KEGG   PATHWAY: rrt00622
Entry
rrt00622                    Pathway                                
Name
Xylene degradation - Rhodococcus rhodochrous
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
rrt00622  Xylene degradation
rrt00622

Module
rrt_M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:rrt00622]
Other DBs
GO: 0042184
UMBBD: mxy oxy pxy pcy tol
Organism
Rhodococcus rhodochrous [GN:rrt]
Gene
4535765_00187  cmtA1_1; p-cumate dioxygenase large subunit [KO:K10619] [EC:1.14.12.25]
4535765_00188  cmtA2_1; p-cumate dioxygenase small subunit [KO:K16303] [EC:1.14.12.25]
4535765_00324  xylC_1; benzaldehyde dehydrogenase [KO:K00141] [EC:1.2.1.28]
4535765_00363  xylB_1; aryl-alcohol dehydrogenase [KO:K00055] [EC:1.1.1.90]
4535765_00374  cmtA2_2; p-cumate dioxygenase small subunit [KO:K16303] [EC:1.14.12.25]
4535765_00375  cmtA1_2; p-cumate dioxygenase large subunit [KO:K10619] [EC:1.14.12.25]
4535765_00422  xylB_2; zinc binding alcohol dehydrogenase [KO:K00055] [EC:1.1.1.90]
4535765_01218  xylC_2; benzaldehyde dehydrogenase [KO:K00141] [EC:1.2.1.28]
4535765_01257  amnE; 4-oxalocrotonate decarboxylase [KO:K01617] [EC:4.1.1.77]
4535765_01258  amnC_1; 2-aminomuconic semialdehyde dehydrogenase [KO:K10217] [EC:1.2.1.32 1.2.1.85]
4535765_01264  amnC_2; 2-aminomuconic semialdehyde dehydrogenase [KO:K10217] [EC:1.2.1.32 1.2.1.85]
4535765_02887  dmpI; tautomerase [KO:K01821] [EC:5.3.2.6]
4535765_04589  xylF_2; alpha/beta hydrolase [KO:K10216] [EC:3.7.1.9]
4535765_04641  benA; benzoate 1,2-dioxygenase large subunit [KO:K05549] [EC:1.14.12.10 1.14.12.-]
4535765_04642  benB; benzoate 1,2-dioxygenase subunit beta [KO:K05550] [EC:1.14.12.10 1.14.12.-]
4535765_04643  benC; benzoate 1,2-dioxygenase reductase component [KO:K05784] [EC:1.18.1.-]
4535765_04644  benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase [KO:K05783] [EC:1.3.1.25 1.3.1.-]
4535765_04741  mhpE; 4-hydroxy-2-ketovalerate aldolase [KO:K01666] [EC:4.1.3.39]
4535765_04742  dmpF; acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
4535765_04743  cmtF; 2-hydroxypenta-2,4-dienoate hydratase CmtF [KO:K02554] [EC:4.2.1.80]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00084  Acetaldehyde
C00100  Propanoyl-CoA
C00479  Propanal
C00596  2-Hydroxy-2,4-pentadienoate
C01454  Toluate
C02923  2,3-Dihydroxytoluene
C03589  4-Hydroxy-2-oxopentanoate
C06210  2-Hydroxy-6-keto-2,4-heptadienoate
C06575  p-Cymene
C06576  p-Cumic alcohol
C06577  4-Isopropylbenzaldehyde
C06578  p-Cumate
C06579  cis-2,3-Dihydroxy-2,3-dihydro-p-cumate
C06580  2,3-Dihydroxy-p-cumate
C06581  2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate
C06582  2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate
C06720  1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate
C06729  cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
C06730  4-Methylcatechol
C06731  1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate
C06756  p-Xylene
C06757  4-Methylbenzyl alcohol
C06758  p-Tolualdehyde
C06760  2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
C06762  4-Hydroxy-2-oxohexanoic acid
C07208  m-Xylene
C07209  3-Methylbenzaldehyde
C07211  m-Methylbenzoate
C07212  o-Xylene
C07213  2-Methylbenzyl alcohol
C07214  2-Methylbenzaldehyde
C07215  o-Toluate
C07216  3-Methylbenzyl alcohol
C07478  2-Hydroxy-5-methyl-cis,cis-muconate
C07479  2-Oxo-5-methyl-cis-muconate
C11354  2-Hydroxy-cis-hex-2,4-dienoate
Reference
PMID:11375157
  Authors
Haddad S, Eby DM, Neidle EL.
  Title
Cloning and expression of the benzoate dioxygenase genes from Rhodococcus sp. strain 19070.
  Journal
Appl Environ Microbiol 67:2507-14 (2001)
DOI:10.1128/AEM.67.6.2507-2514.2001
Reference
PMID:7768806
  Authors
Kim E, Zylstra GJ
  Title
Molecular and biochemical characterization of two meta-cleavage dioxygenases involved in biphenyl and m-xylene degradation by Beijerinckia sp. strain B1.
  Journal
J Bacteriol 177:3095-103 (1995)
DOI:10.1128/JB.177.11.3095-3103.1995
Reference
PMID:15127183
  Authors
Morasch B, Schink B, Tebbe CC, Meckenstock RU
  Title
Degradation of o-xylene and m-xylene by a novel sulfate-reducer belonging to the genus Desulfotomaculum.
  Journal
Arch Microbiol 181:407-17 (2004)
DOI:10.1007/s00203-004-0672-6
Reference
PMID:9150211
  Authors
Eaton RW.
  Title
p-Cymene catabolic pathway in Pseudomonas putida F1: cloning and characterization of DNA encoding conversion of p-cymene to p-cumate.
  Journal
J Bacteriol 179:3171-80 (1997)
DOI:10.1128/JB.179.10.3171-3180.1997
Reference
PMID:8631713
  Authors
Eaton RW.
  Title
p-Cumate catabolic pathway in Pseudomonas putida Fl: cloning and characterization of DNA carrying the cmt operon.
  Journal
J Bacteriol 178:1351-62 (1996)
DOI:10.1128/JB.178.5.1351-1362.1996
Related
pathway
rrt00010  Glycolysis / Gluconeogenesis
rrt00020  Citrate cycle (TCA cycle)
rrt00623  Toluene degradation
rrt00640  Propanoate metabolism
KO pathway
ko00622   

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