KEGG   PATHWAY: pmy00290Help
Entry
pmy00290                    Pathway                                

Name
Valine, leucine and isoleucine biosynthesis - Pseudomonas mendocina ymp
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
pmy00290  Valine, leucine and isoleucine biosynthesis
pmy00290

Ortholog table
Module
pmy_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:pmy00290]
pmy_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:pmy00290]
pmy_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:pmy00290]
Other DBs
BSID: 50520
GO: 0009097 0009098 0009099
Organism
Pseudomonas mendocina ymp [GN:pmy]
Gene
Pmen_4221  L-threonine ammonia-lyase [KO:K01754] [EC:4.3.1.19]
Pmen_3749  Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [KO:K01754] [EC:4.3.1.19]
Pmen_2723  3-isopropylmalate dehydratase, large subunit [KO:K01703] [EC:4.2.1.35 4.2.1.33]
Pmen_2722  3-isopropylmalate dehydratase, small subunit [KO:K01704] [EC:4.2.1.35 4.2.1.33]
Pmen_2721  3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
Pmen_1006  acetolactate synthase, large subunit [KO:K01652] [EC:2.2.1.6]
Pmen_1795  thiamine pyrophosphate enzyme TPP binding domain protein [KO:K01652] [EC:2.2.1.6]
Pmen_1007  acetolactate synthase, small subunit [KO:K01653] [EC:2.2.1.6]
Pmen_1009  ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
Pmen_4205  dihydroxyacid dehydratase [KO:K01687] [EC:4.2.1.9]
Pmen_0578  branched chain amino acid aminotransferase apoenzyme [KO:K00826] [EC:2.6.1.42]
Pmen_3248  Glu/Leu/Phe/Val dehydrogenase, dimerization region [KO:K00263] [EC:1.4.1.9]
Pmen_2875  Glu/Leu/Phe/Val dehydrogenase, dimerization region [KO:K00263] [EC:1.4.1.9]
Pmen_2522  aminotransferase [KO:K14260] [EC:2.6.1.2 2.6.1.66]
Pmen_3492  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Pmen_0989  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
KO pathway
ko00290   
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