KEGG   PATHWAY: vpc04024
Entry
vpc04024                    Pathway                                
Name
cAMP signaling pathway - Vicugna pacos (alpaca)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
vpc04024  cAMP signaling pathway
vpc04024

Other DBs
GO: 0019933
Organism
Vicugna pacos (alpaca) [GN:vpc]
Gene
102529527  VIP; VIP peptides [KO:K05264]
102530101  CRH; corticoliberin isoform X2 [KO:K05256]
102541684  CGA; glycoprotein hormones alpha chain [KO:K08522]
102542235  lutropin subunit beta [KO:K08521]
102544466  GPHA2; glycoprotein hormone alpha-2 [KO:K25483]
102528883  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
102535863  TSHB; thyrotropin subunit beta [KO:K05251]
102542487  GCG; glucagon isoform X1 [KO:K05259]
102543834  GIP; gastric inhibitory polypeptide isoform X1 [KO:K05258]
102530834  FSHB; follitropin subunit beta [KO:K05250]
102533440  NPPA; natriuretic peptides A [KO:K12334]
102540817  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
116282527  ADRB1; beta-1 adrenergic receptor [KO:K04141]
102527743  ADRB2; beta-2 adrenergic receptor [KO:K04142]
102535792  DRD1; D(1A) dopamine receptor [KO:K04144]
102524750  DRD5; D(1B) dopamine receptor [KO:K05840]
102544615  ADORA2A; adenosine receptor A2a [KO:K04266]
102528004  HTR4; 5-hydroxytryptamine receptor 4 isoform X1 [KO:K04160]
102542903  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
102532574  PTGER2; prostaglandin E2 receptor EP2 subtype isoform X1 [KO:K04259]
102545179  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
102527109  CRHR1; corticotropin-releasing factor receptor 1 isoform X2 [KO:K04578]
102543610  CRHR2; corticotropin-releasing factor receptor 2 isoform X3 [KO:K04579]
102540092  LHCGR; lutropin-choriogonadotropic hormone receptor [KO:K04248]
102542465  TSHR; thyrotropin receptor isoform X1 [KO:K04249]
102533695  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
102533730  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
102538929  GIPR; LOW QUALITY PROTEIN: gastric inhibitory polypeptide receptor [KO:K04580]
102526112  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
102536117  FSHR; follicle-stimulating hormone receptor isoform X1 [KO:K04247]
102537431  NPR1; atrial natriuretic peptide receptor 1 isoform X3 [KO:K12323] [EC:4.6.1.2]
102528916  GNAS; LOW QUALITY PROTEIN: neuroendocrine secretory protein 55 [KO:K04632]
102533381  LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas [KO:K04632]
102528569  EDN1; endothelin-1 [KO:K16366]
102524743  EDN2; endothelin-2 [KO:K16367]
102529705  EDN3; endothelin-3 [KO:K05227]
102527186  SST; somatostatin [KO:K05237]
102533397  NPY; pro-neuropeptide Y [KO:K05232]
102525630  GHRL; appetite-regulating hormone isoform X1 [KO:K05254]
116279141  OXT; oxytocin-neurophysin 1 [KO:K05243]
102537106  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
102531828  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
102536594  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
102533774  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
102541935  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
102534636  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
102543989  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
102529763  DRD2; D(2) dopamine receptor isoform X2 [KO:K04145]
102531423  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 isoform X5 [KO:K04615]
102526877  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 isoform X3 [KO:K04615]
102538982  ADORA1; adenosine receptor A1 isoform X2 [KO:K04265]
102532545  EDNRA; endothelin-1 receptor [KO:K04197]
102536299  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
102538620  SSTR1; somatostatin receptor type 1 isoform X1 [KO:K04217]
102524640  SSTR2; somatostatin receptor type 2 [KO:K04218]
102539086  SSTR5; somatostatin receptor type 5 [KO:K04221]
102544691  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
102544964  hydroxycarboxylic acid receptor 2 [KO:K08402]
102532330  FFAR2; free fatty acid receptor 2 [KO:K04328]
102527456  SUCNR1; succinate receptor 1 [KO:K10042]
102525936  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X3 [KO:K04260]
102538136  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
102543440  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [KO:K04630]
102541755  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
102525399  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
102538400  ADCY1; LOW QUALITY PROTEIN: adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
102539698  ADCY2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
102536207  ADCY3; adenylate cyclase type 3 isoform X5 [KO:K08043] [EC:4.6.1.1]
102544207  ADCY4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
102534219  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
102532587  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
102529498  ADCY7; adenylate cyclase type 7 isoform X2 [KO:K08047] [EC:4.6.1.1]
102543885  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
102535401  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
107033357  adenylate cyclase type 10-like isoform X11 [KO:K11265] [EC:4.6.1.1]
102525312  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
102543009  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
102529090  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
102540388  CNGA3; cyclic nucleotide-gated cation channel alpha-3 isoform X1 [KO:K04950]
102533996  CNGA4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
102535198  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
102530347  CNGB3; cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
102531096  CALM2; calmodulin-2 [KO:K02183]
102539425  CALM1; calmodulin-1 [KO:K02183]
102544854  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
102532310  calmodulin-like [KO:K02183]
102533842  CALM3; calmodulin-3 [KO:K02183]
102542241  CALML5; calmodulin-like protein 5 [KO:K02183]
102543778  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3 [KO:K04515] [EC:2.7.11.17]
102536144  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
102541361  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma [KO:K04515] [EC:2.7.11.17]
102544405  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
102539084  CAMK4; calcium/calmodulin-dependent protein kinase type IV isoform X2 [KO:K05869] [EC:2.7.11.17]
102536866  BVES; blood vessel epicardial substance isoform X2 [KO:K21108]
102539267  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
102536629  POPDC3; popeye domain-containing protein 3 [KO:K26207]
102535203  KCNK2; potassium channel subfamily K member 2 isoform X2 [KO:K04913]
102531877  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
102535780  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
102534928  ABCC4; multidrug resistance-associated protein 4 isoform X1 [KO:K05673]
102527378  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
102528724  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X3 [KO:K04351]
102526809  RRAS; ras-related protein R-Ras [KO:K07829]
102535239  RRAS2; ras-related protein R-Ras2 [KO:K07830]
102537789  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
102538815  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
102542888  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
102528221  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
102543430  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
102539859  MAPK10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
102544212  RAP1A; ras-related protein Rap-1A [KO:K04353]
102535500  RAP1B; ras-related protein Rap-1b [KO:K07836]
102527012  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 [KO:K05731]
102539556  VAV2; guanine nucleotide exchange factor VAV2 [KO:K05730]
102526475  VAV3; guanine nucleotide exchange factor VAV3 [KO:K05730]
102544949  VAV1; proto-oncogene vav [KO:K05730]
102543993  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
102541733  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
102545613  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
102543166  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
102538920  ARAP3; LOW QUALITY PROTEIN: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 [KO:K12490]
102534196  RHOA; transforming protein RhoA [KO:K04513]
102524829  AFDN; afadin [KO:K05702]
102540289  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
102524821  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
102543068  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
102532395  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
102536302  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
102536225  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
102526860  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102546009  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102542031  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102528789  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
102543308  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
102530118  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
102534668  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
102536713  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
102528720  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
102528179  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
102534902  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
102534257  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X3 [KO:K06269] [EC:3.1.3.16]
102532474  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
102536752  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
102531048  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
102544965  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
102534415  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
102538690  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
102534951  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1 [KO:K09048]
102541872  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
102540303  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X5 [KO:K09047]
102531948  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
102535153  CREBBP; LOW QUALITY PROTEIN: CREB-binding protein [KO:K04498] [EC:2.3.1.48]
102532564  BDNF; LOW QUALITY PROTEIN: brain-derived neurotrophic factor [KO:K04355]
102533186  FOS; proto-oncogene c-Fos [KO:K04379]
102541687  JUN; LOW QUALITY PROTEIN: transcription factor AP-1 [KO:K04448]
102539046  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
102525352  GLI1; zinc finger protein GLI1 [KO:K16797]
102525054  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
102529682  HHIP; hedgehog-interacting protein [KO:K06231]
102524630  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
102532161  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
102540197  RELA; transcription factor p65 isoform X1 [KO:K04735]
102545677  SOX9; LOW QUALITY PROTEIN: transcription factor SOX-9 [KO:K18435]
102543134  AMH; muellerian-inhibiting factor [KO:K04665]
102527411  PPARA; peroxisome proliferator-activated receptor alpha [KO:K07294]
102536864  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X2 [KO:K00232] [EC:1.3.3.6]
102537847  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 [KO:K00232] [EC:1.3.3.6]
102543250  NFATC1; LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 1 [KO:K04446]
102544814  F2R; proteinase-activated receptor 1 [KO:K03914]
102538813  BAD; bcl2-associated agonist of cell death isoform X2 [KO:K02158]
102531302  LIPE; hormone-sensitive lipase isoform X6 [KO:K07188] [EC:3.1.1.79]
102539343  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
102524824  ROCK2; rho-associated protein kinase 2 isoform X8 [KO:K17388] [EC:2.7.11.1]
102539445  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X5 [KO:K06270]
102530350  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
102524999  TNNI3; troponin I, cardiac muscle isoform X1 [KO:K12044]
102526032  PLN; cardiac phospholamban [KO:K05852]
102537306  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1 [KO:K05853] [EC:7.2.2.10]
102528424  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [KO:K05853] [EC:7.2.2.10]
102532821  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
102537530  RYR2; ryanodine receptor 2 [KO:K04962]
102542783  GRIN1; glutamate receptor ionotropic, NMDA 1 [KO:K05208]
102528001  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
102537026  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
102527963  GRIN2C; glutamate receptor ionotropic, NMDA 2C [KO:K05211]
102532699  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
102543122  GRIN3A; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
102529035  GRIN3B; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
102529534  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
102542018  GRIA2; glutamate receptor 2 isoform X3 [KO:K05198]
102544562  GRIA3; glutamate receptor 3 isoform X1 [KO:K05199]
102539059  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
102527896  CFTR; LOW QUALITY PROTEIN: cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
102529041  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
102537426  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
102542176  sodium/potassium-transporting ATPase subunit alpha-2 isoform X1 [KO:K01539] [EC:7.2.2.13]
102542760  sodium/potassium-transporting ATPase subunit alpha-4 [KO:K01539] [EC:7.2.2.13]
102541677  ATP1B4; protein ATP1B4 isoform X1 [KO:K01540]
102530700  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
102527589  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
102525104  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
116276751  FXYD2; sodium/potassium-transporting ATPase subunit gamma isoform X1 [KO:K01538]
102531731  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
102534427  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
102536572  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
102529013  ATP2B3; LOW QUALITY PROTEIN: plasma membrane calcium-transporting ATPase 3 [KO:K05850] [EC:7.2.2.10]
102525650  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X2 [KO:K05850] [EC:7.2.2.10]
102542706  ATP2B2; plasma membrane calcium-transporting ATPase 2 [KO:K05850] [EC:7.2.2.10]
102538871  CACNA1C; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1C [KO:K04850]
102539274  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
102540844  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
102528399  CACNA1S; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
102544834  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
102541993  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1 [KO:K13296] [EC:3.1.4.17]
102540080  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
102529494  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X4 [KO:K13293] [EC:3.1.4.53]
102535549  PDE4C; LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
102534504  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
102544279  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X7 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
Pharmaceuticals (Basel) 5:1291-331 (2012)
DOI:10.3390/ph5121291
Reference
PMID:24613710
  Authors
Ahuja M, Jha A, Maleth J, Park S, Muallem S
  Title
cAMP and Ca signaling in secretory epithelia: Crosstalk and synergism.
  Journal
Cell Calcium 55:385-393 (2014)
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Related
pathway
vpc00071  Fatty acid degradation
vpc04015  Rap1 signaling pathway
vpc04020  Calcium signaling pathway
vpc04151  PI3K-Akt signaling pathway
vpc04210  Apoptosis
vpc04260  Cardiac muscle contraction
vpc04340  Hedgehog signaling pathway
vpc04720  Long-term potentiation
vpc04740  Olfactory transduction
vpc04972  Pancreatic secretion
vpc04976  Bile secretion
KO pathway
ko04024   
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