KEGG ORTHOLOGY: K04400

ORTHOLOGY: K04400

Entry

K04400                      KO

Symbol

CASP10

Name

caspase 10 [EC:3.4.22.63]

Pathway

map04210

Apoptosis

map04622

RIG-I-like receptor signaling pathway

map04668

TNF signaling pathway

map05152

Tuberculosis

map05161

Hepatitis B

Disease

H00108

Autoimmune lymphoproliferative syndromes

H02418

Non-Hodgkin lymphoma

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    K04400  CASP10; caspase 10
09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04400  CASP10; caspase 10
09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    K04400  CASP10; caspase 10
09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    K04400  CASP10; caspase 10
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K04400  CASP10; caspase 10
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K04400  CASP10; caspase 10
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.63  caspase-10
     K04400  CASP10; caspase 10
Peptidases and inhibitors [BR:ko01002]
Cysteine peptidases
  Family C14: caspase family
   K04400  CASP10; caspase 10

Other DBs

GO:

0097199

Genes

HSA:	843(CASP10)

PTR:	459873(CASP10)

PPS:	100972863(CASP10)

GGO:	101131419(CASP10)

PON:	100174433(CASP10)

NLE:	100585413(CASP10)

HMH:	116810460(CASP10)

MCC:	701295(CASP10)

MCF:	102144792(CASP10)

MTHB:

126932109

MNI:	105468106(CASP10)

CSAB:

103217635(CASP10)

CATY:

105580202(CASP10)

PANU:

101011831(CASP10)

TGE:	112636361(CASP10)

MLEU:

105535423(CASP10)

RRO:	104671862(CASP10)

RBB:	108532107(CASP10)

TFN:	117095222(CASP10)

PTEH:

111547163(CASP10)

CANG:

105517471(CASP10)

CJC:	100394139(CASP10)

SBQ:	101028043(CASP10)

CIMI:

108315752(CASP10)

CSYR:

103273364(CASP10)

MMUR:

105856963(CASP10)

LCAT:

123643896(CASP10)

PCOQ:

105819115(CASP10)

OGA:	100965785(CASP10)

HGL:	101712620(Casp10)

CPOC:

100717714(Casp10)

NCAR:

124980755

MMMA:

107138606(Casp10)

OCU:	100101580(CASP10)

OPI:	101520873(CASP10)

TUP:	102496563(CASP10)

GVR:	103597793(CASP10)

CFA:	488472(CASP10)

CLUD:

112656355(CASP10)

VVP:	112922875(CASP10)

VLG:	121480767(CASP10)

NPO:	129522918(CASP10)

AML:	100475128(CASP10)

UMR:	103659739(CASP10)

UAH:	113250594(CASP10)

UAR:	123798198(CASP10)

ELK:

111141157

LLV:

125094997

MPUF:

101685031(CASP10)

MNP:	132013448(CASP10)

MLK:	131827576(CASP10)

NVS:	122902189(CASP10)

ORO:	101366538(CASP10)

EJU:	114223391(CASP10)

ZCA:	113920561(CASP10)

MLX:	118012154(CASP10)

NSU:	110592146(CASP10)

FCA:	101085995(CASP10)

PYU:	121030907(CASP10)

PCOO:

112872042(CASP10)

PBG:	122481640(CASP10)

PVIV:

125172183(CASP10)

LRUF:

124515024

PTG:	102962753(CASP10)

PPAD:

109260756(CASP10)

PUC:

125911770

AJU:

106987987

HHV:	120220687(CASP10)

BTA:

100848685

BBUB:

102394793

OAS:	101103049(CASP10)

BTAX:

128060900(CASP10)

ODA:

120854625

MBEZ:

129538551(CASP10)

SSC:	100154896(CASP10)

CFR:	102514092(CASP10)

CBAI:

105082301(CASP10)

CDK:	105099180(CASP10)

VPC:	102540480(CASP10)

BACU:

103001347(CASP10)

BMUS:

118897930(CASP10)

LVE:	103076785(CASP10)

OOR:	101282021(CASP10)

DLE:	111171725(CASP10)

PCAD:

102989304(CASP10)

PSIU:

116756541(CASP10)

NASI:

112407867(CASP10)

ECB:	100068201(CASP10)

EPZ:	103566002(CASP10)

EAI:	106823486(CASP10)

MYB:	102253536(CASP10)

MYD:	102763065(CASP10)

MMYO:

118661389(CASP10)

MLF:	102434278 102439064(CASP10)

PKL:	118708994(CASP10)

EFUS:

103290617(CASP10)

MNA:	107533942(CASP10)

DRO:	112308028(CASP10)

SHON:

118985243(CASP10)

AJM:	119065494(CASP10)

PDIC:

114494329(CASP10)

PHAS:

123824433(CASP10)

MMF:	118625231(CASP10)

PPAM:

129080427(CASP10)

HAI:	109379185(CASP10)

RFQ:	117026299(CASP10)

PALE:

102877929(CASP10)

PGIG:

120587527(CASP10)

PVP:	105298128(CASP10)

RAY:	107503159(CASP10)

MJV:	108404750(CASP8)

TOD:	119256100(CASP10) 119260153

SETR:

126008676

LAV:

100663859

TMU:

101341837

ETF:	101664540(CASP10)

DNM:	101433860(CASP10)

MDO:	100016987(CASP10)

GAS:	123241894(CASP10)

SHR:	100930260(CASP10)

AFZ:

127553229

PCW:	110197140(CASP10)

OAA:

100092695

GGA:	424081(CASP10)

PCOC:

116233976(CASP10)

MGP:	100550034(CASP10)

CJO:	107316521(CASP10)

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:

LSR:	110484588(CASP10)

SCAN:

103814509(CASP10)

PMOA:

120499262(CASP10)

OTC:	121335317(CASP10)

PRUF:

121356473

GFR:	102044879(CASP10)

FAB:	101815409(CASP10)

OMA:	130255262(CASP10)

PHI:	102103849(CASP10)

PMAJ:

107207334(CASP10)

CCAE:

111931987(CASP10)

CCW:

104693775

CBRC:

103612146

ZAB:	102073289(CASP10)

SVG:

106855085

MMEA:

130579153

HRT:

120754974

FPG:	101918719(CASP10)

FCH:	102057122(CASP10)

CLV:	102085114(CASP10)

EGZ:	104130512(CASP10)

NNI:	104010195(CASP10)

PCRI:

104026021(CASP10)

PLET:

104623374(CASP10)

EHS:

104507514

PCAO:

104042979(CASP10)

ACUN:

113482525

TALA:

104359794

PADL:

103923449(CASP10)

AFOR:

103903457

ACHC:

115343323(CASP10)

HALD:

104322667(CASP10)

HLE:	104830062(CASP10)

AGEN:

126047422

GCL:

127018711

CCRI:

104163888(CASP10)

CMAC:

104485082(CASP10)

BREG:

104631028

FGA:

104082183

GSTE:

104255506(CASP10)

LDI:	104346355(CASP10)

MNB:	103775951(CASP10)

OHA:	104334214(CASP10)

NNT:	104409388(CASP10)

SHAB:

115607874(CASP10)

DPUB:

104296668(CASP10)

PGUU:

104465712(CASP10)

ACAR:

104523965(CASP10)

CPEA:

104397387

AVIT:

104280784(CASP10)

CVF:	104290990(CASP10)

RTD:	128912439(CASP10)

CUCA:

104058322(CASP10)

TEO:

BRHI:

AAM:

AROW:

NPD:

TGT:	104577125(CASP10)

DNE:	112987710(CASP10)

SCAM:

104150168

ASN:	102380890(CASP10)

AMJ:	102573990(CASP10)

CPOO:

109322724

GGN:	109301899(CASP10)

PSS:

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

MRV:

ACS:	100564281(casp10)

ASAO:

132779600(CASP10)

PVT:

110089021

SUND:

121934703(CASP10)

PBI:

103052358

PMUR:

107296977(CASP10)

CTIG:

120312832(CASP10)

TSR:	106547531(CASP10)

PGUT:

117673283

APRI:

131199572

PTEX:

113433951(CASP10)

VKO:	123024246(CASP10)

PMUA:

114584652

PRAF:

128399470(CASP10)

ZVI:

118095885

HCG:	128337913(CASP10)

GJA:

107122423

EMC:

129324564

XLA:	397820(casp10.S) 398762(casp10.L)

XTR:	548432(casp10)

NPR:

108795087

RTEM:

120943729(CASP10)

BBUF:

BGAR:

MUO:

GSH:

SRX:

AMEX:

EEE:

MALB:

SASA:

AANG:

118222447(casp10)

ARUT:

117408574 117426544

CPLA:

122551461

HOC:	132817233 132817282

LERI:

129698953

PMRN:

116938840(CASP10)

LRJ:

133345825

BBEL:

109462052 109464410 109465186 109475257 109479913

HHAL:

106684022

PJA:	122244006 122244008 122244009 122261469 122261470

PCHN:

125037021 125037022 125037023 125037225

UDV:

129218103

SDM:

118205802

LGI:	LOTGIDRAFT_53303

PVUL:

126808713

GAE:	121385161 121387653

HRJ:

PMAX:

MMER:

OSN:

ADF:

AMIL:

Reference

PMID:10187817

Authors

Ng PW, Porter AG, Janicke RU

Title

Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10.

Journal

J Biol Chem 274:10301-8 (1999)
DOI:10.1074/jbc.274.15.10301

Reference

PMID:20735596

Authors

Sakamaki K, Satou Y

Title

Caspases: evolutionary aspects of their functions in vertebrates.

Journal

J Fish Biol 74:727-53 (2009)
DOI:10.1111/j.1095-8649.2009.02184.x

Reference

PMID:18602321

Authors

Chowdhury I, Tharakan B, Bhat GK

Title

Caspases - an update.

Journal

Comp Biochem Physiol B Biochem Mol Biol 151:10-27 (2008)
DOI:10.1016/j.cbpb.2008.05.010

Reference

PMID:11717445

Authors

Wang J, Chun HJ, Wong W, Spencer DM, Lenardo MJ

Title

Caspase-10 is an initiator caspase in death receptor signaling.

Journal

Proc Natl Acad Sci U S A 98:13884-8 (2001)
DOI:10.1073/pnas.241358198

Sequence

[hsa:843]

LinkDB

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