KEGG   ORTHOLOGY: K04127
Entry
K04127                      KO                                     
Symbol
cefD
Name
isopenicillin-N epimerase [EC:5.1.1.17]
Pathway
map00311  Penicillin and cephalosporin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00673  Cephamycin C biosynthesis, aminoadipate + cycteine + valine => cephamycin C
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00311 Penicillin and cephalosporin biosynthesis
    K04127  cefD; isopenicillin-N epimerase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K04127  cefD; isopenicillin-N epimerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.1  Acting on amino acids and derivatives
    5.1.1.17  isopenicillin-N epimerase
     K04127  cefD; isopenicillin-N epimerase
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide tailoring proteins
  Others
   K04127  cefD; isopenicillin-N epimerase
Other DBs
RN: R04147
GO: 0045439
Genes
XCC: XCC1212(nifS)
XCB: XC_3030
XCA: xcc-b100_3093(cefD)
XCP: XCR_1454
XAX: XACM_1285
XPE: BJD13_10100
RSO: RSp0696
RSC: RCFBP_10279
RSL: RPSI07_mp0854(cefD)
RSN: RSPO_c00320(cefD)
RSY: RSUY_02990(cefD)
BMA: BMAA0692
BMAL: DM55_4745
BMAE: DM78_3245
BMAQ: DM76_3699
BMAI: DM57_12105
BMAF: DM51_4398
BMAZ: BM44_4735
BMAB: BM45_4997
BPS: BPSS0826
BPM: BURPS1710b_A2417(cefD)
BPL: BURPS1106A_A1140(cefD)
BPSE: BDL_4112
BPSM: BBQ_5312
BPSU: BBN_4284
BPSD: BBX_5952
BPK: BBK_3615
BPSH: DR55_4511
BPSA: BBU_5206
BPSO: X996_4060
BUT: X994_3738
BTD: BTI_5642
BUL: BW21_5329
RGE: RGE_38680
MPAU: ZMTM_08360(cefD)
MXA: MXAN_5758(cefD)
CCX: COCOR_06250(cefD)
SUR: STAUR_6423(cefD)
SCL: sce8130
SHUM: STHU_41780(cefD)
SVC: STVA_45250(nifS)
STEL: STAQ_06800(nifS_2)
HTQ: FRZ44_45180(nifS)
HADH: FRZ61_42820(nifS)
MMAG: MMAD_03810(cefD)
SGB: WQO_32335
SMAL: SMALA_2490
SCT: SCAT_5686(cefD)
SBH: SBI_00921
STRM: M444_06915
SGM: GCM10017557_05590(nifS)
SLAU: SLA_7034
SLX: SLAV_07070(cefD2)
SFK: KY5_0714
SGE: DWG14_07627(cefD_2)
SNF: JYK04_06931(cefD)
MOY: CVS54_03345(cefD)
ARM: ART_1339
TLA: TLA_TLA_01558(cefD)
KFL: Kfla_3594
SRO: Sros_3487
KRA: Krad_0174
AMYY: YIM_39195(cefD)
MIL: ML5_1645
ASE: ACPL_7270(cefD)
ACTN: L083_6863(cefD)
AFS: AFR_36275
ACTS: ACWT_7140
CAI: Caci_5559
SNA: Snas_2195
CYA: CYA_0818(cefD)
CYB: CYB_1874(cefD)
LET: O77CONTIG1_02952(cefD_2)
LBO: LBWT_6690
MAR: MAE_52910
MPK: VL20_1539
NSH: GXM_02799
CALH: IJ00_06455
RCA: Rcas_3584
CAU: Caur_1659
CAG: Cagg_2502
ATM: ANT_18540
MRB: Mrub_1746
RBA: RB7564(cefD)
PSL: Psta_2194
PIR: VN12_10170(cefD)
RML: FF011L_05920(cefD)
MFF: MFFC18_08200(cefD)
ROL: CA51_19080(cefD)
LCRE: Pla8534_29080(cefD)
AAGG: ETAA8_46010(cefD_1)
BVO: Pan97_28140(cefD)
RLC: K227x_38360(cefD)
AMUC: Pan181_34570(cefD)
PLM: Plim_1607
PEH: Spb1_24620(cefD)
PLS: VT03_15840(cefD)
FMR: Fuma_05761(cefD)
MRI: Mal4_46350(cefD)
SDYN: Mal52_22760(cefD)
PLON: Pla110_41390(cefD)
GES: VT84_18005(cefD)
FTJ: FTUN_5065
ULI: ETAA1_15630(cefD)
IPA: Isop_2866
ABAC: LuPra_04390(cefD_4)
FSN: GS03_01086(cefD)
AG: AAA26714(cefD)
 » show all
Reference
PMID:1694525
  Authors
Kovacevic S, Tobin MB, Miller JR
  Title
The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerus.
  Journal
J Bacteriol 172:3952-8 (1990)
DOI:10.1128/JB.172.7.3952-3958.1990
  Sequence
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