Protein Kinases

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 Serine/threonine kinases: AGC group

 

 Serine/threonine kinases: CAMK group

 

 Serine/threonine kinases: CK1 group

 

 Serine/threonine kinases: CMGC group

 

 Serine/threonine kinases: STE group

 

 Serine/threonine kinases: TKL group

 

 Serine/threonine kinases: Other

 

 Receptor serine/threonine kinases (RSTK): TKL group

 

 Receptor tyrosine kinases (RTK)

 

 Non-receptor tyrosine kinases

 

 Histidine kinases

   OmpR family

     K07636  phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
     K07768  senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
     K07637  phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
     K07638  envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
     K07639  rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
     K07640  cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
     K07650  cssS; two-component system, OmpR family, sensor histidine kinase CssS [EC:2.7.13.3]
     K07641  creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
     K07642  baeS, smeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
     K07643  basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]
     K07644  cusS, copS, silS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
     K07645  qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
     K07646  kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
     K07647  torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]
     K07648  arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
     K07649  tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
     K07651  resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
     K07652  vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
     K07653  mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
     K07654  mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
     K07655  prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]
     K07656  trcS; two-component system, OmpR family, sensor histidine kinase TrcS [EC:2.7.13.3]
     K11328  nrsS, rppB; two-component system, OmpR family, Ni(II)-sensor and/or redox sensor kinase NrsS [EC:2.7.13.3]
     K11520  manS; two-component system, OmpR family, manganese sensing sensor histidine kinase [EC:2.7.13.3]
     K07769  nblS, dfr, dspA, hik33; two-component system, OmpR family, sensor histidine kinase NblS [EC:2.7.13.3]
     K08479  sasA; two-component system, OmpR family, clock-associated histidine kinase SasA [EC:2.7.13.3]
     K10681  saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]
     K11629  bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]
     K19077  graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3]
     K19081  braS, bceS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3]
     K11633  yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]
     K14980  chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
     K14982  ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
     K18072  parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
     K18143  adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]
     K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
     K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
     K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
     K18940  arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
     K18986  ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
     K19609  pfeS, pirS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3]
     K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3]
     K02484  K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]

   NarL family

   Spo family [OT]

   CitB family [OT]

   LytTR family [OT]

   NtrC family

   CheA family [OT]

   Cell cycle family [OT]

   Lux family [OT]

   LuxR family [OT]

   Other

     K10942  flrB, fleS, flaL; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
     K11231  SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
     K19690  CHK1; osomolarity two-component system, sensor histidine kinase CHK1 [EC:2.7.13.3]
     K19691  NIK1, TCSC; osomolarity two-component system, sensor histidine kinase NIK1 [EC:2.7.13.3]
     K19692  TCSA; osomolarity two-component system, sensor histidine kinase TcsA [EC:2.7.13.3]
     K10715  rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
     K07717  glnK; two-component system, sensor histidine kinase GlnK [EC:2.7.13.3]
     K25212  hptS; two-component system, sensor histidine kinase HptS [EC:2.7.13.3]
     K07718  yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
     K11356  cikA; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
     K15011  regB, regS, actS; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
     K19616  fitF; two-component system, sensor histidine kinase and response regulator FitF [EC:2.7.13.3]
     K19621  phcS; two-component system, sensor histidine kinase PhcS [EC:2.7.13.3]
     K20973  sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
     K20974  K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
     K20975  K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
     K00936  pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
     K19694  chiS; two-component system, sensor histidine kinase ChiS
     K20971  ladS; two-component system, sensor histidine kinase LadS
     K20972  retS; two-component system, sensor histidine kinase RetS
     K02486  K02486; two-component system, sensor kinase [EC:2.7.13.3]
     K11527  K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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Last updated: February 5, 2025
Classification taken and modified from Hanks (2003)