KEGG   PATHWAY: lmut05132
Entry
lmut05132                   Pathway                                
Name
Salmonella infection - Lagopus muta (rock ptarmigan)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
lmut05132  Salmonella infection
lmut05132

Organism
Lagopus muta (rock ptarmigan) [GN:lmut]
Gene
125701565  PODXL; podocalyxin isoform X1 [KO:K06817]
125694203  PTPRC; receptor-type tyrosine-protein phosphatase C isoform X1 [KO:K06478] [EC:3.1.3.48]
125695933  RAB5A; ras-related protein Rab-5A [KO:K07887]
125685546  RAB5B; ras-related protein Rab-5B [KO:K07888]
125684583  RAB5C; ras-related protein Rab-5C [KO:K07889]
125687152  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
125698617  RAB7A; ras-related protein Rab-7a [KO:K07897]
125684184  RAB7B; ras-related protein Rab-7b isoform X1 [KO:K07898]
125684597  PLEKHM1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
125703598  VPS11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
125691832  VPS16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
125694915  VPS18; vacuolar protein sorting-associated protein 18 homolog isoform X1 [KO:K20181]
125701759  VPS33A; vacuolar protein sorting-associated protein 33A [KO:K20182]
125694406  VPS39; vam6/Vps39-like protein isoform X1 [KO:K20183]
125695762  VPS41; vacuolar protein sorting-associated protein 41 homolog isoform X1 [KO:K20184]
125702890  rab-interacting lysosomal protein [KO:K13883]
125695571  DYNC1H1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
125689216  DYNC2H1; cytoplasmic dynein 2 heavy chain 1 isoform X1 [KO:K10414]
125696488  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 isoform X1 [KO:K10415]
125696630  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
125688220  cytoplasmic dynein 1 intermediate chain 2-like [KO:K10415]
125695754  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 isoform X1 [KO:K10416]
125699133  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 [KO:K10416]
125688612  DYNC2LI1; cytoplasmic dynein 2 light intermediate chain 1 isoform X1 [KO:K10417]
125701903  dynein light chain 1, cytoplasmic [KO:K10418]
125701907  dynein light chain 2, cytoplasmic-like [KO:K10418]
125701910  dynein light chain 1, cytoplasmic-like [KO:K10418]
125701911  dynein light chain LC6, flagellar outer arm-like [KO:K10418]
125702969  DYNLL2; dynein light chain 2, cytoplasmic [KO:K10418]
125699480  DYNLRB2; dynein light chain roadblock-type 2 [KO:K10419]
125701233  dynein light chain roadblock-type 1-like isoform X1 [KO:K10419]
125701236  dynein light chain roadblock-type 1-like isoform X1 [KO:K10419]
125701237  dynein light chain roadblock-type 1-like isoform X1 [KO:K10419]
125689712  DYNLT1; dynein light chain Tctex-type 1 isoform X1 [KO:K10420]
125703945  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
125691830  DCTN1; dynactin subunit 1 isoform X1 [KO:K04648]
125687148  DCTN3; dynactin subunit 3 [KO:K10425]
125700100  DCTN4; dynactin subunit 4 isoform X1 [KO:K10426]
125700731  DCTN5; dynactin subunit 5 [KO:K10427]
125691550  DCTN6; dynactin subunit 6 [KO:K10428]
125693234  ACTR1A; alpha-centractin [KO:K16575]
125695454  alpha-centractin-like [KO:K16575]
125695037  ACTR10; actin-related protein 10 isoform X1 [KO:K16576]
125696133  tubulin alpha-3 chain-like isoform X1 [KO:K07374]
125696682  tubulin alpha-5 chain [KO:K07374]
125696683  tubulin alpha-4A chain-like [KO:K07374]
125684231  tubulin alpha-8 chain [KO:K07374]
125703037  tubulin alpha-4 chain [KO:K07374]
125703045  tubulin alpha-2 chain [KO:K07374]
125691281  tubulin alpha-3 chain-like isoform X1 [KO:K07374]
125691282  tubulin alpha-3 chain-like isoform X1 [KO:K07374]
125691283  tubulin alpha-3 chain-like isoform X1 [KO:K07374]
125691285  tubulin alpha-8 chain-like [KO:K07374]
125697691  tubulin alpha-3 chain-like [KO:K07374]
125685354  tubulin alpha-1A chain [KO:K07374]
125685355  TUBA1B; tubulin alpha-1B chain [KO:K07374]
125685356  LOW QUALITY PROTEIN: tubulin alpha-1C chain-like [KO:K07374]
125692253  tubulin alpha-3 chain [KO:K07374]
125685982  tubulin alpha-3 chain-like isoform X1 [KO:K07374]
125685990  tubulin alpha-3 chain-like [KO:K07374]
125685992  tubulin alpha-3 chain-like [KO:K07374]
125685994  tubulin alpha-3 chain-like [KO:K07374]
125686001  tubulin alpha-3 chain-like [KO:K07374]
125687306  tubulin alpha-3 chain-like [KO:K07374]
125688044  tubulin alpha-3 chain [KO:K07374]
125689344  LOW QUALITY PROTEIN: tubulin beta chain-like [KO:K07375]
125690320  tubulin beta-2 chain [KO:K07375]
125690321  tubulin beta-1 chain [KO:K07375]
125690611  TUBB6; tubulin beta-6 chain [KO:K07375]
125702684  TUBB4B; tubulin beta-4B chain [KO:K07375]
125699475  TUBB3; tubulin beta-3 chain [KO:K07375]
125701031  TUBB1; tubulin beta-1 chain isoform X1 [KO:K07375]
125695918  FYCO1; FYVE and coiled-coil domain-containing protein 1 isoform X1 [KO:K21954]
125684020  ARL8A; ADP-ribosylation factor-like protein 8A [KO:K07955]
125692370  ADP-ribosylation factor-like protein 8B isoform X1 [KO:K07955]
125698755  ARL8B; ADP-ribosylation factor-like protein 8B [KO:K07955]
125703318  PLEKHM2; pleckstrin homology domain-containing family M member 2 isoform X1 [KO:K15348]
125696513  KIF5B; kinesin-1 heavy chain isoform X1 [KO:K10396]
125697205  KIF5C; kinesin heavy chain isoform X1 [KO:K10396]
125688889  KLC4; kinesin light chain 4 isoform X1 [KO:K10407]
125695282  kinesin light chain 1 isoform X1 [KO:K10407]
125689849  ACBD3; Golgi resident protein GCP60 [KO:K23935]
125699000  RHOA; transforming protein RhoA [KO:K04513]
125687918  M6PR; cation-dependent mannose-6-phosphate receptor [KO:K10089]
125688481  RAB9A; ras-related protein Rab-9A [KO:K07899]
125699780  RAB9B; ras-related protein Rab-9B isoform X1 [KO:K07900]
125689131  GCC2; GRIP and coiled-coil domain-containing protein 2 [KO:K20282]
125690043  PFN3; profilin-3 [KO:K05759]
125697358  PFN2; profilin-2 isoform X1 [KO:K05759]
125702043  EXOC7; exocyst complex component 7 isoform X1 [KO:K07195]
125695558  EXOC5; exocyst complex component 5 isoform X1 [KO:K19984]
125702686  EXOC4; exocyst complex component 4 isoform X4 [KO:K06111]
125690630  EXOC2; exocyst complex component 2 [KO:K17637]
125696054  RALA; ras-related protein Ral-A [KO:K07834]
125702361  ACTG1; LOW QUALITY PROTEIN: actin, cytoplasmic 2 [KO:K05692]
125698094  actin, cytoplasmic type 5 [KO:K05692]
125700634  ACTB; actin, cytoplasmic 1 [KO:K05692]
125685672  S100A10; protein S100-A10 [KO:K17274]
125698033  ANXA2; annexin A2 [KO:K17092]
125687778  AHNAK; neuroblast differentiation-associated protein AHNAK isoform X1 [KO:K23934]
125694764  AHNAK2; protein AHNAK2 [KO:K23934]
125694428  RHOJ; rho-related GTP-binding protein RhoJ [KO:K07864]
125697308  ARHGEF26; rho guanine nucleotide exchange factor 26 [KO:K13744]
125695894  RHOG; rho-related GTP-binding protein RhoG [KO:K07863]
125699973  rho-related GTP-binding protein RhoG-like [KO:K07863]
125695632  ELMO1; engulfment and cell motility protein 1 isoform X1 [KO:K12366]
125701159  ELMO2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
125690189  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
125701687  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
125701342  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
125702923  MYL10; myosin regulatory light chain 10 isoform X1 [KO:K12756]
125690946  myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
125690947  myosin regulatory light chain 2, smooth muscle minor isoform-like [KO:K12757]
125699351  FHOD1; FH1/FH2 domain-containing protein 1 isoform X1 [KO:K23938]
125703287  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
125700553  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
125697027  NCKAP1; nck-associated protein 1 isoform X1 [KO:K05750]
125701599  CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749]
125700081  CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
125695879  ABI1; abl interactor 1 isoform X1 [KO:K23649]
125699001  BRK1; protein BRICK1 [KO:K05752]
125699950  wiskott-Aldrich syndrome protein family member 3-like isoform X1 [KO:K06083]
125688104  WASF3; wiskott-Aldrich syndrome protein family member 3 isoform X1 [KO:K06083]
125689069  ACTR2; actin-related protein 2 [KO:K17260]
125696183  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
125697100  ACTR3; actin-related protein 3 [KO:K18584]
125700767  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
125700859  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
125696679  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
125701763  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
125698741  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
125702439  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
125693836  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
125687950  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
125699845  PAK3; serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
125688969  MYO6; unconventional myosin-VI isoform X1 [KO:K10358]
125697457  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
125697863  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
125703469  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
125696977  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
125684198  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
125697629  PIK3C2G; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
125694485  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
125696075  CYTH4; cytohesin-4 [KO:K18441]
125702259  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
125700504  CYTH3; cytohesin-3 isoform X1 [KO:K18441]
125695116  ARF6; ADP-ribosylation factor 6 [KO:K07941]
125696221  ARF1; ADP-ribosylation factor 1 [KO:K07937]
125698348  SNX33; sorting nexin-33 [KO:K17923]
125686912  SNX18; sorting nexin-18 isoform X1 [KO:K17923]
125688793  SNX9; sorting nexin-9 isoform X1 [KO:K17923]
125691013  WASL; neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612]
125692111  toll-like receptor 1 [KO:K10169]
125691799  toll-like receptor 2 type-1 [KO:K10159]
125691800  TLR2; toll-like receptor 2 [KO:K10159]
125703751  toll/interleukin-1 receptor domain-containing adapter protein isoform X1 [KO:K05403]
125696192  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
125700313  CD14; monocyte differentiation antigen CD14 [KO:K04391]
125702708  TLR4; toll-like receptor 4 [KO:K10160]
125690384  LY96; lymphocyte antigen 96 [KO:K05400]
125690015  TLR5; toll-like receptor 5 isoform X1 [KO:K10168]
125688635  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
125694458  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
125689969  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
125698389  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
125689225  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
125686044  TAB3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
125693118  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
125685336  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
125695262  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
125691561  NFKB1; LOW QUALITY PROTEIN: nuclear factor NF-kappa-B p105 subunit [KO:K02580]
125696483  NOD1; nucleotide-binding oligomerization domain-containing protein 1 isoform X1 [KO:K08727]
125689413  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
125695572  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
125690016  HSP90B1; endoplasmin [KO:K09487]
125690619  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [KO:K08846] [EC:2.7.11.1]
125699214  uncharacterized protein LOC125699214 isoform X1 [KO:K08846] [EC:2.7.11.1]
125701199  CSE1L; exportin-2 [KO:K18423]
125688259  KPNA1; importin subunit alpha-5 [KO:K23940]
125697814  KPNA4; importin subunit alpha-3 [KO:K23583]
125701423  KPNA3; importin subunit alpha-4 isoform X1 [KO:K23583]
125695880  RPS3; 40S ribosomal protein S3 [KO:K02985]
125694448  HRAS; GTPase HRas [KO:K02833]
125698855  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
125698355  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
125684996  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
125701926  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
125700804  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
125702133  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
125684015  MAPK13; mitogen-activated protein kinase 13 isoform X1 [KO:K04441] [EC:2.7.11.24]
125684016  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
125691861  mitogen-activated protein kinase 11-like isoform X1 [KO:K04441] [EC:2.7.11.24]
125691943  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
125702281  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
125691554  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
125693785  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
125700042  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
125695245  FOS; protein c-Fos [KO:K04379]
125693900  JUN; transcription factor Jun [KO:K04448]
125685332  interleukin-1 beta-like isoform X1 [KO:K04519]
125695972  IL6; interleukin-6 [KO:K05405]
125692348  interleukin-8-like [KO:K10030]
125692349  interleukin-8 [KO:K10030]
125696039  CTNNB1; catenin beta-1 [KO:K02105]
125700061  TCF7; transcription factor 7 isoform X1 [KO:K02620]
125685234  TCF7L1; transcription factor 7-like 1 isoform X1 [KO:K04490]
125693546  TCF7L2; transcription factor 7-like 2 isoform X1 [KO:K04491]
125692117  LEF1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
125691213  MYC; myc proto-oncogene protein [KO:K04377]
125698200  FBXO22; F-box only protein 22 [KO:K10302]
125700066  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
125686210  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
125702608  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
125699220  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
125690379  BIRC2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
125690929  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
125685686  GAPDH; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
125697632  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1 [KO:K04721]
125685252  tumor necrosis factor receptor superfamily member 10A-like isoform X1 [KO:K04722]
125695241  FADD; FAS-associated death domain protein [KO:K02373]
125696903  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
125696904  caspase-8-like [KO:K04398] [EC:3.4.22.61]
125684299  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
125695713  cytochrome c [KO:K08738]
125690650  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
125692760  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
125694197  CASP7; caspase-7 [KO:K04397] [EC:3.4.22.60]
125688734  RHOB; rho-related GTP-binding protein RhoB [KO:K07856]
125692258  RHOH; rho-related GTP-binding protein RhoH [KO:K07873]
125689872  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125694568  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125699072  MLKL; mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
125698373  TXN2; thioredoxin, mitochondrial [KO:K03671]
125687373  thioredoxin [KO:K03671]
125703079  caspase-1-like [KO:K01370] [EC:3.4.22.36]
125703550  IL18; interleukin-18 [KO:K05482]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
lmut04010  MAPK signaling pathway
lmut04210  Apoptosis
lmut04217  Necroptosis
lmut04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
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