KEGG   ORTHOLOGY: K06450
Entry
K06450                      KO                                     
Symbol
CD3D
Name
T-cell surface glycoprotein CD3 delta chain
Pathway
map04640  Hematopoietic cell lineage
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map05142  Chagas disease
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05340  Primary immunodeficiency
Disease
H00091  T-B+Severe combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   04660 T cell receptor signaling pathway
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   04658 Th1 and Th2 cell differentiation
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   04659 Th17 cell differentiation
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   05170 Human immunodeficiency virus 1 infection
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   05162 Measles
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   05169 Epstein-Barr virus infection
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
  09163 Immune disease
   05340 Primary immunodeficiency
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
CD molecules [BR:ko04090]
 Proteins
  K06450  CD3d; CD3D antigen, delta polypeptide (TiT3 complex)
Genes
HSA: 915(CD3D)
PTR: 451584(CD3D)
PPS: 100979946(CD3D)
GGO: 101150395(CD3D)
PON: 100440740(CD3D)
NLE: 100603907(CD3D)
MCC: 699582(CD3D)
MCF: 102133701(CD3D)
CSAB: 103248585(CD3D)
CATY: 105582471(CD3D)
PANU: 101017443(CD3D)
TGE: 112606384(CD3D)
RRO: 104665574(CD3D)
RBB: 108536385(CD3D)
TFN: 117080882(CD3D)
PTEH: 111540206(CD3D)
CJC: 100404313(CD3D)
SBQ: 101029738(CD3D)
CSYR: 103252246(CD3D)
MMUR: 105876053(CD3D)
OGA: 100966280(CD3D)
MMU: 12500(Cd3d)
MCAL: 110302262(Cd3d)
MPAH: 110328514(Cd3d)
RNO: 25710(Cd3d)
MCOC: 116072408(Cd3d)
MUN: 110549118(Cd3d)
CGE: 100756906(Cd3d)
PLEU: 114691294(Cd3d)
NGI: 103748303(Cd3d)
HGL: 101712534(Cd3d)
CPOC: 100727506(Cd3d)
CCAN: 109699106(Cd3d)
DORD: 105980551(Cd3d)
DSP: 122110306(Cd3d)
NCAR: 124958813
OCU: 100356153(CD3D)
OPI: 101529860(CD3D)
TUP: 102498607(CD3D)
CFA: 479419(CD3D)
VVP: 112920226(CD3D)
VLG: 121500522(CD3D)
AML: 100484718(CD3D)
UMR: 103662337(CD3D)
UAH: 113260002(CD3D)
UAR: 123792618(CD3D)
ELK: 111153823
LLV: 125080069
MPUF: 101676392(CD3D)
ORO: 101385969(CD3D)
EJU: 114211431(CD3D)
ZCA: 113914770(CD3D)
MLX: 118013287(CD3D)
FCA: 101083107(CD3D)
PYU: 121035465(CD3D)
PBG: 122483025(CD3D)
PTG: 102969057(CD3D)
PPAD: 109278564(CD3D)
AJU: 106966153(CD3D)
HHV: 120229959(CD3D)
BTA: 281053(CD3D)
BOM: 102272573(CD3D)
BIU: 109569960(CD3D)
BBUB: 102390133(CD3D)
CHX: 102191154(CD3D)
OAS: 443397(CD3D)
ODA: 120876320(CD3D)
CCAD: 122450232(CD3D)
SSC: 396661(CD3D)
CFR: 102505672(CD3D)
CBAI: 105067818(CD3D)
CDK: 105090171(CD3D)
VPC: 102533755(CD3D)
BACU: 103003761(CD3D)
LVE: 103069825(CD3D)
OOR: 101279567(CD3D)
DLE: 111166923(CD3D)
PCAD: 102979567(CD3D)
PSIU: 116758073(CD3D)
ECB: 100062931(CD3D)
EPZ: 103546675(CD3D)
EAI: 106840277(CD3D)
MYB: 102240563(CD3D)
MYD: 102753304(CD3D)
MMYO: 118664240(CD3D)
MLF: 102436834(CD3D)
MNA: 107530792(CD3D)
PKL: 118710562(CD3D)
HAI: 109385283(CD3D)
DRO: 112314228(CD3D)
SHON: 118994764(CD3D)
AJM: 119050808(CD3D)
PDIC: 114500133(CD3D)
PHAS: 123819998(CD3D)
MMF: 118628139(CD3D)
RFQ: 117029810(CD3D)
PALE: 102894486(CD3D)
PGIG: 120622049(CD3D)
PVP: 105310192(CD3D)
RAY: 107516062(CD3D)
MJV: 108385099(CD3D)
TOD: 119239888(CD3D)
SARA: 101545654(CD3D)
LAV: 100661471(CD3D)
TMU: 101353008
DNM: 101413471(CD3D)
MDO: 100031472(CD3D)
GAS: 123242099(CD3D)
SHR: 100925080
PCW: 110207189(CD3D)
OAA: 100090811
GGA: 396518(CD3D)
PCOC: 116233175(CD3D)
MGP: 100543119
CJO: 107324150
NMEL: 110387606
APLA: 101792606
ACYG: 106039849(CD3D)
AFUL: 116497897
TGU: 100222416
LSR: 110470410
SCAN: 103822979
PMOA: 120508489(CD3D)
OTC: 121340873
PRUF: 121348519
GFR: 102042200
FAB: 101820502
PHI: 102106764(CD3D)
PMAJ: 107214324
CCAE: 111939276
CCW: 104692179
ZAB: 102070969
FPG: 101916542(CD3D)
FCH: 102052093(CD3D)
CLV: 102092403(CD3D)
EGZ: 104124562
NNI: 104019039(CD3D)
ACUN: 113488514
TALA: 104362679
PADL: 103921538(CD3D)
ACHC: 115344581(CD3D)
AAM: 106491545(CD3D)
AROW: 112962044(CD3D)
NPD: 112948068(CD3D)
DNE: 112991715(CD3D)
ASN: 102382203(CD3D)
AMJ: 102572479(CD3D)
CPOO: 109315403(CD3D)
GGN: 109293913(CD3D)
CMY: 102940831(CD3G)
CPIC: 101940477
TST: 117868715
CABI: 116822944(CD3G)
MRV: 120375578
ACS: 103281391
SUND: 121935436
VKO: 123020236
ZVI: 118097067
GJA: 107112603(CD3G)
SRX: 107710511
SGH: 107557647
IPU: 108278320
TRU: 654302(cd3g/d)
MSAM: 119883393
MZE: 101473769(cd3g)
XMA: 111611912
XCO: 114133423
NFU: 107372866
ALIM: 106521072
CSEM: 103377691
SDU: 111232852
XGL: 120792558
OTW: 112266839
OMY: 110503669
SALP: 111957658
LOC: 107075658(cd3d)
RTP: 109926251
 » show all
Reference
PMID:3488209
  Authors
Tunnacliffe A, Sims JE, Rabbitts TH
  Title
T3 delta pre-mRNA is transcribed from a non-TATA promoter and is alternatively spliced in human T cells.
  Journal
EMBO J 5:1245-52 (1986)
DOI:10.1002/j.1460-2075.1986.tb04353.x
  Sequence
[hsa:915]
Reference
  Authors
de Saint Basile G, Geissmann F, Flori E, Uring-Lambert B, Soudais C, Cavazzana-Calvo M, Durandy A, Jabado N, Fischer A, Le Deist F
  Title
Severe combined immunodeficiency caused by deficiency in either the delta or the epsilon subunit of CD3.
  Journal
J Clin Invest 114:1512-7 (2004)
DOI:10.1172/JCI22588
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