KEGG   PATHWAY: csyr05163
Entry
csyr05163                   Pathway                                
Name
Human cytomegalovirus infection - Carlito syrichta (Philippine tarsier)
Description
Human cytomegalovirus (HCMV) is an enveloped, double-stranded DNA virus that is a member of beta-herpesvirus family. HCMV is best known for causing significant morbidity and mortality in immunocompromised populations. As with other herpesviruses, HCMV gB and gH/gL envelope glycoproteins are essential for virus entry. HCMV gB could activate the PDGFRA, and induce activation of the oncogenic PI3-K/AKT pathway. Though it is unlikely that HCMV by itself can act as an oncogenic factor, HCMV may have an oncomodulatory role, to catalyze an oncogenic process that has already been initiated. US28, one of the four HCMV-encoded vGPCRs (US27, US28, UL33 and UL78), also has a specific role in the oncomodulatory properties. In addition, HCMV has developed numerous mechanisms for manipulating the host immune system. The virally encoded US2, US3, US6 and US11 gene products all interfere with major histocompatibility complex (MHC) class I antigen presentation. HCMV encodes several immediate early (IE) antiapoptotic proteins (IE1, IE2, vMIA and vICA). These proteins might avoid immune clearance of infected tumor cells by cytotoxic lymphocytes and NK cells.
Class
Human Diseases; Infectious disease: viral
Pathway map
csyr05163  Human cytomegalovirus infection
csyr05163

Organism
Carlito syrichta (Philippine tarsier) [GN:csyr]
Gene
103249185  PDGFRA; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
103251553  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
103266233  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
103276054  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2 [KO:K00922] [EC:2.7.1.153]
103262537  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2 [KO:K02649]
103272136  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2 [KO:K02649]
103257728  AKT1; LOW QUALITY PROTEIN: RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
103254239  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
103263958  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
103250930  TSC1; hamartin isoform X1 [KO:K07206]
103250119  TSC2; LOW QUALITY PROTEIN: tuberin [KO:K07207]
103270389  LOW QUALITY PROTEIN: GTP-binding protein Rheb-like [KO:K07208]
103272783  LOW QUALITY PROTEIN: GTP-binding protein Rheb-like [KO:K07208]
103275306  RHEB; GTP-binding protein Rheb [KO:K07208]
103272291  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
103251539  RPS6KB2; ribosomal protein S6 kinase beta-2 [KO:K04688] [EC:2.7.11.1]
103273417  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
103263189  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
103256847  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
103255498  IKBKG; NF-kappa-B essential modulator [KO:K07210]
103274648  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
103252103  RELA; transcription factor p65 [KO:K04735]
103268107  EGFR; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
103275922  GRB2; growth factor receptor-bound protein 2 isoform X1 [KO:K04364]
103270607  SOS1; son of sevenless homolog 1 isoform X1 [KO:K03099]
103276422  SOS2; son of sevenless homolog 2 isoform X2 [KO:K03099]
103250130  HRAS; GTPase HRas isoform X1 [KO:K02833]
103263630  KRAS; GTPase KRas isoform X2 [KO:K07827]
103259236  NRAS; GTPase NRas [KO:K07828]
103263745  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X3 [KO:K04366] [EC:2.7.11.1]
103277453  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
103251709  dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
103265435  MAPK1; mitogen-activated protein kinase 1 isoform X1 [KO:K04371] [EC:2.7.11.24]
103274188  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
103270864  ELK1; ETS domain-containing protein Elk-1 isoform X1 [KO:K04375]
103260226  transcription factor Sp1 [KO:K04684]
103268155  ITGAV; integrin alpha-V [KO:K06487]
103273857  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
103264336  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
103273938  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
103258883  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
103251325  RAC3; ras-related C3 botulinum toxin substrate 3 [KO:K07861]
103250976  RHOA; transforming protein RhoA isoform X1 [KO:K04513]
103253660  transforming protein RhoA-like [KO:K04513]
103258632  MB21D1; cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
103249555  TMEM173; stimulator of interferon genes protein [KO:K12654]
103271912  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
103249777  IRF3; interferon regulatory factor 3 isoform X2 [KO:K05411]
103260907  interferon alpha-5-like [KO:K05414]
103260908  interferon alpha-5-like [KO:K05414]
103260910  interferon alpha-5-like [KO:K05414]
103274154  interferon alpha-5-like [KO:K05414]
103274155  interferon alpha-5-like [KO:K05414]
103274156  interferon alpha-10-like [KO:K05414]
103274157  interferon alpha-17-like [KO:K05414]
103274161  interferon alpha-5-like [KO:K05414]
103274163  interferon alpha-17-like [KO:K05414]
103274165  interferon alpha-5-like [KO:K05414]
103274168  interferon alpha-5-like [KO:K05414]
103260915  IFNB1; interferon beta [KO:K05415]
103270149  TNF; tumor necrosis factor [KO:K03156]
103250566  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
103272007  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
103269228  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2 [KO:K03171]
103260228  TRAF5; TNF receptor-associated factor 5 isoform X2 [KO:K09849]
103252426  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
103259440  IL1B; interleukin-1 beta [KO:K04519]
103260528  IL1R1; interleukin-1 receptor type 1 [KO:K04386]
103273993  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
103264824  C-C motif chemokine 2 [KO:K14624]
103265808  CCL5; C-C motif chemokine 5 [KO:K12499]
103266387  interleukin-8-like [KO:K10030]
103259317  CXCL8; interleukin-8 [KO:K10030]
103268608  IL6; interleukin-6 [KO:K05405]
103251518  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1 [KO:K04536]
103255674  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X3 [KO:K04537]
103265017  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1 [KO:K07825]
103262814  GNB4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538]
103275187  GNB5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539]
103273050  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 isoform X1 [KO:K07826]
103255636  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
103254833  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
110594660  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
110594775  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
110594710  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
110595842  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
103268263  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
103271375  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
110595573  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
110596243  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
103271374  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
110596118  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
103258399  guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
103252789  guanine nucleotide-binding protein subunit alpha-11 [KO:K04635]
103261218  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
103257479  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
103272341  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
103275147  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
103256992  inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
103261167  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
103269243  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
103250483  calmodulin-like isoform X3 [KO:K02183]
103255950  calmodulin-like [KO:K02183]
103257967  calmodulin-like [KO:K02183]
103252808  calmodulin isoform X1 [KO:K02183]
103261438  calmodulin-like [KO:K02183]
103264241  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
103274844  CALML6; calmodulin-like protein 6 [KO:K02183]
103268605  calmodulin isoform X3 [KO:K02183]
103263669  PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
103265906  PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
103266637  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
110595246  PPP3R1; calcineurin subunit B type 1 [KO:K06268]
103255431  PPP3R2; calcineurin subunit B type 2 [KO:K06268]
103266669  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 [KO:K04446]
103276035  NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
103268196  NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
103272225  NFATC4; nuclear factor of activated T-cells, cytoplasmic 4 isoform X1 [KO:K17334]
103275362  PTGS2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
103263431  GNAI3; guanine nucleotide-binding protein G(k) subunit alpha [KO:K04630]
103255466  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1 [KO:K04630]
103264772  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
103253155  GNAO1; guanine nucleotide-binding protein G(o) subunit alpha [KO:K04534]
103252919  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
103262642  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
103272228  ADCY4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
103254816  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
103273462  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
103259338  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
103267869  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
103273680  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
103253311  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2 [KO:K04345] [EC:2.7.11.11]
103266092  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
103271195  C-C motif chemokine 3-like [KO:K05408]
103254389  C-C motif chemokine 4 isoform X1 [KO:K12964]
103270507  CX3CL1; fractalkine isoform X2 [KO:K05508]
103254023  GNA12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
103260636  GNA13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639]
103273601  ARHGEF1; rho guanine nucleotide exchange factor 1 [KO:K12330]
103251206  ARHGEF11; rho guanine nucleotide exchange factor 11 [KO:K12331]
103261835  ARHGEF12; rho guanine nucleotide exchange factor 12 [KO:K07532]
103266097  AKAP13; A-kinase anchor protein 13 isoform X2 [KO:K16529]
103272758  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
103267985  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
103258755  CTNNB1; catenin beta-1 isoform X1 [KO:K02105]
103254433  PTGER4; prostaglandin E2 receptor EP4 subtype [KO:K04261]
103251768  neuroendocrine secretory protein 55 [KO:K04632]
103255823  guanine nucleotide-binding protein G(s) subunit alpha isoform X1 [KO:K04632]
103258382  GSK3B; glycogen synthase kinase-3 beta [KO:K03083] [EC:2.7.11.26]
103252197  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
103264057  MYC; myc proto-oncogene protein [KO:K04377]
103249543  IL6R; interleukin-6 receptor subunit alpha [KO:K05055]
103262860  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
103273032  signal transducer and activator of transcription 3 [KO:K04692]
103267743  STAT3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 3 [KO:K04692]
103277171  LOW QUALITY PROTEIN: signal transducer and activator of transcription 3-like [KO:K04692]
103262949  VEGFA; vascular endothelial growth factor A isoform X2 [KO:K05448]
103254297  LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
103249454  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
103249455  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
103263392  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
103263391  MAPK14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
103252293  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
103264952  ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
103267309  ATF4; cyclic AMP-dependent transcription factor ATF-4 isoform X2 [KO:K04374]
103249547  CREB3L3; LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 3 [KO:K09048]
103252136  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
103263755  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
103265465  CREB3; cyclic AMP-responsive element-binding protein 3 isoform X1 [KO:K09048]
103257302  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
103273492  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X2 [KO:K09047]
103271306  ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta isoform X3 [KO:K09049]
103269764  stromal cell-derived factor 1-like [KO:K10031]
103277206  stromal cell-derived factor 1-like [KO:K10031]
103273984  CXCR4; C-X-C chemokine receptor type 4 isoform X2 [KO:K04189]
103269994  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
103251444  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
103276479  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
103251411  PTK2B; protein-tyrosine kinase 2-beta isoform X1 [KO:K05871] [EC:2.7.10.2]
103249709  PTK2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
103251606  BCAR1; breast cancer anti-estrogen resistance protein 1 [KO:K05726]
103271341  CRKL; crk-like protein [KO:K04438]
103275951  CRK; adapter molecule crk isoform X1 [KO:K04438]
103271808  PXN; LOW QUALITY PROTEIN: paxillin [KO:K05760]
103255683  IL10RA; interleukin-10 receptor subunit alpha [KO:K05134]
103269358  IL10RB; LOW QUALITY PROTEIN: interleukin-10 receptor subunit beta [KO:K05135]
103276381  C-X-C chemokine receptor type 2-like [KO:K05050]
103276389  C-X-C chemokine receptor type 2-like [KO:K05050]
103265359  CCR1; C-C chemokine receptor type 1 [KO:K04176]
103273775  CCR3; C-C chemokine receptor type 3 [KO:K04178]
103273777  CCR5; C-C chemokine receptor type 5 [KO:K04180]
103271934  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
103271932  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
103262563  TAPBP; tapasin [KO:K08058]
103262024  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
103249397  CALR; calreticulin [KO:K08057]
103269400  calreticulin-like [KO:K08057]
103251393  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like [KO:K06751]
103273534  HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
103268467  patr class I histocompatibility antigen, B-2 alpha chain-like isoform X1 [KO:K06751]
103271436  HLA class I histocompatibility antigen, A-11 alpha chain-like [KO:K06751]
103273536  HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
103276998  HLA class I histocompatibility antigen, B-37 alpha chain-like [KO:K06751]
103277080  HLA class I histocompatibility antigen, A-23 alpha chain-like [KO:K06751]
103254879  B2M; beta-2-microglobulin [KO:K08055]
103259932  cyclin-dependent kinase inhibitor 2A [KO:K06621]
103250373  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
103264637  TP53; cellular tumor antigen p53 [KO:K04451]
103266974  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
103264423  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
103276439  cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
103259274  RB1; retinoblastoma-associated protein [KO:K06618]
103253965  E2F1; transcription factor E2F1 [KO:K17454]
103264171  E2F2; transcription factor E2F2 [KO:K09389]
103260979  E2F3; transcription factor E2F3 [KO:K06620]
103273211  FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
103273943  FAS; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
103262441  FADD; FAS-associated death domain protein [KO:K02373]
103273365  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
103274231  BID; BH3-interacting domain death agonist [KO:K04726]
103256231  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
103262464  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
103255326  cytochrome c 2 [KO:K08738]
110596190  cytochrome c, somatic-like [KO:K08738]
103274909  cytochrome c, somatic [KO:K08738]
103260483  CASP9; caspase-9 [KO:K04399] [EC:3.4.22.62]
103257846  caspase-3 [KO:K02187] [EC:3.4.22.56]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00584  Prostaglandin E2
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
Reference
PMID:19107226
  Authors
Michaelis M, Doerr HW, Cinatl J
  Title
The story of human cytomegalovirus and cancer: increasing evidence and open questions.
  Journal
Neoplasia 11:1-9 (2009)
DOI:10.1593/neo.81178
Reference
PMID:24839861
  Authors
Roy S, Arav-Boger R
  Title
New cell-signaling pathways for controlling cytomegalovirus replication.
  Journal
Am J Transplant 14:1249-58 (2014)
DOI:10.1111/ajt.12725
Reference
PMID:14720582
  Authors
Cinatl J, Scholz M, Kotchetkov R, Vogel JU, Doerr HW
  Title
Molecular mechanisms of the modulatory effects of HCMV infection in tumor cell biology.
  Journal
Trends Mol Med 10:19-23 (2004)
DOI:10.1016/j.molmed.2003.11.002
Reference
PMID:15380778
  Authors
Evers DL, Wang X, Huang ES
  Title
Cellular stress and signal transduction responses to human cytomegalovirus infection.
  Journal
Microbes Infect 6:1084-93 (2004)
DOI:10.1016/j.micinf.2004.05.026
Reference
PMID:29547547
  Authors
Murray MJ, Peters NE, Reeves MB
  Title
Navigating the Host Cell Response during Entry into Sites of Latent Cytomegalovirus Infection.
  Journal
Pathogens 7:E30 (2018)
DOI:10.3390/pathogens7010030
Reference
PMID:27501260
  Authors
Campadelli-Fiume G, Collins-McMillen D, Gianni T, Yurochko AD
  Title
Integrins as Herpesvirus Receptors and Mediators of the Host Signalosome.
  Journal
Annu Rev Virol 3:215-236 (2016)
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Related
pathway
csyr00590  Arachidonic acid metabolism
csyr03050  Proteasome
csyr04010  MAPK signaling pathway
csyr04064  NF-kappa B signaling pathway
csyr04110  Cell cycle
csyr04150  mTOR signaling pathway
csyr04151  PI3K-Akt signaling pathway
csyr04210  Apoptosis
csyr04612  Antigen processing and presentation
csyr04623  Cytosolic DNA-sensing pathway
csyr04630  JAK-STAT signaling pathway
csyr04668  TNF signaling pathway
csyr04810  Regulation of actin cytoskeleton
KO pathway
ko05163   
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