KEGG   PATHWAY: seno00290
Entry
seno00290                   Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Salmonella enterica subsp. enterica serovar Enteritidis EC20090193
Class
Metabolism; Amino acid metabolism
Pathway map
seno00290  Valine, leucine and isoleucine biosynthesis
seno00290

Module
seno_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:seno00290]
seno_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:seno00290]
seno_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:seno00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Salmonella enterica subsp. enterica serovar Enteritidis EC20090193 [GN:seno]
Gene
AU37_15910  threonine dehydratase [KO:K01754] [EC:4.3.1.19]
AU37_19150  threonine dehydratase [KO:K01754] [EC:4.3.1.19]
AU37_00560  isopropylmalate isomerase [KO:K01703] [EC:4.2.1.33 4.2.1.35]
AU37_01585  isopropylmalate isomerase [KO:K01703] [EC:4.2.1.33 4.2.1.35]
AU37_00555  leuD; isopropylmalate isomerase [KO:K01704] [EC:4.2.1.33 4.2.1.35]
AU37_01590  3-isopropylmalate dehydratase [KO:K01704] [EC:4.2.1.33 4.2.1.35]
AU37_00565  3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
AU37_00580  acetolactate synthase 3 catalytic subunit [KO:K01652] [EC:2.2.1.6]
AU37_19130  acetolactate synthase catalytic subunit [KO:K01652] [EC:2.2.1.6]
AU37_18630  acetolactate synthase catalytic subunit [KO:K01652] [EC:2.2.1.6]
AU37_00585  ilvH; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
AU37_18625  acetolactate synthase isozyme 1 small subunit [KO:K01653] [EC:2.2.1.6]
AU37_19135  ilvM; acetolactate synthase 2 regulatory subunit [KO:K11258] [EC:2.2.1.6]
AU37_19170  ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
AU37_19145  dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
AU37_17310  dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
AU37_19140  branched chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
AU37_18005  avtA; valine--pyruvate aminotransferase [KO:K00835] [EC:2.6.1.66]
AU37_11705  aminotransferase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
AU37_00570  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
seno00260  Glycine, serine and threonine metabolism
seno00280  Valine, leucine and isoleucine degradation
seno00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

DBGET integrated database retrieval system