KEGG   PATHWAY: sso00290
Entry
sso00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Saccharolobus solfataricus P2
Class
Metabolism; Amino acid metabolism
Pathway map
sso00290  Valine, leucine and isoleucine biosynthesis
sso00290

Module
sso_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sso00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Saccharolobus solfataricus P2 [GN:sso]
Gene
SSO0127  leuA-1; 2-isopropylmalate synthase, putative (leuA-1) [KO:K01649] [EC:2.3.3.13]
SSO0248  tdcB; Threonine dehydratase catabolic (threonine deaminase) (tdcB) [KO:K01754] [EC:4.3.1.19]
SSO0576  ilvC-1; Ketol-acid reductoisomerase (ilvC-1) [KO:K00053] [EC:1.1.1.86]
SSO0579  ilvB-2; Acetolactate synthase large subunit homolog (ilvB-2) [KO:K01652] [EC:2.2.1.6]
SSO0723  leuB; 3-isopropylmalate dehydrogenase (leuB) [KO:K00052] [EC:1.1.1.85]
SSO0977  leuA-2; 2-isopropylmalate synthase (leuA-2) [KO:K01649] [EC:2.3.3.13]
SSO1322  ilvC-2; Ketol-acid reductoisomerase (ilvC-2) [KO:K00053] [EC:1.1.1.86]
SSO1942  ilvC-3; Ketol-acid reductoisomerase (ilvC-3) [KO:K00053] [EC:1.1.1.86]
SSO2407  leuA-3; 2-isopropylmalate synthase, putative (leuA-3) [KO:K01649] [EC:2.3.3.13]
SSO2470  leuD; 3-isopropylmalate dehydratase, small subunit (isopropylmalate isomerase) (alpha IPM isomerase) (IPMI) (leuD) [KO:K01704] [EC:4.2.1.33 4.2.1.35]
SSO2471  leuC; 3-isopropylmalate dehydratase, large subunit (isopropylmalate isomerase) (alpha IPM isomerase) (IPMI) (leuC) [KO:K01703] [EC:4.2.1.33 4.2.1.35]
SSO3107  ilvD; Dihydroxy-acid dehydratase (ilvD) [KO:K01687] [EC:4.2.1.9]
SSO3210  ilvB-6; Acetolactate synthase large subunit homolog (ilvB-6) [KO:K01652] [EC:2.2.1.6]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
sso00260  Glycine, serine and threonine metabolism
sso00280  Valine, leucine and isoleucine degradation
sso00620  Pyruvate metabolism
KO pathway
ko00290   

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