KEGG   PATHWAY: mun05132
Entry
mun05132                    Pathway                                
Name
Salmonella infection - Meriones unguiculatus (Mongolian gerbil)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
mun05132  Salmonella infection
mun05132

Disease
H00111  Typhoid fever
Organism
Meriones unguiculatus (Mongolian gerbil) [GN:mun]
Gene
110539463  Il6; interleukin-6 [KO:K05405]
110539680  [KO:K12757]
110539681  [KO:K12757]
110540136  Actr3; actin-related protein 3 [KO:K18584]
110540177  Rab7b; ras-related protein Rab-7b isoform X1 [KO:K07898]
110540284  [KO:K07375]
110540436  Tubb6; tubulin beta-6 chain [KO:K07375]
110540460  Actr2; actin-related protein 2 isoform X1 [KO:K17260]
110540621  Tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
110540697  [KO:K06071] [EC:2.7.11.13]
110540728  [KO:K04513]
110541022  Tab3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X2 [KO:K12793]
110541202  Tcf7l1; transcription factor 7-like 1 isoform X1 [KO:K04490]
110541283  Txn; thioredoxin [KO:K03671]
110541384  Pak3; serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
110541556  Rock2; rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.39]
110541773  Tlr2; toll-like receptor 2 [KO:K10159]
110541972  Kif5b; kinesin-1 heavy chain [KO:K10396] [EC:5.6.1.3]
110542950  [KO:K05759]
110543564  [KO:K05754]
110543676  Bak1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
110543688  [KO:K05757]
110544163  [KO:K05754]
110544653  [KO:K04467] [EC:2.7.11.10]
110544688  Tlr5; toll-like receptor 5 [KO:K10168]
110544926  Tubb2a; tubulin beta-2A chain [KO:K07375]
110545010  Cdc42; cell division control protein 42 homolog isoform X2 [KO:K04393]
110545018  Plekhm2; pleckstrin homology domain-containing family M member 2 isoform X2 [KO:K15348]
110545065  Ripk2; receptor-interacting serine/threonine-protein kinase 2 isoform X1 [KO:K08846] [EC:2.7.11.1]
110545113  Casp7; caspase-7 isoform X2 [KO:K04397] [EC:3.4.22.60]
110545126  Tcf7l2; transcription factor 7-like 2 isoform X10 [KO:K04491]
110545164  [KO:K08738]
110545240  Tubb3; tubulin beta-3 chain [KO:K07375]
110545330  Rala; ras-related protein Ral-A [KO:K07834]
110545339  Vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
110545344  Myl2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
110545345  Arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
110545449  Actr1b; beta-centractin [KO:K16575]
110545551  Tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
110545586  Dynll1; dynein light chain 1, cytoplasmic [KO:K10418]
110545639  [KO:K07937]
110545642  Plekhm1; pleckstrin homology domain-containing family M member 1 isoform X1 [KO:K23282]
110545654  Fhod1; FH1/FH2 domain-containing protein 1 [KO:K23938]
110545848  Pkn1; serine/threonine-protein kinase N1 isoform X2 [KO:K06071] [EC:2.7.11.13]
110546008  Mlkl; mixed lineage kinase domain-like protein isoform X1 [KO:K08849] [EC:2.7.11.1]
110546048  Tuba8; tubulin alpha-8 chain [KO:K07374]
110546082  Myl7; myosin regulatory light chain 2, atrial isoform isoform X2 [KO:K12754]
110546195  Arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
110546263  Tubb4a; tubulin beta-4A chain [KO:K07375]
110546507  Arpc5l; actin-related protein 2/3 complex subunit 5-like protein isoform X1 [KO:K05754]
110546562  Mapk14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
110546585  Mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
110546624  Snx33; sorting nexin-33 [KO:K17923]
110546680  Dctn4; dynactin subunit 4 isoform X1 [KO:K10426]
110546764  Rilp; rab-interacting lysosomal protein isoform X1 [KO:K13883]
110546864  Rras; ras-related protein R-Ras isoform X1 [KO:K07829]
110546885  Fadd; FAS-associated death domain protein [KO:K02373]
110546919  Pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
110546962  Fos; protein c-Fos [KO:K04379]
110547131  Dctn3; dynactin subunit 3 [KO:K10425]
110547224  Kpna1; importin subunit alpha-5 isoform X1 [KO:K23940]
110547315  Pak1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
110547396  [KO:K07374]
110547423  [KO:K07374]
110547871  Dynlt1; dynein light chain Tctex-type 1 [KO:K10420]
110547887  Snx9; sorting nexin-9 isoform X1 [KO:K17923]
110547901  Dync1li1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
110547978  Mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
110548007  Myl11; myosin regulatory light chain 11 [KO:K12758]
110548061  Exoc7; exocyst complex component 7 isoform X1 [KO:K07195]
110548259  Pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
110548333  Dctn6; dynactin subunit 6 isoform X1 [KO:K10428]
110548394  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
110548426  Arl8a; ADP-ribosylation factor-like protein 8A [KO:K07955]
110548451  Cyth4; cytohesin-4 isoform X1 [KO:K18441]
110548461  Txn2; thioredoxin, mitochondrial [KO:K03671]
110548539  Actr3b; actin-related protein 3B isoform X1 [KO:K18584]
110548566  Gapdh; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
110548597  [KO:K07374]
110548604  Tnfrsf1a; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
110548804  Actg1; actin, cytoplasmic 2 [KO:K05692]
110548925  Brk1; protein BRICK1 [KO:K05752]
110548950  Arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
110549089  Cse1l; exportin-2 [KO:K18423]
110549229  Elmo2; engulfment and cell motility protein 2 isoform X3 [KO:K18985]
110549277  Dync1i1; cytoplasmic dynein 1 intermediate chain 1 isoform X1 [KO:K10415]
110549347  Rela; transcription factor p65 isoform X1 [KO:K04735]
110549541  Wasl; actin nucleation-promoting factor WASL isoform X1 [KO:K23612]
110549573  Rab7a; ras-related protein Rab-7a [KO:K07897]
110549598  Dynlrb2; dynein light chain roadblock-type 2 [KO:K10419]
110549622  Tcf7; transcription factor 7 isoform X6 [KO:K02620]
110549633  Skp1; S-phase kinase-associated protein 1 isoform X2 [KO:K03094]
110549650  Snx18; sorting nexin-18 [KO:K17923]
110549673  Mapk12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
110549680  Mapk11; mitogen-activated protein kinase 11 isoform X1 [KO:K04441] [EC:2.7.11.24]
110549768  Pfn3; profilin-3 [KO:K05759]
110549832  Dync1i2; cytoplasmic dynein 1 intermediate chain 2 isoform X3 [KO:K10415]
110549868  [KO:K08738]
110550006  Nlrp3; NACHT, LRR and PYD domains-containing protein 3 isoform X2 [KO:K12800]
110550148  [KO:K12757]
110550187  [KO:K10161]
110550214  [KO:K00134] [EC:1.2.1.12]
110550271  Cyth1; cytohesin-1 isoform X1 [KO:K18441]
110550346  Klc4; kinesin light chain 4 [KO:K10407]
110550488  Cyth2; cytohesin-2 [KO:K18441]
110550574  Dynlrb1; dynein light chain roadblock-type 1 isoform X2 [KO:K10419]
110550613  Vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
110550651  Dctn5; dynactin subunit 5 [KO:K10427]
110550664  Tlr6; toll-like receptor 6 [KO:K10169]
110550814  Raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X2 [KO:K04366] [EC:2.7.11.1]
110550900  Rab5c; ras-related protein Rab-5C [KO:K07889]
110551400  Il1b; interleukin-1 beta [KO:K04519]
110551505  Klc3; kinesin light chain 3 isoform X1 [KO:K10407]
110551824  Actr10; actin-related protein 10 [KO:K16576]
110551977  Fbxo22; F-box only protein 22 isoform X1 [KO:K10302]
110552139  Arl8b; ADP-ribosylation factor-like protein 8B isoform X1 [KO:K07955]
110552151  Arf1; ADP-ribosylation factor 1 [KO:K07937]
110552225  Map2k4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
110552285  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
110552460  Dnm2; dynamin-2 isoform X5 [KO:K23484]
110552819  [KO:K08738]
110552936  Casp1; caspase-1 [KO:K01370] [EC:3.4.22.36]
110552966  Chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
110553183  Pfn4; profilin-4 [KO:K05759]
110553235  Hsp90aa1; heat shock protein HSP 90-alpha [KO:K04079]
110553239  Dync1h1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
110553271  Vps16; vacuolar protein sorting-associated protein 16 homolog isoform X1 [KO:K20180]
110553391  Lef1; lymphoid enhancer-binding factor 1 isoform X2 [KO:K04492]
110553751  Birc3; baculoviral IAP repeat-containing protein 3 isoform X1 [KO:K16060]
110553757  Birc2; baculoviral IAP repeat-containing protein 2 isoform X4 [KO:K16060]
110553796  Mapk1; mitogen-activated protein kinase 1 isoform X2 [KO:K04371] [EC:2.7.11.24]
110553931  Hras; GTPase HRas isoform X1 [KO:K02833]
110554045  Cyfip2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
110554129  Fyco1; FYVE and coiled-coil domain-containing protein 1 [KO:K21954]
110554227  Pfn2; profilin-2 isoform X1 [KO:K05759]
110554649  Pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
110554757  Vps39; vam6/Vps39-like protein isoform X1 [KO:K20183]
110555055  Nod1; nucleotide-binding oligomerization domain-containing protein 1 isoform X1 [KO:K08727]
110555059  Myd88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
110555283  Tirap; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
110555432  Pik3c2g; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
110555605  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
110555839  Hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
110555979  [KO:K08738]
110556252  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
110556292  M6pr; cation-dependent mannose-6-phosphate receptor [KO:K10089]
110556344  [KO:K00134] [EC:1.2.1.12]
110556479  Klc2; kinesin light chain 2 [KO:K10407]
110556511  Ripk3; receptor-interacting serine/threonine-protein kinase 3 isoform X1 [KO:K08847] [EC:2.7.11.1]
110556534  Actr1a; alpha-centractin isoform X1 [KO:K16575]
110556613  Ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
110556719  Akt2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
110556819  Tubb1; tubulin beta-1 chain isoform X1 [KO:K07375]
110556916  Arf6; ADP-ribosylation factor 6 [KO:K07941]
110556939  Myl9; myosin regulatory light polypeptide 9 [KO:K12755]
110557003  Traf2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
110557020  Tubb4b; tubulin beta-4B chain [KO:K07375]
110557077  [KO:K04722]
110557133  Tubb; tubulin beta chain [KO:K07375]
110557238  Myl10; myosin regulatory light chain 10 isoform X2 [KO:K12756]
110557299  Kpna4; importin subunit alpha-3 [KO:K23583]
110557321  Pfn1; profilin-1 [KO:K05759]
110557360  Cd14; monocyte differentiation antigen CD14 [KO:K04391]
110557386  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
110557410  Cyth3; cytohesin-3 [KO:K18441]
110557417  Rac1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
110557487  Tnfsf10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
110557497  Traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
110557546  Rhog; rho-related GTP-binding protein RhoG [KO:K07863]
110557571  Rhoj; rho-related GTP-binding protein RhoJ [KO:K07864]
110557597  Nckap1l; nck-associated protein 1-like [KO:K05750]
110557662  Casp8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
110557800  Bcl2; apoptosis regulator Bcl-2 [KO:K02161]
110557813  Tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
110557961  Cyfip1; cytoplasmic FMR1-interacting protein 1 isoform X2 [KO:K05749]
110557981  Anxa2; annexin A2 [KO:K17092]
110558069  Rhob; rho-related GTP-binding protein RhoB [KO:K07856]
110558076  Dync2li1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
110558093  Dync2h1; cytoplasmic dynein 2 heavy chain 1 isoform X1 [KO:K10414]
110558158  Exoc2; exocyst complex component 2 [KO:K17637]
110558188  Actb; actin, cytoplasmic 1 [KO:K05692]
110558395  Rhoh; rho-related GTP-binding protein RhoH [KO:K07873]
110558602  Nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X2 [KO:K02580]
110558877  Kif5c; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
110558966  Akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
110559000  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
110559249  Abi1; abl interactor 1 isoform X1 [KO:K23649]
110559338  Dctn1; dynactin subunit 1 isoform X1 [KO:K04648]
110559387  Rab5b; ras-related protein Rab-5B [KO:K07888]
110559487  Acbd3; Golgi resident protein GCP60 [KO:K23935]
110559601  [KO:K08738]
110559727  Jun; transcription factor Jun [KO:K04448]
110559740  Dync1li2; cytoplasmic dynein 1 light intermediate chain 2 [KO:K10416]
110559950  Rab9a; ras-related protein Rab-9A [KO:K07899]
110560064  Myc; myc proto-oncogene protein [KO:K04377]
110560136  Tnf; LOW QUALITY PROTEIN: tumor necrosis factor [KO:K03156]
110560152  Ptprc; receptor-type tyrosine-protein phosphatase C isoform X3 [KO:K06478] [EC:3.1.3.48]
110560172  Klc1; kinesin light chain 1 isoform X1 [KO:K10407]
110560408  Rps3; small ribosomal subunit protein uS3 [KO:K02985]
110560658  Bax; apoptosis regulator BAX isoform X1 [KO:K02159]
110560703  Tubal3; tubulin alpha chain-like 3 isoform X1 [KO:K07374]
110560705  Gcc2; GRIP and coiled-coil domain-containing protein 2 [KO:K20282]
110561167  Nckap1; nck-associated protein 1 isoform X1 [KO:K05750]
110561212  Podxl; podocalyxin [KO:K06817]
110561376  Ripk1; receptor-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K02861] [EC:2.7.11.1]
110561398  Kif5a; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
110561405  Dctn2; dynactin subunit 2 [KO:K10424]
110561533  Kpna3; importin subunit alpha-4 isoform X2 [KO:K23583]
110561634  Dynll2; dynein light chain 2, cytoplasmic [KO:K10418]
110561673  Vps41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
110561677  Map2k3; dual specificity mitogen-activated protein kinase kinase 3 isoform X2 [KO:K04432] [EC:2.7.12.2]
110561755  Ctnnb1; catenin beta-1 [KO:K02105]
110561834  Arhgef26; rho guanine nucleotide exchange factor 26 isoform X1 [KO:K13744]
110562014  Il18; interleukin-18 [KO:K05482]
110562349  Exoc5; exocyst complex component 5 [KO:K19984]
110562401  Nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
110562528  Ikbkg; NF-kappa-B essential modulator isoform X3 [KO:K07210]
110562530  Flna; filamin-A isoform X1 [KO:K04437]
110562575  Vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
110562802  Exoc4; exocyst complex component 4 isoform X1 [KO:K06111]
110562875  Mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
110562913  [KO:K10419]
110563015  Map2k6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
110563085  Gsdmd; gasdermin-D [KO:K20917]
110563105  Arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
110563106  Arpc1a; actin-related protein 2/3 complex subunit 1A isoform X1 [KO:K05757]
110563439  [KO:K08738]
110563555  S100a10; protein S100-A10 [KO:K17274]
110563636  Irak4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
110563924  Hsp90b1; endoplasmin [KO:K09487]
110564231  Rab9b; ras-related protein Rab-9B [KO:K07900]
110564542  Pycard; apoptosis-associated speck-like protein containing a CARD isoform X1 [KO:K12799]
110564799  Myo6; unconventional myosin-VI isoform X1 [KO:K10358]
110564898  Akt3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
110565014  Dynlt3; dynein light chain Tctex-type 3 [KO:K10420]
110565083  Pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1 [KO:K21289] [EC:2.7.1.153]
110565106  Nlrc4; NLR family CARD domain-containing protein 4 isoform X1 [KO:K12805]
110565112  Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
110565123  Rhoa; transforming protein RhoA isoform X2 [KO:K04513]
110565332  Tlr4; toll-like receptor 4 [KO:K10160]
110565695  Rab5a; ras-related protein Rab-5A isoform X1 [KO:K07887]
110565808  Map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
110566496  Arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
110566945  Irak1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
110566956  [KO:K07374]
132646048  [KO:K12807]
132650544  Map2k7; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 7 [KO:K04431] [EC:2.7.12.2]
132653623  Casp3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
132654295  [KO:K07374]
132654707  [KO:K12807]
132654713  [KO:K12807]
132654750  Ly96; lymphocyte antigen 96 [KO:K05400]
132655748  [KO:K07374]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
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  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
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Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
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PMID:22702524
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van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
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Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
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PMID:27222578
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Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
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Proc Natl Acad Sci U S A 113:6338-44 (2016)
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PMID:19157959
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McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
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Salmonella takes control: effector-driven manipulation of the host.
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Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
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PMID:12675800
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Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
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Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
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Mol Microbiol 48:401-15 (2003)
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Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
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J Cell Biol 175:453-63 (2006)
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Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
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Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
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Infect Immun 76:2722-35 (2008)
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A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
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Related
pathway
mun04010  MAPK signaling pathway
mun04064  NF-kappa B signaling pathway
mun04210  Apoptosis
mun04217  Necroptosis
mun04621  NOD-like receptor signaling pathway
KO pathway
ko05132   

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