| Entry |
|
|---|
| Name |
Dexpramipexole (USAN/INN) |
|---|
| Formula |
C10H17N3S
|
|---|
| Exact mass |
211.1143
|
|---|
| Mol weight |
211.33
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
|
|---|
| Efficacy |
Dopamine receptor agonist |
|---|
| Comment |
R(+) enantiomer of Pramipexole [DR: D05575]
Treatment of amyotrophic lateral sclerosis (ALS)
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD
D09886 Dexpramipexole (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 14
1 C1y C 18.6900 -21.0700
2 C1x C 18.6900 -22.4700
3 C1x C 19.9024 -23.1700
4 C8y C 21.1149 -22.4700
5 C8y C 21.1149 -21.0700
6 C1x C 19.9024 -20.3700
7 N5x N 22.4464 -22.9026
8 C8y C 23.2693 -21.7700
9 S2x S 22.4464 -20.6374
10 N1a N 24.6400 -21.7700
11 N1b N 17.4776 -20.3700
12 C1b C 16.2821 -21.0604
13 C1b C 15.0947 -20.3749
14 C1a C 13.9035 -21.0629
BOND 15
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 5 9 1
11 8 10 1
12 1 11 1 #Up
13 11 12 1
14 12 13 1
15 13 14 1
|
|---|
