Entry Name ABC transporters - Yersinia pestis Harbin35
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Other DBs Organism Yersinia pestis Harbin35 [GN:
ypj ]
Gene CH55_1213 potH; putrescine transport system permease protein PotH [KO:K11075 ]
CH55_1274 yejB; inner membrane ABC transporter permease protein yejB [KO:K13894 ]
CH55_1275 yejE; inner membrane ABC transporter permease protein yejE [KO:K13895 ]
CH55_1362 phnE; phosphonate ABC transporter, permease protein PhnE [KO:K02042 ]
CH55_1364 phnE; phosphonate ABC transporter, permease protein PhnE [KO:K02042 ]
CH55_1365 phnD; phosphonate ABC transporter, periplasmic phosphonate binding protein [KO:K02044 ]
CH55_1722 mdlB; multidrug resistance-like ATP-binding protein MdlB [KO:K18890 ]
CH55_1778 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
CH55_1970 fhuB; iron(3+)-hydroxamate import system permease protein fhuB [KO:K23228 ]
CH55_201 lolC; lipo-releasing system transmembrane protein lolC [KO:K09808 ]
CH55_202 lolD; liporeleasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
CH55_203 lolE; liporeleasing system, transmembrane protein LolE [KO:K09808 ]
CH55_2264 thiP; thiamine/thiamine pyrophosphate ABC transporter, permease protein [KO:K02063 ]
CH55_2265 thiB; thiamin/thiamine pyrophosphate ABC transporter, thiamin/thiamine pyrophospate-binding protein [KO:K02064 ]
CH55_2485 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
CH55_2716 xylF; D-xylose ABC transporter, D-xylose-binding protein [KO:K10543 ]
CH55_274 oppB; oligopeptide transport system permease protein oppB [KO:K15581 ]
CH55_275 oppC; oligopeptide transport system permease protein oppC [KO:K15582 ]
CH55_2797 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
CH55_2798 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
CH55_2799 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
CH55_2848 malK; maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
CH55_2922 tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
CH55_3104 ytfQ; ABC transporter periplasmic-binding protein ytfQ [KO:K23508 ]
CH55_3208 livH; high-affinity branched-chain amino acid transport system permease protein livH [KO:K01997 ]
CH55_3211 livF; high-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
CH55_35 hisM; histidine transport system permease protein hisM [KO:K10015 ]
CH55_3823 metI; D-methionine transport system permease protein metI [KO:K02072 ]
CH55_3824 metN; D-methionine ABC transporter, ATP-binding protein [KO:K02071 ]
CH55_3905 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
CH55_3986 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
CH55_432 sapB; peptide transport system permease protein sapB [KO:K19227 ]
CH55_433 sapC; peptide transport system permease protein sapC [KO:K19228 ]
CH55_435 sapF; peptide transport system ATP-binding protein SapF [KO:K19230 ]
CH55_828 yecS; inner membrane amino-acid ABC transporter permease protein yecS [KO:K10009 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway
