KEGG   PATHWAY: salp00533
Entry
salp00533                   Pathway                                
Name
Glycosaminoglycan biosynthesis - keratan sulfate - Salvelinus sp. IW2-2015 (Arctic char)
Description
Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, Gal(b1-4)GlcNAc(b1-3), with sulfate esters at C-6 of GlcNAc and Gal residues. There are two types of KS distinguished by the protein linkage: type I for N-linked via the N-glycan core structure and type II for O-linked via the O-glycan core 2 structure.
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
salp00533  Glycosaminoglycan biosynthesis - keratan sulfate
salp00533

Other DBs
GO: 0018146
Organism
Salvelinus sp. IW2-2015 (Arctic char) [GN:salp]
Gene
111950662  [KO:K07969] [EC:2.4.1.90 2.4.1.275 2.4.1.-]
111952695  [KO:K03368] [EC:2.4.3.2 2.4.3.4]
111952822  [KO:K01022] [EC:2.8.2.21]
111952911  [KO:K09671] [EC:2.8.2.-]
111952950  [KO:K01022] [EC:2.8.2.21]
111954040  [KO:K00717] [EC:2.4.1.68]
111955199  [KO:K00780] [EC:2.4.3.2 2.4.3.4]
111956066  [KO:K00780] [EC:2.4.3.2 2.4.3.4]
111956573  [KO:K00781] [EC:2.4.3.6]
111956847  [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
111959039  [KO:K00741] [EC:2.4.1.149]
111959078  [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
111961183  [KO:K01022] [EC:2.8.2.21]
111962752  [KO:K01022] [EC:2.8.2.21]
111964175  [KO:K00741] [EC:2.4.1.149]
111964307  b4galt4; beta-1,4-galactosyltransferase 4 isoform X1 [KO:K07969] [EC:2.4.1.90 2.4.1.275 2.4.1.-]
111965171  [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
111965529  [KO:K00741] [EC:2.4.1.149]
111965773  [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
111966557  [KO:K09664] [EC:2.4.1.-]
111967089  [KO:K00741] [EC:2.4.1.149]
111967527  [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
111971603  [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
111971604  [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
111972384  [KO:K00781] [EC:2.4.3.6]
111972986  [KO:K04745] [EC:2.8.2.-]
111975802  [KO:K00781] [EC:2.4.3.6]
111976535  b4galt3; beta-1,4-galactosyltransferase 3 [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
111977139  [KO:K09664] [EC:2.4.1.-]
111979130  [KO:K00781] [EC:2.4.3.6]
111979246  [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
112068292  [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
112069580  [KO:K04745] [EC:2.8.2.-]
112069687  st3gal2; CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 2 [KO:K03368] [EC:2.4.3.2 2.4.3.4]
112072476  b3gnt7; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [KO:K09664] [EC:2.4.1.-]
112075323  [KO:K00717] [EC:2.4.1.68]
112077816  [KO:K00741] [EC:2.4.1.149]
112080874  [KO:K00741] [EC:2.4.1.149]
Reference
PMID:11030741
  Authors
Funderburgh JL.
  Title
Keratan sulfate: structure, biosynthesis, and function.
  Journal
Glycobiology 10:951-958 (2000)
DOI:10.1093/glycob/10.10.951
Reference
PMID:14706853
  Authors
Seko A, Yamashita K.
  Title
beta1,3-N-Acetylglucosaminyltransferase-7 (beta3Gn-T7) acts efficiently on keratan sulfate-related glycans.
  Journal
FEBS Lett 556:216-20 (2004)
DOI:10.1016/S0014-5793(03)01440-6
Reference
PMID:12511560
  Authors
Seko A, Dohmae N, Takio K, Yamashita K.
  Title
Beta 1,4-galactosyltransferase (beta 4GalT)-IV is specific for GlcNAc 6-O-sulfate. Beta 4GalT-IV acts on keratan sulfate-related glycans and a precursor glycan of 6-sulfosialyl-Lewis X.
  Journal
J Biol Chem 278:9150-8 (2003)
DOI:10.1074/jbc.M211480200
Related
pathway
salp00510  N-Glycan biosynthesis
salp00512  Mucin type O-glycan biosynthesis
KO pathway
ko00533   

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