KEGG   PATHWAY: rn00643
Entry
rn00643                     Pathway                                
Name
Styrene degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
rn00643  Styrene degradation
rn00643

Other DBs
UMBBD: sty acr pao
GO: 0042207
Reaction
R01364  4-fumarylacetoacetate fumarylhydrolase
R02517  3-hydroxyphenylacetate,NADPH:oxygen oxidoreductase (6-hydroxylating)
R02519  homogentisate:oxygen 1,2-oxidoreductase (decyclizing)
R02536  phenylacetaldehyde:NAD+ oxidoreductase
R02540  2-phenylacetamide amidohydrolase
R02963  lactoyl-CoA hydro-lyase
R03181  4-maleylacetoacetate cis-trans-isomerase
R05354  styrene cis-glycol:NAD+ oxidoreductase
R05358  acrylonitrile aminohydrolase
R05362  2-hydroxy-6-oxoocta-2,4,7-trienoate formylhydrolase
R05379  acrylamide hydro-lyase
R05404   
R05417   
R05450   
R05487  phenylacetate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating)
R05488  styrene,FADH2:oxygen oxidoreductase
R05508   
R05509   
R05551   
R07638  (Z)-phenylacetaldehyde-oxime hydro-lyase
R07854  2-phenylacetamide hydro-lyase (nitrile-forming)
R07855  phenylacetonitrile aminohydrolase
R10697  styrene-oxide isomerase (epoxide-cleaving)
Compound
C00122  Fumarate
C00164  Acetoacetate
C00186  (S)-Lactate
C00511  Acrylic acid
C00544  Homogentisate
C00596  2-Hydroxy-2,4-pentadienoate
C00601  Phenylacetaldehyde
C00827  Lactoyl-CoA
C00894  Propenoyl-CoA
C01036  4-Maleylacetoacetate
C01061  4-Fumarylacetoacetate
C01659  Acrylamide
C01998  Acrylonitrile
C02505  2-Phenylacetamide
C05593  3-Hydroxyphenylacetate
C05852  2-Hydroxyphenylacetate
C07083  Styrene
C07084  Styrene-cis-2,3-dihydrodiol
C07085  3-Vinylcatechol
C07086  Phenylacetic acid
C07087  2-Hydroxy-6-oxoocta-2,4,7-trienoate
C16074  Phenylacetonitrile
C16075  (Z)-Phenylacetaldehyde oxime
C20782  (S)-2-Phenyloxirane
Reference
PMID:11544206
  Authors
Rodriguez-Saiz M, Barredo JL, Moreno MA, Fernandez-Canon JM, Penalva MA, Diez B.
  Title
Reduced function of a phenylacetate-oxidizing cytochrome p450 caused strong genetic improvement in early phylogeny of penicillin-producing strains.
  Journal
J Bacteriol 183:5465-71 (2001)
DOI:10.1128/JB.183.19.5465-5471.2001
Reference
PMID:17189487
  Authors
Ferrer-Sevillano F, Fernandez-Canon JM.
  Title
Novel phacB-encoded cytochrome P450 monooxygenase from Aspergillus nidulans with 3-hydroxyphenylacetate 6-hydroxylase and 3,4-dihydroxyphenylacetate 6-hydroxylase activities.
  Journal
Eukaryot Cell 6:514-20 (2007)
DOI:10.1128/EC.00226-06
Related
pathway
rn00020  Citrate cycle (TCA cycle)
rn00360  Phenylalanine metabolism
rn00362  Benzoate degradation
rn00620  Pyruvate metabolism
rn00640  Propanoate metabolism
rn00642  Ethylbenzene degradation
KO pathway
ko00643   
LinkDB

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