KEGG ORTHOLOGY: K10261

ORTHOLOGY: K10261

Entry

K10261                      KO

Symbol

FBXW2, MD6

Name

F-box and WD-40 domain protein 2

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10261  FBXW2, MD6; F-box and WD-40 domain protein 2
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit type E3
   SCF complex
    Target recognizing subunit (F-box)
     K10261  FBXW2, MD6; F-box and WD-40 domain protein 2

Genes

HSA:	26190(FBXW2)

PTR:	464698(FBXW2)

PPS:	100982748(FBXW2)

GGO:	101154243(FBXW2)

PON:	100460052(FBXW2)

PPYG:

129044686(FBXW2)

NLE:	100603649(FBXW2)

HMH:	116475598(FBXW2)

SSYN:

129478952(FBXW2)

MCC:	700958(FBXW2)

MCF:	102130144(FBXW2)

MTHB:

126937640

MNI:	105484090 105487137(FBXW2)

CSAB:

103218921(FBXW2)

CATY:

105600327(FBXW2)

PANU:

101004406(FBXW2)

TGE:	112608049(FBXW2)

MLEU:

105546337(FBXW2)

RRO:	104669127(FBXW2)

RBB:	108524713 108537077(FBXW2) 108539303

TFN:	117080440 117098749(FBXW2)

PTEH:

111550320(FBXW2)

CANG:

105501441(FBXW2)

CJC:	100387180(FBXW2)

SBQ:	101050625(FBXW2)

CIMI:

108285837(FBXW2)

ANAN:

105721255(FBXW2)

CSYR:

103258064(FBXW2)

MMUR:

105875115(FBXW2)

LCAT:

123645744(FBXW2)

PCOQ:

105826454(FBXW2)

OGA:	100958032(FBXW2)

MMU:	30050(Fbxw2)

MCAL:

110289595(Fbxw2)

MPAH:

110317730(Fbxw2)

RNO:	311881(Fbxw2)

MCOC:

116090047(Fbxw2)

ANU:	117702996(Fbxw2)

ASYL:

127685271(Fbxw2)

MUN:	110563755(Fbxw2)

CGE:

100756088

MAUA:

101823582(Fbxw2) 121138140

PROB:

127222811(Fbxw2)

PLEU:

114704695(Fbxw2)

MORG:

121462864(Fbxw2)

MFOT:

126513348

AAMP:

119804201 119818510(Fbxw2)

NGI:	103734499(Fbxw2)

HGL:	101724545(Fbxw2)

CPOC:

100723973(Fbxw2)

CCAN:

109692161(Fbxw2)

DORD:

105996126(Fbxw2)

DSP:	122107056(Fbxw2)

PLOP:

125347764(Fbxw2)

NCAR:

124964351

MMMA:

107152140(Fbxw2)

ITI:	101957114(Fbxw2)

OCU:

100339343

OPI:	101530882(FBXW2)

TUP:	102490787(FBXW2)

GVR:	103587295(FBXW2)

CFA:	610990(FBXW2)

CLUD:

112649632(FBXW2)

VVP:	112923104(FBXW2)

VLG:	121495767(FBXW2)

NPO:	129494723(FBXW2)

AML:	100483667(FBXW2)

UMR:	103670375(FBXW2)

UAH:	113266347(FBXW2)

UAR:	123788024(FBXW2)

ELK:

111145634

LLV:

125083966

MPUF:

101688362(FBXW2)

MNP:	132024466(FBXW2)

MLK:	131813249(FBXW2)

NVS:	122917307(FBXW2)

ORO:	101362967(FBXW2)

EJU:	114212723(FBXW2)

ZCA:	113934249(FBXW2)

MLX:	118017755(FBXW2)

NSU:	110581423(FBXW2)

LWW:	102739342(FBXW2)

FCA:	101086186(FBXW2)

PYU:	121014127 121034905(FBXW2)

PCOO:

112850758(FBXW2)

PBG:	122475084(FBXW2)

PVIV:

125150087(FBXW2)

LRUF:

124503559 124529370

LGF:	123593667 123593741(FBXW2)

AJU:	106986630 128312272

PTG:	102960765(FBXW2)

PPAD:

109269896(FBXW2)

PUC:	125912181 125920803

PLEZ:

122204660(FBXW2) 122204776

HHV:	120233413(FBXW2)

BTA:	767863(FBXW2)

BOM:	102285880(FBXW2)

BBUB:

102397617(FBXW2)

BBIS:

104994771(FBXW2)

CHX:	102181301(FBXW2)

OAS:	101122758(FBXW2)

BTAX:

128052336(FBXW2)

CSUM:

138080956(FBXW2)

ODA:	120864761(FBXW2)

CCAD:

122431678(FBXW2)

MREE:

136176766(FBXW2)

OVR:	110127225 110137335(FBXW2)

MBEZ:

129557211(FBXW2)

SSC:	100155830(FBXW2)

CFR:	102511762(FBXW2)

CBAI:

105065271(FBXW2)

CDK:	105104526(FBXW2)

VPC:	102545819(FBXW2)

BACU:

103013261(FBXW2)

BMUS:

118896624(FBXW2)

LVE:	103087532(FBXW2)

OOR:	101280735(FBXW2)

LALB:

132523400(FBXW2)

DLE:	111177272(FBXW2)

PCAD:

102981358(FBXW2) 112061877

PSIU:

116755300(FBXW2)

NASI:

112411226(FBXW2)

ECB:	100067698(FBXW2)

EPZ:	103550356(FBXW2)

EAI:	106824197(FBXW2)

MYB:	102241087(FBXW2)

MYD:	102772052(FBXW2)

MMYO:

118667111(FBXW2)

MLF:	102439123(FBXW2)

MDT:	132212324(FBXW2)

MYUM:

139020819(FBXW2)

PKL:	118716104(FBXW2)

EFUS:

103295675(FBXW2)

MNA:	107537654(FBXW2)

DRO:	112306268(FBXW2)

SHON:

118995974(FBXW2)

AJM:	119035929(FBXW2)

PDIC:

114493909(FBXW2)

PHAS:

123819743(FBXW2)

MMF:	118629520(FBXW2)

PPAM:

129079312(FBXW2)

HAI:	109385734(FBXW2)

RFQ:	117031611(FBXW2)

PALE:

102895769(FBXW2)

PGIG:

120605777(FBXW2)

PVP:	105292658(FBXW2)

RAY:	107516328(FBXW2)

MJV:	108391149(FBXW2)

TOD:	119230930(FBXW2)

SARA:

101559252(FBXW2)

SFUM:

130045786(FBXW2)

SETR:

126008800(FBXW2)

LAV:	100677629(FBXW2)

TMU:

101351739

ETF:	101649643(FBXW2)

DNM:	101421360(FBXW2)

MDO:	100013249(FBXW2)

GAS:	123237380(FBXW2)

SHR:	100927895(FBXW2)

AFZ:

127550527

PCW:	110211349(FBXW2)

TVP:	118843914(FBXW2)

PBRV:

138150390(FBXW2)

OAA:	100073714(FBXW2)

TACU:

119927352(FBXW2)

GGA:	417088(FBXW2)

PCOC:

116234415(FBXW2)

MGP:	100540246(FBXW2)

CJO:	107321929(FBXW2)

TPAI:

128073985(FBXW2)

LMUT:

125702666(FBXW2)

NMEL:

110407028(FBXW2)

APLA:

101797176(FBXW2)

ACYG:

106040696(FBXW2)

CATA:

118252177(FBXW2)

AFUL:

116497060(FBXW2)

TGU:	100223074(FBXW2)

LSR:	110477694(FBXW2)

SCAN:

103818908(FBXW2)

PMOA:

120512416(FBXW2)

OTC:	121336847(FBXW2)

PRUF:

121362381(FBXW2)

ATRC:

139603232(FBXW2)

GFR:	102032267(FBXW2)

FAB:	101814375(FBXW2)

OMA:	130260202(FBXW2)

PHI:	102103448(FBXW2)

PMAJ:

107212028(FBXW2)

CCAE:

111937141(FBXW2)

CCW:	104688405(FBXW2)

CBRC:

103623086(FBXW2)

ACOE:

138119793(FBXW2)

ETL:	114061994(FBXW2)

ZAB:	102073658(FBXW2)

ZLE:	135454852(FBXW2)

ACHL:

103800003(FBXW2)

SVG:	106855406(FBXW2)

MMEA:

130583507(FBXW2)

HRT:	120761755(FBXW2)

SATI:

136369889(FBXW2)

CCIC:

134051827(FBXW2)

FPG:	101924593(FBXW2)

FCH:	102046131(FBXW2)

CCRI:

104155730(FBXW2)

NNT:	104400090(FBXW2)

SHAB:

115616942(FBXW2)

ACUN:

113486393(FBXW2)

TALA:

104358862(FBXW2)

ACHC:

115334949(FBXW2)

HALD:

104311867(FBXW2)

HLE:	104831360(FBXW2)

AGEN:

126052523

HHAR:

128154837(FBXW2)

GCL:

127023544

CSTI:

104551032(FBXW2)

LDI:	104340904(FBXW2)

MNB:	103772010(FBXW2)

DPUB:

104306521(FBXW2)

PPUS:

135190125(FBXW2)

AVIT:

104268317(FBXW2)

BRHI:

104490561(FBXW2)

EGZ:	104133997(FBXW2)

NNI:	104023240(FBXW2)

PCRI:

104025268(FBXW2)

PCAO:

104049472(FBXW2)

PADL:

103925491(FBXW2)

AFOR:

103899605(FBXW2)

FGA:	104070694(FBXW2)

GSTE:

104251954(FBXW2)

CBOY:

140661091(FBXW2)

CLV:	102098257(FBXW2)

MUI:	104534328(FBXW2)

PGUU:

104466889(FBXW2)

PLET:

104614852(FBXW2)

EHS:	104504092(FBXW2)

CMAC:

104474133(FBXW2)

CUCA:

104066875(FBXW2)

TEO:	104370453(FBXW2)

BREG:

104630296(FBXW2)

OHA:	104336290(FBXW2)

ACAR:

104520930(FBXW2)

CPEA:

104389769(FBXW2)

CVF:	104292869(FBXW2)

RTD:	128917566(FBXW2)

CRID:

134523656(FBXW2)

AAM:	106495047(FBXW2)

AROW:

112977613(FBXW2)

NPD:	112955971(FBXW2)

TGT:	104572017(FBXW2)

DNE:	112990447(FBXW2)

SCAM:

104149499(FBXW2)

ASN:	102374534(FBXW2)

AMJ:	102570081(FBXW2)

CPOO:

109314092(FBXW2)

GGN:	109295226(FBXW2)

PSS:	102458143(FBXW2)

CMY:	102937956(FBXW2)

CCAY:

125623696(FBXW2)

DCC:	119844093(FBXW2)

CPIC:

101949082(FBXW2)

TST:	117867246(FBXW2)

CABI:

116825089(FBXW2)

MRV:	120386753(FBXW2)

ACS:	100554130(fbxw2)

ASAO:

132763680(FBXW2)

PVT:	110082936(FBXW2)

SUND:

121937184(FBXW2)

PBI:	103055354(FBXW2)

PMUR:

107291053(FBXW2)

CTIG:

120300720(FBXW2)

TSR:	106552694(FBXW2)

PGUT:

117665091(FBXW2)

APRI:

131186123(FBXW2)

PTEX:

113444002(FBXW2)

NSS:	113426847(FBXW2)

VKO:	123028331(FBXW2)

PMUA:

114588949(FBXW2)

PRAF:

128406497(FBXW2)

ZVI:	118084096(FBXW2)

HCG:	128338776(FBXW2)

GJA:	107114381(FBXW2)

STOW:

125441881(FBXW2)

EMC:	129342664(FBXW2)

XLA:	108699918(fbxw2.S) 380189(fbxw2.L)

XTR:	496598(fbxw2)

NPR:	108791557(FBXW2)

RTEM:

120913795(FBXW2)

BBUF:

120977990(FBXW2)

BGAR:

122922620(FBXW2)

PWL:	138301332(FBXW2)

MUO:	115472975(FBXW2)

GSH:	117367927(FBXW2)

DRE:	553942(fbxw2)

SRX:	107723354 107740938

SANH:

107691038 107693864

SGH:	107587370 107597196

CCAR:

109080833(fbxw2) 122145170

CAUA:

113049357 113075384

CGIB:

127958305 128006879

PTET:

122345745(fbxw2)

LROH:

127165398(fbxw2)

OMC:	131541562(fbxw2)

PPRM:

120469724(fbxw2)

RKG:	130101599(fbxw2)

MAMB:

125267102(fbxw2)

CIDE:

127513190

CERY:

137033969(fbxw2)

MASI:

127422491 127440175

TROS:

130566558(fbxw2)

TDW:	130420204(fbxw2)

MANU:

129440271(fbxw2)

PDAB:

135748540 135753377

IPU:

108260331

IFU:	128603721(fbxw2)

PHYP:

113531582(fbxw2)

SMEO:

124378911(fbxw2)

TFD:	113655185(fbxw2)

TVC:	132840992(fbxw2)

CGAR:

128512531(fbxw2)

NGRA:

132876105(fbxw2)

TRN:	134303462(fbxw2)

AMEX:

103029011(fbxw2)

CMAO:

118802423(fbxw2)

EEE:	113583611(fbxw2)

CHAR:

105911106(fbxw2)

SPIL:

134100353(fbxw2)

TRU:	101071201(fbxw2)

TFS:	130516813(fbxw2)

TNG:	GSTEN00005173G001 GSTEN00005174G001

LCO:	104926490(fbxw2)

NCC:	104951156(fbxw2)

TBEN:

117479020(fbxw2)

CGOB:

115016804(fbxw2)

PGEO:

117456569(fbxw2)

GACU:

117534876(fbxw2)

EMAC:

134868988(fbxw2)

ELY:	117269532(fbxw2)

EFO:	125905829(fbxw2)

PLEP:

121959631(fbxw2)

SLUC:

116038189(fbxw2)

ECRA:

117959384(fbxw2)

ESP:	116686882(fbxw2)

PFLV:

114570885(fbxw2)

GAT:	120831950(fbxw2)

PPUG:

119226306(fbxw2)

AFB:	129102410(fbxw2)

CLUM:

117740598(fbxw2)

PSWI:

130205636(fbxw2)

CANA:

137784318(fbxw2)

CVE:	137869007(fbxw2)

MSAM:

119914632(fbxw2)

SCHU:

122865703(fbxw2)

CUD:	121525329(fbxw2)

SPUL:

138609602(fbxw2)

LMIX:

132992221(fbxw2)

ALAT:

119030371(fbxw2)

ASTR:

137608972(fbxw2)

MZE:	101470259(fbxw2)

ONL:	100709485(fbxw2)

OAU:	116319157(fbxw2)

OLA:	101171017(fbxw2)

OML:	112141706(fbxw2)

CSAI:

133454517(fbxw2)

XMA:	102224603(fbxw2)

XCO:	114150192(fbxw2)

XHE:	116724743(fbxw2)

PRET:

103473167(fbxw2)

PFOR:

103152294(fbxw2)

PLAI:

106947021(fbxw2)

PMEI:

106922485(fbxw2)

GAF:	122819678(fbxw2)

PPRL:

129379786(fbxw2)

CVG:	107104071(fbxw2)

CTUL:

119797754(fbxw2)

GMU:	124873095(fbxw2)

NFU:	107390277(fbxw2)

KMR:	108231096(fbxw2)

ALIM:

106526046(fbxw2)

NWH:	119425189(fbxw2)

AOCE:

111581031(fbxw2)

EJA:	138210077(fbxw2)

BFRE:

138632062(fbxw2)

MCEP:

124997005(fbxw2)

CSEM:

103389860(fbxw2)

POV:	109626491(fbxw2)

SSEN:

122758537(fbxw2)

SSOE:

131446676(fbxw2)

HHIP:

117771918(fbxw2)

HSP:	118125362(fbxw2)

PPLT:

128424530(fbxw2)

SMAU:

118300679(fbxw2)

LCF:

108898986

SDU:	111221261(fbxw2)

SLAL:

111648136(fbxw2)

XGL:	120806298(fbxw2)

HCQ:	109530779(fbxw2)

SSCV:

125979885(fbxw2)

SBIA:

133490473(fbxw2)

PEE:	133414226(fbxw2)

PTAO:

133489781(fbxw2)

BPEC:

110161615(fbxw2)

ENY:	140367538(fbxw2)

MALB:

109970912(fbxw2)

BSPL:

114867310(fbxw2)

SJO:	128379732(fbxw2)

SSCO:

133995248(fbxw2)

GMH:	115542770(fbxw2)

SASA:

106562903 106571134

STRU:

115203786

OTW:	112220020 112230737

OMY:	110509542 110523212

OGO:	123989456 124016645

ONE:	115118636 115147127

OKI:	109867904 109875912

OKE:

118385563

OMM:	135518323 135544751

OCLA:

139388404 139408353

SALP:

111961906 111963821

SNH:	120021630 120025465

CCLU:

121541404 121582014

ELS:	105021759(fbxw2)

OEP:	134039026(fbxw2)

SFM:	108938104(fbxw2)

PKI:	111858739(fbxw2)

AANG:

118206175(fbxw2)

AROT:

135265103(fbxw2)

CCOG:

133140744(fbxw2)

LOC:	102696878(fbxw2)

PSPA:

121309612(fbxw2)

ARUT:

117396834 117973925

PSEX:

120542204(fbxw2)

LCM:	102347014(FBXW2)

CMK:	103190627(fbxw2)

RTP:	109920979(fbxw2)

CPLA:

122564870(fbxw2)

HOC:	132825864(fbxw2)

LERI:

129711838(fbxw2)

PMRN:

116944968(FBXW2)

LRJ:	133341846(FBXW2)

BFO:

BBEL:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

FOC:

TPAL:

ZNE:	110831411 110837763

CSEC:

111863328 111866911

PAME:

138693222 138697498 138711074 138711960

BROR:

IEL:

HAMR:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

MNZ:

MRJ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

CSCU:

CVS:

PTEP:

ABRU:

UDV:	129224889 129233768

LPOL:

106467908 106472641

LGI:	LOTGIDRAFT_83266

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CVN:

OED:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

TAD:	TRIADDRAFT_31932

» show all

Reference

PMID:18703417

Authors

Chiang MH, Chen LF, Chen H

Title

Ubiquitin-conjugating enzyme UBE2D2 is responsible for FBXW2 (F-box and WD repeat domain containing 2)-mediated human GCM1 (glial cell missing homolog 1) ubiquitination and degradation.

Journal

Biol Reprod 79:914-20 (2008)
DOI:10.1095/biolreprod.108.071407

Sequence

[hsa:26190]

LinkDB

DBGET integrated database retrieval system