KEGG   PATHWAY: nni05132
Entry
nni05132                    Pathway                                
Name
Salmonella infection - Nipponia nippon (crested ibis)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
nni05132  Salmonella infection
nni05132

Organism
Nipponia nippon (crested ibis) [GN:nni]
Gene
104010523  PODXL; podocalyxin [KO:K06817]
104020942  PTPRC; receptor-type tyrosine-protein phosphatase C [KO:K06478] [EC:3.1.3.48]
104013901  RAB5A; ras-related protein Rab-5A isoform X1 [KO:K07887]
104017466  RAB5B; ras-related protein Rab-5B isoform X1 [KO:K07888]
104009874  RAB5C; ras-related protein Rab-5C isoform X1 [KO:K07889]
104022657  RAB7A; ras-related protein Rab-7a isoform X1 [KO:K07897]
104013122  RAB7B; ras-related protein Rab-7b [KO:K07898]
104012275  PLEKHM1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
104016213  VPS11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
104011627  VPS16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
104020360  VPS18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
104020711  VPS33A; vacuolar protein sorting-associated protein 33A [KO:K20182]
104020439  VPS39; vam6/Vps39-like protein [KO:K20183]
104010304  VPS41; vacuolar protein sorting-associated protein 41 homolog isoform X1 [KO:K20184]
104016730  RILP; rab-interacting lysosomal protein [KO:K13883]
104014544  DYNC1H1; LOW QUALITY PROTEIN: cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
104023066  DYNC2H1; cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
104009997  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
104012811  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 isoform X1 [KO:K10415]
104013286  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 [KO:K10416]
104013954  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
104019691  DYNC2LI1; LOW QUALITY PROTEIN: cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
104011462  dynein light chain 1, cytoplasmic [KO:K10418]
104011500  dynein light chain 1, cytoplasmic-like [KO:K10418]
104016303  DYNLL2; dynein light chain 2, cytoplasmic [KO:K10418]
104019973  DYNLRB1; dynein light chain roadblock-type 1 [KO:K10419]
104014671  DYNLRB2; dynein light chain roadblock-type 2 [KO:K10419]
104020082  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
104008872  DYNLT1; dynein light chain Tctex-type 1 [KO:K10420]
104011629  DCTN1; dynactin subunit 1 [KO:K04648]
104019185  dynactin subunit 2-like [KO:K10424]
104013051  dynactin subunit 3-like [KO:K10425]
104017607  dynactin subunit 3-like [KO:K10425]
104014205  DCTN4; dynactin subunit 4 isoform X1 [KO:K10426]
104015280  DCTN5; dynactin subunit 5 [KO:K10427]
104016607  DCTN6; dynactin subunit 6 [KO:K10428]
104022300  ACTR1A; alpha-centractin [KO:K16575]
104020202  TUBA8; tubulin alpha-8 chain [KO:K07374]
104010483  TUBAL3; tubulin alpha chain-like 3 [KO:K07374]
104010484  tubulin alpha-3 chain-like [KO:K07374]
104015619  tubulin alpha-3 chain [KO:K07374]
104010053  tubulin alpha-1 chain isoform X1 [KO:K07374]
104010055  tubulin alpha-1B chain-like [KO:K07374]
104010056  LOW QUALITY PROTEIN: tubulin alpha-5 chain-like [KO:K07374]
104017935  tubulin alpha-2/alpha-4 chain-like [KO:K07374]
104011077  tubulin alpha-8 chain [KO:K07374]
104009564  TUBB1; tubulin beta-1 chain isoform X1 [KO:K07375]
104021837  tubulin beta-2 chain [KO:K07375]
104021839  tubulin beta-2 chain-like [KO:K07375]
104014478  tubulin beta-7 chain [KO:K07375]
104023623  TUBB3; tubulin beta-3 chain [KO:K07375]
104017658  TUBB6; tubulin beta-6 chain [KO:K07375]
104022259  TUBB4B; tubulin beta-4B chain [KO:K07375]
104012120  FYCO1; FYVE and coiled-coil domain-containing protein 1 [KO:K21954]
104011833  ADP-ribosylation factor-like protein 8B [KO:K07955]
104011072  ARL8A; ADP-ribosylation factor-like protein 8A [KO:K07955]
104016946  ARL8B; ADP-ribosylation factor-like protein 8B [KO:K07955]
104011191  PLEKHM2; pleckstrin homology domain-containing family M member 2 [KO:K15348]
104009792  KIF5C; kinesin heavy chain isoform 5C [KO:K10396]
104022280  KIF5B; kinesin-1 heavy chain [KO:K10396]
104020514  KIF5A; kinesin heavy chain isoform 5A [KO:K10396]
104018544  KLC4; kinesin light chain 4 [KO:K10407]
104014524  KLC1; kinesin light chain 1 isoform X1 [KO:K10407]
104019290  ACBD3; Golgi resident protein GCP60 [KO:K23935]
104008684  RHOA; transforming protein RhoA [KO:K04513]
104014579  M6PR; cation-dependent mannose-6-phosphate receptor [KO:K10089]
104022544  RAB9A; ras-related protein Rab-9A [KO:K07899]
104015356  RAB9B; ras-related protein Rab-9B [KO:K07900]
104019403  GCC2; GRIP and coiled-coil domain-containing protein 2 [KO:K20282]
104011541  profilin-1-like [KO:K05759]
104011576  profilin-2-like [KO:K05759]
104014653  PFN4; profilin-4 [KO:K05759]
104019559  LOW QUALITY PROTEIN: filamin-A-like [KO:K04437]
104022874  EXOC7; LOW QUALITY PROTEIN: exocyst complex component 7 [KO:K07195]
104019427  EXOC5; exocyst complex component 5 isoform X1 [KO:K19984]
104010486  EXOC4; exocyst complex component 4 [KO:K06111]
104021844  EXOC2; exocyst complex component 2 [KO:K17637]
104012419  RALA; ras-related protein Ral-A [KO:K07834]
104016716  actin, cytoplasmic type 5 isoform X1 [KO:K05692]
104014277  ACTG1; actin, cytoplasmic 2 isoform X1 [KO:K05692]
104015100  ACTB; actin, cytoplasmic 1 isoform X1 [KO:K05692]
104014418  S100A10; protein S100-A10 [KO:K17274]
104016832  ANXA2; annexin A2 [KO:K17092]
104015836  uncharacterized protein LOC104015836 [KO:K23934]
104018443  AHNAK; neuroblast differentiation-associated protein AHNAK [KO:K23934]
104010129  RHOJ; rho-related GTP-binding protein RhoJ [KO:K07864]
104011586  ARHGEF26; rho guanine nucleotide exchange factor 26 [KO:K13744]
104011778  RHOG; rho-related GTP-binding protein RhoG isoform X1 [KO:K07863]
104012905  rho-related GTP-binding protein RhoG-like [KO:K07863]
104012087  ELMO1; engulfment and cell motility protein 1 isoform X1 [KO:K12366]
104018299  ELMO2; engulfment and cell motility protein 2 [KO:K18985]
104013015  ROCK2; LOW QUALITY PROTEIN: rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.1]
104019401  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
104022604  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
104019952  MYL9; myosin regulatory light polypeptide 9 isoform X1 [KO:K12755]
104016106  MYL10; myosin regulatory light chain 10 [KO:K12756]
104017681  myosin regulatory light chain 2, smooth muscle minor isoform isoform X1 [KO:K12757]
104015764  myosin regulatory light chain 2, smooth muscle minor isoform isoform X1 [KO:K12757]
104017440  FHOD1; FH1/FH2 domain-containing protein 1 [KO:K23938]
104011199  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
104015059  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
104015301  NCKAP1; nck-associated protein 1 [KO:K05750]
104011960  NCKAP1L; LOW QUALITY PROTEIN: nck-associated protein 1-like [KO:K05750]
104019312  CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749]
104014228  CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
104016203  ABI1; abl interactor 1 isoform X1 [KO:K23649]
104023027  WASF3; wiskott-Aldrich syndrome protein family member 3 isoform X1 [KO:K06083]
104023505  wiskott-Aldrich syndrome protein family member 3-like [KO:K06083]
104018940  ACTR2; actin-related protein 2 [KO:K17260]
104009782  ACTR3; actin-related protein 3 [KO:K18584]
104014903  ACTR3B; actin-related protein 3B [KO:K18584]
104015104  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
104015105  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
104010112  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
104019550  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
104023327  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
104011316  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
104022736  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
104023254  PAK3; serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
104022030  MYO6; LOW QUALITY PROTEIN: unconventional myosin-VI [KO:K10358]
104008980  PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
104023668  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
104019595  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
104010725  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
104013205  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
104017951  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
104010656  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
104015197  CYTH3; cytohesin-3 [KO:K18441]
104021591  CYTH4; cytohesin-4 [KO:K18441]
104018616  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
104019454  ARF6; ADP-ribosylation factor 6 [KO:K07941]
104021730  ARF1; ADP-ribosylation factor 1 [KO:K07937]
104008792  SNX9; sorting nexin-9 isoform X1 [KO:K17923]
104011930  sorting nexin-18-like [KO:K17923]
104016727  SNX33; sorting nexin-33 [KO:K17923]
104011819  WASL; neural Wiskott-Aldrich syndrome protein [KO:K23612]
104012397  DNM2; dynamin-2 [KO:K23484] [EC:3.6.5.5]
104009810  toll-like receptor 1 [KO:K10169]
104021229  TLR2; toll-like receptor 2 [KO:K10159]
104021230  toll-like receptor 2 type-2 [KO:K10159]
104008501  toll-like receptor 2 type-2 [KO:K10159]
104016675  TIRAP; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
104021773  MYD88; LOW QUALITY PROTEIN: myeloid differentiation primary response protein MyD88 [KO:K04729]
104022144  CD14; monocyte differentiation antigen CD14 [KO:K04391]
104022122  TLR4; toll-like receptor 4 [KO:K10160]
104016168  LY96; lymphocyte antigen 96 [KO:K05400]
104019645  TLR5; toll-like receptor 5 [KO:K10168]
104013612  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
104019573  TNF receptor-associated factor 6-like [KO:K03175] [EC:2.3.2.27]
104021941  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
104021621  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
104013777  TAB2; LOW QUALITY PROTEIN: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
104020077  TAB3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 [KO:K12793]
104016028  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
104011799  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
104021184  NFKB1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
104018480  NOD1; LOW QUALITY PROTEIN: nucleotide-binding oligomerization domain-containing protein 1 [KO:K08727]
104014508  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
104021515  HSP90AB1; heat shock protein HSP 90-beta isoform X1 [KO:K04079]
104013355  HSP90B1; endoplasmin [KO:K09487]
104016365  receptor-interacting serine/threonine-protein kinase 2-like [KO:K08846] [EC:2.7.11.1]
104016403  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [KO:K08846] [EC:2.7.11.1]
104013074  CSE1L; exportin-2 isoform X1 [KO:K18423]
104008609  KPNA1; importin subunit alpha-5 [KO:K23940]
104011568  KPNA4; importin subunit alpha-3 [KO:K23583]
104010892  KPNA3; importin subunit alpha-4 [KO:K23583]
104022720  RPS3; 40S ribosomal protein S3 isoform X1 [KO:K02985]
104017304  HRAS; GTPase HRas [KO:K02833]
104022929  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
104017047  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
104018809  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
104020099  MAPK1; LOW QUALITY PROTEIN: mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
104015109  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 [KO:K04432] [EC:2.7.12.2]
104014353  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
104010702  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
104010773  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
104010338  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
104013235  MAPK14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
104014564  MAP2K4; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 4 [KO:K04430] [EC:2.7.12.2]
104018444  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
104013238  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
104019815  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
104009262  JUN; transcription factor AP-1 isoform X1 [KO:K04448]
104022599  interleukin-1 receptor antagonist protein-like [KO:K04519]
104013985  IL6; interleukin-6 [KO:K05405]
104015862  interleukin-8-like [KO:K10030]
104015863  interleukin-8 [KO:K10030]
104015873  interleukin-8-like [KO:K10030]
104012111  CTNNB1; catenin beta-1 [KO:K02105]
104012004  TCF7; transcription factor 7 [KO:K02620]
104022615  TCF7L1; transcription factor 7-like 1 [KO:K04490]
104022375  TCF7L2; transcription factor 7-like 2 [KO:K04491]
104021166  LEF1; LOW QUALITY PROTEIN: lymphoid enhancer-binding factor 1 [KO:K04492]
104016870  MYC; myc proto-oncogene protein [KO:K04377]
104016821  FBXO22; F-box only protein 22 [KO:K10302]
104012003  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
104008622  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
104018369  TRAF2; LOW QUALITY PROTEIN: TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
104016373  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
104023072  BIRC2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
104021840  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
104009682  GAPDH; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
104022070  TNFSF10; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 10 [KO:K04721]
104019542  TNFRSF10B; tumor necrosis factor receptor superfamily member 10B [KO:K04722]
104009489  FADD; FAS-associated death domain protein [KO:K02373]
104010196  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
104013218  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
104013931  cytochrome c [KO:K08738]
104010288  LOW QUALITY PROTEIN: cytochrome c, somatic-like [KO:K08738]
104021857  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
104021286  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
104022338  CASP7; caspase-7 [KO:K04397] [EC:3.4.22.60]
104022617  caspase-3-like [KO:K04397] [EC:3.4.22.60]
104014640  rho-related GTP-binding protein RhoB [KO:K07856]
104009799  RHOH; rho-related GTP-binding protein RhoH [KO:K07873]
104020263  AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
104014534  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
104011272  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
104017499  MLKL; mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
104019850  thioredoxin-like [KO:K03671]
104021573  TXN2; thioredoxin, mitochondrial [KO:K03671]
104011420  NACHT, LRR and PYD domains-containing protein 3-like [KO:K12800]
104019902  NAIP; baculoviral IAP repeat-containing protein 1 [KO:K12807]
104018706  NLRC4; NLR family CARD domain-containing protein 4 [KO:K12805]
104012458  caspase-1-like [KO:K01370] [EC:3.4.22.36]
104019045  IL18; interleukin-18 [KO:K05482]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
nni04010  MAPK signaling pathway
nni04210  Apoptosis
nni04217  Necroptosis
nni04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
LinkDB

DBGET integrated database retrieval system