KEGG   PATHWAY: smel00350
Entry
smel00350                   Pathway                                
Name
Tyrosine metabolism - Sinorhizobium meliloti 2011
Class
Metabolism; Amino acid metabolism
Pathway map
smel00350  Tyrosine metabolism
smel00350

Module
smel_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:smel00350]
Other DBs
GO: 0006570
Organism
Sinorhizobium meliloti 2011 [GN:smel]
Gene
SM2011_c04386  aatB; Aspartate aminotransferase B [KO:K00812] [EC:2.6.1.1]
SM2011_c01578  aatA; Aspartate aminotransferase A (transaminase) [KO:K00812] [EC:2.6.1.1]
SM2011_c02393  hisC4; putative histidinol-phosphate aminotransferase [KO:K00817] [EC:2.6.1.9]
SM2011_c03885  hisC2; Putative histidinol-phosphate aminotransferase [KO:K00817] [EC:2.6.1.9]
SM2011_a0387  hisC3; Histidinol-phosphate aminotransferase [KO:K00817] [EC:2.6.1.9]
SM2011_c00710  hisC1; Putative histidinol-phosphate aminotransferase [KO:K00817] [EC:2.6.1.9]
SM2011_c00387  putative aspartate/tyrosine/aromatic aminotransferase [KO:K00832] [EC:2.6.1.57]
SM2011_c03211  Putative 4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
SM2011_c03208  hmgA; Homogentisate 1,2-dioxygenase [KO:K00451] [EC:1.13.11.5]
SM2011_c03206  maiA; Maleylacetoacetate isomerase (glutathione transferase zeta 1) protein [KO:K01800] [EC:5.2.1.2]
SM2011_c03207  hypothetical protein [KO:K16171] [EC:3.7.1.2]
SM2011_c01270  adhC1; putative alcohol dehydrogenase class III + glutathione-dependent formaldehyde dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
SM2011_a2113  adhC2; AdhC2 glutathione-dependent dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
SM2011_b20170  putative S-(hydroxymethyl)glutathione dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
SM2011_a1296  adhA1; Alcohol dehydrogenase,Zn-dependent class III [KO:K13953] [EC:1.1.1.1]
SM2011_c00105  putative alcohol dehydrogenase [KO:K00001] [EC:1.1.1.1]
SM2011_c03929  Putative zinc-type alcohol dehydrogenase transmembrane protein
SM2011_c02778  hpcH; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [KO:K02510] [EC:4.1.2.52]
SM2011_b21185  gabD2; Putative succinate-semialdehyde dehydrogenase (NAD(P)+) protein [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
SM2011_a0260  gabD3; GabD3 succinate-semialdehyde dehdyrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
SM2011_a0805  gabD4; GabD4 succinate-semialdehyde dehdyrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
SM2011_b20378  Succinate-semialdehyde dehydrogenase [NAD(P)+] [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
SM2011_a1848  gabD5; GabD5 succinate semialdehyde dehdyrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
SM2011_c02780  gabD1; putative succinate-semialdehyde dehydrogenase [NADP+] protein [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
SM2011_c04240  hypothetical protein [KO:K16165] [EC:3.7.1.20]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
smel00020  Citrate cycle (TCA cycle)
smel00360  Phenylalanine metabolism
smel00400  Phenylalanine, tyrosine and tryptophan biosynthesis
smel00620  Pyruvate metabolism
smel00650  Butanoate metabolism
KO pathway
ko00350   
LinkDB

DBGET integrated database retrieval system