PATHWAY: rn00622 Help
Entry Name Xylene degradation
Class Metabolism; Xenobiotics biodegradation and metabolism
Pathway map Module M00537 Xylene degradation, xylene => methylbenzoate [PATH:rn00622 ]
M00539 Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate [PATH:rn00622 ]
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:rn00622 ]
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:rn00622 ]
Other DBs Reaction R00228 acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)
R00750 4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming)
R02601 4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)
R04089 3-methylcatechol:oxygen 2,3-oxidoreductase(decyclizing)
R05138 2-hydroxy-6-oxohepta-2,4-dienoate acetylhydrolase
R05232 p-cumic alcohol:NAD+ oxidoreductase
R05235 p-cumic aldehyde:NAD+ oxidoreductase
R05240 cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase
R05247 4-isopropylbenzoate:oxygen 2,3-oxidoreductase
R05266 p-cymene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating)
R05282 4-methylbenzyl alcohol:NAD+ oxidoreductase
R05288 p-xylene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating)
R05289 p-methylbenzaldehyde:NADP+ oxidoreductase
R05292 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
R05293 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NADP+ oxidoreductase (decarboxylating)
R05295 4-methylcatechol:oxygen 2,3-oxidoreductase(decyclizing)
R05298 4-hydroxy-2-oxohexanoate pyruvate-lyase (propanal-forming)
R05309 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate:NAD+ oxidoreductase (decarboxylating)
R05314 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating)
R05353 2-hydroxy-5-methyl-cis,cis-muconic semialdehyde:NAD+ 6-oxidoreductase
R05364 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate acylhydrolase
R05374 2-oxo-5-methyl-cis-muconate carboxy-lyase
R05377 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate carboxy-lyase
R05389 2-hydroxy-5-methyl-cis,cis-muconate 2-oxo-5-methyl-cis-muconate isomerase
R05442 o-xylene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating)
R05443 m-xylene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating)
R05864 4-hydroxy-2-oxohexanoate hydro-lyase
R05865 2-hydroxy-5-methyl-cis,cis-muconic-semialdehyde formylhydrolase
R09097 propanal:NAD+ oxidoreductase (CoA-propanoylating)
Compound C00596 2-Hydroxy-2,4-pentadienoate
C03589 4-Hydroxy-2-oxopentanoate
C06210 2-Hydroxy-6-keto-2,4-heptadienoate
C06577 4-Isopropylbenzaldehyde
C06579 cis-2,3-Dihydroxy-2,3-dihydro-p-cumate
C06581 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate
C06582 2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate
C06720 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate
C06729 cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
C06731 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate
C06760 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
C06762 4-Hydroxy-2-oxohexanoic acid
C07478 2-Hydroxy-5-methyl-cis,cis-muconate
C07479 2-Oxo-5-methyl-cis-muconate
C11354 2-Hydroxy-cis-hex-2,4-dienoate
Reference Authors Haddad S, Eby DM, Neidle EL.
Title Cloning and expression of the benzoate dioxygenase genes from Rhodococcus sp. strain 19070.
Journal Reference Authors Kim E, Zylstra GJ
Title Molecular and biochemical characterization of two meta-cleavage dioxygenases involved in biphenyl and m-xylene degradation by Beijerinckia sp. strain B1.
Journal Reference Authors Morasch B, Schink B, Tebbe CC, Meckenstock RU
Title Degradation of o-xylene and m-xylene by a novel sulfate-reducer belonging to the genus Desulfotomaculum.
Journal Reference Authors Eaton RW.
Title p-Cymene catabolic pathway in Pseudomonas putida F1: cloning and characterization of DNA encoding conversion of p-cymene to p-cumate.
Journal Reference Authors Eaton RW.
Title p-Cumate catabolic pathway in Pseudomonas putida Fl: cloning and characterization of DNA carrying the cmt operon.
Journal Related rn00010 Glycolysis / Gluconeogenesis
KO pathway
