KEGG   PATHWAY: amex00330
Entry
amex00330                   Pathway                                
Name
Arginine and proline metabolism - Astyanax mexicanus (Mexican tetra)
Class
Metabolism; Amino acid metabolism
Pathway map
amex00330  Arginine and proline metabolism
amex00330

Module
amex_M00015  Proline biosynthesis, glutamate => proline [PATH:amex00330]
amex_M00047  Creatine pathway [PATH:amex00330]
amex_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:amex00330]
amex_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:amex00330]
amex_M00970  Proline degradation, proline => glutamate [PATH:amex00330]
amex_M00972  Proline metabolism [PATH:amex00330]
Other DBs
GO: 0006525 0006560
Organism
Astyanax mexicanus (Mexican tetra) [GN:amex]
Gene
103044592  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
103023041  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
103027016  creatine kinase B-type-like [KO:K00933] [EC:2.7.3.2]
103038758  creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
103022288  creatine kinase U-type, mitochondrial-like [KO:K00933] [EC:2.7.3.2]
103024445  creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
103021922  creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
103044128  creatine kinase M-type [KO:K27382] [EC:2.7.3.2]
103045415  creatine kinase M-type [KO:K27382] [EC:2.7.3.2]
103031433  creatine kinase, testis isozyme-like [KO:K27382] [EC:2.7.3.2]
103026254  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
103022244  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
103023143  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
103033968  amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
103033242  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
103027240  peroxisomal N(1)-acetyl-spermine/spermidine oxidase-like isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
103026971  spermine oxidase-like [KO:K12259] [EC:1.5.3.16 1.5.3.-]
103028620  smox; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
103026903  fatty aldehyde dehydrogenase-like [KO:K00128] [EC:1.2.1.3]
103027191  LOW QUALITY PROTEIN: aldehyde dehydrogenase, dimeric NADP-preferring [KO:K00128] [EC:1.2.1.3]
103043579  fatty aldehyde dehydrogenase-like [KO:K00128] [EC:1.2.1.3]
103029711  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
103036383  aldh2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
103034062  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
103023076  aldh9a1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
103024590  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
103030130  diamine acetyltransferase 1-like [KO:K00657] [EC:2.3.1.57]
103043715  diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
103025143  diamine acetyltransferase 1-like [KO:K00657] [EC:2.3.1.57]
103033722  maob; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
103039919  probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
103044008  agmat; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
103046065  nos1; LOW QUALITY PROTEIN: nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
103031688  nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
103026958  nitric oxide synthase, inducible-like isoform X1 [KO:K13241] [EC:1.14.13.39]
103044486  arg1; arginase-1 [KO:K01476] [EC:3.5.3.1]
103042158  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
103043166  oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
103037533  pycr3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
103031810  pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
103042105  proline dehydrogenase 1, mitochondrial-like [KO:K00318] [EC:1.5.5.2]
103035900  LOW QUALITY PROTEIN: proline dehydrogenase 1, mitochondrial-like [KO:K00318] [EC:1.5.5.2]
103033203  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
103029980  aldh18a1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
103025918  lap3; cytosol aminopeptidase isoform X1 [KO:K11142] [EC:3.4.11.1 3.4.11.5]
103044793  p4ha1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
103029151  prolyl 4-hydroxylase subunit alpha-1-like [KO:K00472] [EC:1.14.11.2]
103035586  prolyl 4-hydroxylase subunit alpha-2-like [KO:K00472] [EC:1.14.11.2]
103035211  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
103026899  prolyl 4-hydroxylase subunit alpha-1-like isoform X1 [KO:K00472] [EC:1.14.11.2]
103022862  prodh2; LOW QUALITY PROTEIN: hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
103047857  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
103034654  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
103034182  got2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
103023796  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
103023242  dao; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
103042342  l3hypdh; trans-3-hydroxy-L-proline dehydratase isoform X2 [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
amex00020  Citrate cycle (TCA cycle)
amex00220  Arginine biosynthesis
amex00250  Alanine, aspartate and glutamate metabolism
amex00260  Glycine, serine and threonine metabolism
amex00270  Cysteine and methionine metabolism
amex00310  Lysine degradation
amex00410  beta-Alanine metabolism
amex00470  D-Amino acid metabolism
amex00480  Glutathione metabolism
amex00630  Glyoxylate and dicarboxylate metabolism
amex00650  Butanoate metabolism
amex00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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