KEGG   PATHWAY: pmei05132
Entry
pmei05132                   Pathway                                
Name
Salmonella infection - Poecilia mexicana (shortfin molly)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
pmei05132  Salmonella infection
pmei05132

Organism
Poecilia mexicana (shortfin molly) [GN:pmei]
Gene
106925086  podxl; podocalyxin [KO:K06817]
106929327  ptprc; receptor-type tyrosine-protein phosphatase C [KO:K06478] [EC:3.1.3.48]
106927543  ras-related protein Rab-5A [KO:K07887]
106929564  ras-related protein Rab-5A-like [KO:K07887]
106906665  ras-related protein Rab-5B-like [KO:K07888]
106932477  ras-related protein Rab-5B-like [KO:K07888]
106926197  ras-related protein Rab-5C-like [KO:K07889]
106921571  rab5c; ras-related protein Rab-5C [KO:K07889]
106932178  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
106905591  ras-related protein Rab-7a-like [KO:K07897]
106933604  rab7a; ras-related protein Rab-7a [KO:K07897]
106929788  ras-related protein Rab-7a [KO:K07897]
106921396  plekhm1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
106911200  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
106928012  vps16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
106923215  vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
106921234  vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
106919000  vps39; vam6/Vps39-like protein [KO:K20183]
106916075  vps41; vacuolar protein sorting-associated protein 41 homolog isoform X1 [KO:K20184]
106924303  rilp; rab-interacting lysosomal protein [KO:K13883]
106905089  dync1h1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
106918004  dync2h1; cytoplasmic dynein 2 heavy chain 1 isoform X1 [KO:K10414]
106932927  cytoplasmic dynein 1 intermediate chain 2-like isoform X1 [KO:K10415]
106934095  cytoplasmic dynein 1 intermediate chain 2-like isoform X1 [KO:K10415]
106923091  cytoplasmic dynein 1 intermediate chain 1-like [KO:K10415]
106921027  cytoplasmic dynein 1 light intermediate chain 1-like [KO:K10416]
106928140  dync1li2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
106909576  dync2li1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
106908954  dynll2; dynein light chain 2, cytoplasmic [KO:K10418]
106921194  dynein light chain 2, cytoplasmic-like [KO:K10418]
106921752  dynein light chain 2, cytoplasmic-like [KO:K10418]
106909198  dynein light chain roadblock-type 1-like [KO:K10419]
106909204  dynein light chain roadblock-type 1 [KO:K10419]
106926599  dynlrb2; dynein light chain roadblock-type 2 [KO:K10419]
106919584  dynein light chain Tctex-type 1-like isoform X1 [KO:K10420]
106920041  dynlt1; dynein light chain Tctex-type 1 [KO:K10420]
106930161  dynlt3; dynein light chain Tctex-type 3 [KO:K10420]
106919208  dctn1; dynactin subunit 1 isoform X1 [KO:K04648]
106933062  dynactin subunit 1-like isoform X1 [KO:K04648]
106928411  dctn2; dynactin subunit 2 isoform X1 [KO:K10424]
106909211  dctn3; dynactin subunit 3 [KO:K10425]
106933373  dctn4; dynactin subunit 4 isoform X1 [KO:K10426]
106915213  dctn5; dynactin subunit 5 [KO:K10427]
106916251  dctn6; dynactin subunit 6 [KO:K10428]
106923586  dynactin subunit 6-like [KO:K10428]
106922498  beta-centractin [KO:K16575]
106922135  actr10; actin-related protein 10 [KO:K16576]
106919590  tuba4a; tubulin alpha-4A chain [KO:K07374]
106913013  tubulin alpha-4 chain [KO:K07374]
106913033  tubulin alpha-4 chain [KO:K07374]
106913179  tubulin alpha-4 chain [KO:K07374]
106907920  tubulin alpha chain-like isoform X1 [KO:K07374]
106916769  tubulin alpha-8 chain-like [KO:K07374]
106916813  tubulin alpha-1C chain-like [KO:K07374]
106910559  tubulin alpha chain isoform X1 [KO:K07374]
106920551  tubulin alpha chain-like [KO:K07374]
106920718  tubulin alpha-1B chain-like isoform X1 [KO:K07374]
106920719  tubulin alpha-1A chain [KO:K07374]
106921823  tubulin alpha-1B chain [KO:K07374]
106922100  tubulin alpha-1C chain-like isoform X1 [KO:K07374]
106922742  tubulin alpha-1B chain-like [KO:K07374]
106924581  tubulin alpha-1B chain-like [KO:K07374]
106920392  tubulin beta-1 chain-like [KO:K07375]
106914304  tubulin beta chain-like [KO:K07375]
106906032  tubulin beta chain-like [KO:K07375]
106906232  tubulin beta-4B chain-like [KO:K07375]
106917856  tubulin beta chain [KO:K07375]
106903421  tubulin beta-6 chain [KO:K07375]
106918920  tubulin beta chain-like isoform X1 [KO:K07375]
106919024  tubulin beta-4B chain-like [KO:K07375]
106933602  tubulin beta-4B chain-like [KO:K07375]
106928478  tubulin beta-4B chain-like [KO:K07375]
106929551  tubulin beta-1 chain [KO:K07375]
106924173  tubulin beta chain-like [KO:K07375]
106914364  tubulin beta-1 chain-like [KO:K07375]
106904412  FYVE and coiled-coil domain-containing protein 1-like [KO:K21954]
106916802  FYVE and coiled-coil domain-containing protein 1-like [KO:K21954]
106916327  ADP-ribosylation factor-like protein 8B-A [KO:K07955]
106909381  ADP-ribosylation factor-like protein 8A [KO:K07955]
106929003  ADP-ribosylation factor-like protein 8B [KO:K07955]
106926257  plekhm2; pleckstrin homology domain-containing family M member 2 isoform X1 [KO:K15348]
106905706  kif5c; kinesin heavy chain isoform 5C [KO:K10396]
106915189  kinesin-1 heavy chain-like isoform X1 [KO:K10396]
106906931  kinesin-1 heavy chain [KO:K10396]
106915585  kinesin heavy chain isoform 5A-like [KO:K10396]
106908438  kinesin heavy chain isoform 5C-like [KO:K10396]
106928430  kif5a; kinesin heavy chain isoform 5A isoform X1 [KO:K10396]
106920396  klc1; kinesin light chain 1 isoform X1 [KO:K10407]
106908398  kinesin light chain 1-like [KO:K10407]
106917600  klc2; kinesin light chain 2 isoform X1 [KO:K10407]
106933311  kinesin light chain 1-like isoform X1 [KO:K10407]
106904751  acbd3; Golgi resident protein GCP60 isoform X1 [KO:K23935]
106905410  rho-related GTP-binding protein RhoA-B-like [KO:K04513]
106918068  transforming protein RhoA [KO:K04513]
106903887  rho-related GTP-binding protein RhoA-B-like [KO:K04513]
106926573  rho-related GTP-binding protein RhoA-C isoform X1 [KO:K04513]
106925151  rho-related GTP-binding protein RhoA-D isoform X1 [KO:K04513]
106931696  rho-related GTP-binding protein RhoA-A-like [KO:K04513]
106931768  rho-related GTP-binding protein RhoC-like [KO:K04513]
106916574  m6pr; cation-dependent mannose-6-phosphate receptor [KO:K10089]
106919858  rab9a; ras-related protein Rab-9A [KO:K07899]
106924960  ras-related protein Rab-9A-like [KO:K07899]
106919470  ras-related protein Rab-9B-like [KO:K07900]
106928386  ras-related protein Rab-9B-like [KO:K07900]
106903721  gcc2; GRIP and coiled-coil domain-containing protein 2 [KO:K20282]
106922847  stx10; syntaxin-10 [KO:K23937]
106904645  pfn1; profilin-1 [KO:K05759]
106918804  profilin-2-like isoform X1 [KO:K05759]
106932549  profilin-2-like isoform X1 [KO:K05759]
106924489  filamin-A-like isoform X1 [KO:K04437]
106931276  exoc7; exocyst complex component 7 isoform X1 [KO:K07195]
106917818  exoc5; exocyst complex component 5 [KO:K19984]
106916582  exoc4; exocyst complex component 4 [KO:K06111]
106914423  exoc2; exocyst complex component 2 [KO:K17637]
106912886  ras-related protein Ral-A [KO:K07834]
106908123  actin, cytoplasmic 2 [KO:K05692]
106927995  actb; actin, cytoplasmic 1 [KO:K05692]
106918185  protein S100-A1-like [KO:K17274]
106922621  protein S100-A1-like [KO:K17274]
106919763  anxa2; annexin A2 [KO:K17092]
106911065  annexin A2-like [KO:K17092]
106923069  annexin A2-like [KO:K17092]
106927077  rho guanine nucleotide exchange factor 26-like [KO:K13744]
106922302  rho-related GTP-binding protein RhoG-like [KO:K07863]
106928379  rho-related GTP-binding protein RhoG-like [KO:K07863]
106928391  rho-related GTP-binding protein RhoG-like [KO:K07863]
106933927  engulfment and cell motility protein 1 isoform X1 [KO:K12366]
106906831  elmo2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
106909746  rho-associated protein kinase 2-like [KO:K17388] [EC:2.7.11.1]
106910538  rho-associated protein kinase 2-like [KO:K17388] [EC:2.7.11.1]
106911054  rho-associated protein kinase 2-like [KO:K17388] [EC:2.7.11.1]
106920666  rho-associated protein kinase 2-like isoform X1 [KO:K17388] [EC:2.7.11.1]
106931922  myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
106927814  myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
106931433  myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
106929046  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
106914399  myosin regulatory light polypeptide 9 [KO:K12755]
106916086  myosin regulatory light chain 2, smooth muscle minor isoform-like [KO:K12757]
106923676  myosin regulatory light polypeptide 9 [KO:K12757]
106925968  myosin regulatory light chain 2, skeletal muscle isoform-like [KO:K12758]
106929603  mylpf; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
106904684  FH1/FH2 domain-containing protein 1-like isoform X1 [KO:K23938]
106919891  cell division control protein 42 homolog [KO:K04393]
106905228  cell division control protein 42 homolog [KO:K04393]
106933042  cell division control protein 42 homolog [KO:K04393]
106927935  cell division control protein 42 homolog isoform X1 [KO:K04393]
106922247  cell division control protein 42 homolog isoform X1 [KO:K04393]
106925835  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
106925836  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
106925837  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
106925839  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
106928254  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
106908725  nckap1l; nck-associated protein 1-like [KO:K05750]
106926844  nckap1; nck-associated protein 1 isoform X1 [KO:K05750]
106928619  nck-associated protein 1-like [KO:K05750]
106928067  cyfip1; cytoplasmic FMR1-interacting protein 1 [KO:K05749]
106928216  cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
106928308  abl interactor 1-like isoform X1 [KO:K23649]
106923948  abi1; abl interactor 1 isoform X1 [KO:K23649]
106923739  brk1; protein BRICK1 [KO:K05752]
106908948  wasf3; wiskott-Aldrich syndrome protein family member 3 isoform X1 [KO:K06083]
106927913  wiskott-Aldrich syndrome protein family member 3-like isoform X1 [KO:K06083]
106921955  wiskott-Aldrich syndrome protein family member 3-like [KO:K06083]
106913536  actr2; actin-related protein 2 isoform X1 [KO:K17260]
106917606  actin-related protein 2-like isoform X1 [KO:K17260]
106914882  actin-related protein 3 [KO:K18584]
106910959  actin-related protein 3 [KO:K18584]
106934166  actr3b; actin-related protein 3B isoform X1 [KO:K18584]
106905504  actin-related protein 2/3 complex subunit 1A [KO:K05757]
106905506  actin-related protein 2/3 complex subunit 1B-like [KO:K05757]
106910999  actin-related protein 2/3 complex subunit 1A-like [KO:K05757]
106924950  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
106918308  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
106923226  actin-related protein 2/3 complex subunit 4 [KO:K05755]
106929784  actin-related protein 2/3 complex subunit 4-like [KO:K05755]
106913885  arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
106907904  actin-related protein 2/3 complex subunit 5-like [KO:K05754]
106916502  pak1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
106923492  serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
106906138  unconventional myosin-VI-like [KO:K10358]
106926411  unconventional myosin-VI-like [KO:K10358]
106906548  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
106917126  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
106920607  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
106928990  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
106930552  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
106905118  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like isoform X1 [KO:K21289] [EC:2.7.1.153]
106910053  pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
106934247  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like [KO:K21289] [EC:2.7.1.153]
106908472  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
106926826  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
106931303  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
106920077  cytohesin-1 isoform X1 [KO:K18441]
106909539  cytohesin-2 isoform X1 [KO:K18441]
106909698  cytohesin-3-like [KO:K18441]
106925840  cytohesin-3 [KO:K18441]
106927466  cyth1; cytohesin-1 isoform X1 [KO:K18441]
106934044  cytohesin-2-like isoform X1 [KO:K18441]
106928257  cytohesin-3-like [KO:K18441]
106923891  cytohesin-3-like [KO:K18441]
106917833  arf6; ADP-ribosylation factor 6 [KO:K07941]
106920654  ADP-ribosylation factor 6 [KO:K07941]
106905864  ADP-ribosylation factor 1-like [KO:K07937]
106917290  ADP-ribosylation factor 1 [KO:K07937]
106925137  ADP-ribosylation factor 1-like [KO:K07937]
106914046  sorting nexin-18-like [KO:K17923]
106905830  snx33; sorting nexin-33 [KO:K17923]
106933269  snx18; sorting nexin-18 [KO:K17923]
106928018  sorting nexin-9-like [KO:K17923]
106928315  sorting nexin-9-like isoform X1 [KO:K17923]
106919367  wasl; neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612]
106908381  LOW QUALITY PROTEIN: neural Wiskott-Aldrich syndrome protein-like [KO:K23612]
106929780  wiskott-Aldrich syndrome protein-like [KO:K23612]
106932481  dnm2; dynamin-2 isoform X1 [KO:K23484] [EC:3.6.5.5]
106922044  dynamin-2-like isoform X1 [KO:K23484] [EC:3.6.5.5]
106920377  toll-like receptor 2 type-2 isoform X1 [KO:K10159]
106924268  tlr2; toll-like receptor 2 isoform X1 [KO:K10159]
106934185  tirap; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
106921037  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
106907834  tlr5; toll-like receptor 5 isoform X1 [KO:K10168]
106909765  irak1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
106909806  interleukin-1 receptor-associated kinase 4-like [KO:K04733] [EC:2.7.11.1]
106933748  irak4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
106907132  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
106921645  mitogen-activated protein kinase kinase kinase 7-like isoform X1 [KO:K04427] [EC:2.7.11.25]
106923896  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
106904317  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
106926274  tab3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
106907785  ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
106915153  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
106915993  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
106921755  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
106904394  NF-kappa-B inhibitor alpha-like [KO:K04734]
106922947  nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
106922882  nfkb1; LOW QUALITY PROTEIN: nuclear factor NF-kappa-B p105 subunit [KO:K02580]
106907458  transcription factor p65-like [KO:K04735]
106917390  nod1; nucleotide-binding oligomerization domain-containing protein 1 isoform X1 [KO:K08727]
106916348  heat shock protein HSP 90-alpha [KO:K04079]
106916349  heat shock protein HSP 90-alpha 1 [KO:K04079]
106932531  hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
106916490  hsp90b1; endoplasmin [KO:K09487]
106920595  ripk2; receptor-interacting serine/threonine-protein kinase 2 isoform X1 [KO:K08846] [EC:2.7.11.1]
106931053  cse1l; exportin-2 isoform X1 [KO:K18423]
106905246  kpna1; importin subunit alpha-5 [KO:K23940]
106917749  kpna4; importin subunit alpha-3 [KO:K23583]
106918459  kpna3; importin subunit alpha-4 isoform X1 [KO:K23583]
106917263  rps3; 40S ribosomal protein S3 [KO:K02985]
106917342  hras; GTPase HRas [KO:K02833]
106904980  raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
106924888  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
106915816  map2k2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
106919524  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
106906981  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
106920063  dual specificity mitogen-activated protein kinase kinase 6-like [KO:K04433] [EC:2.7.12.2]
106922419  dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
106931279  dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
106915443  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
106907848  mitogen-activated protein kinase 13-like [KO:K04441] [EC:2.7.11.24]
106917396  mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
106903247  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
106922726  mitogen-activated protein kinase 12-like isoform X1 [KO:K04441] [EC:2.7.11.24]
106922728  mitogen-activated protein kinase 11-like [KO:K04441] [EC:2.7.11.24]
106931374  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
106927114  dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
106924851  dual specificity mitogen-activated protein kinase kinase 4-like isoform X1 [KO:K04430] [EC:2.7.12.2]
106917328  map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
106915127  mitogen-activated protein kinase 8-like isoform X1 [KO:K04440] [EC:2.7.11.24]
106917997  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
106920878  mitogen-activated protein kinase 9-like isoform X1 [KO:K04440] [EC:2.7.11.24]
106924329  mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
106920010  proto-oncogene c-Fos-like isoform X1 [KO:K04379]
106920011  proto-oncogene c-Fos-like [KO:K04379]
106923538  proto-oncogene c-Fos-like isoform X1 [KO:K04379]
106919032  transcription factor AP-1-like [KO:K04448]
106920852  jun; transcription factor AP-1 [KO:K04448]
106924591  transcription factor jun-D-like [KO:K04448]
106908735  tumor necrosis factor-like [KO:K03156]
106907688  interleukin-1 beta-like [KO:K04519]
106904819  interleukin-8-like [KO:K10030]
106917623  permeability factor 2-like [KO:K10030]
106919066  ctnnb1; catenin beta-1 [KO:K02105]
106921026  catenin beta-1-like [KO:K02105]
106916700  tcf7; transcription factor 7 isoform X1 [KO:K02620]
106910477  transcription factor 7-like 1-A [KO:K02620]
106915824  transcription factor 7-like 1-A isoform X1 [KO:K04490]
106931867  transcription factor 7-like 1-A [KO:K04490]
106920911  tcf7l2; transcription factor 7-like 2 isoform X1 [KO:K04491]
106930845  lef1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
106905808  transcriptional regulator Myc-like [KO:K04377]
106916071  transcriptional regulator Myc-like [KO:K04377]
106921410  transcriptional regulator Myc-B-like [KO:K04377]
106930758  transcriptional regulator Myc-like [KO:K04377]
106917325  pkn1; serine/threonine-protein kinase N1 isoform X1 [KO:K06071] [EC:2.7.11.13]
106930631  serine/threonine-protein kinase N1-like isoform X1 [KO:K06071] [EC:2.7.11.13]
106920797  fbxo22; F-box only protein 22 [KO:K10302]
106916702  skp1; S-phase kinase-associated protein 1 [KO:K03094]
106921375  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
106921698  tumor necrosis factor receptor superfamily member 10B-like [KO:K03158]
106917048  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
106917430  traf2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
106930528  TNF receptor-associated factor 2-like isoform X1 [KO:K03173] [EC:2.3.2.27]
106913976  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
106921217  birc2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
106925927  ripk1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
106919852  glyceraldehyde-3-phosphate dehydrogenase-like [KO:K00134] [EC:1.2.1.12]
106921370  gapdh; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
106912519  tnfsf10; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 10 [KO:K04721]
106933885  tumor necrosis factor ligand superfamily member 10-like isoform X1 [KO:K04721]
106926654  tumor necrosis factor receptor superfamily member 10B-like isoform X1 [KO:K04722]
106934330  tumor necrosis factor receptor superfamily member 10B-like isoform X1 [KO:K04722]
106912590  fadd; FAS-associated death domain protein isoform X1 [KO:K02373]
106926427  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
106934087  uncharacterized protein LOC106934087 [KO:K04398] [EC:3.4.22.61]
106924075  caspase-8-like [KO:K04398] [EC:3.4.22.61]
106924079  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
106906322  receptor-interacting serine/threonine-protein kinase 3-like isoform X1 [KO:K08847] [EC:2.7.11.1]
106925217  receptor-interacting serine/threonine-protein kinase 4-like isoform X1 [KO:K08847] [EC:2.7.11.1]
106910517  apoptosis regulator BAX-like [KO:K02159]
106925142  apoptosis regulator BAX-like [KO:K02159]
106925143  apoptosis regulator BAX-like [KO:K02159]
106907627  cytochrome c [KO:K08738]
106910161  cytochrome c-b [KO:K08738]
106923569  cytochrome c iso-1/iso-2-like [KO:K08738]
106923581  cytochrome c, testis-specific-like [KO:K08738]
106919799  bcl2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
106906082  caspase-3-like [KO:K02187] [EC:3.4.22.56]
106931037  caspase-3-like [KO:K02187] [EC:3.4.22.56]
106907578  casp7; caspase-7 isoform X1 [KO:K04397] [EC:3.4.22.60]
106931868  caspase-3-like [KO:K04397] [EC:3.4.22.60]
106924038  rhob; rho-related GTP-binding protein RhoB [KO:K07856]
106914218  rhoh; rho-related GTP-binding protein RhoH [KO:K07873]
106913936  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
106932106  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
106933633  RAC-gamma serine/threonine-protein kinase-like isoform X1 [KO:K04456] [EC:2.7.11.1]
106927524  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
106908407  mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
106932506  mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
106918826  thioredoxin-like [KO:K03671]
106918827  thioredoxin-like [KO:K03671]
106930824  txn2; thioredoxin, mitochondrial [KO:K03671]
106920434  LOW QUALITY PROTEIN: apoptosis-associated speck-like protein containing a CARD [KO:K12799]
106920436  pycard; apoptosis-associated speck-like protein containing a CARD [KO:K12799]
106920431  caspase-4-like isoform X1 [KO:K01370] [EC:3.4.22.36]
106908161  uncharacterized protein LOC106908161 [KO:K01370] [EC:3.4.22.36]
106917731  caspase-1-like [KO:K01370] [EC:3.4.22.36]
106917742  caspase-1-like [KO:K01370] [EC:3.4.22.36]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
pmei04010  MAPK signaling pathway
pmei04210  Apoptosis
pmei04217  Necroptosis
pmei04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
LinkDB

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