KEGG   ORTHOLOGY: K04721
Entry
K04721                      KO                                     

Name
TNFSF10, TRAIL, CD253
Definition
tumor necrosis factor ligand superfamily member 10
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04068  FoxO signaling pathway
map04210  Apoptosis
map04217  Necroptosis
map04650  Natural killer cell mediated cytotoxicity
map05130  Pathogenic Escherichia coli infection
map05132  Salmonella infection
map05164  Influenza A
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04061 Viral protein interaction with cytokine and cytokine receptor
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04217 Necroptosis
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   05132 Salmonella infection
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04052 Cytokines and growth factors
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04090 CD molecules
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Tumor necrosis fators
   K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
CD molecules [BR:ko04090]
 Proteins
  K04721  CD253, TNFSF10; tumor necrosis factor (ligand) superfamily, member 10
Other DBs
GO: 0005164
Genes
HSA: 8743(TNFSF10)
PTR: 460852(TNFSF10)
PPS: 100986991(TNFSF10)
PON: 100441526(TNFSF10)
MCC: 694451(TNFSF10)
MCF: 101864918(TNFSF10)
CSAB: 103221246(TNFSF10)
CATY: 105586081(TNFSF10)
PANU: 101016626(TNFSF10)
RRO: 104657165(TNFSF10)
RBB: 108540415(TNFSF10)
TFN: 117083738(TNFSF10)
PTEH: 111543475(TNFSF10)
CJC: 100396000(TNFSF10)
SBQ: 101030281(TNFSF10)
MMUR: 105855430(TNFSF10)
MMU: 22035(Tnfsf10)
MCAL: 110291484(Tnfsf10)
MPAH: 110320972(Tnfsf10)
RNO: 246775(Tnfsf10)
MCOC: 116095017(Tnfsf10)
CGE: 100754968(Tnfsf10)
PLEU: 114697551(Tnfsf10)
NGI: 103739879(Tnfsf10)
HGL: 101702439(Tnfsf10)
CCAN: 109683456
OCU: 100355808(TNFSF10)
TUP: 102501703(TNFSF10)
CFA: 100174780(TNFSF10)
VVP: 112926677(TNFSF10)
VLG: 121477409(TNFSF10)
AML: 100463573(TNFSF10)
UMR: 103676141(TNFSF10)
UAH: 113255024(TNFSF10)
ORO: 101371152(TNFSF10)
ELK: 111152154
MPUF: 101675328(TNFSF10)
EJU: 114207003(TNFSF10)
MLX: 118006404(TNFSF10)
FCA: 100174789(TNFSF10)
PTG: 102963342(TNFSF10)
PPAD: 109275136(TNFSF10)
AJU: 106990055(TNFSF10)
HHV: 120234588(TNFSF10)
BTA: 507215(TNFSF10)
BOM: 102287110(TNFSF10)
BIU: 109558018(TNFSF10)
BBUB: 102402214(TNFSF10)
CHX: 102173335(TNFSF10)
OAS: 101114153(TNFSF10)
ODA: 120869589(TNFSF10)
SSC: 406191(TNFSF10)
CFR: 102506160(TNFSF10)
CDK: 105085942(TNFSF10)
BACU: 102997406(TNFSF10)
LVE: 103083521(TNFSF10)
OOR: 101282902(TNFSF10)
DLE: 111173963(TNFSF10)
PCAD: 102992913(TNFSF10)
ECB: 100064377(TNFSF10)
EPZ: 103546356(TNFSF10)
EAI: 106847522(TNFSF10)
MYB: 102262545(TNFSF10)
MYD: 102751425(TNFSF10)
MMYO: 118676101(TNFSF10)
MNA: 107533523(TNFSF10)
HAI: 109371673(TNFSF10)
DRO: 112307528(TNFSF10)
SHON: 118987393(TNFSF10)
AJM: 119043451(TNFSF10)
MMF: 118617099(TNFSF10)
PALE: 102885663(TNFSF10)
RAY: 107516234(TNFSF10)
MJV: 108383372(TNFSF10)
TOD: 119257290(TNFSF10)
LAV: 100659733(TNFSF10)
TMU: 101359129
MDO: 100010299(TNFSF10)
SHR: 105750042(TNFSF10)
PCW: 110204161(TNFSF10)
OAA: 100074849(TNFSF10)
GGA: 378894(TNFSF10)
PCOC: 116243372(TNFSF10)
MGP: 100550143(TNFSF10)
CJO: 107318308(TNFSF10)
NMEL: 110398962(TNFSF10)
APLA: 101797713(TNFSF10)
ACYG: 106031999(TNFSF10)
TGU: 100227931(TNFSF10)
LSR: 110480362(TNFSF10)
SCAN: 103815595(TNFSF10)
PMOA: 120504333(TNFSF10)
GFR: 102042782(TNFSF10)
FAB: 101806118(TNFSF10)
PHI: 102100672(TNFSF10)
PMAJ: 107208991(TNFSF10)
CCAE: 111933337(TNFSF10)
CCW: 104688035(TNFSF10)
ETL: 114061190(TNFSF10)
FPG: 101922846(TNFSF10)
FCH: 102047699(TNFSF10)
CLV: 102093335(TNFSF10)
EGZ: 104132497(TNFSF10)
NNI: 104022070(TNFSF10)
ACUN: 113483422(TNFSF10)
PADL: 103924981(TNFSF10)
AAM: 106486566(TNFSF10)
ASN: 102371031(TNFSF10)
AMJ: 102576971(TNFSF10)
CPOO: 109308442(TNFSF10)
GGN: 109287988(TNFSF10)
PSS: 102460636(TNFSF10)
CMY: 102945208(TNFSF10)
CPIC: 101952595(TNFSF10)
TST: 117882806(TNFSF10)
CABI: 116826739(TNFSF10)
ACS: 100566541(tnfsf10)
PVT: 110079056(TNFSF10)
PBI: 103056379(TNFSF10)
PMUR: 107286546(TNFSF10)
TSR: 106547753(TNFSF10)
PGUT: 117678186(TNFSF10)
PMUA: 114597986(TNFSF10)
ZVI: 118093614(TNFSF10)
GJA: 107113859(TNFSF10)
XLA: 100316914(tnfsf10.S) 108717006(tnfsf10.L)
XTR: 100493578(tnfsf10)
NPR: 108784823(TNFSF10)
DRE: 436866(tnfsf10)
TRU: 100653422(tnfsf10) 101061420
PLEP: 121953865 121960904(tnfsf10)
SLUC: 116040032(tnfsf10) 116057709
GAT: 120832843(tnfsf10)
CUD: 121525816 121527724(tnfsf10)
OLA: 101156131(tnfsf10) 101172365
XHE: 116711469
CVG: 107085098(tnfsf10) 107103203
NFU: 107383107 107392066(tnfsf10)
KMR: 108234661(tnfsf10) 108247980
ALIM: 106522312 106525539(tnfsf10) 106534382
CSEM: 103377512 103378994(tnfsf10)
LCF: 108875098(tnfsf10) 108885067 108902513(tnfsf11)
SLAL: 111651407 111665906(tnfsf10)
XGL: 120790035(tnfsf10) 120795438
ELS: 105022065
LOC: 102695414(tnfsf10) 107077552
LCM: 102345421(TNFSF10)
CMK: 103177380 103190454(tnfsf10)
SCLV: 120328846
SPU: 100891737
OBI: 106873185
ATEN: 116302515
AMIL: 114952948
DGT: 114535243
 » show all
Reference
PMID:8777713
  Authors
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA, et al.
  Title
Identification and characterization of a new member of the TNF family that induces apoptosis.
  Journal
Immunity 3:673-82 (1995)
DOI:10.1016/1074-7613(95)90057-8
  Sequence
[hsa:8743]
Reference
  Authors
McGrath EE, Marriott HM, Lawrie A, Francis SE, Sabroe I, Renshaw SA, Dockrell DH, Whyte MK
  Title
TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation.
  Journal
J Leukoc Biol 90:855-65 (2011)
DOI:10.1189/jlb.0211062
  Sequence
[mmu:22035]
LinkDB

DBGET integrated database retrieval system