Homo sapiens (human): 727 Help Entry 727               CDS       T01001                                  Symbol C5, C5D, C5a, C5b, CPAMD4, ECLZB Name (RefSeq) complement C5   KO K03994   complement component 5 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04610   Complement and coagulation cascades hsa04613   Neutrophil extracellular trap formation hsa04810   Regulation of actin cytoskeleton hsa04936   Alcoholic liver disease hsa05020   Prion disease hsa05133   Pertussis hsa05150   Staphylococcus aureus infection hsa05168   Herpes simplex virus 1 infection hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation Disease H00103   Late complement pathway defects Drug target Avacincaptad pegol:  D11748<US> Crovalimab:  D11696<JP/US> Eculizumab:  D03940<JP/US> Gefurulimab:  D12208 Nomacopan:  D11473 Olendalizumab:  D11331 Pexelizumab:  D10023 Pozelimab:  D11477<US> Ravulizumab:  D11054<JP/US> Vilobelimab:  D11838<US> Zilucoplan (DG03224):  D12356<JP/US> D12357 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     727 (C5)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     727 (C5)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     727 (C5)    04613 Neutrophil extracellular trap formation     727 (C5)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     727 (C5)    05168 Herpes simplex virus 1 infection     727 (C5)   09171 Infectious disease: bacterial    05133 Pertussis     727 (C5)    05150 Staphylococcus aureus infection     727 (C5)   09163 Immune disease    05322 Systemic lupus erythematosus     727 (C5)   09164 Neurodegenerative disease    05020 Prion disease     727 (C5)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     727 (C5)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     727 (C5) Peptidases and inhibitors [BR:hsa01002]  Peptidase inhibitors   Family I39: alpha2M family    727 (C5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TED_complement A2M_BRD MG1 A2M C5_CUB A2M_recep NTR MG4 MG2 MG3 ANATO Motif Other DBs NCBI-GeneID:  727 NCBI-ProteinID:  NP_001726 OMIM:  120900 HGNC:  1331 Ensembl:  ENSG00000106804 CPD:  C16510 C22545 UniProt:  P01031 Structure PDBPDBj LinkDB All DBs Position 9:complement(120952335..121074865) Genome browser AA seq 1676 aa AA seqDB search MGLLGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYP DKKFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPIT YDNGFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHI GIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGY KNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVT FDSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATP LFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASF VLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGE HLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRL LVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATGMDSWV ALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANAD DSQENDEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETCEQRAARISL GPRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLV PRRKQLQFALPDSLTTWEIQGVGISNTGICVADTVKAKVFKDVFLEMNIPYSVVRGEQIQ LKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTFTV LPLEIGLHNINFSLETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFP YRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFY VFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSASTWLTA FALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEAREN SLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDK THPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLN LKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHK GALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLK IDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLK ALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHR PDKQCTMFYSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETRKQTACKPEIAYA YKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIM GKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFLANLDEFAEDIFLNGC NT seq 5031 nt NT seq  +upstreamnt  +downstreamnt atgggccttttgggaatactttgttttttaatcttcctggggaaaacctggggacaggag caaacatatgtcatttcagcaccaaaaatattccgtgttggagcatctgaaaatattgtg attcaagtttatggatacactgaagcatttgatgcaacaatctctattaaaagttatcct gataaaaaatttagttactcctcaggccatgttcatttatcctcagagaataaattccaa aactctgcaatcttaacaatacaaccaaaacaattgcctggaggacaaaacccagtttct tatgtgtatttggaagttgtatcaaagcatttttcaaaatcaaaaagaatgccaataacc tatgacaatggatttctcttcattcatacagacaaacctgtttatactccagaccagtca gtaaaagttagagtttattcgttgaatgacgacttgaagccagccaaaagagaaactgtc ttaactttcatagatcctgaaggatcagaagttgacatggtagaagaaattgatcatatt ggaattatctcttttcctgacttcaagattccgtctaatcctagatatggtatgtggacg atcaaggctaaatataaagaggacttttcaacaactggaaccgcatattttgaagttaaa gaatatgtcttgccacatttttctgtctcaatcgagccagaatataatttcattggttac aagaactttaagaattttgaaattactataaaagcaagatatttttataataaagtagtc actgaggctgacgtttatatcacatttggaataagagaagacttaaaagatgatcaaaaa gaaatgatgcaaacagcaatgcaaaacacaatgttgataaatggaattgctcaagtcaca tttgattctgaaacagcagtcaaagaactgtcatactacagtttagaagatttaaacaac aagtacctttatattgctgtaacagtcatagagtctacaggtggattttctgaagaggca gaaatacctggcatcaaatatgtcctctctccctacaaactgaatttggttgctactcct cttttcctgaagcctgggattccatatcccatcaaggtgcaggttaaagattcgcttgac cagttggtaggaggagtcccagtaacactgaatgcacaaacaattgatgtaaaccaagag acatctgacttggatccaagcaaaagtgtaacacgtgttgatgatggagtagcttccttt gtgcttaatctcccatctggagtgacggtgctggagtttaatgtcaaaactgatgctcca gatcttccagaagaaaatcaggccagggaaggttaccgagcaatagcatactcatctctc agccaaagttacctttatattgattggactgataaccataaggctttgctagtgggagaa catctgaatattattgttacccccaaaagcccatatattgacaaaataactcactataat tacttgattttatccaagggcaaaattatccactttggcacgagggagaaattttcagat gcatcttatcaaagtataaacattccagtaacacagaacatggttccttcatcccgactt ctggtctattacatcgtcacaggagaacagacagcagaattagtgtctgattcagtctgg ttaaatattgaagaaaaatgtggcaaccagctccaggttcatctgtctcctgatgcagat gcatattctccaggccaaactgtgtctcttaatatggcaactggaatggattcctgggtg gcattagcagcagtggacagtgctgtgtatggagtccaaagaggagccaaaaagcccttg gaaagagtatttcaattcttagagaagagtgatctgggctgtggggcaggtggtggcctc aacaatgccaatgtgttccacctagctggacttaccttcctcactaatgcaaatgcagat gactcccaagaaaatgatgaaccttgtaaagaaattctcaggccaagaagaacgctgcaa aagaagatagaagaaatagctgctaaatataaacattcagtagtgaagaaatgttgttac gatggagcctgcgttaataatgatgaaacctgtgagcagcgagctgcacggattagttta gggccaagatgcatcaaagctttcactgaatgttgtgtcgtcgcaagccagctccgtgct aatatctctcataaagacatgcaattgggaaggctacacatgaagaccctgttaccagta agcaagccagaaattcggagttattttccagaaagctggttgtgggaagttcatcttgtt cccagaagaaaacagttgcagtttgccctacctgattctctaaccacctgggaaattcaa ggcgttggcatttcaaacactggtatatgtgttgctgatactgtcaaggcaaaggtgttc aaagatgtcttcctggaaatgaatataccatattctgttgtacgaggagaacagatccaa ttgaaaggaactgtttacaactataggacttctgggatgcagttctgtgttaaaatgtct gctgtggagggaatctgcacttcggaaagcccagtcattgatcatcagggcacaaagtcc tccaaatgtgtgcgccagaaagtagagggctcctccagtcacttggtgacattcactgtg cttcctctggaaattggccttcacaacatcaatttttcactggagacttggtttggaaaa gaaatcttagtaaaaacattacgagtggtgccagaaggtgtcaaaagggaaagctattct ggtgttactttggatcctaggggtatttatggtaccattagcagacgaaaggagttccca tacaggatacccttagatttggtccccaaaacagaaatcaaaaggattttgagtgtaaaa ggactgcttgtaggtgagatcttgtctgcagttctaagtcaggaaggcatcaatatccta acccacctccccaaagggagtgcagaggcggagctgatgagcgttgtcccagtattctat gtttttcactacctggaaacaggaaatcattggaacatttttcattctgacccattaatt gaaaagcagaaactgaagaaaaaattaaaagaagggatgttgagcattatgtcctacaga aatgctgactactcttacagtgtgtggaagggtggaagtgctagcacttggttaacagct tttgctttaagagtacttggacaagtaaataaatacgtagagcagaaccaaaattcaatt tgtaattctttattgtggctagttgagaattatcaattagataatggatctttcaaggaa aattcacagtatcaaccaataaaattacagggtaccttgcctgttgaagcccgagagaac agcttatatcttacagcctttactgtgattggaattagaaaggctttcgatatatgcccc ctggtgaaaatcgacacagctctaattaaagctgacaactttctgcttgaaaatacactg ccagcccagagcacctttacattggccatttctgcgtatgctctttccctgggagataaa actcacccacagtttcgttcaattgtttcagctttgaagagagaagctttggttaaaggt aatccacccatttatcgtttttggaaagacaatcttcagcataaagacagctctgtacct aacactggtacggcacgtatggtagaaacaactgcctatgctttactcaccagtctgaac ttgaaagatataaattatgttaacccagtcatcaaatggctatcagaagagcagaggtat ggaggtggcttttattcaacccaggacacaatcaatgccattgagggcctgacggaatat tcactcctggttaaacaactccgcttgagtatggacatcgatgtttcttacaagcataaa ggtgccttacataattataaaatgacagacaagaatttccttgggaggccagtagaggtg cttctcaatgatgacctcattgtcagtacaggatttggcagtggcttggctacagtacat gtaacaactgtagttcacaaaaccagtacctctgaggaagtttgcagcttttatttgaaa atcgatactcaggatattgaagcatcccactacagaggctacggaaactctgattacaaa cgcatagtagcatgtgccagctacaagcccagcagggaagaatcatcatctggatcctct catgcggtgatggacatctccttgcctactggaatcagtgcaaatgaagaagacttaaaa gcccttgtggaaggggtggatcaactattcactgattaccaaatcaaagatggacatgtt attctgcaactgaattcgattccctccagtgatttcctttgtgtacgattccggatattt gaactctttgaagttgggtttctcagtcctgccactttcacagtgtacgaataccacaga ccagataaacagtgtaccatgttttatagcacttccaatatcaaaattcagaaagtctgt gaaggagccgcgtgcaagtgtgtagaagctgattgtgggcaaatgcaggaagaattggat ctgacaatctctgcagagacaagaaaacaaacagcatgtaaaccagagattgcatatgct tataaagttagcatcacatccatcactgtagaaaatgtttttgtcaagtacaaggcaacc cttctggatatctacaaaactggggaagctgttgctgagaaagactctgagattaccttc attaaaaaggtaacctgtactaacgctgagctggtaaaaggaagacagtacttaattatg ggtaaagaagccctccagataaaatacaatttcagtttcaggtacatctaccctttagat tccttgacctggattgaatactggcctagagacacaacatgttcatcgtgtcaagcattt ttagctaatttagatgaatttgccgaagatatctttttaaatggatgctaa

Homo sapiens (human): 729 Help Entry 729               CDS       T01001                                  Symbol C6 Name (RefSeq) complement C6   KO K03995   complement component 6 Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     729 (C6)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     729 (C6)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     729 (C6)   09163 Immune disease    05322 Systemic lupus erythematosus     729 (C6)   09164 Neurodegenerative disease    05020 Prion disease     729 (C6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF Kazal_C6 Sushi TSP_1 EGF_C8A_B_C6 Ldl_recept_a TSP1_spondin Kazal_3 Motif Other DBs NCBI-GeneID:  729 NCBI-ProteinID:  NP_000056 OMIM:  217050 HGNC:  1339 Ensembl:  ENSG00000039537 UniProt:  P13671 Structure PDBPDBj LinkDB All DBs Position 5:complement(41142116..41261469) Genome browser AA seq 934 aa AA seqDB search MARRSVLYFILLNALINKGQACFCDHYAWTQWTSCSKTCNSGTQSRHRQIVVDKYYQENF CEQICSKQETRECNWQRCPINCLLGDFGPWSDCDPCIEKQSKVRSVLRPSQFGGQPCTAP LVAFQPCIPSKLCKIEEADCKNKFRCDSGRCIARKLECNGENDCGDNSDERDCGRTKAVC TRKYNPIPSVQLMGNGFHFLAGEPRGEVLDNSFTGGICKTVKSSRTSNPYRVPANLENVG FEVQTAEDDLKTDFYKDLTSLGHNENQQGSFSSQGGSSFSVPIFYSSKRSENINHNSAFK QAIQASHKKDSSFIRIHKVMKVLNFTTKAKDLHLSDVFLKALNHLPLEYNSALYSRIFDD FGTHYFTSGSLGGVYDLLYQFSSEELKNSGLTEEEAKHCVRIETKKRVLFAKKTKVEHRC TTNKLSEKHEGSFIQGAEKSISLIRGGRSEYGAALAWEKGSSGLEEKTFSEWLESVKENP AVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPTLSGTECL CVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKRSRTRECNNPAPQRGGKR CEGEKRQEEDCTFSIMENNGQPCINDDEEMKEVDLPEIEADSGCPQPVPPENGFIRNEKQ LYLVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQEVLTITPFQR LYRIGESIELTCPKGFVVAGPSRYTCQGNSWTPPISNSLTCEKDTLTKLKGHCQLGQKQS GSECICMSPEEDCSHHSEDLCVFDTDSNDYFTSPACKFLAEKCLNNQQLHFLHIGSCQDG RQLEWGLERTRLSSNSTKKESCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKM GSSTSEKTLNICEVGTIRCANRKMEILHPGKCLA NT seq 2805 nt NT seq  +upstreamnt  +downstreamnt atggccagacgctctgtcttgtacttcatcctgctgaatgctctgatcaacaagggccaa gcctgcttctgtgatcactatgcatggactcagtggaccagctgctcaaaaacttgcaat tctggaacccagagcagacacagacaaatagtagtagataagtactaccaggaaaacttt tgtgaacagatttgcagcaagcaggagactagagaatgtaactggcaaagatgccccatc aactgcctcctgggagattttggaccatggtcagactgtgacccttgtattgaaaaacag tctaaagttagatctgtcttgcgtcccagtcagtttgggggacagccatgcactgcgcct ctggtagcctttcaaccatgcattccatctaagctctgcaaaattgaagaggctgactgc aagaataaatttcgctgtgacagtggccgctgcattgccagaaagttagaatgcaatgga gaaaatgactgtggagacaattcagatgaaagggactgtgggaggacaaaggcagtatgc acacggaagtataatcccatccctagtgtacagttgatgggcaatgggtttcattttctg gcaggagagcccagaggagaagtccttgataactctttcactggaggaatatgtaaaact gtcaaaagcagtaggacaagtaatccataccgtgttccggccaatctggaaaatgtcggc tttgaggtacaaactgcagaagatgacttgaaaacagatttctacaaggatttaacttct cttggacacaatgaaaatcaacaaggctcattctcaagtcagggggggagctctttcagt gtaccaattttttattcctcaaagagaagtgaaaatatcaaccataattctgccttcaaa caagccattcaagcctctcacaaaaaggattctagttttattaggatccataaagtgatg aaagtcttaaacttcacaacgaaagctaaagatctgcacctttctgatgtctttttgaaa gcacttaaccatctgcctctagaatacaactctgctttgtacagccgaatattcgatgac tttgggactcattacttcacctctggctccctgggaggcgtgtatgaccttctctatcag tttagcagtgaggaactaaagaactcaggtttaaccgaggaagaagccaaacactgtgtc aggattgaaacaaagaaacgcgttttatttgctaagaaaacaaaagtggaacataggtgc accaccaacaagctgtcagagaaacatgaaggttcatttatacagggagcagagaaatcc atatccctgattcgaggtggaaggagtgaatatggagcagctttggcatgggagaaaggg agctctggtctggaggagaagacattttctgagtggttagaatcagtgaaggaaaatcct gctgtgattgactttgagcttgcccccatcgtggacttggtaagaaacatcccctgtgca gtgacaaaacggaacaacctcaggaaagctttgcaagagtatgcagccaagttcgatcct tgccagtgtgctccatgccctaataatggccgacccaccctctcagggactgaatgtctg tgtgtgtgtcagagtggcacctatggtgagaactgtgagaaacagtctccagattataaa tccaatgcagtagacggacagtggggttgttggtcttcctggagtacctgtgatgctact tataagagatcgagaacccgagaatgcaataatcctgccccccaacgaggagggaaacgc tgtgagggggagaagcgacaagaggaagactgcacattttcaatcatggaaaacaatgga caaccatgtatcaatgatgacgaagaaatgaaagaggtcgatcttcctgagatagaagca gattccgggtgtcctcagccagttcctccagaaaatggatttatccggaatgaaaagcaa ctatacttggttggagaagatgttgaaatttcatgccttactggctttgaaactgttgga taccagtacttcagatgcttaccagacgggacctggagacaaggggatgtggaatgccaa cggacggagtgcatcaagccagttgtgcaggaagtcctgacaattacaccatttcagaga ttgtatagaattggtgaatccattgagctaacttgccccaaaggctttgttgttgctggg ccatcaaggtacacatgccaggggaattcctggacaccacccatttcaaactctctcacc tgtgaaaaagatactctaacaaaattaaaaggccattgtcagctgggacagaaacaatca ggatctgaatgcatttgtatgtctccagaagaagactgtagccatcattcagaagatctc tgtgtgtttgacacagactccaacgattactttacttcacccgcttgtaagtttttggct gagaaatgtttaaataatcagcaactccattttctacatattggttcctgccaagacggc cgccagttagaatggggtcttgaaaggacaagactttcatccaacagcacaaagaaagaa tcctgtggctatgacacctgctatgactgggaaaaatgttcagcctccacttccaaatgt gtctgcctattgcccccacagtgcttcaagggtggaaaccaactctactgtgtcaaaatg ggatcatcaacaagtgagaaaacattgaacatctgtgaagtgggaactataagatgtgca aacaggaagatggaaatactgcatcctggaaagtgtttggcctag

Homo sapiens (human): 730 Help Entry 730               CDS       T01001                                  Symbol C7 Name (RefSeq) complement C7   KO K03996   complement component 7 Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     730 (C7)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     730 (C7)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     730 (C7)   09163 Immune disease    05322 Systemic lupus erythematosus     730 (C7)   09164 Neurodegenerative disease    05020 Prion disease     730 (C7) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF Kazal_C7 Kazal_3 Sushi C7_FIM2_N TSP_1 Ldl_recept_a EGF_C8A_B_C6 Motif Other DBs NCBI-GeneID:  730 NCBI-ProteinID:  NP_000578 OMIM:  217070 HGNC:  1346 Ensembl:  ENSG00000112936 UniProt:  P10643 Q05CI3 Structure PDBPDBj LinkDB All DBs Position 5:40909497..40984643 Genome browser AA seq 843 aa AA seqDB search MKVISLFILVGFIGEFQSFSSASSPVNCQWDFYAPWSECNGCTKTQTRRRSVAVYGQYGG QPCVGNAFETQSCEPTRGCPTEEGCGERFRCFSGQCISKSLVCNGDSDCDEDSADEDRCE DSERRPSCDIDKPPPNIELTGNGYNELTGQFRNRVINTKSFGGQCRKVFSGDGKDFYRLS GNVLSYTFQVKINNDFNYEFYNSTWSYVKHTSTEHTSSSRKRSFFRSSSSSSRSYTSHTN EIHKGKSYQLLVVENTVEVAQFINNNPEFLQLAEPFWKELSHLPSLYDYSAYRRLIDQYG THYLQSGSLGGEYRVLFYVDSEKLKQNDFNSVEEKKCKSSGWHFVVKFSSHGCKELENAL KAASGTQNNVLRGEPFIRGGGAGFISGLSYLELDNPAGNKRRYSAWAESVTNLPQVIKQK LTPLYELVKEVPCASVKKLYLKWALEEYLDEFDPCHCRPCQNGGLATVEGTHCLCHCKPY TFGAACEQGVLVGNQAGGVDGGWSCWSSWSPCVQGKKTRSRECNNPPPSGGGRSCVGETT ESTQCEDEELEHLRLLEPHCFPLSLVPTEFCPSPPALKDGFVQDEGTMFPVGKNVVYTCN EGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCS GGMSLEGPSAFLCGSSLKWSPEMKNARCVQKENPLTQAVPKCQRWEKLQNSRCVCKMPYE CGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWG KCDAESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAA ETQ NT seq 2532 nt NT seq  +upstreamnt  +downstreamnt atgaaggtgataagcttattcattttggtgggatttataggagagttccaaagtttttca agtgcctcctctccagtcaactgccagtgggacttctatgccccttggtcagaatgcaat ggctgtaccaagactcagactcgcaggcggtcagttgctgtgtatgggcagtatggaggc cagccttgtgttggaaatgcttttgaaacacagtcctgtgaacctacaagaggatgtcca acagaggagggatgtggagagcgtttcaggtgcttttcaggtcagtgcatcagcaaatca ttggtttgcaatggggattctgactgtgatgaagacagtgctgatgaagacagatgtgag gactcagaaaggagaccttcctgtgatatcgataaacctcctcctaacatagaacttact ggaaatggttacaatgaactcactggccagtttaggaacagagtcatcaataccaaaagt tttggtggtcaatgtagaaaggtgtttagtggggatggaaaagatttctacaggctgagt ggaaatgtcctgtcctatacattccaggtgaaaataaataatgattttaattatgaattt tacaatagtacttggtcttatgtaaaacatacgtcgacagaacacacatcatctagtcgg aagcgctccttttttagatcttcatcatcttcttcacgcagttatacttcacataccaat gaaatccataaaggaaagagttaccaactgctggttgttgagaacactgttgaagtggct cagttcattaataacaatccagaatttttacaacttgctgagccattctggaaggagctt tcccacctcccctctctgtatgactacagtgcctaccgaagattaatcgaccagtacggg acacattatctgcaatctgggtcgttaggaggagaatacagagttctattttatgtggac tcagaaaaattaaaacaaaatgattttaattcagtcgaagaaaagaaatgtaaatcctca ggttggcattttgtcgttaaattttcaagtcatggatgcaaggaactggaaaacgcttta aaagctgcttcaggaacccagaacaatgtattgcgaggagaaccgttcatcagaggggga ggtgcaggcttcatatctggccttagttacctagagctggacaatcctgctggaaacaaa aggcgatattctgcctgggcagaatctgtgactaatcttcctcaagtcataaaacaaaag ctgacacctttatatgagctggtaaaggaagtaccttgtgcctctgtgaaaaaactatac ctgaaatgggctcttgaagagtatctggatgaatttgacccctgtcattgccggccttgt caaaatggtggtttggctactgttgaggggacccattgtctgtgccattgcaaaccgtac acatttggtgcggcgtgtgagcaaggagtcctcgtagggaatcaagcaggaggggttgat ggaggttggagttgctggtcctcttggagcccctgtgtccaagggaagaaaacaagaagc cgtgaatgcaataacccacctcccagtgggggtgggagatcctgcgttggagaaacgaca gaaagcacacaatgcgaagatgaggagctggagcacttgaggttgcttgaaccacattgc tttcctttgtctttggttccaacagaattctgtccatcacctcctgccttgaaagatgga tttgttcaagatgaaggtacaatgtttcctgtggggaaaaatgtagtgtacacttgcaat gaaggatactctcttattggaaacccagtggccagatgtggagaagatttacggtggctt gttggggaaatgcattgtcagaaaattgcctgtgttctacctgtactgatggatggcata cagagtcacccccaaaaacctttctacacagttggtgagaaggtgactgtttcctgttca ggtggcatgtccttagaaggtccttcagcatttctctgtggctccagccttaagtggagt cctgagatgaagaatgcccgctgtgtacaaaaagaaaatccgttaacacaggcagtgcct aaatgtcagcgctgggagaaactgcagaattcaagatgtgtttgtaaaatgccctacgaa tgtggaccttccttggatgtatgtgctcaagatgagagaagcaaaaggatactgcctctg acagtttgcaagatgcatgttctccactgtcagggtagaaattacacccttactggtagg gacagctgtactctgcctgcctcagctgagaaagcttgtggtgcctgcccactgtgggga aaatgtgatgctgagagcagcaaatgtgtctgccgagaagcatcggagtgcgaggaagaa gggtttagcatttgtgtggaagtgaacggcaaggagcagacgatgtctgagtgtgaggcg ggcgctctgagatgcagagggcagagcatctctgtcaccagcataaggccttgtgctgcg gaaacccagtag

Homo sapiens (human): 731 Help Entry 731               CDS       T01001                                  Symbol C8A Name (RefSeq) complement C8 alpha chain   KO K03997   complement component 8 subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05146   Amoebiasis hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     731 (C8A)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     731 (C8A)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     731 (C8A)   09174 Infectious disease: parasitic    05146 Amoebiasis     731 (C8A)   09163 Immune disease    05322 Systemic lupus erythematosus     731 (C8A)   09164 Neurodegenerative disease    05020 Prion disease     731 (C8A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF EGF_C8A_B_C6 Ldl_recept_a TSP_1 TSP1_spondin Motif Other DBs NCBI-GeneID:  731 NCBI-ProteinID:  NP_000553 OMIM:  120950 HGNC:  1352 Ensembl:  ENSG00000157131 UniProt:  P07357 Structure PDBPDBj LinkDB All DBs Position 1:56854797..56918223 Genome browser AA seq 584 aa AA seqDB search MFAVVFFILSLMTCQPGVTAQEKVNQRVRRAATPAAVTCQLSNWSEWTDCFPCQDKKYRH RSLLQPNKFGGTICSGDIWDQASCSSSTTCVRQAQCGQDFQCKETGRCLKRHLVCNGDQD CLDGSDEDDCEDVRAIDEDCSQYEPIPGSQKAALGYNILTQEDAQSVYDASYYGGQCETV YNGEWRELRYDSTCERLYYGDDEKYFRKPYNFLKYHFEALADTGISSEFYDNANDLLSKV KKDKSDSFGVTIGIGPAGSPLLVGVGVSHSQDTSFLNELNKYNEKKFIFTRIFTKVQTAH FKMRKDDIMLDEGMLQSLMELPDQYNYGMYAKFINDYGTHYITSGSMGGIYEYILVIDKA KMESLGITSRDITTCFGGSLGIQYEDKINVGGGLSGDHCKKFGGGKTERARKAMAVEDII SRVRGGSSGWSGGLAQNRSTITYRSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEAKR QNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCRCQCRLGSLGAACEQTQTEGAKADG SWSCWSSWSVCRAGIQERRRECDNPAPQNGGASCPGRKVQTQAC NT seq 1755 nt NT seq  +upstreamnt  +downstreamnt atgtttgctgttgttttcttcatcttgtctttgatgacttgtcagcctggggtaactgca caggagaaggtgaaccagagagtaagacgggcagctacacccgcagcagttacctgccag ctgagcaactggtcagagtggacagattgctttccgtgccaggacaaaaagtaccgacac cggagcctcttgcagccaaacaagtttgggggaaccatctgcagtggtgacatctgggat caagccagctgctccagttctacaacttgtgtaaggcaagcacagtgtggacaggatttc cagtgtaaggagacaggtcgctgcctgaaacgccaccttgtgtgtaatggagaccaggac tgccttgatggctctgatgaggacgactgtgaagatgtcagggccattgacgaagactgc agccagtatgaaccaattccaggatcacagaaggcagccttggggtacaatatcctgacc caggaagatgctcagagtgtgtacgatgccagttattatgggggccagtgtgagacggta tacaatggggaatggagggagcttcgatatgactccacctgtgaacgtctctactatgga gatgatgagaaatactttcggaaaccctacaactttctgaagtaccactttgaagccctg gcagatactggaatctcctcagagttttatgataatgcaaatgaccttctttccaaagtt aaaaaagacaagtctgactcatttggagtgaccatcggcataggcccagccggcagccct ttattggtgggtgtaggtgtatcccactcacaagacacttcattcttgaacgaattaaac aagtataatgagaagaaattcattttcacaagaatcttcacaaaggtgcagactgcacat tttaagatgaggaaggatgacattatgctggatgaaggaatgctgcagtcattaatggag cttccagatcagtacaattatggcatgtatgccaagttcatcaatgactatggcacccat tacatcacatctggatccatgggtggcatttatgaatatatcctggtgattgacaaagca aaaatggaatcccttggtattaccagcagagatatcacgacatgttttggaggctccttg ggcattcaatatgaagacaaaataaatgttggtggaggtttatcaggagaccattgtaaa aaatttggaggtggcaaaactgaaagggccaggaaggccatggctgtggaagacattatt tctcgggtgcgaggtggcagttctggctggagcggtggcttggcacagaacaggagcacc attacataccgttcctgggggaggtcattaaagtataatcctgttgttatcgattttgag atgcagcctatccacgaggtgctgcggcacacaagcctggggcctctggaggccaagcgc cagaacctgcgccgcgccttggaccagtatctgatggaattcaatgcctgccgatgtggg ccttgcttcaacaatggggtgcccatcctcgagggcaccagctgcaggtgccagtgccgc ctgggtagcttgggtgctgcctgtgagcaaacacagacagaaggagccaaagcagatggg agctggagttgctggagctcctggtctgtatgcagagcaggcatccaggaaaggagaaga gagtgtgacaatccagcacctcagaatggaggggcctcgtgtccagggcggaaagtacag acgcaggcttgctga

Homo sapiens (human): 732 Help Entry 732               CDS       T01001                                  Symbol C8B, C82 Name (RefSeq) complement C8 beta chain   KO K03998   complement component 8 subunit beta Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05146   Amoebiasis hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     732 (C8B)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     732 (C8B)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     732 (C8B)   09174 Infectious disease: parasitic    05146 Amoebiasis     732 (C8B)   09163 Immune disease    05322 Systemic lupus erythematosus     732 (C8B)   09164 Neurodegenerative disease    05020 Prion disease     732 (C8B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF EGF_C8A_B_C6 Ldl_recept_a TSP_1 TSP1_spondin Motif Other DBs NCBI-GeneID:  732 NCBI-ProteinID:  NP_000057 OMIM:  120960 HGNC:  1353 Ensembl:  ENSG00000021852 UniProt:  P07358 A0A8Q3WL56 Structure PDBPDBj LinkDB All DBs Position 1:complement(56929207..56966015) Genome browser AA seq 591 aa AA seqDB search MKNSRTWAWRAPVELFLLCAALGCLSLPGSRGERPHSFGSNAVNKSFAKSRQMRSVDVTL MPIDCELSSWSSWTTCDPCQKKRYRYAYLLQPSQFHGEPCNFSDKEVEDCVTNRPCGSQV RCEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCRRIYKKCQHEMDQYWGIGSLASGIN LFTNSFEGPVLDHRYYAGGCSPHYILNTRFRKPYNVESYTPQTQGKYEFILKEYESYSDF ERNVTEKMASKSGFSFGFKIPGIFELGISSQSDRGKHYIRRTKRFSHTKSVFLHARSDLE VAHYKLKPRSLMLHYEFLQRVKRLPLEYSYGEYRDLFRDFGTHYITEAVLGGIYEYTLVM NKEAMERGDYTLNNVHACAKNDFKIGGAIEEVYVSLGVSVGKCRGILNEIKDRNKRDTMV EDLVVLVRGGASEHITTLAYQELPTADLMQEWGDAVQYNPAIIKVKVEPLYELVTATDFA YSSTVRQNMKQALEEFQKEVSSCHCAPCQGNGVPVLKGSRCDCICPVGSQGLACEVSYRK NTPIDGKWNCWSNWSSCSGRRKTRQRQCNNPPPQNGGSPCSGPASETLDCS NT seq 1776 nt NT seq  +upstreamnt  +downstreamnt atgaagaattccaggacatgggcttggagggcgccggtggagctatttcttctctgtgct gccctgggctgtctcagtttgcctggctccagaggtgaaaggccacattcctttgggtca aatgcagtcaacaagagctttgctaagagcagacagatgcggagtgtggatgttaccctg atgcccattgattgtgagctgtctagttggtcctcttggaccacatgtgacccctgtcag aagaaaaggtacaggtatgcctacttgctccagccctctcagttccatggggaaccgtgc aacttctctgacaaggaagtcgaagactgtgttaccaacagaccatgcggaagtcaagtg cgatgtgaaggctttgtgtgtgcacagacaggaaggtgtgtaaaccgcagacttctttgc aatggggacaatgactgtggagaccagtcagatgaagcaaactgtagaaggatttataaa aaatgtcagcatgaaatggaccaatactggggaattggcagtctggccagtgggataaat ttgttcacaaacagttttgagggcccagttcttgatcacaggtattatgcaggtggatgc tccccgcattacatcctgaacacgaggtttaggaagccctacaatgtggaaagctacacg ccacagacccaaggcaaatacgaattcatattaaaagagtatgaatcatactcagatttt gaacgcaatgtcacagagaaaatggcaagcaagtctggtttcagttttggttttaaaata cctggaatatttgaacttggcatcagtagtcaaagtgatcgaggcaaacactatattagg agaaccaaacgattctctcatactaaaagcgtatttctgcatgcacgctctgaccttgaa gtagcacattacaagctgaaacccagaagcctcatgctccattacgagttccttcagaga gttaagcggctgcccctggagtacagctacggggaatacagagatctcttccgtgatttt gggacccactacatcacagaggctgtgcttgggggcatttatgaatacaccctcgttatg aacaaagaggccatggagagaggagattatactcttaacaacgtccatgcctgtgccaaa aatgattttaaaattggtggtgccattgaagaggtctacgtcagtctgggtgtgtctgta ggcaaatgcagaggtattctgaatgaaataaaagacagaaacaagagggacaccatggtg gaggacttggtggtcctggtacgaggaggggcaagtgagcacatcaccaccctggcatac caggagctgccgacggcggacctgatgcaggagtggggagacgctgtgcagtacaaccca gccatcatcaaagttaaggtggagcctctgtatgaactagtgacagccacagattttgcc tattccagcacagtgaggcagaacatgaagcaggcactggaggagttccagaaggaagtt agttcctgccactgtgctccctgccaaggaaatggagtccctgtcctgaaaggatcacgc tgtgactgcatctgtcctgttggatcccaaggcctagcctgtgaggtctcctatcggaag aatacccccattgatgggaagtggaattgctggtcaaattggtcttcatgctctggaaga cgtaagacaagacaaaggcagtgtaacaatccacctcctcaaaatgggggtagcccctgt tcaggccctgcttcagaaacacttgactgctcctag

Homo sapiens (human): 733 Help Entry 733               CDS       T01001                                  Symbol C8G, C8C Name (RefSeq) complement C8 gamma chain   KO K03999   complement component 8 subunit gamma Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05146   Amoebiasis hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     733 (C8G)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     733 (C8G)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     733 (C8G)   09174 Infectious disease: parasitic    05146 Amoebiasis     733 (C8G)   09163 Immune disease    05322 Systemic lupus erythematosus     733 (C8G)   09164 Neurodegenerative disease    05020 Prion disease     733 (C8G) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipocalin Motif Other DBs NCBI-GeneID:  733 NCBI-ProteinID:  NP_000597 OMIM:  120930 HGNC:  1354 Ensembl:  ENSG00000176919 UniProt:  P07360 Structure PDBPDBj LinkDB All DBs Position 9:136945243..136946975 Genome browser AA seq 202 aa AA seqDB search MLPPGTATLLTLLLAAGSLGQKPQRPRRPASPISTIQPKANFDAQQFAGTWLLVAVGSAC RFLQEQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARDAR GAVHVVVAETDYQSFAVLYLERAGQLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIF YFPKYGFCEAADQFHVLDEVRR NT seq 609 nt NT seq  +upstreamnt  +downstreamnt atgctgccccctgggactgcgaccctcttgactctgctcctggcagctggctcgctgggc cagaagcctcagaggccacgccggcccgcatcccccatcagcaccatccagcccaaggcc aattttgatgctcagcagtttgcagggacctggctccttgtggctgtgggctccgcttgc cgtttcctgcaggagcagggccaccgggccgaggccaccacactgcatgtggctccccag ggcacagccatggctgtcagtaccttccgaaagctggatgggatctgctggcaggtgcgc cagctctatggagacacaggggtcctcggccgcttcctgcttcaagcccgagacgcccga ggggctgtgcacgtggttgtcgctgagaccgactaccagagtttcgctgtcctgtacctg gagcgggcggggcagctgtcagtgaagctctacgcccgctcgctccctgtgagcgactcg gtcctgagtgggtttgagcagcgggtccaggaggcccacctgactgaggaccagatcttc tacttccccaagtacggcttctgcgaggctgcagaccagttccacgtcctggacgaagtg aggaggtga

Homo sapiens (human): 735 Help Entry 735               CDS       T01001                                  Symbol C9, ARMD15, C9D Name (RefSeq) complement C9   KO K04000   complement component 9 Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05146   Amoebiasis hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects H00821   Age-related macular degeneration Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     735 (C9)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     735 (C9)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     735 (C9)   09174 Infectious disease: parasitic    05146 Amoebiasis     735 (C9)   09163 Immune disease    05322 Systemic lupus erythematosus     735 (C9)   09164 Neurodegenerative disease    05020 Prion disease     735 (C9) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF Ldl_recept_a TSP1_spondin TSP_1 EGF_C8A_B_C6 eIF-5_eIF-2B Motif Other DBs NCBI-GeneID:  735 NCBI-ProteinID:  NP_001728 OMIM:  120940 HGNC:  1358 Ensembl:  ENSG00000113600 UniProt:  P02748 Structure PDBPDBj LinkDB All DBs Position 5:complement(39284140..39364495) Genome browser AA seq 559 aa AA seqDB search MSACRSFAVAICILEISILTAQYTTSYDPELTESSGSASHIDCRMSPWSEWSQCDPCLRQ MFRSRSIEVFGQFNGKRCTDAVGDRRQCVPTEPCEDAEDDCGNDFQCSTGRCIKMRLRCN GDNDCGDFSDEDDCESEPRPPCRDRVVEESELARTAGYGINILGMDPLSTPFDNEFYNGL CNRDRDGNTLTYYRRPWNVASLIYETKGEKNFRTEHYEEQIEAFKSIIQEKTSNFNAAIS LKFTPTETNKAEQCCEETASSISLHGKGSFRFSYSKNETYQLFLSYSSKKEKMFLHVKGE IHLGRFVMRNRDVVLTTTFVDDIKALPTTYEKGEYFAFLETYGTHYSSSGSLGGLYELIY VLDKASMKRKGVELKDIKRCLGYHLDVSLAFSEISVGAEFNKDDCVKRGEGRAVNITSEN LIDDVVSLIRGGTRKYAFELKEKLLRGTVIDVTDFVNWASSINDAPVLISQKLSPIYNLV PVKMKNAHLKKQNLERAIEDYINEFSVRKCHTCQNGGTVILMDGKCLCACPFKFEGIACE ISKQKISEGLPALEFPNEK NT seq 1680 nt NT seq  +upstreamnt  +downstreamnt atgtcagcctgccggagctttgcagttgcaatctgcattttagaaataagcatcctcaca gcacagtacacgaccagttatgacccagagctaacagaaagcagtggctctgcatcacac atagactgcagaatgagcccctggagtgaatggtcacaatgcgatccttgtctcagacaa atgtttcgttcaagaagcattgaggtctttggacaatttaatgggaaaagatgcaccgac gctgtgggagacagacgacagtgtgtgcccacagagccctgtgaggatgctgaggatgac tgcggaaatgactttcaatgcagtacaggcagatgcataaagatgcgacttcggtgtaat ggtgacaatgactgcggagacttttcagatgaggatgattgtgaaagtgagccccgtccc ccctgcagagacagagtggtagaagagtctgagctggcacgaacagcaggctatgggatc aacattttagggatggatcccctaagcacaccttttgacaatgagttctacaatggactc tgtaaccgggatcgggatggaaacactctgacatactaccgaagaccttggaacgtggct tctttgatctatgaaaccaaaggcgagaaaaatttcagaaccgaacattacgaagaacaa attgaagcatttaaaagtatcatccaagagaagacatcaaattttaatgcagctatatct ctaaaatttacacccactgaaacaaataaagctgaacaatgttgtgaggaaacagcctcc tcaatttctttacatggcaagggtagttttcggttttcatattccaaaaatgaaacttac caactatttttgtcatattcttcaaagaaggaaaaaatgtttctgcatgtgaaaggagaa attcatctgggaagatttgtaatgagaaatcgcgatgttgtgctcacaacaacttttgtg gatgatataaaagctttgccaactacctatgaaaagggagaatattttgcctttttggaa acctatggaactcactacagtagctctgggtctctaggaggactctatgaactaatatat gttttggataaagcttccatgaagcggaaaggtgttgaactaaaagacataaagagatgc cttgggtatcatctggatgtatctctggctttctctgaaatctctgttggagctgaattt aataaagatgattgtgtaaagaggggagagggtagagctgtaaacatcaccagtgaaaac ctcatagatgatgttgtttcactcataagaggtggaaccagaaaatatgcatttgaactg aaagaaaagcttctccgaggaaccgtgattgatgtgactgactttgtcaactgggcctct tccataaatgatgctcctgttctcattagtcaaaaactgtctcctatatataatctggtt ccagtgaaaatgaaaaatgcacacctaaagaaacaaaacttggaaagagccattgaagac tatatcaatgaatttagtgtaagaaaatgccacacatgccaaaatggaggtacagtgatt ctaatggatggaaagtgtttgtgtgcctgcccattcaaatttgagggaattgcctgtgaa atcagtaaacaaaaaatttctgaaggattgccagccctagagttccccaatgaaaaatag

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