KEGG   PATHWAY: psom00350
Entry
psom00350                   Pathway                                
Name
Tyrosine metabolism - Papaver somniferum (opium poppy)
Class
Metabolism; Amino acid metabolism
Pathway map
psom00350  Tyrosine metabolism
psom00350

Module
psom_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:psom00350]
Other DBs
GO: 0006570
Organism
Papaver somniferum (opium poppy) [GN:psom]
Gene
113303925  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
113338059  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
113348271  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
113349091  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
113302191  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
113297005  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
113282685  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
113355938  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
113331727  bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase-like isoform X1 [KO:K15849] [EC:2.6.1.1 2.6.1.78 2.6.1.79]
113347486  bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase-like isoform X1 [KO:K15849] [EC:2.6.1.1 2.6.1.78 2.6.1.79]
113318550  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113334119  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113335775  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113287557  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113341707  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113335631  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113341807  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113352867  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113353418  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113348796  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113350549  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113308110  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113283205  histidinol-phosphate aminotransferase, chloroplastic-like isoform X1 [KO:K00817] [EC:2.6.1.9]
113296976  histidinol-phosphate aminotransferase 1, chloroplastic-like isoform X1 [KO:K00817] [EC:2.6.1.9]
113312924  4-hydroxyphenylpyruvate dioxygenase-like isoform X1 [KO:K00457] [EC:1.13.11.27]
113323802  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
113335184  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
113352204  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
113349425  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
113349428  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
113359607  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
113287515  homogentisate 1,2-dioxygenase-like isoform X1 [KO:K00451] [EC:1.13.11.5]
113308157  homogentisate 1,2-dioxygenase-like isoform X1 [KO:K00451] [EC:1.13.11.5]
113305355  glutathione S-transferase 2-like [KO:K01800] [EC:5.2.1.2]
113304808  glutathione S-transferase 2-like [KO:K01800] [EC:5.2.1.2]
113284396  glutathione S-transferase zeta class-like [KO:K01800] [EC:5.2.1.2]
113284397  glutathione S-transferase zeta class-like [KO:K01800] [EC:5.2.1.2]
113275147  glutathione S-transferase 2-like [KO:K01800] [EC:5.2.1.2]
113355551  glutathione S-transferase zeta class-like [KO:K01800] [EC:5.2.1.2]
113333674  fumarylacetoacetase-like [KO:K01555] [EC:3.7.1.2]
113348506  fumarylacetoacetase-like [KO:K01555] [EC:3.7.1.2]
113318085  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113318091  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113325989  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113326693  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113310294  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113313874  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113288662  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113330934  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113287664  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113320211  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113284640  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113284645  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113306281  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113339778  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113288165  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113339945  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113276280  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113276320  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113291222  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113335035  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113321283  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113304358  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113317407  aureusidin synthase-like [KO:K00422] [EC:1.10.3.1]
113345373  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113322011  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113291768  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113344239  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113344391  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113276494  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113278524  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113290244  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113349439  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113358933  polyphenol oxidase I, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113353825  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
113300024  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113300033  tyrosine/DOPA decarboxylase 5-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113300401  tyrosine decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113317135  tyrosine decarboxylase 1-like isoform X1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113317142  tyrosine/DOPA decarboxylase 2-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113335689  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113336160  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113336161  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113336168  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113336188  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113336203  tyrosine/DOPA decarboxylase 1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113275368  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113282258  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113315171  tyrosine decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113285898  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113289816  tyrosine/DOPA decarboxylase 5 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113300565  tyrosine/DOPA decarboxylase 2 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113328604  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113328798  tryptophan decarboxylase TDC2-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113342821  tryptophan decarboxylase TDC2-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113286311  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113286782  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113286784  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113286785  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113282799  tyrosine/DOPA decarboxylase 3 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113348283  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113349848  tyrosine decarboxylase 1-like isoform X1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113355837  tyrosine/DOPA decarboxylase 3-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113347922  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113349080  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113349082  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113355340  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
113344052  uncharacterized protein LOC113344052 [KO:K00276] [EC:1.4.3.21]
113347115  primary amine oxidase 1-like [KO:K00276] [EC:1.4.3.21]
113346310  primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
113282356  uncharacterized protein LOC113282356 [KO:K00276] [EC:1.4.3.21]
113296430  primary amine oxidase 1-like [KO:K00276] [EC:1.4.3.21]
113304618  uncharacterized protein LOC113304618 [KO:K00276] [EC:1.4.3.21]
113340990  primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
113275136  uncharacterized protein LOC113275136 [KO:K00276] [EC:1.4.3.21]
113305321  primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
113317514  uncharacterized protein LOC113317514 isoform X1 [KO:K00276] [EC:1.4.3.21]
113335942  uncharacterized protein LOC113335942 [KO:K00276] [EC:1.4.3.21]
113276172  uncharacterized protein LOC113276172 isoform X1 [KO:K00276] [EC:1.4.3.21]
113275220  primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
113275222  primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
113305398  primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
113350725  primary amine oxidase 2-like [KO:K00276] [EC:1.4.3.21]
113290229  alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113285357  alcohol dehydrogenase-like 5 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113311956  alcohol dehydrogenase-like 1 isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113311965  alcohol dehydrogenase-like 1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113318175  alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113278682  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113286745  alcohol dehydrogenase-like 1 isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113286746  alcohol dehydrogenase-like 1 isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113286744  alcohol dehydrogenase-like 1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113349863  alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
113284578  alcohol dehydrogenase 2 [KO:K18857] [EC:1.1.1.1]
113284587  alcohol dehydrogenase 1-like [KO:K18857] [EC:1.1.1.1]
113288398  alcohol dehydrogenase 2-like [KO:K18857] [EC:1.1.1.1]
113288400  alcohol dehydrogenase 1-like [KO:K18857] [EC:1.1.1.1]
113299633  alcohol dehydrogenase-like 6 [KO:K00001] [EC:1.1.1.1]
113303476  alcohol dehydrogenase-like 6 [KO:K00001] [EC:1.1.1.1]
113335157  alcohol dehydrogenase-like 3 [KO:K00001] [EC:1.1.1.1]
113346553  probable acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
113345495  probable acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
113355197  probable acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
113322445  macrophage migration inhibitory factor homolog isoform X1 [KO:K07253] [EC:5.3.2.1]
113329228  macrophage migration inhibitory factor homolog isoform X1 [KO:K07253] [EC:5.3.2.1]
113310569  macrophage migration inhibitory factor homolog isoform X1 [KO:K07253] [EC:5.3.2.1]
113340649  macrophage migration inhibitory factor homolog [KO:K07253] [EC:5.3.2.1]
113298891  macrophage migration inhibitory factor homolog [KO:K07253] [EC:5.3.2.1]
113358665  macrophage migration inhibitory factor homolog [KO:K07253] [EC:5.3.2.1]
113348278  hydroxyphenylpyruvate reductase-like [KO:K18606] [EC:1.1.1.237]
113349087  hydroxyphenylpyruvate reductase-like [KO:K18606] [EC:1.1.1.237]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
psom00020  Citrate cycle (TCA cycle)
psom00360  Phenylalanine metabolism
psom00400  Phenylalanine, tyrosine and tryptophan biosynthesis
psom00620  Pyruvate metabolism
psom00650  Butanoate metabolism
psom00940  Phenylpropanoid biosynthesis
psom00950  Isoquinoline alkaloid biosynthesis
KO pathway
ko00350   
LinkDB

DBGET integrated database retrieval system