KEGG   DRUG: DopamineHelp
Entry
D07870                      Drug                                   

Name
Dopamine (INN);
Medopa (TN)
Formula
C8H11NO2
Exact mass
153.079
Mol weight
153.1784
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01699  Catecholamine cardiotonic
 DG01592  COMT substrate
Neuropsychiatric agent
 DG01472  Dopamine agonist
  DG01467  Dopamine D1-receptor agonist
  DG01468  Dopamine D2-receptor agonist
  DG01469  Dopamine D3-receptor agonist
  DG01470  Dopamine D4-receptor agonist
  DG01471  Dopamine D5-receptor agonist
Unclassified
 DG02854  SLC22A2 substrate
Remark
Same as: C03758
ATC code: C01CA04
Chemical structure group: DG00213
Product (DG00213): D00633<JP/US>
Efficacy
Cardiotonic, Dopamine receptor agonist
Comment
Catecholamine derivative
Precursor of Norepinephrine
Neurotransmitter
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Metabolism
Enzyme: MAOB [HSA:4129], COMT [HSA:1312]
Transporter: SLC22A2 [HSA:6582]
Interaction
Drug interaction
Structure map
map07213  Dopamine receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA04 Dopamine
      D07870  Dopamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD
     D07870  Dopamine (INN)
Prodrugs [br08324.html]
 D07870
BRITE hierarchy
Other DBs
CAS: 51-61-6
PubChem: 96024566
ChEBI: 18243
ChEMBL: CHEMBL59
DrugBank: DB00988
PDB-CCD: LDP[PDBj]
LigandBox: D07870
NIKKAJI: J4.120C
LinkDB All DBs
KCF data Show

ATOM        11
            1   C8y C    27.5800  -20.4400
            2   C8x C    26.3200  -19.7400
            3   C8x C    27.5800  -21.9100
            4   C1b C    28.8400  -19.7400
            5   C8y C    25.1300  -20.4400
            6   C8x C    26.3200  -22.6100
            7   C1b C    30.0300  -20.4400
            8   C8y C    25.1300  -21.9100
            9   O1a O    23.9400  -19.7400
            10  N1a N    31.2200  -19.7400
            11  O1a O    23.9400  -22.5400
BOND        11
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11    6   8 2

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