KEGG ORTHOLOGY: K08047

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08047  ADCY7; adenylate cyclase 7
09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04371 Apelin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04020 Calcium signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04072 Phospholipase D signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04024 cAMP signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04022 cGMP-PKG signaling pathway
    K08047  ADCY7; adenylate cyclase 7
09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08047  ADCY7; adenylate cyclase 7
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08047  ADCY7; adenylate cyclase 7
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08047  ADCY7; adenylate cyclase 7
   04062 Chemokine signaling pathway
    K08047  ADCY7; adenylate cyclase 7
  09152 Endocrine system
   04911 Insulin secretion
    K08047  ADCY7; adenylate cyclase 7
   04923 Regulation of lipolysis in adipocytes
    K08047  ADCY7; adenylate cyclase 7
   04912 GnRH signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04913 Ovarian steroidogenesis
    K08047  ADCY7; adenylate cyclase 7
   04915 Estrogen signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04914 Progesterone-mediated oocyte maturation
    K08047  ADCY7; adenylate cyclase 7
   04921 Oxytocin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04926 Relaxin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04935 Growth hormone synthesis, secretion and action
    K08047  ADCY7; adenylate cyclase 7
   04918 Thyroid hormone synthesis
    K08047  ADCY7; adenylate cyclase 7
   04928 Parathyroid hormone synthesis, secretion and action
    K08047  ADCY7; adenylate cyclase 7
   04916 Melanogenesis
    K08047  ADCY7; adenylate cyclase 7
   04925 Aldosterone synthesis and secretion
    K08047  ADCY7; adenylate cyclase 7
   04927 Cortisol synthesis and secretion
    K08047  ADCY7; adenylate cyclase 7
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08047  ADCY7; adenylate cyclase 7
   04270 Vascular smooth muscle contraction
    K08047  ADCY7; adenylate cyclase 7
  09154 Digestive system
   04970 Salivary secretion
    K08047  ADCY7; adenylate cyclase 7
   04971 Gastric acid secretion
    K08047  ADCY7; adenylate cyclase 7
   04972 Pancreatic secretion
    K08047  ADCY7; adenylate cyclase 7
   04976 Bile secretion
    K08047  ADCY7; adenylate cyclase 7
  09156 Nervous system
   04724 Glutamatergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04727 GABAergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04725 Cholinergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04723 Retrograde endocannabinoid signaling
    K08047  ADCY7; adenylate cyclase 7
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08047  ADCY7; adenylate cyclase 7
  09149 Aging
   04211 Longevity regulating pathway
    K08047  ADCY7; adenylate cyclase 7
   04213 Longevity regulating pathway - multiple species
    K08047  ADCY7; adenylate cyclase 7
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08047  ADCY7; adenylate cyclase 7
   04714 Thermogenesis
    K08047  ADCY7; adenylate cyclase 7
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08047  ADCY7; adenylate cyclase 7
  09165 Substance dependence
   05032 Morphine addiction
    K08047  ADCY7; adenylate cyclase 7
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08047  ADCY7; adenylate cyclase 7
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08047  ADCY7; adenylate cyclase 7
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08047  ADCY7; adenylate cyclase 7
   05163 Human cytomegalovirus infection
    K08047  ADCY7; adenylate cyclase 7
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08047  ADCY7; adenylate cyclase 7
Enzymes [BR:ko01000]
4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08047  ADCY7; adenylate cyclase 7

Other DBs

RN:	R00089 R00434

GO:

0004016

Genes

HSA:	113(ADCY7)

PTR:	473278(ADCY7)

PPS:	100984225(ADCY7)

GGO:	101126268(ADCY7)

PON:	100436577(ADCY7)

NLE:	100587036(ADCY7)

MCC:	694730(ADCY7)

MCF:	102125718(ADCY7)

CSAB:

103232667(ADCY7)

RRO:	104672569(ADCY7)

RBB:	108522948(ADCY7)

CJC:	100404620(ADCY7)

SBQ:	101032672(ADCY7)

MMU:	11513(Adcy7)

MCAL:

110299719(Adcy7)

MPAH:

110337453(Adcy7)

RNO:	84420(Adcy7)

MUN:	110560723(Adcy7)

CGE:	100756132(Adcy7)

NGI:	103730120(Adcy7)

HGL:	101712483(Adcy7)

CCAN:

109698373(Adcy7)

OCU:	100357357(ADCY7)

TUP:	102496578(ADCY7)

CFA:	487289(ADCY7)

VVP:	112929565(ADCY7)

AML:	100466965(ADCY7)

UMR:	103673916(ADCY7)

UAH:	113252223(ADCY7)

ORO:	101377421(ADCY7)

ELK:

111157326

FCA:	101094148(ADCY7)

PTG:	102972917(ADCY7)

PPAD:

109270953(ADCY7)

AJU:	106985835(ADCY7)

BTA:	281603(ADCY7)

BOM:	102266966(ADCY7)

BIU:	109572478(ADCY7)

BBUB:

102410456(ADCY7)

CHX:	102185858(ADCY7)

OAS:	101112667(ADCY7)

SSC:	100620994(ADCY7)

CFR:	102524614(ADCY7)

CDK:	105097528(ADCY7)

BACU:

102997912(ADCY7)

LVE:	103078677(ADCY7)

OOR:	101273592(ADCY7)

DLE:	111164991(ADCY7)

PCAD:

102985075(ADCY7)

ECB:	100058891(ADCY7)

EPZ:	103556685(ADCY7)

EAI:	106824126(ADCY7)

MYB:	102253549(ADCY7)

MYD:	102764043(ADCY7)

MNA:	107531029(ADCY7)

HAI:	109383261(ADCY7)

DRO:	112296774(ADCY7)

PALE:

102881535(ADCY7)

RAY:	107512248(ADCY7)

MJV:	108407296(ADCY7)

LAV:	100653771(ADCY7)

TMU:

101341715

MDO:	100013823(ADCY7)

SHR:	100929278(ADCY7)

PCW:	110207473(ADCY7)

OAA:	100076221(ADCY7)

GGA:	415732(ADCY7)

MGP:

100548914

CJO:	107319017(ADCY7)

NMEL:

110404374(ADCY7)

APLA:

101794076(ADCY7)

ACYG:

106039584(ADCY7)

TGU:	100225700(ADCY7)

LSR:	110473537(ADCY7)

SCAN:

103816806(ADCY7)

GFR:	102043194(ADCY7)

FAB:	101816007(ADCY7)

PHI:	102106688(ADCY7)

PMAJ:

107209841(ADCY7)

CCAE:

111934618(ADCY7)

CCW:	104687454(ADCY7)

ETL:	114055552(ADCY7)

FPG:	101914615(ADCY7)

FCH:	102052224(ADCY7)

CLV:	102090470(ADCY7)

EGZ:	104125176(ADCY7)

NNI:	104011289(ADCY7)

ACUN:

113484440(ADCY7)

PADL:

103913801(ADCY7)

AAM:	106483289(ADCY7)

ASN:	102368976(ADCY7)

AMJ:	102566330(ADCY7)

PSS:	102449192(ADCY7)

CMY:	102946407(ADCY7)

CPIC:

101938536(ADCY7)

ACS:	100558751(adcy7)

PVT:	110086573(ADCY7)

PBI:	103060035(ADCY7)

PMUR:

107290046(ADCY7)

TSR:	106554339(ADCY7)

PMUA:

114602227(ADCY7)

GJA:	107117185(ADCY7)

XLA:	399055(adcy7.L)

XTR:	100127741(adcy7)

NPR:	108794932(ADCY7)

DRE:	568726(adcy7)

SRX:	107742778 107750233

SANH:

107657123 107696709

SGH:	107551487 107554606

CCAR:

109080760 109091999

IPU:	108259218(adcy7)

PHYP:

113540899(adcy7)

AMEX:

103025161(adcy7)

EEE:

113581231

TRU:	101066272(adcy7)

LCO:	104940647(adcy7)

MZE:	101480238(adcy7)

ONL:	100703488(adcy7)

OLA:	101164967(adcy7)

XMA:	102223009(adcy7)

XCO:	114142861(adcy7)

PRET:

103462645(adcy7)

CVG:	107088499(adcy7)

NFU:	107381237(adcy7)

KMR:	108243337(adcy7)

ALIM:

106527041

AOCE:

111572244(adcy7)

CSEM:

103398552

POV:	109625125(adcy7)

LCF:	108876970(adcy7)

SDU:	111217971(adcy7)

SLAL:

111672304(adcy7)

HCQ:	109513976(adcy7)

BPEC:

110175272(adcy7)

MALB:

109955816(adcy7)

SASA:

106562384 106587576

OTW:	112249333 112249354

SALP:

111974474

ELS:	105025700(adcy7)

SFM:

108932972

PKI:	111832687 111848207

LCM:	102351065(ADCY7)

CMK:	103176081(adcy7)

RTP:

109923754

» show all

Reference

PMID:7961850

Authors

Watson PA, Krupinski J, Kempinski AM, Frankenfield CD

Title

Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells.

Journal

J Biol Chem 269:28893-8 (1994)

Sequence

[hsa:113]

Reference

PMID:22264442

Authors

Joeyen-Waldorf J, Nikolova YS, Edgar N, Walsh C, Kota R, Lewis DA, Ferrell R, Manuck SB, Hariri AR, Sibille E

Title

Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry.

Journal

Biol Psychiatry 71:627-32 (2012)
DOI:10.1016/j.biopsych.2011.11.029

LinkDB

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