KEGG   PATHWAY: sly00290
Entry
sly00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Solanum lycopersicum (tomato)
Class
Metabolism; Amino acid metabolism
Pathway map
sly00290  Valine, leucine and isoleucine biosynthesis
sly00290

Module
sly_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sly00290]
sly_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sly00290]
sly_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sly00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Solanum lycopersicum (tomato) [GN:sly]
Gene
543983  TD2; threonine dehydratase 2 biosynthetic, chloroplastic [KO:K01754] [EC:4.3.1.19]
101244823  threonine dehydratase biosynthetic, chloroplastic-like [KO:K01754] [EC:4.3.1.19]
100037737  chloroplast threonine deaminase 1 precursor [KO:K01754] [EC:4.3.1.19]
101266391  3-isopropylmalate dehydratase large subunit, chloroplastic [KO:K01703] [EC:4.2.1.33 4.2.1.35]
101244614  3-isopropylmalate dehydratase large subunit, chloroplastic [KO:K01703] [EC:4.2.1.33 4.2.1.35]
101250813  3-isopropylmalate dehydratase small subunit 3 [KO:K01704] [EC:4.2.1.33 4.2.1.35]
101247914  3-isopropylmalate dehydrogenase, chloroplastic [KO:K00052] [EC:1.1.1.85]
101247891  acetolactate synthase 2, chloroplastic [KO:K01652] [EC:2.2.1.6]
101268696  acetolactate synthase 1, chloroplastic-like [KO:K01652] [EC:2.2.1.6]
101254112  acetolactate synthase 2, chloroplastic-like [KO:K01652] [EC:2.2.1.6]
101265999  acetolactate synthase small subunit 1, chloroplastic [KO:K01653] [EC:2.2.1.6]
101252944  acetolactate synthase small subunit 1, chloroplastic [KO:K01653] [EC:2.2.1.6]
101257242  ketol-acid reductoisomerase, chloroplastic-like [KO:K00053] [EC:1.1.1.86]
101261134  ketol-acid reductoisomerase, chloroplastic [KO:K00053] [EC:1.1.1.86]
101246533  dihydroxy-acid dehydratase, chloroplastic [KO:K01687] [EC:4.2.1.9]
101264707  dihydroxy-acid dehydratase-like [KO:K01687] [EC:4.2.1.9]
101261313  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
101245812  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
101251085  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
101253875  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
101265804  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
101254608  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
101245066  2-isopropylmalate synthase B [KO:K01649] [EC:2.3.3.13]
101251907  IPMS2; isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
101252796  2-isopropylmalate synthase A-like [KO:K01649] [EC:2.3.3.13]
104648641  2-isopropylmalate synthase A-like [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
sly00260  Glycine, serine and threonine metabolism
sly00280  Valine, leucine and isoleucine degradation
sly00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

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