KEGG   ORTHOLOGY: K02373
Entry
K02373                      KO                                     
Symbol
FADD
Name
FAS-associated death domain protein
Pathway
map01524  Platinum drug resistance
map04210  Apoptosis
map04215  Apoptosis - multiple species
map04217  Necroptosis
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04624  Toll and Imd signaling pathway
map04657  IL-17 signaling pathway
map04668  TNF signaling pathway
map04936  Alcoholic liver disease
map05010  Alzheimer disease
map05022  Pathways of neurodegeneration - multiple diseases
map05130  Pathogenic Escherichia coli infection
map05132  Salmonella infection
map05142  Chagas disease
map05152  Tuberculosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    K02373  FADD; FAS-associated death domain protein
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K02373  FADD; FAS-associated death domain protein
   04215 Apoptosis - multiple species
    K02373  FADD; FAS-associated death domain protein
   04217 Necroptosis
    K02373  FADD; FAS-associated death domain protein
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K02373  FADD; FAS-associated death domain protein
   04624 Toll and Imd signaling pathway
    K02373  FADD; FAS-associated death domain protein
   04621 NOD-like receptor signaling pathway
    K02373  FADD; FAS-associated death domain protein
   04622 RIG-I-like receptor signaling pathway
    K02373  FADD; FAS-associated death domain protein
   04657 IL-17 signaling pathway
    K02373  FADD; FAS-associated death domain protein
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02373  FADD; FAS-associated death domain protein
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K02373  FADD; FAS-associated death domain protein
   05161 Hepatitis B
    K02373  FADD; FAS-associated death domain protein
   05160 Hepatitis C
    K02373  FADD; FAS-associated death domain protein
   05164 Influenza A
    K02373  FADD; FAS-associated death domain protein
   05162 Measles
    K02373  FADD; FAS-associated death domain protein
   05168 Herpes simplex virus 1 infection
    K02373  FADD; FAS-associated death domain protein
   05163 Human cytomegalovirus infection
    K02373  FADD; FAS-associated death domain protein
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02373  FADD; FAS-associated death domain protein
   05169 Epstein-Barr virus infection
    K02373  FADD; FAS-associated death domain protein
   05165 Human papillomavirus infection
    K02373  FADD; FAS-associated death domain protein
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K02373  FADD; FAS-associated death domain protein
   05132 Salmonella infection
    K02373  FADD; FAS-associated death domain protein
   05152 Tuberculosis
    K02373  FADD; FAS-associated death domain protein
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K02373  FADD; FAS-associated death domain protein
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02373  FADD; FAS-associated death domain protein
   05022 Pathways of neurodegeneration - multiple diseases
    K02373  FADD; FAS-associated death domain protein
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K02373  FADD; FAS-associated death domain protein
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    K02373  FADD; FAS-associated death domain protein
Genes
HSA: 8772(FADD)
PTR: 451389(FADD)
PPS: 100968673(FADD)
GGO: 101134274(FADD)
PON: 100439256(FADD)
NLE: 100607557(FADD)
MCC: 708606(FADD)
MCF: 101866285(FADD)
CSAB: 103245758(FADD)
CATY: 105577297(FADD)
PANU: 101017433(FADD)
TGE: 112606728(FADD)
RRO: 104677132(FADD)
RBB: 108538801(FADD)
TFN: 117079989(FADD)
PTEH: 111522332(FADD)
CJC: 100410616(FADD)
SBQ: 101046905(FADD)
CSYR: 103262441(FADD)
MMUR: 105867530(FADD)
OGA: 100960309(FADD)
MMU: 14082(Fadd)
MCAL: 110298222(Fadd)
MPAH: 110333124(Fadd)
RNO: 266610(Fadd)
MCOC: 116103283(Fadd)
MUN: 110546885(Fadd)
CGE: 100774599(Fadd)
MAUA: 101839512(Fadd)
PLEU: 114694438(Fadd)
MORG: 121457709(Fadd)
NGI: 103751502(Fadd)
HGL: 101709972(Fadd)
CPOC: 100730628(Fadd)
CCAN: 109700274(Fadd)
DORD: 105989060(Fadd) 106002598
DSP: 122099877(Fadd)
NCAR: 124960510
OCU: 103346753(FADD)
OPI: 101521668(FADD)
TUP: 102489799(FADD)
CFA: 611694(FADD)
VVP: 112924009(FADD)
VLG: 121471748(FADD)
AML: 100468003(FADD)
UMR: 103671072(FADD)
UAH: 113243978(FADD)
UAR: 123778464(FADD)
ELK: 111149616
LLV: 125079328
MPUF: 101671860(FADD)
ORO: 101385048(FADD)
EJU: 114220353(FADD)
ZCA: 113914747(FADD) 113931151
MLX: 118016168(FADD)
FCA: 101087871(FADD)
PYU: 121023867(FADD)
PBG: 122484102(FADD)
PPAD: 109246999(FADD)
AJU: 106982870(FADD)
HHV: 120233869(FADD)
BTA: 493720(FADD)
BOM: 102271962(FADD)
BIU: 109554562(FADD)
BBUB: 102397985(FADD)
CHX: 102170760(FADD)
OAS: 101116783(FADD)
ODA: 120874152(FADD)
CCAD: 122431085(FADD)
SSC: 595129(FADD)
CFR: 102519266(FADD)
CBAI: 105070436(FADD)
CDK: 105104389(FADD)
BACU: 103014148(FADD)
LVE: 103080339(FADD)
OOR: 101272962(FADD)
DLE: 111183629(FADD)
PSIU: 116757390(FADD)
ECB: 100061802(FADD)
EPZ: 103566999(FADD)
EAI: 106822169(FADD)
MYD: 102756704(FADD)
MMYO: 118665178(FADD)
MLF: 111824600(FADD)
MNA: 107542171(FADD)
PKL: 118713371(FADD)
HAI: 109389315(FADD)
DRO: 112317320(FADD)
SHON: 118998399(FADD)
AJM: 119041863(FADD)
PDIC: 114489990(FADD)
PHAS: 123829338(FADD)
MMF: 118628258(FADD)
RFQ: 117030152(FADD)
PALE: 102892511(FADD)
PGIG: 120584707(FADD)
PVP: 105307475(FADD)
RAY: 107503382(FADD)
MJV: 108401442
TOD: 119250504(FADD)
SARA: 101537769(FADD)
LAV: 100662633(FADD)
TMU: 101352734
DNM: 101415698(FADD)
MDO: 100031941(FADD)
GAS: 123256276(FADD)
SHR: 100925732(FADD)
PCW: 110197147(FADD)
OAA: 100075638(FADD)
GGA: 423146(FADD)
PCOC: 116229092(FADD)
MGP: 100540536(FADD)
CJO: 107314471(FADD)
NMEL: 110401719(FADD)
APLA: 101801863(FADD)
ACYG: 106044712(FADD)
AFUL: 116489918(FADD)
TGU: 100229649(FADD)
LSR: 110485062(FADD)
SCAN: 103822220(FADD)
PMOA: 120509904(FADD)
OTC: 121340228(FADD)
PRUF: 121349102(FADD)
GFR: 102042362(FADD)
FAB: 101806236(FADD)
PHI: 102102219(FADD)
PMAJ: 107205253(FADD)
CCAE: 111930654(FADD)
CCW: 104697634(FADD)
ETL: 114070411(FADD)
ZAB: 102064080(FADD)
FPG: 101918701(FADD)
FCH: 102055286(FADD)
CLV: 102085703(FADD)
EGZ: 104124706(FADD)
NNI: 104009489(FADD)
ACUN: 113481356(FADD)
TALA: 104358040(FADD)
PADL: 103925771(FADD)
ACHC: 115351998(FADD)
AAM: 106498371(FADD)
AROW: 112977257(FADD)
NPD: 112943547(FADD)
DNE: 112979977(FADD)
ASN: 102377608(FADD)
AMJ: 102572187(FADD)
CPOO: 109321492(FADD)
GGN: 109298988(FADD)
PSS: 102448271(FADD)
CMY: 102930159(FADD)
CPIC: 101944927(FADD)
TST: 117877033(FADD)
CABI: 116822548(FADD)
MRV: 120402879(FADD)
ACS: 103279978(fadd)
PVT: 110073515(FADD)
PBI: 103054174(FADD)
PMUR: 107287485(FADD)
TSR: 106546194(FADD)
PGUT: 117665438(FADD)
VKO: 123026823(FADD)
PMUA: 114596831(FADD)
ZVI: 118085907(FADD)
GJA: 107118889(FADD)
STOW: 125427570(FADD)
XLA: 108713779(fadd.L) 496403(fadd.S)
XTR: 100379789(fadd)
NPR: 108785454(FADD)
RTEM: 120917101(FADD)
BBUF: 120980177(FADD)
BGAR: 122920804(FADD)
DRE: 562317(fadd)
CCAR: 109047225(fadd)
CAUA: 113051795 113106512(fadd)
PPRM: 120492744(fadd)
MAMB: 125265402(fadd)
IPU: 100305064(fadd)
PHYP: 113536458(fadd)
SMEO: 124391257(fadd)
TFD: 113646637(fadd)
AMEX: 103022073(fadd)
EEE: 113578454(fadd)
LCO: 104933825
NCC: 104955074(fadd)
CGOB: 115025685(fadd)
ELY: 117258051(fadd)
PLEP: 121964874
SLUC: 116045235(fadd)
ECRA: 117942648(fadd)
PFLV: 114558921(fadd)
GAT: 120832244(fadd)
MSAM: 119890367(fadd)
CUD: 121512063(fadd)
ALAT: 119017669(fadd)
MZE: 101483780(fadd)
ONL: 100706963(fadd)
OAU: 116323704(fadd)
OLA: 100049399(fadd)
OML: 112160870(fadd)
XMA: 102230597(fadd)
XCO: 114143134(fadd)
XHE: 116719102(fadd)
PFOR: 103150957(fadd)
PLAI: 106943302(fadd)
PMEI: 106912590(fadd)
GAF: 122845769(fadd)
CVG: 107101768
CTUL: 119772677(fadd)
GMU: 124867141(fadd)
NFU: 107372902
KMR: 108237856(fadd)
ALIM: 106526561
NWH: 119430211(fadd)
AOCE: 111583532(fadd)
CSEM: 103378588(fadd)
POV: 109625113(fadd)
SSEN: 122772852(fadd)
HHIP: 117759449(fadd)
HSP: 118105702(fadd)
LCF: 108880505
SDU: 111218782(fadd)
XGL: 120800498(fadd)
BPEC: 110174542(fadd)
MALB: 109967863(fadd)
BSPL: 114852435(fadd)
SASA: 106561969(FADD) 106587129(FADD)
OTW: 112249032(fadd) 112263517
OMY: 110506335 110526221(fadd)
OGO: 124033904(fadd) 124034867
ELS: 105017350(fadd)
SFM: 108941100(fadd)
PKI: 111851812(fadd)
AANG: 118226682(fadd)
LOC: 102690370(fadd)
PSPA: 121329520(fadd)
ARUT: 117431917(fadd) 117435159
LCM: 102357786(FADD)
CMK: 103175018(fadd)
RTP: 109916874(fadd)
DME: Dmel_CG12297(Fadd)
DER: 6555409
DSE: 6607373
DSI: Dsimw501_GD20917(Dsim_GD20917)
DAN: 6500843
DSR: 110191152
DPE: 6588586
DMN: 108157384
DWI: 6643008
DGR: 6558978
DAZ: 108614180
DNV: 108651126
DVI: 6622474
CCAT: 101463172
BOD: 106616273
MDE: 101896030
SCAC: 106092574
LCQ: 111686266
LSQ: 119609458
AGA: AgaP_AGAP007173(FADD)
ACOZ: 120948741
AARA: 120898144
ASTE: 118510269
AAG: 5573014
CPII: 120418662
AME: 100577690
ACER: 108003772
ALAB: 122717754
BIM: 100745977
BBIF: 117205207
BVK: 117230284
BVAN: 117161589
BTER: 100648684
BPYO: 122572138
CCAL: 108622920
OBB: 114874892
MGEN: 117223502
CGIG: 122401582
SOC: 105196497
MPHA: 105838903
AEC: 105152731
ACEP: 105620481
PBAR: 105430419
VEM: 105559261
HST: 105183935
DQU: 106740719
CFO: 105256948
FEX: 115233437
LHU: 105676271
PGC: 109864088
OBO: 105281606
PCF: 106787442
PFUC: 122522263
VPS: 122634470
NVI: 103315410
TPRE: 106650617
MDL: 103573921
CGLO: 123268797
FAS: 105266918
DAM: 107045938
AGIF: 122856009
CCIN: 107272838
TCA: 103312947(Fadd)
DPA: 109537323
SOY: 115876310
ATD: 109602827
CSET: 123311854
AGB: 108915819
NVL: 108560749
APLN: 108732977
PPYR: 116168695
OTU: 111427930
BMOR: 100529236
BMAN: 114251337
MSEX: 115441066
BANY: 112057681
PMAC: 106714892
PPOT: 106105505
PXU: 106125143
PRAP: 111000403
ZCE: 119831035
HAW: 110378975
TNL: 113502307
SLIU: 111349206
OFU: 114365425
FOC: 113213861
ZNE: 110837312
CSEC: 111869311
DMK: 116924366
PCAN: 112577048
BGT: 106062358
CRG: 105323317
MYI: 110449934
OBI: 106871748
ATEN: 116286535
PDAM: 113684812
DGT: 114517686
AQU: 100633090
 » show all
Reference
PMID:7538907
  Authors
Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM
  Title
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
  Journal
Cell 81:505-12 (1995)
DOI:10.1016/0092-8674(95)90071-3
  Sequence
[hsa:8772]
Reference
  Authors
Bolze A, Byun M, McDonald D, Morgan NV, Abhyankar A, Premkumar L, Puel A, Bacon CM, Rieux-Laucat F, Pang K, Britland A, Abel L, Cant A, Maher ER, Riedl SJ, Hambleton S, Casanova JL
  Title
Whole-exome-sequencing-based discovery of human FADD deficiency.
  Journal
Am J Hum Genet 87:873-81 (2010)
DOI:10.1016/j.ajhg.2010.10.028
  Sequence
[hsa:8772]
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