA [KO:K07793]
VIBNI_B1909  hypothetical protein [KO:K07794]
VIBNI_A1835  putative tricarboxylic transport TctB [KO:K07794]
VIBNI_B1984  conserved hypothetical protein [KO:K07794]
VIBNI_B0844  hypothetical protein [KO:K07794]
VIBNI_A1834  Putative tricarboxylic transport TctC [KO:K07795]
VIBNI_B1983  putative Bordetella uptake gene (bug) product [KO:K07795]
VIBNI_B0845  putative Bordetella uptake gene [KO:K07795]
VIBNI_B1649  putative Cytochrome oxidase assembly protein (COX15-CtaA) [KO:K02259] [EC:1.17.99.9]
VIBNI_A0001  dnaA; Chromosomal replication initiator protein dnaA [KO:K02313]
VIBNI_A3719  putative ANTIBIOTIC SYNTHETASE [KO:K03367] [EC:6.1.1.13]
VIBNI_B0886  putative Signal transduction histidine kinase [KO:K19609] [EC:2.7.13.3]
VIBNI_B0885  putative TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE REGULATOR [KO:K19610]
VIBNI_B1812  putative Lantibiotic dehydratase [KO:K20483]
VIBNI_B1813  putative Lanthionine synthetase C-like [KO:K20484]
VIBNI_A1146  sfcA; NAD-dependent malic enzyme [KO:K00027] [EC:1.1.1.38]
VIBNI_A2464  putative Signal transduction response regulator [KO:K07684]
VIBNI_A1857  putative Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [KO:K07684]
VIBNI_A2015  putative Transcription regulator LuxR [KO:K07684]
VIBNI_B1298  putative nitrate/nitrite sensor protein NarQ [KO:K07674] [EC:2.7.13.3]
VIBNI_B1297  narP; Nitrate/nitrite response regulator protein narP [KO:K07685]
VIBNI_A3236  frdA; Fumarate reductase flavoprotein subunit [KO:K00244] [EC:1.3.5.1]
VIBNI_A3237  frdB; Fumarate reductase iron-sulfur subunit [KO:K00245] [EC:1.3.5.1]
VIBNI_A3238  frdC; Fumarate reductase subunit C [KO:K00246]
VIBNI_A3239  frdD; Fumarate reductase subunit D [KO:K00247]
VIBNI_B1115  putative GLYCEROL-3-PHOSPHATE TRANSPORTER (HEXOSE TRANSPORTER) [KO:K07783]
VIBNI_A0122  barA; Signal transduction histidine-protein kinase barA [KO:K07678] [EC:2.7.13.3]
VIBNI_A1306  uvrY; Response regulator uvrY [KO:K07689]
VIBNI_A0151  csrA; Carbon storage regulator [KO:K03563]
VIBNI_A2043  putative Signal transduction histidine kinase, nitrogen specific with PBPb domain [KO:K07679] [EC:2.7.13.3]
VIBNI_B1741  putative Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [KO:K07690]
VIBNI_A0533  putative P pilus assembly protein, chaperone PapD [KO:K07346]
VIBNI_B0680  putative Flp/Fap pilin component [KO:K02651]
VIBNI_A3435  putative Flp pilus assembly protein, pilin Flp [KO:K02651]
VIBNI_A0514  putative Flp/Fap pilin component [KO:K02651]
VIBNI_A1925  putative Flp/Fap pilin component [KO:K02651]
VIBNI_B0681  putative Pilus assembly, Flp-type CpaB [KO:K02279]
VIBNI_A3433  putative Flp pilus assembly protein CpaB [KO:K02279]
VIBNI_B0682  putative Flp pilus assembly protein, secretin CpaC [KO:K02280]
VIBNI_A3432  putative Flp pilus assembly protein, secretin CpaC [KO:K02280]
VIBNI_A1923  putative Flp pilus assembly protein, secretin CpaC [KO:K02280]
VIBNI_B0684  putative ATPase [KO:K02282]
VIBNI_A3430  putative Flp pilus assembly protein, ATPase CpaE [KO:K02282]
VIBNI_A1921  putative ATPase [KO:K02282]
VIBNI_B0685  putative Flp pilus assembly protein, ATPase CpaF [KO:K02283] [EC:7.4.2.8]
VIBNI_A3429  putative Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily [KO:K02283] [EC:7.4.2.8]
VIBNI_A1920  putative Flp pilus assembly protein, ATPase CpaF [KO:K02283] [EC:7.4.2.8]
VIBNI_B0686  conserved hypothetical protein [KO:K12510]
VIBNI_A3428  putative Flp pilus assembly protein TadB [KO:K12510]
VIBNI_A1919  conserved hypothetical protein [KO:K12510]
VIBNI_B0687  putative Flp pilus assembly protein TadC [KO:K12511]
VIBNI_A3427  putative Flp pilus assembly protein TadC [KO:K12511]
VIBNI_A1918  putative Flp pilus assembly protein TadC [KO:K12511]
VIBNI_A2506  glnD; [Protein-PII] uridylyltransferase [KO:K00990] [EC:2.7.7.59]
VIBNI_A2484  glnB; Nitrogen regulatory protein P-II 1 [KO:K04751]
VIBNI_A3480  glnL; Nitrogen regulation protein NR(II) [KO:K07708] [EC:2.7.13.3]
VIBNI_A3481  glnG; Nitrogen regulation protein NR(I) [KO:K07712]
VIBNI_A1348  putative Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
VIBNI_A3478  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
VIBNI_B0464  ctfA; Butyrate--acetoacetate CoA-transferase subunit A [KO:K01034] [EC:2.8.3.8 2.8.3.9]
VIBNI_B0463  ctfB; Butyrate--acetoacetate CoA-transferase subunit B [KO:K01035] [EC:2.8.3.8 2.8.3.9]
VIBNI_B0465  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
VIBNI_A1234  phbA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
VIBNI_B1306  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
VIBNI_B1113  putative ABC-type Fe3+ transport system, periplasmic component [KO:K08478]
VIBNI_B1112  putative TWO COMPONENT HISTIDINE KINASE [KO:K08475] [EC:2.7.13.3]
VIBNI_A3282  putative Signal transduction histidine kinase [KO:K08475] [EC:2.7.13.3]
VIBNI_B1111  putative Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [KO:K08476]
VIBNI_B1172  putative TWO COMPONENT HISTIDINE KINASE [KO:K10125] [EC:2.7.13.3]
VIBNI_A2430  putative Signal transduction histidine kinase regulating C4-dicarboxylate transport system [KO:K10125] [EC:2.7.13.3]
VIBNI_B1173  putative AtoC, Response regulator [KO:K10126]
VIBNI_A2431  dctD; C4-dicarboxylate transport transcriptional regulatory protein dctD [KO:K10126]
VIBNI_A3283  dctD; C4-dicarboxylate transport transcriptional regulatory protein dctD [KO:K10126]
VIBNI_B1504  dctD; C4-dicarboxylate transport transcriptional regulatory protein dctD [KO:K10126]
VIBNI_A2951  rpoN; RNA polymerase, sigma 54 (sigma N) factor [KO:K03092]
VIBNI_A2643  cheR; Chemotaxis protein methyltransferase [KO:K00575] [EC:2.1.1.80]
VIBNI_B0012  putative Protein-glutamate O-methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
VIBNI_A0193  putative methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A0043  putative methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B0830  putative Methyl-accepting chemotaxis protein (MCP) fused with PAS/PAC domain [KO:K03406]
VIBNI_B1082  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1387  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A0944  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1048  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1059  putative methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1094  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1304  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1338  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1371  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1469  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1665  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1813  Putative methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A1709  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A2007  putative Metal dependent phosphohydrolase fused with Methyl-accepting protein [KO:K03406]
VIBNI_A2046  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A2138  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A2142  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A2671  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A2451  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B0011  putative Methyl-accepting chemotaxis protein (MCP) fused with PAS/PAC domain [KO:K03406]
VIBNI_B0016  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1028  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_A3309  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1351  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1497  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1509  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1528  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1558  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1635  putative methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1647  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1778  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B1861  putative Methyl-accepting chemotaxis protein [KO:K03406]
VIBNI_B0171  putative Chemotaxis methyl-accepting receptor [KO:K03776]
VIBNI_A1574  putative Aerotaxis sensor receptor protein [KO:K03776]
VIBNI_A0748  putative Methyl-accepting chemotaxis protein [KO:K03408]
VIBNI_A0749  cheW; Chemotaxis protein CheW [KO:K03408]
VIBNI_B0009  cheW; Chemotaxis protein cheW [KO:K03408]
VIBNI_B0010  cheW; Chemotaxis protein cheW [KO:K03408]
VIBNI_B0008  cheA; Chemotaxis protein cheA [KO:K03407] [EC:2.7.13.3]
VIBNI_A0745  cheA; Chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
VIBNI_B0007  cheY; Chemotaxis protein cheY [KO:K03413]
VIBNI_A1055  putative TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE REGULATOR [KO:K03413]
VIBNI_A0743  cheY; Chemotaxis protein cheY [KO:K03413]
VIBNI_B0014  cheB; Chemotaxis response regulator protein-glutamate methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
VIBNI_A0746  cheB; Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon [KO:K03412] [EC:3.1.1.61 3.5.1.44]
VIBNI_B0862  putative chemotaxis protein CheV [KO:K03415]
VIBNI_A2338  putative CheY/CheW-like protein [KO:K03415]
VIBNI_A2644  putative CheY/CheW hybrid protein CheV [KO:K03415]
VIBNI_A1049  putative TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE REGULATOR [KO:K03415]
VIBNI_B1296  luxP; Autoinducer 2-binding periplasmic protein luxP [KO:K10910]
VIBNI_A1884  putative Autoinducer 2-binding periplasmic protein LuxP precursor [KO:K10910]
VIBNI_B1295  luxQ; Autoinducer 2 sensor kinase/phosphatase luxQ [KO:K10909] [EC:2.7.13.3 3.1.3.-]
VIBNI_B1205  cqsS; CAI-1 autoinducer sensor kinase/phosphatase cqsS [KO:K10916] [EC:2.7.13.3 3.1.3.-]
VIBNI_A0915  luxU; Phosphorelay protein luxU [KO:K10911]
VIBNI_A0914  luxO; Luminescence regulatory protein luxO [KO:K10912]
VIBNI_BmiscRNA_4  Qrr [KO:K15851]
VIBNI_BmiscRNA_5  Qrr [KO:K15851]
VIBNI_BmiscRNA_2  Qrr [KO:K15851]
VIBNI_BmiscRNA_3  Qrr [KO:K15851]
VIBNI_A0184  luxR; HTH-type transcriptional regulator luxR [KO:K10913]
VIBNI_A2438  putative TRAP-type C4-dicarboxylate transport system, periplasmic component [KO:K11688]
VIBNI_A2437  putative TRAP-type C4-dicarboxylate transport system, small permease component [KO:K11689]
VIBNI_A2436  putative TRAP-type C4-dicarboxylate transport system, large permease component DctM [KO:K11690]
VIBNI_A1931  putative TRAP-type C4-dicarboxylate transport system, large permease component DctM [KO:K11690]
VIBNI_B1851  putative TRAP-type C4-dicarboxylate transport system, large permease component [KO:K11690]
VIBNI_A0952  putative TWO COMPONENT HISTIDINE KINASE [KO:K14986] [EC:2.7.13.3]
VIBNI_A0953  fixJ; Transcriptional regulatory protein fixJ [KO:K14987]
VIBNI_A0719  flrA; Sigma 54 transcriptional activator [KO:K10941]
VIBNI_A0720  fleS; Sensor protein FleS [KO:K10942] [EC:2.7.13.3]
VIBNI_A0721  fleR; Transcriptional activator FleR [KO:K10943]
VIBNI_A2452  putative TWO-COMPONENT SENSOR PROTEIN HISTIDINE PROTEIN KINASE [KO:K19691] [EC:2.7.13.3]
VIBNI_A3206  crp; Catabolite gene activator [KO:K10914]
VIBNI_A0048  glsA; Thermolabile glutaminase [KO:K01425] [EC:3.5.1.2]
VIBNI_A0209  petA; Ubiquinol-cytochrome c reductase iron-sulfur subunit [KO:K00411] [EC:7.1.1.8]
VIBNI_A0210  petB; Cytochrome b [KO:K00412]
VIBNI_A0211  putative Cytochrome c1 [KO:K00413]
VIBNI_A1018  putative Cytochrome c [KO:K08738]
VIBNI_A1746  ctaD; Cytochrome c oxidase subunit 1 [KO:K00404] [EC:7.1.1.9]
VIBNI_A1745  ccoO; Cytochrome c oxidase monoheme subunit [KO:K00405]
VIBNI_A1744  ccoQ; Cytochrome c oxidase, subunit CcoQ [KO:K00407]
VIBNI_A1743  ccoP; Cytochrome c oxidase diheme subunit [KO:K00406]
VIBNI_A2264  cydA; Cytochrome d ubiquinol oxidase subunit 1 [KO:K00425] [EC:7.1.1.7]
VIBNI_B0921  cydA; Cytochrome d ubiquinol oxidase subunit 1 [KO:K00425] [EC:7.1.1.7]
VIBNI_A2263  cydB; Cytochrome d ubiquinol oxidase subunit 2 [KO:K00426] [EC:7.1.1.7]
VIBNI_B0922  cydB; Cytochrome d ubiquinol oxidase subunit 2 [KO:K00426] [EC:7.1.1.7]
VIBNI_A0196  tolC; Outer membrane protein tolC [KO:K12340]
VIBNI_A0873  conserved hypothetical protein [KO:K19615]
VIBNI_A3676  putative Periplasmic protein involved in polysaccharide export [KO:K01991]
VIBNI_A2374  Putative low molecular weight protein-tyrosine-phosphatase [KO:K25307] [EC:3.1.3.48]
VIBNI_A3884  putative RNA polymerase sigma factor [KO:K23514]
VIBNI_A3883  putative Fe2+-dicitrate sensor, membrane component FecR [KO:K07165]
VIBNI_A1485  putative Signal transduction histidine kinase SypF [KO:K20974] [EC:2.7.13.3]
VIBNI_A1749  putative TWO-COMPONENT SENSOR PROTEIN HISTIDINE PROTEIN KINASE (DHKK, DHKJ) [KO:K20974] [EC:2.7.13.3]
VIBNI_A1982  putative TWO-COMPONENT SENSOR PROTEIN HISTIDINE PROTEIN KINASE (DHKK, DHKJ) [KO:K20974] [EC:2.7.13.3]
VIBNI_A2231  putative Signal transduction histidine kinase fused with Methyl-accepting/Phosphatase (HAMP) domain [KO:K20974] [EC:2.7.13.3]
VIBNI_A1325  putative SENSOR HISTIDINE KINASE [KO:K20975] [EC:2.7.13.3]
VIBNI_B0018  putative Serine phosphatase RsbU, regulator of sigma subunit fused with Signal receiver domain [KO:K20977]
VIBNI_B0017  putative Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [KO:K20978]
VIBNI_A2646  putative Negative regulator of flagellin synthesis FlgM (anti-sigma28 factor) [KO:K02398]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00034  Manganese
C00036  Oxaloacetate
C00038  Zinc cation
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00070  Copper
C00088  Nitrite
C00092  D-Glucose 6-phosphate
C00122  Fumarate
C00149  (S)-Malate
C00158  Citrate
C00164  Acetoacetate
C00237  CO
C00238  Potassium cation
C00244  Nitrate
C00282  Hydrogen
C00291  Nickel
C00305  Magnesium cation
C00399  Ubiquinone
C00533  Nitric oxide
C00547  L-Noradrenaline
C00697  Nitrogen
C00788  L-Adrenaline
C00828  Menaquinone
C01019  L-Fucose
C01104  Trimethylamine N-oxide
C01667  Bacitracin
C02084  Tetrathionate
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05818  2-Demethylmenaquinone
C06230  Fe-enterobactin
C06689  Vancomycin
C06696  Lead
C11612  Polymyxin B
C11842  N-(3-(S)-Hydroxybutyryl)homoserine lactone
C11849  3-Hydroxy-palmitic acid methyl ester
C12008  Ramoplanin A2
C13768  Colistin sulfate
C14819  Fe3+
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C16665  12-Methyltetradecanoic acid
C18206  cis-11-Methyl-2-dodecenoic acid
C21220  AIP-1
C21221  CSP
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21245  AgrD1 peptide
D07746  Colistin (INN)
D08401  Polymyxin B (INN)
Reference
PMID:15522865
  Authors
Yamamoto K, Hirao K, Oshima T, Aiba H, Utsumi R, Ishihama A.
  Title
Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli.
  Journal
J Biol Chem 280:1448-56 (2005)
DOI:10.1074/jbc.M410104200
Reference
PMID:16030210
  Authors
Abdel-Fattah WR, Chen Y, Eldakak A, Hulett FM.
  Title
Bacillus subtilis phosphorylated PhoP: direct activation of the E(sigma)A- and repression of the E(sigma)E-responsive phoB-PS+V promoters during pho response.
  Journal
J Bacteriol 187:5166-78 (2005)
DOI:10.1128/JB.187.15.5166-5178.2005
Reference
PMID:15813739
  Authors
Navarre WW, Halsey TA, Walthers D, Frye J, McClelland M, Potter JL, Kenney LJ, Gunn JS, Fang FC, Libby SJ.
  Title
Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ.
  Journal
Mol Microbiol 56:492-508 (2005)
DOI:10.1111/j.1365-2958.2005.04553.x
Reference
PMID:11973328
  Authors
Cai SJ, Inouye M.
  Title
EnvZ-OmpR interaction and osmoregulation in Escherichia coli.
  Journal
J Biol Chem 277:24155-61 (2002)
DOI:10.1074/jbc.M110715200
Reference
PMID:16077119
  Authors
Batchelor E, Walthers D, Kenney LJ, Goulian M.
  Title
The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC.
  Journal
J Bacteriol 187:5723-31 (2005)
DOI:10.1128/JB.187.16.5723-5731.2005
Reference
PMID:12107133
  Authors
Nagakubo S, Nishino K, Hirata T, Yamaguchi A.
  Title
The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC.
  Journal
J Bacteriol 184:4161-7 (2002)
DOI:10.1128/JB.184.15.4161-4167.2002
Reference
PMID:15322361
  Authors
Hagiwara D, Yamashino T, Mizuno T.
  Title
A Genome-wide view of the Escherichia coli BasS-BasR two-component system implicated in iron-responses.
  Journal
Biosci Biotechnol Biochem 68:1758-67 (2004)
DOI:10.1271/bbb.68.1758
Reference
PMID:11004187
  Authors
Munson GP, Lam DL, Outten FW, O'Halloran TV.
  Title
Identification of a copper-responsive two-component system on the chromosome of Escherichia coli K-12.
  Journal
J Bacteriol 182:5864-71 (2000)
DOI:10.1128/JB.182.20.5864-5871.2000
Reference
PMID:11929534
  Authors
Sperandio V, Torres AG, Kaper JB.
  Title
Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli.
  Journal
Mol Microbiol 43:809-21 (2002)
DOI:10.1046/j.1365-2958.2002.02803.x
Reference
PMID:14604015
  Authors
Epstein W.
  Title
The roles and regulation of potassium in bacteria.
  Journal
Prog Nucleic Acid Res Mol Biol 75:293-320 (2003)
DOI:10.1016/S0079-6603(03)75008-9
Reference
PMID:10648521
  Authors
Ansaldi M, Simon G, Lepelletier M, Mejean V.
  Title
The TorR high-affinity binding site plays a key role in both torR autoregulation and torCAD operon expression in Escherichia coli.
  Journal
J Bacteriol 182:961-6 (2000)
DOI:10.1128/JB.182.4.961-966.2000
Reference
PMID:15326287
  Authors
Malpica R, Franco B, Rodriguez C, Kwon O, Georgellis D.
  Title
Identification of a quinone-sensitive redox switch in the ArcB sensor kinase.
  Journal
Proc Natl Acad Sci U S A 101:13318-23 (2004)
DOI:10.1073/pnas.0403064101
Reference
PMID:2666399
  Authors
Widenhorn KA, Somers JM, Kay WW.
  Title
Genetic regulation of the tricarboxylate transport operon (tctI) of Salmonella typhimurium.
  Journal
J Bacteriol 171:4436-41 (1989)
DOI:10.1128/JB.171.8.4436-4441.1989
Reference
PMID:11555295
  Authors
Hyyrylainen HL, Bolhuis A, Darmon E, Muukkonen L, Koski P, Vitikainen M, Sarvas M, Pragai Z, Bron S, van Dijl JM, Kontinen VP.
  Title
A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress.
  Journal
Mol Microbiol 41:1159-72 (2001)
DOI:10.1046/j.1365-2958.2001.02576.x
Reference
PMID:10972837
  Authors
Zhang X, Hulett FM.
  Title
ResD signal transduction regulator of aerobic respiration in Bacillus subtilis: ctaA promoter regulation.
  Journal
Mol Microbiol 37:1208-19 (2000)
DOI:10.1046/j.1365-2958.2000.02076.x
Reference
PMID:15937169
  Authors
Senadheera MD, Guggenheim B, Spatafora GA, Huang YC, Choi J, Hung DC, Treglown JS, Goodman SD, Ellen RP, Cvitkovitch DG.
  Title
A VicRK signal transduction system in Streptococcus mutans affects gtfBCD, gbpB, and ftf expression, biofilm formation, and genetic competence development.
  Journal
J Bacteriol 187:4064-76 (2005)
DOI:10.1128/JB.187.12.4064-4076.2005
Reference
PMID:15601704
  Authors
He H, Zahrt TC.
  Title
Identification and characterization of a regulatory sequence recognized by Mycobacterium tuberculosis persistence regulator MprA.
  Journal
J Bacteriol 187:202-12 (2005)
DOI:10.1128/JB.187.1.202-212.2005
Reference
PMID:17448786
  Authors
Hutchings MI
  Title
Unusual two-component signal transduction pathways in the actinobacteria.
  Journal
Adv Appl Microbiol 61:1-26 (2007)
DOI:10.1016/S0065-2164(06)61001-0
Reference
PMID:19308662
  Authors
Kramer R
  Title
Osmosensing and osmosignaling in Corynebacterium glutamicum.
  Journal
Amino Acids 37:487-97 (2009)
DOI:10.1007/s00726-009-0271-6
Reference
PMID:7751278
  Authors
Eraso JM, Kaplan S.
  Title
Oxygen-insensitive synthesis of the photosynthetic membranes of Rhodobacter sphaeroides: a mutant histidine kinase.
  Journal
J Bacteriol 177:2695-706 (1995)
DOI:10.1128/JB.177.10.2695-2706.1995
Reference
PMID:10089160
  Authors
Haydel SE, Dunlap NE, Benjamin WH Jr.
  Title
In vitro evidence of two-component system phosphorylation between the Mycobacterium tuberculosis TrcR/TrcS proteins.
  Journal
Microb Pathog 26:195-206 (1999)
DOI:10.1006/mpat.1998.0265
Reference
PMID:11673427
  Authors
Quisel JD, Burkholder WF, Grossman AD.
  Title
In vivo effects of sporulation kinases on mutant Spo0A proteins in Bacillus subtilis.
  Journal
J Bacteriol 183:6573-8 (2001)
DOI:10.1128/JB.183.22.6573-6578.2001
Reference
PMID:11889485
  Authors
Kaspar S, Bott M.
  Title
The sensor kinase CitA (DpiB) of Escherichia coli functions as a high-affinity citrate receptor.
  Journal
Arch Microbiol 177:313-21 (2002)
DOI:10.1007/s00203-001-0393-z
Reference
PMID:12167640
  Authors
Janausch IG, Garcia-Moreno I, Unden G.
  Title
Function of DcuS from Escherichia coli as a fumarate-stimulated histidine protein kinase in vitro.
  Journal
J Biol Chem 277:39809-14 (2002)
DOI:10.1074/jbc.M204482200
Reference
PMID:8550490
  Authors
Brunskill EW, Bayles KW.
  Title
Identification and molecular characterization of a putative regulatory locus that affects autolysis in Staphylococcus aureus.
  Journal
J Bacteriol 178:611-8 (1996)
DOI:10.1128/JB.178.3.611-618.1996
Reference
PMID:10940023
  Authors
Fujimoto DF, Brunskill EW, Bayles KW.
  Title
Analysis of genetic elements controlling Staphylococcus aureus lrgAB expression: potential role of DNA topology in SarA regulation.
  Journal
J Bacteriol 182:4822-8 (2000)
DOI:10.1128/JB.182.17.4822-4828.2000
Reference
PMID:11807079
  Authors
Dufour P, Jarraud S, Vandenesch F, Greenland T, Novick RP, Bes M, Etienne J, Lina G.
  Title
High genetic variability of the agr locus in Staphylococcus species.
  Journal
J Bacteriol 184:1180-6 (2002)
DOI:10.1128/JB.184.4.1180-1186.2002
Reference
PMID:8501030
  Authors
Rabin RS, Stewart V.
  Title
Dual response regulators (NarL and NarP) interact with dual sensors (NarX and NarQ) to control nitrate- and nitrite-regulated gene expression in Escherichia coli K-12.
  Journal
J Bacteriol 175:3259-68 (1993)
DOI:10.1128/JB.175.11.3259-3268.1993
Reference
PMID:9220011
  Authors
Chiang RC, Cavicchioli R, Gunsalus RP.
  Title
'Locked-on' and 'locked-off' signal transduction mutations in the periplasmic domain of the Escherichia coli NarQ and NarX sensors affect nitrate- and nitrite-dependent regulation by NarL and NarP.
  Journal
Mol Microbiol 24:1049-60 (1997)
DOI:10.1046/j.1365-2958.1997.4131779.x
Reference
PMID:12107138
  Authors
Verhamme DT, Postma PW, Crielaard W, Hellingwerf KJ.
  Title
Cooperativity in signal transfer through the Uhp system of Escherichia coli.
  Journal
J Bacteriol 184:4205-10 (2002)
DOI:10.1128/JB.184.15.4205-4210.2002
Reference
PMID:13129944
  Authors
Hagiwara D, Sugiura M, Oshima T, Mori H, Aiba H, Yamashino T, Mizuno T.
  Title
Genome-wide analyses revealing a signaling network of the RcsC-YojN-RcsB phosphorelay system in Escherichia coli.
  Journal
J Bacteriol 185:5735-46 (2003)
DOI:10.1128/JB.185.19.5735-5746.2003
Reference
PMID:12951338
  Authors
Hirakawa H, Nishino K, Yamada J, Hirata T, Yamaguchi A.
  Title
Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli.
  Journal
J Antimicrob Chemother 52:576-82 (2003)
DOI:10.1093/jac/dkg406
Reference
PMID:12193630
  Authors
Suzuki K, Wang X, Weilbacher T, Pernestig AK, Melefors O, Georgellis D, Babitzke P, Romeo T.
  Title
Regulatory circuitry of the CsrA/CsrB and BarA/UvrY systems of Escherichia coli.
  Journal
J Bacteriol 184:5130-40 (2002)
DOI:10.1128/JB.184.18.5130-5140.2002
Reference
PMID:10923791
  Authors
Kato A, Ohnishi H, Yamamoto K, Furuta E, Tanabe H, Utsumi R.
  Title
Transcription of emrKY is regulated by the EvgA-EvgS two-component system in Escherichia coli K-12.
  Journal
Biosci Biotechnol Biochem 64:1203-9 (2000)
DOI:10.1271/bbb.64.1203
Reference
PMID:14679219
  Authors
Ansaldi M, Dubnau D.
  Title
Diversifying selection at the Bacillus quorum-sensing locus and determinants of modification specificity during synthesis of the ComX pheromone.
  Journal
J Bacteriol 186:15-21 (2004)
DOI:10.1128/JB.186.1.15-21.2004
Reference
PMID:16035234
  Authors
Gabdrakhmanova L, Vishniakov I, Sharipova M, Balaban N, Kostrov S, Leshchinskaya I.
  Title
Salt stress induction of glutamyl endopeptidase biosynthesis in Bacillus intermedius.
  Journal
Microbiol Res 160:233-42 (2005)
DOI:10.1016/j.micres.2004.05.005
Reference
PMID:11285232
  Authors
Aguilar PS, Hernandez-Arriaga AM, Cybulski LE, Erazo AC, de Mendoza D.
  Title
Molecular basis of thermosensing: a two-component signal transduction thermometer in Bacillus subtilis.
  Journal
EMBO J 20:1681-91 (2001)
DOI:10.1093/emboj/20.7.1681
Reference
PMID:12864861
  Authors
Kuroda M, Kuroda H, Oshima T, Takeuchi F, Mori H, Hiramatsu K.
  Title
Two-component system VraSR positively modulates the regulation of cell-wall biosynthesis pathway in Staphylococcus aureus.
  Journal
Mol Microbiol 49:807-21 (2003)
DOI:10.1046/j.1365-2958.2003.03599.x
Reference
PMID:15073296
  Authors
Saini DK, Malhotra V, Dey D, Pant N, Das TK, Tyagi JS.
  Title
DevR-DevS is a bona fide two-component system of Mycobacterium tuberculosis that is hypoxia-responsive in the absence of the DNA-binding domain of DevR.
  Journal
Microbiology 150:865-75 (2004)
DOI:10.1099/mic.0.26218-0
Reference
PMID:12426351
  Authors
Fedtke I, Kamps A, Krismer B, Gotz F.
  Title
The nitrate reductase and nitrite reductase operons and the narT gene of Staphylococcus carnosus are positively controlled by the novel two-component system NreBC.
  Journal
J Bacteriol 184:6624-34 (2002)
DOI:10.1128/JB.184.23.6624-6634.2002
Reference
PMID:8416895
  Authors
Shiau SP, Chen P, Reitzer LJ.
  Title
Effects of insertions and deletions in glnG (ntrC) of Escherichia coli on nitrogen regulator I-dependent DNA binding and transcriptional activation.
  Journal
J Bacteriol 175:190-9 (1993)
DOI:10.1128/JB.175.1.190-199.1993
Reference
PMID:11243806
  Authors
Leonhartsberger S, Huber A, Lottspeich F, Bock A.
  Title
The hydH/G Genes from Escherichia coli code for a zinc and lead responsive two-component regulatory system.
  Journal
J Mol Biol 307:93-105 (2001)
DOI:10.1006/jmbi.2000.4451
Reference
PMID:15200682
  Authors
Lioliou EE, Kyriakidis DA.
  Title
The role of bacterial antizyme: From an inhibitory protein to AtoC transcriptional regulator.
  Journal
Microb Cell Fact 3:8 (2004)
DOI:10.1186/1475-2859-3-8
Reference
PMID:15773991
  Authors
Yamamoto K, Ishihama A
  Title
Transcriptional response of Escherichia coli to external copper.
  Journal
Mol Microbiol 56:215-27 (2005)
DOI:10.1111/j.1365-2958.2005.04532.x
Reference
PMID:10585546
  Authors
Ashby MK, Mullineaux CW
  Title
Cyanobacterial ycf27 gene products regulate energy transfer from phycobilisomes to photosystems I and II.
  Journal
FEMS Microbiol Lett 181:253-60 (1999)
DOI:10.1111/j.1574-6968.1999.tb08852.x
Reference
PMID:11849552
  Authors
Lopez-Maury L, Garcia-Dominguez M, Florencio FJ, Reyes JC
  Title
A two-component signal transduction system involved in nickel sensing in the cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Mol Microbiol 43:247-56 (2002)
DOI:10.1046/j.1365-2958.2002.02741.x
Reference
PMID:17526710
  Authors
Glover RT, Kriakov J, Garforth SJ, Baughn AD, Jacobs WR Jr
  Title
The two-component regulatory system senX3-regX3 regulates phosphate-dependent gene expression in Mycobacterium smegmatis.
  Journal
J Bacteriol 189:5495-503 (2007)
DOI:10.1128/JB.00190-07
Reference
PMID:15175302
  Authors
Hsiao HY, He Q, Van Waasbergen LG, Grossman AR
  Title
Control of photosynthetic and high-light-responsive genes by the histidine kinase DspA: negative and positive regulation and interactions between signal transduction pathways.
  Journal
J Bacteriol 186:3882-8 (2004)
DOI:10.1128/JB.186.12.3882-3888.2004
Reference
PMID:12626498
  Authors
Mutsuda M, Michel KP, Zhang X, Montgomery BL, Golden SS
  Title
Biochemical properties of CikA, an unusual phytochrome-like histidine protein kinase that resets the circadian clock in Synechococcus elongatus PCC 7942.
  Journal
J Biol Chem 278:19102-10 (2003)
DOI:10.1074/jbc.M213255200
Reference
PMID:9278513
  Authors
Yeh KC, Wu SH, Murphy JT, Lagarias JC
  Title
A cyanobacterial phytochrome two-component light sensory system.
  Journal
Science 277:1505-8 (1997)
DOI:10.1126/science.277.5331.1505
Reference
PMID:7635815
  Authors
Niu S, Jiang SQ, Hong J
  Title
Salmonella typhimurium pgtB mutants conferring constitutive expression of phosphoglycerate transporter pgtP independent of pgtC.
  Journal
J Bacteriol 177:4297-302 (1995)
DOI:10.1128/JB.177.15.4297-4302.1995
Reference
PMID:16882723
  Authors
Takai N, Nakajima M, Oyama T, Kito R, Sugita C, Sugita M, Kondo T, Iwasaki H
  Title
A KaiC-associating SasA-RpaA two-component regulatory system as a major circadian timing mediator in cyanobacteria.
  Journal
Proc Natl Acad Sci U S A 103:12109-14 (2006)
DOI:10.1073/pnas.0602955103
Reference
PMID:11803016
  Authors
Janausch IG, Zientz E, Tran QH, Kroger A, Unden G
  Title
C4-dicarboxylate carriers and sensors in bacteria.
  Journal
Biochim Biophys Acta 1553:39-56 (2002)
DOI:10.1016/S0005-2728(01)00233-X
Reference
PMID:18725229
  Authors
Zhou YF, Nan B, Nan J, Ma Q, Panjikar S, Liang YH, Wang Y, Su XD
  Title
C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain.
  Journal
J Mol Biol 383:49-61 (2008)
DOI:10.1016/j.jmb.2008.08.010
Reference
PMID:14523104
  Authors
Novick RP, Jiang D
  Title
The staphylococcal saeRS system coordinates environmental signals with agr quorum sensing.
  Journal
Microbiology 149:2709-17 (2003)
DOI:10.1099/mic.0.26575-0
Reference
PMID:17981963
  Authors
Leech AJ, Sprinkle A, Wood L, Wozniak DJ, Ohman DE
  Title
The NtrC family regulator AlgB, which controls alginate biosynthesis in mucoid Pseudomonas aeruginosa, binds directly to the algD promoter.
  Journal
J Bacteriol 190:581-9 (2008)
DOI:10.1128/JB.01307-07
Reference
PMID:18455986
  Authors
Paul R, Jaeger T, Abel S, Wiederkehr I, Folcher M, Biondi EG, Laub MT, Jenal U
  Title
Allosteric regulation of histidine kinases by their cognate response regulator determines cell fate.
  Journal
Cell 133:452-61 (2008)
DOI:10.1016/j.cell.2008.02.045
Reference
PMID:15101991
  Authors
Whitchurch CB, Leech AJ, Young MD, Kennedy D, Sargent JL, Bertrand JJ, Semmler AB, Mellick AS, Martin PR, Alm RA, Hobbs M, Beatson SA, Huang B, Nguyen L, Commolli JC, Engel JN, Darzins A, Mattick JS.
  Title
Characterization of a complex chemosensory signal transduction system which controls twitching motility in Pseudomonas aeruginosa.
  Journal
Mol Microbiol 52:873-93 (2004)
DOI:10.1111/j.1365-2958.2004.04026.x
Reference
PMID:15170479
  Authors
Yoshihara S, Ikeuchi M.
  Title
Phototactic motility in the unicellular cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Photochem Photobiol Sci 3:512-8 (2004)
DOI:10.1039/b402320j
Reference
PMID:12039966
  Authors
Ogawa T, Bao DH, Katoh H, Shibata M, Pakrasi HB, Bhattacharyya-Pakrasi M
  Title
A two-component signal transduction pathway regulates manganese homeostasis in Synechocystis 6803, a photosynthetic organism.
  Journal
J Biol Chem 277:28981-6 (2002)
DOI:10.1074/jbc.M204175200
Reference
PMID:12417709
  Authors
Yamaguchi K, Suzuki I, Yamamoto H, Lyukevich A, Bodrova I, Los DA, Piven I, Zinchenko V, Kanehisa M, Murata N
  Title
A two-component Mn2+-sensing system negatively regulates expression of the mntCAB operon in Synechocystis.
  Journal
Plant Cell 14:2901-13 (2002)
DOI:10.1105/tpc.006262
Reference
PMID:15273097
  Authors
Mascher T, Zimmer SL, Smith TA, Helmann JD
  Title
Antibiotic-inducible promoter regulated by the cell envelope stress-sensing two-component system LiaRS of Bacillus subtilis.
  Journal
Antimicrob Agents Chemother 48:2888-96 (2004)
DOI:10.1128/AAC.48.8.2888-2896.2004
Reference
PMID:15856219
  Authors
Hyyrylainen HL, Sarvas M, Kontinen VP
  Title
Transcriptome analysis of the secretion stress response of Bacillus subtilis.
  Journal
Appl Microbiol Biotechnol 67:389-96 (2005)
DOI:10.1007/s00253-005-1898-1
Reference
PMID:15941986
  Authors
Serizawa M, Sekiguchi J
  Title
The Bacillus subtilis YdfHI two-component system regulates the transcription of ydfJ, a member of the RND superfamily.
  Journal
Microbiology 151:1769-78 (2005)
DOI:10.1099/mic.0.27619-0
Reference
PMID:12890034
  Authors
Ohki R, Giyanto, Tateno K, Masuyama W, Moriya S, Kobayashi K, Ogasawara N
  Title
The BceRS two-component regulatory system induces expression of the bacitracin transporter, BceAB, in Bacillus subtilis.
  Journal
Mol Microbiol 49:1135-44 (2003)
DOI:10.1046/j.1365-2958.2003.03653.x
Reference
PMID:17322186
  Authors
Ogura M, Tsukahara K, Hayashi K, Tanaka T
  Title
The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion.
  Journal
Microbiology 153:667-75 (2007)
DOI:10.1099/mic.0.2006/003673-0
Reference
PMID:10972810
  Authors
Yamamoto H, Murata M, Sekiguchi J
  Title
The CitST two-component system regulates the expression of the Mg-citrate transporter in Bacillus subtilis.
  Journal
Mol Microbiol 37:898-912 (2000)
DOI:10.1046/j.1365-2958.2000.02055.x
Reference
PMID:15995196
  Authors
Satomura T, Shimura D, Asai K, Sadaie Y, Hirooka K, Fujita Y
  Title
Enhancement of glutamine utilization in Bacillus subtilis through the GlnK-GlnL two-component regulatory system.
  Journal
J Bacteriol 187:4813-21 (2005)
DOI:10.1128/JB.187.14.4813-4821.2005
Reference
PMID:12949160
  Authors
Doan T, Servant P, Tojo S, Yamaguchi H, Lerondel G, Yoshida K, Fujita Y, Aymerich S
  Title
The Bacillus subtilis ywkA gene encodes a malic enzyme and its transcription is activated by the YufL/YufM two-component system in response to malate.
  Journal
Microbiology 149:2331-43 (2003)
DOI:10.1099/mic.0.26256-0
Reference
PMID:12949159
  Authors
Tanaka K, Kobayashi K, Ogasawara N
  Title
The Bacillus subtilis YufLM two-component system regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium.
  Journal
Microbiology 149:2317-29 (2003)
DOI:10.1099/mic.0.26257-0
Reference
PMID:10708364
  Authors
Asai K, Baik SH, Kasahara Y, Moriya S, Ogasawara N
  Title
Regulation of the transport system for C4-dicarboxylic acids in Bacillus subtilis.
  Journal
Microbiology 146 ( Pt 2):263-71 (2000)
DOI:10.1099/00221287-146-2-263
Reference
PMID:8455557
  Authors
Hamblin MJ, Shaw JG, Kelly DJ
  Title
Sequence analysis and interposon mutagenesis of a sensor-kinase (DctS) and response-regulator (DctR) controlling synthesis of the high-affinity C4-dicarboxylate transport system in Rhodobacter capsulatus.
  Journal
Mol Gen Genet 237:215-24 (1993)
DOI:10.1007/BF00282803
Reference
PMID:9287004
  Authors
Forward JA, Behrendt MC, Wyborn NR, Cross R, Kelly DJ
  Title
TRAP transporters: a new family of periplasmic solute transport systems encoded by the dctPQM genes of Rhodobacter capsulatus and by homologs in diverse gram-negative bacteria.
  Journal
J Bacteriol 179:5482-93 (1997)
DOI:10.1128/JB.179.17.5482-5493.1997
Reference
PMID:16820295
  Authors
Martin B, Quentin Y, Fichant G, Claverys JP
  Title
Independent evolution of competence regulatory cascades in streptococci?
  Journal
Trends Microbiol 14:339-45 (2006)
DOI:10.1016/j.tim.2006.06.007
Reference
PMID:10231485
  Authors
Hensel M, Hinsley AP, Nikolaus T, Sawers G, Berks BC
  Title
The genetic basis of tetrathionate respiration in Salmonella typhimurium.
  Journal
Mol Microbiol 32:275-87 (1999)
DOI:10.1046/j.1365-2958.1999.01345.x
Reference
PMID:18028314
  Authors
Guvener ZT, Harwood CS
  Title
Subcellular location characteristics of the Pseudomonas aeruginosa GGDEF protein, WspR, indicate that it produces cyclic-di-GMP in response to growth on surfaces.
  Journal
Mol Microbiol 66:1459-73 (2007)
DOI:10.1111/j.1365-2958.2007.06008.x
Reference
PMID:17339222
  Authors
Bantinaki E, Kassen R, Knight CG, Robinson Z, Spiers AJ, Rainey PB
  Title
Adaptive divergence in experimental populations of Pseudomonas fluorescens. III. Mutational origins of wrinkly spreader diversity.
  Journal
Genetics 176:441-53 (2007)
DOI:10.1534/genetics.106.069906
Reference
PMID:11069677
  Authors
Jiang M, Shao W, Perego M, Hoch JA
  Title
Multiple histidine kinases regulate entry into stationary phase and sporulation in Bacillus subtilis.
  Journal
Mol Microbiol 38:535-42 (2000)
DOI:10.1046/j.1365-2958.2000.02148.x
Reference
PMID:19781638
  Authors
Jenal U
  Title
The role of proteolysis in the Caulobacter crescentus cell cycle and development.
  Journal
Res Microbiol 160:687-95 (2009)
DOI:10.1016/j.resmic.2009.09.006
Reference
PMID:19246239
  Authors
Jenal U, Galperin MY
  Title
Single domain response regulators: molecular switches with emerging roles in cell organization and dynamics.
  Journal
Curr Opin Microbiol 12:152-60 (2009)
DOI:10.1016/j.mib.2009.01.010
Reference
PMID:16640581
  Authors
Drepper T, Wiethaus J, Giaourakis D, Gross S, Schubert B, Vogt M, Wiencek Y, McEwan AG, Masepohl B
  Title
Cross-talk towards the response regulator NtrC controlling nitrogen metabolism in Rhodobacter capsulatus.
  Journal
FEMS Microbiol Lett 258:250-6 (2006)
DOI:10.1111/j.1574-6968.2006.00228.x
Reference
PMID:1661370
  Authors
Pawlowski K, Klosse U, de Bruijn FJ
  Title
Characterization of a novel Azorhizobium caulinodans ORS571 two-component regulatory system, NtrY/NtrX, involved in nitrogen fixation and metabolism.
  Journal
Mol Gen Genet 231:124-38 (1991)
DOI:10.1007/BF00293830
Reference
PMID:18422428
  Authors
Chatterjee S, Almeida RP, Lindow S
  Title
Living in two worlds: the plant and insect lifestyles of Xylella fastidiosa.
  Journal
Annu Rev Phytopathol 46:243-71 (2008)
DOI:10.1146/annurev.phyto.45.062806.094342
Reference
PMID:18506032
  Authors
Dow M
  Title
Diversification of the function of cell-to-cell signaling in regulation of virulence within plant pathogenic xanthomonads.
  Journal
Sci Signal 1:pe23 (2008)
DOI:10.1126/stke.121pe23
Reference
PMID:17902112
  Authors
Colnaghi Simionato AV, da Silva DS, Lambais MR, Carrilho E
  Title
Characterization of a putative Xylella fastidiosa diffusible signal factor by HRGC-EI-MS.
  Journal
J Mass Spectrom 42:1375-81 (2007)
DOI:10.1002/jms.1325
Reference
PMID:19203648
  Authors
Miller LD, Russell MH, Alexandre G
  Title
Diversity in bacterial chemotactic responses and niche adaptation.
  Journal
Adv Appl Microbiol 66:53-75 (2009)
DOI:10.1016/S0065-2164(08)00803-4
Reference
PMID:8760916
  Authors
Eder S, Shi L, Jensen K, Yamane K, Hulett FM
  Title
A Bacillus subtilis secreted phosphodiesterase/alkaline phosphatase is the product of a Pho regulon gene, phoD.
  Journal
Microbiology 142 ( Pt 8):2041-7 (1996)
DOI:10.1099/13500872-142-8-2041
Related
pathway
vni00190  Oxidative phosphorylation
vni00550  Peptidoglycan biosynthesis
vni00910  Nitrogen metabolism
vni02030  Bacterial chemotaxis
vni02040  Flagellar assembly
vni03070  Bacterial secretion system
KO pathway
ko02020   
LinkDB

DBGET integrated database retrieval system