KEGG   PATHWAY: ko00643
Entry
ko00643                     Pathway                                
Name
Styrene degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
ko00643  Styrene degradation
ko00643

Other DBs
UMBBD: sty acr pao
GO: 0042207
Orthology
K00146  feaB, tynC; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
K00446  dmpB, xylE; catechol 2,3-dioxygenase [EC:1.13.11.2]
K00451  HGD, hmgA; homogentisate 1,2-dioxygenase [EC:1.13.11.5]
K01026  pct; propionate CoA-transferase [EC:2.8.3.1]
K01039  gctA; glutaconate CoA-transferase, subunit A [EC:2.8.3.12]
K01040  gctB; glutaconate CoA-transferase, subunit B [EC:2.8.3.12]
K01426  E3.5.1.4, amiE; amidase [EC:3.5.1.4]
K01501  E3.5.5.1; nitrilase [EC:3.5.5.1]
K01502  E3.5.5.7; aliphatic nitrilase [EC:3.5.5.7]
K01555  FAH, fahA; fumarylacetoacetase [EC:3.7.1.2]
K01721  nthA; nitrile hydratase subunit alpha [EC:4.2.1.84]
K01800  maiA, GSTZ1; maleylacetoacetate isomerase [EC:5.2.1.2]
K07104  catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
K10216  dmpD, xylF; 2-hydroxymuconate-semialdehyde hydrolase [EC:3.7.1.9]
K10437  PHAA, PHACA, CYP504A1; phenylacetate 2-hydroxylase [EC:1.14.14.54]
K10438  PHACB, CYP504B1; 3-hydroxyphenylacetate 6-hydroxylase [EC:1.14.13.63]
K10566  oxdB; phenylacetaldoxime dehydratase [EC:4.8.1.4]
K14481  styA; styrene monooxygenase [EC:1.14.14.11]
K14482  styB; styrene monooxygenase reductase component [EC:1.5.1.-]
K16171  faaH; fumarylacetoacetate (FAA) hydrolase [EC:3.7.1.2]
K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase [EC:1.3.1.19 1.3.1.119]
K18312  styC; styrene-oxide isomerase [EC:5.3.99.7]
K20626  lcdA; lactoyl-CoA dehydratase subunit alpha [EC:4.2.1.54]
K20627  lcdB; lactoyl-CoA dehydratase subunit beta [EC:4.2.1.54]
K20807  nthB; nitrile hydratase subunit beta [EC:4.2.1.84]
Compound
C00122  Fumarate
C00164  Acetoacetate
C00186  (S)-Lactate
C00511  Acrylic acid
C00544  Homogentisate
C00596  2-Hydroxy-2,4-pentadienoate
C00601  Phenylacetaldehyde
C00827  Lactoyl-CoA
C00894  Propenoyl-CoA
C01036  4-Maleylacetoacetate
C01061  4-Fumarylacetoacetate
C01659  Acrylamide
C01998  Acrylonitrile
C02505  2-Phenylacetamide
C05593  3-Hydroxyphenylacetate
C05852  2-Hydroxyphenylacetate
C07083  Styrene
C07084  Styrene-cis-2,3-dihydrodiol
C07085  3-Vinylcatechol
C07086  Phenylacetic acid
C07087  2-Hydroxy-6-oxoocta-2,4,7-trienoate
C16074  Phenylacetonitrile
C16075  (Z)-Phenylacetaldehyde oxime
C20782  (S)-2-Phenyloxirane
Reference
PMID:11544206
  Authors
Rodriguez-Saiz M, Barredo JL, Moreno MA, Fernandez-Canon JM, Penalva MA, Diez B.
  Title
Reduced function of a phenylacetate-oxidizing cytochrome p450 caused strong genetic improvement in early phylogeny of penicillin-producing strains.
  Journal
J Bacteriol 183:5465-71 (2001)
DOI:10.1128/JB.183.19.5465-5471.2001
Reference
PMID:17189487
  Authors
Ferrer-Sevillano F, Fernandez-Canon JM.
  Title
Novel phacB-encoded cytochrome P450 monooxygenase from Aspergillus nidulans with 3-hydroxyphenylacetate 6-hydroxylase and 3,4-dihydroxyphenylacetate 6-hydroxylase activities.
  Journal
Eukaryot Cell 6:514-20 (2007)
DOI:10.1128/EC.00226-06
Related
pathway
ko00020  Citrate cycle (TCA cycle)
ko00360  Phenylalanine metabolism
ko00362  Benzoate degradation
ko00620  Pyruvate metabolism
ko00640  Propanoate metabolism
ko00642  Ethylbenzene degradation

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