| Entry |
|
| Symbol |
EXT2
|
| Name |
|
| Pathway |
| map00534 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
|
| Module |
| M00059 | Glycosaminoglycan biosynthesis, heparan sulfate backbone |
|
| Reaction |
|
| Disease |
| H00493 | Heparan sulfate proteoglycan gene defects |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
K02367 EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases
K02367 EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
Enzymes [BR:ko01000]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
K02367 EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
2.4.1.225 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
K02367 EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
Glycosyltransferases [BR:ko01003]
Glycan extension
O-Glycan
K02367 EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
Glycosyltransferase reactions [br08203.html]
N-Acetylglucosaminyltransferase reactions
K02367
Glucuronyltransferase reactions
K02367
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Lind T, Tufaro F, McCormick C, Lindahl U, Lidholt K |
| Title |
The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate. |
| Journal |
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| Sequence |
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| LinkDB |
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