KEGG   PATHWAY: umr04060
Entry
umr04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Ursus maritimus (polar bear)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
umr04060  Cytokine-cytokine receptor interaction
umr04060

Organism
Ursus maritimus (polar bear) [GN:umr]
Gene
103667274  CCL1; C-C motif chemokine 1 [KO:K05514]
103681730  CCL25; C-C motif chemokine 25 [KO:K13072]
103667060  CCL19; C-C motif chemokine 19 [KO:K05512]
103667061  CCL21; C-C motif chemokine 21 [KO:K16062]
103667298  C-C motif chemokine 3-like [KO:K05408]
103667297  C-C motif chemokine 3 [KO:K05408]
103667299  regakine-1-like [KO:K05408]
103667295  C-C motif chemokine 4 isoform X2 [KO:K12964]
103673761  CCL17; C-C motif chemokine 17 [KO:K21083]
103673763  CCL22; C-C motif chemokine 22 isoform X1 [KO:K21095]
103667294  CCL5; C-C motif chemokine 5 [KO:K12499]
103667272  CCL8; C-C motif chemokine 8 [KO:K16596]
103667301  C-C motif chemokine 14 [KO:K21092]
103667302  CCL16; C-C motif chemokine 16 [KO:K21093]
103667300  C-C motif chemokine 15 isoform X2 [KO:K05511]
103667273  C-C motif chemokine 13 [KO:K16595]
103667271  C-C motif chemokine 7 [KO:K05509]
103667270  C-C motif chemokine 2 [KO:K14624]
103670147  CCL24; C-C motif chemokine 24 [KO:K21097]
103670148  CCL26; C-C motif chemokine 26 [KO:K21096]
103667058  CCL27; C-C motif chemokine 27 [KO:K16598]
103667057  uncharacterized protein LOC103667057 isoform X1 [KO:K16598]
103664844  CCL28; C-C motif chemokine 28 [KO:K05513]
103662703  CCL20; C-C motif chemokine 20 [KO:K14625]
103665390  growth-regulated protein homolog beta-like [KO:K05505]
103665312  growth-regulated alpha protein-like [KO:K05505]
103665307  CXCL8; interleukin-8 [KO:K10030]
103665310  CXCL6; C-X-C motif chemokine 6 isoform X1 [KO:K10029]
103665311  PF4V1; platelet factor 4 variant [KO:K05407]
103665327  CXCL9; C-X-C motif chemokine 9 isoform X1 [KO:K05416]
103665330  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
103665329  CXCL11; C-X-C motif chemokine 11 [KO:K12672]
103665338  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
103667923  CXCL12; stromal cell-derived factor 1 [KO:K10031]
103660450  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
103663956  CXCL14; C-X-C motif chemokine 14 [KO:K10033]
103680156  CXCL17; C-X-C motif chemokine 17 [KO:K22627]
103667626  cytokine SCM-1 beta-like [KO:K22675]
103673762  CX3CL1; fractalkine [KO:K05508]
103661804  IL2; interleukin-2 [KO:K05429]
103663832  IL4; interleukin-4 [KO:K05430]
103661362  IL7; interleukin-7 [KO:K05431]
103663953  IL9; interleukin-9 [KO:K05432]
103657977  IL15; interleukin-15 isoform X1 [KO:K05433]
103661805  IL21; interleukin-21 [KO:K05434]
103675809  thymic stromal lymphopoietin [KO:K05436]
103670504  interleukin-3 [KO:K04736]
103663836  IL5; interleukin-5 [KO:K05428]
103670505  CSF2; granulocyte-macrophage colony-stimulating factor isoform X1 [KO:K05427]
103663833  IL13; LOW QUALITY PROTEIN: interleukin-13 [KO:K05435]
103670120  EPO; LOW QUALITY PROTEIN: erythropoietin [KO:K05437]
103665901  somatotropin [KO:K05438]
103678373  PRL; prolactin [KO:K05439]
103676077  THPO; thrombopoietin isoform X1 [KO:K06854]
103661676  CSF3; granulocyte colony-stimulating factor [KO:K05423]
103676631  leptin isoform X1 [KO:K05424]
103658871  IL6; interleukin-6 [KO:K05405]
103680260  IL11; interleukin-11 [KO:K05417]
103681335  IL12A; interleukin-12 subunit alpha [KO:K05406]
103664531  IL12B; interleukin-12 subunit beta isoform X1 [KO:K05425]
103656219  IL23A; interleukin-23 subunit alpha [KO:K05426]
103657820  IL27; interleukin-27 subunit alpha [KO:K22629]
103681680  EBI3; interleukin-27 subunit beta isoform X1 [KO:K24476]
103661231  IL31; interleukin-31 [KO:K22631]
103679513  CLCF1; cardiotrophin-like cytokine factor 1 isoform X1 [KO:K05421]
103666137  CNTF; ciliary neurotrophic factor [KO:K05420]
121103759  LOW QUALITY PROTEIN: cardiotrophin-1-like [KO:K05422]
103657877  cardiotrophin-2 [KO:K24382]
103681125  LIF; leukemia inhibitory factor [KO:K05419]
103681110  OSM; oncostatin-M isoform X1 [KO:K05418]
103657674  IL10; interleukin-10 [KO:K05443]
103657672  IL19; interleukin-19 [KO:K05444]
103657755  IL20; interleukin-20 isoform X1 [KO:K22667]
103657671  IL24; interleukin-24 [KO:K22668]
103656860  IL22; interleukin-22 [KO:K05445]
103656859  IL26; interleukin-26 [KO:K05446]
103661082  interferon lambda-3 [KO:K22669]
103661020  LOW QUALITY PROTEIN: interferon lambda-1 [KO:K05447]
103662147  interferon alpha-1/2-like [KO:K05414]
103662148  interferon alpha-1/2-like [KO:K05414]
103662149  interferon alpha-2-like [KO:K05414]
103680385  interferon alpha-1/2-like [KO:K05414]
103680386  interferon alpha-1/2-like [KO:K05414]
103666985  interferon alpha-1/2-like [KO:K05414]
121103043  interferon alpha-1/2-like [KO:K05414]
103662150  IFNB1; interferon beta [KO:K05415]
103667005  IFNK; interferon kappa [KO:K05441]
103666986  IFNE; interferon epsilon [KO:K05442]
103656858  IFNG; interferon gamma [KO:K04687]
103671864  IL1A; interleukin-1 alpha [KO:K04383]
103671495  IL1B; interleukin-1 beta isoform X2 [KO:K04519]
103671490  interleukin-1 receptor antagonist protein isoform X1 [KO:K05481]
103671492  interleukin-36 receptor antagonist protein [KO:K05483]
103671863  IL36B; interleukin-36 beta [KO:K05486]
103671493  IL36G; interleukin-36 gamma [KO:K05487]
103671491  IL1F10; interleukin-1 family member 10 [KO:K05488]
103662382  IL18; interleukin-18 [KO:K05482]
103662207  IL33; interleukin-33 isoform X1 [KO:K12967]
103664129  IL17A; interleukin-17A [KO:K05489]
103664010  IL17F; interleukin-17F isoform X1 [KO:K05494]
103664610  IL17B; interleukin-17B [KO:K05490]
103673953  IL17C; interleukin-17C [KO:K05491]
103664391  IL17D; interleukin-17D [KO:K05492]
103681047  IL25; interleukin-25 [KO:K05493]
103660290  IL16; pro-interleukin-16 isoform X3 [KO:K22628]
103668513  IL32; interleukin-32 [KO:K22632]
103673577  IL34; interleukin-34 isoform X1 [KO:K22633]
103675205  CSF1; macrophage colony-stimulating factor 1 [KO:K05453]
103682322  TNF; tumor necrosis factor [KO:K03156]
103682323  LTA; lymphotoxin-alpha [KO:K05468]
103682317  LTB; lymphotoxin-beta isoform X1 [KO:K03157]
103681870  TNFSF14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
103668115  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
103670390  TNFSF15; tumor necrosis factor ligand superfamily member 15 isoform X2 [KO:K05478]
103676141  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1 [KO:K04721]
103682605  ectodysplasin-A [KO:K05480]
103669449  NGF; beta-nerve growth factor [KO:K02582]
103677566  TNFSF11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
121102615  tumor necrosis factor ligand superfamily member 12 isoform X1 [KO:K05474]
103681712  CD70; CD70 antigen [KO:K05470]
103670387  TNFSF8; tumor necrosis factor ligand superfamily member 8 [KO:K05471]
103672841  CD40LG; CD40 ligand [KO:K03161]
103681711  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
103668124  TNFSF4; tumor necrosis factor ligand superfamily member 4 [KO:K05469]
103668134  TNFSF18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
103660360  TNFSF13; tumor necrosis factor ligand superfamily member 13 isoform X1 [KO:K05475]
103657543  TNFSF13B; tumor necrosis factor ligand superfamily member 13B [KO:K05476]
103677394  TGFB1; transforming growth factor beta-1 proprotein isoform X1 [KO:K13375]
103658194  TGFB2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376]
103670922  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
103675159  growth/differentiation factor 15 [KO:K05504]
103668056  GDF2; growth/differentiation factor 2 [KO:K05503]
103671354  BMP10; bone morphogenetic protein 10 [KO:K22670]
103662737  INHA; inhibin alpha chain [KO:K05500]
103665414  BMP3; bone morphogenetic protein 3 [KO:K05496]
103668057  GDF10; growth/differentiation factor 10 [KO:K22674]
103656924  GDF11; LOW QUALITY PROTEIN: growth/differentiation factor 11 [KO:K22679]
103659674  MSTN; growth/differentiation factor 8 [KO:K05497]
103674587  INHBA; inhibin beta A chain [KO:K04667]
103658626  INHBB; inhibin beta B chain [KO:K22687]
121102514  GDF1; embryonic growth/differentiation factor 1 [KO:K05495]
103669185  GDF3; growth/differentiation factor 3 [KO:K22672]
103667794  NODAL; nodal homolog [KO:K04666]
103663828  GDF9; growth/differentiation factor 9 isoform X1 [KO:K22673]
103656558  INHBC; inhibin beta C chain [KO:K22688]
103656569  INHBE; inhibin beta E chain [KO:K22689]
121102581  AMH; LOW QUALITY PROTEIN: muellerian-inhibiting factor [KO:K04665]
103674423  BMP2; bone morphogenetic protein 2 isoform X1 [KO:K21283]
103672975  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
103669911  GDF5; growth/differentiation factor 5 [KO:K04664]
103661630  GDF6; growth/differentiation factor 6 [KO:K20012]
121100971  GDF7; growth/differentiation factor 7 [KO:K20013]
103661936  bone morphogenetic protein 15 [KO:K05498]
103663983  BMP5; bone morphogenetic protein 5 isoform X1 [KO:K04663]
103665146  BMP6; bone morphogenetic protein 6 [KO:K16620]
103670970  BMP7; bone morphogenetic protein 7 isoform X1 [KO:K16621]
103682405  LOW QUALITY PROTEIN: bone morphogenetic protein 8B-like [KO:K16622]
103666706  BMP8A; bone morphogenetic protein 8A [KO:K16622]
103680537  CCR8; C-C chemokine receptor type 8 [KO:K04183]
103674895  CCR9; C-C chemokine receptor type 9 [KO:K04184]
103679094  ACKR4; atypical chemokine receptor 4 [KO:K04186]
103661820  CCR7; C-C chemokine receptor type 7 isoform X2 [KO:K04182]
103680999  CCR4; C-C chemokine receptor type 4 [KO:K04179]
103674885  CCR5; C-C chemokine receptor type 5 [KO:K04180]
103674890  C-C chemokine receptor type 3 isoform X2 [KO:K04178]
103674886  CCR2; C-C chemokine receptor type 2 [KO:K04177]
103674891  C-C chemokine receptor type 1 isoform X1 [KO:K04176]
103672626  CCR10; C-C chemokine receptor type 10 [KO:K04185]
103660805  CCR6; C-C chemokine receptor type 6 [KO:K04181]
103662893  CXCR1; C-X-C chemokine receptor type 1 [KO:K04175]
103662772  C-X-C chemokine receptor type 2 [KO:K05050]
121102893  CXCR3; C-X-C chemokine receptor type 3 isoform X1 [KO:K04188]
103662324  CXCR5; C-X-C chemokine receptor type 5 [KO:K04190]
103667676  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
103662644  ACKR3; atypical chemokine receptor 3 [KO:K04304]
103674896  CXCR6; C-X-C chemokine receptor type 6 [KO:K04191]
103674894  XCR1; chemokine XC receptor 1 [KO:K04193]
103680546  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
103676245  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
103676409  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
103682591  IL2RG; cytokine receptor common subunit gamma isoform X1 [KO:K05070]
103657902  IL4R; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
103664716  IL7R; interleukin-7 receptor subunit alpha isoform X1 [KO:K05072]
103676865  LOW QUALITY PROTEIN: interleukin-9 receptor-like [KO:K05073]
103668438  IL9R; interleukin-9 receptor isoform X1 [KO:K05073]
103676282  IL15RA; LOW QUALITY PROTEIN: interleukin-15 receptor subunit alpha [KO:K05074]
103657903  IL21R; interleukin-21 receptor [KO:K05075]
103666288  CRLF2; cytokine receptor-like factor 2 [KO:K05078]
103666330  IL3RA; interleukin-3 receptor subunit alpha [KO:K04737]
103676415  CSF2RB; cytokine receptor common subunit beta [KO:K04738]
103674266  IL5RA; interleukin-5 receptor subunit alpha isoform X1 [KO:K05067]
103666290  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1 [KO:K05066]
103666329  granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like [KO:K05066]
103677732  IL13RA1; interleukin-13 receptor subunit alpha-1 isoform X1 [KO:K05076]
103679731  IL13RA2; interleukin-13 receptor subunit alpha-2 [KO:K05077]
103678709  EPOR; erythropoietin receptor isoform X1 [KO:K05079]
103664663  GHR; growth hormone receptor isoform X1 [KO:K05080]
103664719  PRLR; prolactin receptor [KO:K05081]
103670908  MPL; thrombopoietin receptor isoform X1 [KO:K05082]
103666378  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
103663045  LEPR; leptin receptor isoform X1 [KO:K05062]
103668717  IL6R; interleukin-6 receptor subunit alpha isoform X1 [KO:K05055]
103663669  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
103667059  IL11RA; interleukin-11 receptor subunit alpha isoform X1 [KO:K05056]
103674947  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
103663034  IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1 [KO:K05064]
103663036  IL23R; interleukin-23 receptor [KO:K05065]
103682129  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
103663670  IL31RA; interleukin-31 receptor subunit alpha [KO:K22630]
103667051  CNTFR; ciliary neurotrophic factor receptor subunit alpha isoform X1 [KO:K05059]
103664694  LIFR; leukemia inhibitory factor receptor [KO:K05058]
103664690  OSMR; oncostatin-M-specific receptor subunit beta isoform X1 [KO:K05057]
103662345  IL10RA; interleukin-10 receptor subunit alpha [KO:K05134]
121099743  IL10RB; interleukin-10 receptor subunit beta [KO:K05135]
103663373  IL20RA; interleukin-20 receptor subunit alpha [KO:K05136]
103678770  IL20RB; interleukin-20 receptor subunit beta [KO:K05137]
103666549  IL22RA1; interleukin-22 receptor subunit alpha-1 [KO:K05138]
103666548  IFNLR1; interferon lambda receptor 1 [KO:K05140]
103673220  IFNAR1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
103673110  IFNAR2; interferon alpha/beta receptor 2 isoform X2 [KO:K05131]
103663370  IFNGR1; interferon gamma receptor 1 [KO:K05132]
103673221  IFNGR2; interferon gamma receptor 2 [KO:K05133]
103670641  IL1R1; interleukin-1 receptor type 1 isoform X1 [KO:K04386]
103676019  interleukin-1 receptor accessory protein isoform X2 [KO:K04723]
103670643  IL1R2; interleukin-1 receptor type 2 isoform X1 [KO:K04387]
103670639  IL1RL2; interleukin-1 receptor-like 2 [KO:K05172]
103670637  IL18R1; interleukin-18 receptor 1 isoform X1 [KO:K05173]
103670635  interleukin-18 receptor accessory protein isoform X1 [KO:K05174]
103670638  IL1RL1; interleukin-1 receptor-like 1 isoform X1 [KO:K05171]
103675703  IL17RA; interleukin-17 receptor A [KO:K05164]
103669567  IL17RC; interleukin-17 receptor C isoform X2 [KO:K05166]
103674732  IL17RB; interleukin-17 receptor B isoform X2 [KO:K05165]
103669646  IL17RE; interleukin-17 receptor E isoform X1 [KO:K05168]
103656225  CD4; T-cell surface glycoprotein CD4 isoform X1 [KO:K06454]
103664603  CSF1R; macrophage colony-stimulating factor 1 receptor isoform X1 [KO:K05090] [EC:2.7.10.1]
103656234  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
103666853  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X1 [KO:K05141]
103656207  LTBR; tumor necrosis factor receptor superfamily member 3 isoform X1 [KO:K03159]
103678434  TNFRSF14; tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
103660558  TNFRSF6B; tumor necrosis factor receptor superfamily member 6B [KO:K05143]
103661934  FAS; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
103666695  TNFRSF25; tumor necrosis factor receptor superfamily member 25 isoform X1 [KO:K05160]
103671065  tumor necrosis factor receptor superfamily member 1A-like isoform X1 [KO:K04722]
103664138  TNFRSF21; tumor necrosis factor receptor superfamily member 21 [KO:K05157]
103682573  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X1 [KO:K05162]
103681147  EDA2R; tumor necrosis factor receptor superfamily member 27 isoform X1 [KO:K05163]
103661017  NGFR; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
103661589  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
103676207  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A [KO:K05147]
103668802  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A [KO:K05149]
103656203  CD27; CD27 antigen isoform X1 [KO:K05144]
103666854  TNFRSF8; tumor necrosis factor receptor superfamily member 8 [KO:K05145]
103669702  CD40; tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K03160]
103666689  TNFRSF9; tumor necrosis factor receptor superfamily member 9 isoform X1 [KO:K05146]
103682081  TNFRSF4; tumor necrosis factor receptor superfamily member 4 isoform X1 [KO:K05142]
103682082  TNFRSF18; tumor necrosis factor receptor superfamily member 18 isoform X1 [KO:K05154]
103668610  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
103658485  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B [KO:K05150]
103674152  TNFRSF13C; tumor necrosis factor receptor superfamily member 13C isoform X1 [KO:K05151]
103664298  TNFRSF19; tumor necrosis factor receptor superfamily member 19 isoform X1 [KO:K05155]
103678115  RELT; tumor necrosis factor receptor superfamily member 19L [KO:K05156]
103663722  RELL2; RELT-like protein 2 [KO:K26541]
103672655  RELL1; RELT-like protein 1 [KO:K26541]
103678627  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
103682015  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
103675498  ACVRL1; serine/threonine-protein kinase receptor R3 [KO:K13594] [EC:2.7.11.30]
103667704  ACVR2A; activin receptor type-2A [KO:K04670] [EC:2.7.11.30]
103659757  BMPR2; bone morphogenetic protein receptor type-2 [KO:K04671] [EC:2.7.11.30]
103680677  ACVR2B; activin receptor type-2B [KO:K13596] [EC:2.7.11.30]
103675499  ACVR1B; activin receptor type-1B isoform X1 [KO:K13567] [EC:2.7.11.30]
103659481  ACVR1C; activin receptor type-1C [KO:K13568] [EC:2.7.11.30]
103659482  ACVR1; activin receptor type-1 [KO:K04675] [EC:2.7.11.30]
103675532  AMHR2; anti-Muellerian hormone type-2 receptor [KO:K04672] [EC:2.7.11.30]
103667882  BMPR1A; bone morphogenetic protein receptor type-1A [KO:K04673] [EC:2.7.11.30]
103677908  BMPR1B; bone morphogenetic protein receptor type-1B isoform X2 [KO:K13578] [EC:2.7.11.30]
Reference
PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
PMID:21106488
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
PMID:27577879
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
PMID:15500860
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
PMID:16034365
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
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